• Journal of Genetic Medicine
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• v.2 no.1
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• pp.1-5
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• 1998

A female hemihypertrophy patient with hypomelanosis of Ito is presented as a rare case combining classical features of both the syndrome. Chromosomal profile has been based on longitudinal study of repeated lymphocyte cultures during 1984-1992. The propositus has exhibited chromosomal mosaicism both hypoploid ($42{\pm}1$) and hyperploid ($48{\pm}2$ chromosome) counts, but the major stem line presented 46XX chromosomes. Ring chromosome with simple and complex translocations with marker dots appear to be the major cytogenetic assemblage of this child to posses unequal left and right halves of the body. Each and every organ from toe to the head has grown up unequally and lately the patient had been exhibiting different dark and light shapes of melanin on the skin. We believe that the patient had inherited, through her male parent, "a few" mutated loci on some chromosomes so as to generate different cell lines within the developing child. All sibs and the mother showed normal karyotype with no apparent aberration.

• Journal of Korea Multimedia Society
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• v.6 no.4
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• