• Title/Summary/Keyword: Bias Tests

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Resistance Factor and Target Reliability Index Calculation of Static Design Methods for Driven Steel Pipe Pile in Gwangyang (광양지역에 적합한 항타강관말뚝의 목표신뢰성지수 및 저항계수 산정)

  • Kim, Hyeon-Tae;Kim, Daehyeon;Lim, Jae-Choon;Park, Kyung-Ho;Lee, Ik-Hyo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.12
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    • pp.8128-8139
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    • 2015
  • Recently, the necessity of developing the load and resistance factor design(LRFD) for soft ground improvement method has been raised, since the limit state design is requested as international technical standard for the foundation of structures. In this study, to develop LRFD codes for foundation structures in Korea, target reliability index and resistance factor for static bearing capacity of driven steel pipe piles were calibrated in the framework of reliability theory. The 16 data(in Gwangyang) and the 57 data(Korea Institute of Construction Technology, 2008) sets of static load test and soil property tests conducted in the whole domestic area were collected along with available subsurface investigation results. The resistance bias factors were evaluated for the tow static design methods by comparing the representative measured bearing capacities with the expected design values. Reliability analysis was performed by two types of advanced methods : the First Order Reliability Method (FORM), and the Monte Carlo Simulation (MCS) method using resistance bias factor statistics. As a result, when target reliability indices of the driven pipe pile were selected as 2.0, 2.33, 2.5, resistance factor of two design methods for SPT N at pile tip less than 50 were evaluated as 0.611~0.684, 0.537~0.821 respectively, and STP N at pile tip more than 50 were evaluated as 0.545~0.608, 0.643~0.749 respectively. The result from this research will be useful for developing various foundations and soil structures under LRFD.

A Validation Study of Retrospective Pre-post Testin the Affective Domain in Science Learning:for Scientifically Gifted Elementary Students (과학학습의 정의적 영역에서 사전-사후 통합 검사 설계의 타당화 연구: 과학영재를 대상으로)

  • Lim, Chae-Seong;Park, Hyoung-Min
    • Journal of Korean Elementary Science Education
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    • v.36 no.3
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    • pp.219-226
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    • 2017
  • In this study, the reliability and validity of the retrospective pre-post test were analyzed in order to solve the problem of traditional pre-post test including response shift bias. Samples of the study were 162 elementary school students who are studying at the S university gifted education center in Seoul. Before completion of the field trip, we conducted pre test of science-related attitudes. After completion of the field trip, respondents were asked to compare their responses of pre and post science-related attitudes to quantitatively analyze the commonalities and differences of the two tests. To find out more characteristics, qualitative data such as daily records and interview were also gathered and analyzed. The major results of the study are as follows. First, for the paired t-test, there was no statistically significant difference between separate pre-test scores and retrospective pre-test. There was a very high correlation between the separate pre-test scores and the retrospective pre-test. Second, there were significant differences in all seven sub-factors of science-related attitudes between the retrospective pre-test and the post-test. Third, the separate pre-test scores showed a slightly higher tendency than the retrospective pre-test scores. This suggests that the response shift bias appears when it is performed the separate pre-test in affective domain. As a result of the interview, it was found that the evaluation standards of separate pre-test did not match with those of post-test. Forth, internal consistency reliability of the retrospective pre-test was higher than that of the separate pre-test. However, there were significant differences in six factors of science-related attitudes excluding the 'social implications of science' between the separate pre-test and the post-test. Based on these results, the retrospective pre-post test design provides simplicity and convenience to both respondents and investigators, as it is done with one test. The retrospective pre-post test design can be regarded as a valid design for the self-report measurement of affective domain on a single experimental group.

Issues in Applying CV Methods to the Preliminary Feasibility Test (예비타당성조사 적용 CVM의 분석체계와 개선과제)

  • Eom, Young Sook;Kwon, Oh-Sang;Shin, Youngchul
    • Environmental and Resource Economics Review
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    • v.20 no.3
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    • pp.595-628
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    • 2011
  • This study investigates the issues and suggests reform measures in applying CV methods to the Korea Development Institute's (KDI's) Preliminary Feasibility Test (PFT) of public projects. Most public projects on culture, science and environment evaluated under the PFT system belong to the category of "nonstandard" projects whose outputs are non-marketed, and CV is currently the main tool used for their benefit estimation. A careful discussion and investigation is recommended for the selection of target population, payment vehicle, and number of payment times. Operating expert reviews, focus group interviews, and pre-tests is highly recommended to reduce the potential bias involved in the CV studies. A single or double bounded dichotomous choice format is the most popular design of questionnaire, but we identify several undissolved issues in designing and implementing the format. Some other forms of inducing WTPs may still deserve our consideration. Various specifications of the WTP function need to be tried and tested based on their stability, in particular. Employing a nonparametric approach is also recommended. Treatments of 0 or negative WTPs and protest bids are shown to be the most serious issues that affect the estimation results significantly. We review diverse measures of handling those issues and summarize their advantages and shortcomings.

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Prognostic Value of Matrix Metalloproteinase 9 Expression in Breast Cancer Patients: A Meta-analysis

  • Song, Jian;Su, Hong;Zhou, Yang-Yang;Guo, Liang-Liang
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.1615-1621
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    • 2013
  • Background: Matrix metalloproteinase 9 (MMP-9) is related to tumor invasion and metastasis. However, the role of MMP-9 expression in breast cancer survival remains controversial. The purpose of this study was to accomplish a more accurate estimation of the association between MMP-9 expression and survival results in breast cancer patients through meta-analysis. Methods: A meta-analysis of published studies investigating the effects of positive MMP-9 expression on both relapse free survival (RFS) and overall survival (OS) was performed. Relevant literature was confirmed by searching electronic databases including PubMed, Ovid, EMBASE and China National Knowledge Infrastructure (CNKI) before November 1, 2012. Individual hazard ratios (HRs) and 95% confidence intervals (CIs) were extracted and pooled HRs with 95% CIs were used to evaluate the strength of the association between positive MMP-9 expression and survival results of breast cancer patients. Funnel plot and Egger's regression tests were used to evaluate publication bias. Heterogeneity and sensitivity analysis was also conducted. All the work was completed using STATA. Results: A total of 2,344 patients from 15 evaluative studies were finally included. Pooled HRs and 95% CIs suggested that MMP-9 overexpression had an unfavorable impact on both OS (HR: 1.70, 95% CI: 1.41-2.04) and RFS (HR: 1.54, 95% CI: 1.17-2.01) in breast cancer patients. There was no significant heterogeneity observed in the studies reported for OS (P=0.360, $I^2$=8.8%), but not RFS (P=0.002, $I^2$=67%). Publication bias was absent among the studies both in OS and RFS cases (t=-0.54, P=0.605 and t=1.71, P=0.131, respectively). Omission of any single study had little effect on the combined risk estimates on sensitivity analysis. Conclusion: The results of this meta-analysis suggest that positive MMP-9 expression confers a higher risk of relapse and a worse survival in patients with breast cancer. Larger prospective studies are now needed to evaluate the clinical utility of MMP-9 expression.

A 30 GHz Band Low Noise for Satellite Communications Payload using MMIC Circuits (MMIC 회로를 이용한 위성중계기용 30GHz대 저잡음증폭기 모듈 개발)

  • 염인복;김정환
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.11 no.5
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    • pp.796-805
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    • 2000
  • A 30GHz band low noise amplifier module, which has linear gain of 30dB and noise figure of 2.6dB, for 30GHz satellite communication transponder was developed by use of MMIC and thin film MIC technologies. Two kinds of MMIC circuits were used for the low noise amplifier module, the first one is ultra low noise MMIC circuit and the other is wideband and high gain MMIC circuit. The pHEMT technology with 0.15$mu extrm{m}$ of gate length was applied for MMIC fabrication. Thin film microstrip lines on alumina substrate were used to interconnect two MMIC chips, and the thick film bias circuit board were developed to provide the stabilized DC bias. The input interface of the low noise amplifier module was designed with waveguide type to receive the signal from antenna directly, and the output port was adopted with K-type coaxial connector for interface with the frequency converter module behind the low noise amplifier module. Space qualified manufacturing processes were applied to manufacture and assemble the low noise amplifier module, and space qualification level of environment tests including thermal and vibration test were performed for it. The developed low noise amplifier was measured to show 30dB of minimum gain, $\pm$0.3dB of gain flatness, and 2.6dB of maximum noise figure over the desired operating frequency range from 30 to 31 GHz.

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Microscopic Investigation on the Micro-Deformation of Draped Helmet Structure Made of fabric Composite (직물 복합재료를 이용한 드레이핑 헬멧의 미소 변형 관찰)

  • 장승한
    • Composites Research
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    • v.16 no.4
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    • pp.29-35
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    • 2003
  • In this paper. various tow parameters such as equivalent tow thickness, amplitude of longitudinal tow and tow intervals were investigated and compared with each other by using microscopic observation to find out the exact deformation patterns between both directions of the fabric structure(Longitudinal and Transverse Directions). And those observation results were compared with bias extension. biaxial tests results with dry fabric which has the same tow structure as the draped helmet materials and also compared with prepreg specimen which is cured by autoclave moulding without vacuum and pressure condition. Specimens for the observation were taken from draped helmet which is made of fabric composite(Five Harness Satin Weave). From the observation results, it was found that there are different deformation pattern between tow directions and effect of geometric condition on the deformation of the fabric materials during draping process was verified.

The RTEL1 rs6010620 Polymorphism and Glioma Risk: a Meta-analysis Based on 12 Case-control Studies

  • Du, Shu-Li;Geng, Ting-Ting;Feng, Tian;Chen, Cui-Ping;Jin, Tian-Bo;Chen, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10175-10179
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    • 2015
  • Background: The association between the RTEL1 rs6010620 single nucleotide polymorphism (SNP) and glioma risk has been extensively studied. However, the results remain inconclusive. To further examine this association, we performed a meta-analysis. Materials and Methods: A computerized search of the PubMed and Embase databases for publications regarding the RTEL1 rs6010620 polymorphism and glioma cancer risk was performed. Genotype data were analyzed in a meta-analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association. Sensitivity analyses, tests of heterogeneity, cumulative meta-analyses, and assessments of bias were performed in our meta-analysis. Results: Our meta-analysis confirmed that risk with allele A is lower than with allele G for glioma. The A allele of rs6010620 in RTEL1 decreased the risk of developing glioma in the 12 case-control studies for all genetic models: the allele model (OR=0.752, 95%CI: 0.715-0.792), the dominant model (OR=0.729, 95%CI: 0.685-0.776), the recessive model (OR=0.647, 95%CI: 0.569-0.734), the homozygote comparison (OR=0.528, 95%CI: 0.456-0.612), and the heterozygote comparison (OR=0.761, 95%CI: 0.713-0.812). Conclusions: In all genetic models, the association between the RTEL1 rs6010620 polymorphism and glioma risk was significant. This meta-analysis suggests that the RTEL1 rs6010620 polymorphism may be a risk factor for glioma. Further functional studies evaluating this polymorphism and glioma risk are warranted.

Effect of Proactive Personality on the Upward Influence: Focusing on Mediating Effect of Political Skill (주도적 성격이 상향 영향력에 미치는 영향: 정치적 기술의 매개효과를 중심으로)

  • Kang, Kyung-Goo;Kim, Jung-Hoon
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.527-540
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    • 2015
  • The current study empirically tests the mediating effects of political skills on the relationship between proactive personality and upward influence. In this study, we attempted to mitigate common method bias by collecting data from two sources. 275 pairs of returned questionnaires were utilized to verify the hypotheses. According to the hierarchical regression, proactive personality and 4 political skills have impact on upward influence positively. proactive personality was positively related to political skills. In addition social astuteness, interpersonal influence and apparent sincerity mediate relationship between proactive personality and upward influence. but networking ability does not have mediating effect. Based on these results, implications and limitations of this study arediscussed and future research direction are suggested.

A Study on Brassiere Development for the New Silver Generation Women (뉴실버세대 여성을 위한 브래지어 개발)

  • Park, Ja Young;Jang, Jeong Ah
    • Fashion & Textile Research Journal
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    • v.17 no.3
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    • pp.429-439
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    • 2015
  • This study develops a new brassiere for new silver women. A new brassiere design was developed for the silver generation based on apreliminary survey; subsequently, a wire and no-wire type of brassier were developed after a second fitting evaluation. The results were as follows. First, in terms of brassiere design, the cup shape was designed as mold type full cup, shoulder straps were designed as camisole type with cups, bias tape was designed for body correction in the side line and mash tape was designed for easy movement below the cups. On the other side ofthe cup shape was a pocketdesigned on a support pad forthe wire type and a support panel to serve as a wire in the no-wire type brassiere. Second, brassiere patterns were designed by referencing the educational H pattern. Thetotal length was elongated by 5cmto reduce pressure when wearing a brassiere and the height of the front center increased by 8cm for the stability of the front center of the brassiere. In addition, the side line was moved back by 3cm and the width of the brassiere wings was designed widely at 10.5cm. Third, a wearing test was conducted for the wire type and the no-wire type brassiere with comparison products, using a 7-point Likert scale. Appearance results and movement tests for the wire and no-wire type showed a higher score than comparison products.

Simultaneous Quantification of Oleins (triolein, diolein and monoolein) in Mouse Feces using Liquid Chromatography-Electrospray Ionization/Mass Spectrometry

  • Lim, Jong-Hyun;Lee, Jeong-Ae;Jang, Yu-Ra;Chung, He-Sson;Lee, Won-Yong;Chung, Bong-Chul
    • Mass Spectrometry Letters
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    • v.3 no.3
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    • pp.68-73
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    • 2012
  • Fat malabsorption is an important cause of poor growth in infancy and childhood. Steatorrhea tests have been developed using various methods. Traditional measurements of stool fat, however, require large samples and it often takes as a week to complete the analysis. In this paper, a liquid chromatography-electrospray ionization/mass spectrometry (LC-ESI/MS) method was developed for simultaneous quantitative analysis of triacylglycerols, triolein, diolein and monoolein, in mouse feces. Moreover, the procedure was rapid, simple as well as compatible with LC-ESI/MS. Chloroform-isopropyl alcohol solution was used for fat-soluble sample extraction. After centrifugation and filtration, an analytical solution was prepared. Triolein, diolein and monoolein were separated using non-aqueous reversed-phase column with the mobile phase consisting of A (methanol) and B (acetone-isopropyl alcohol). The precision (% CV) and accuracy (% bias) of the assay were 3.8-14.7% and 85.2-114.9%, respectively. This method has been successfully applied to simultaneous determination of triolein, diolein and monoolein in feces from 30 mice. This method can therefore be applied to measure triacylglycerols in mouse feces accurately and precisely by LC-ESI/MS, thereby helping to predictive biomarker in fat malabsorption and diagnostic research.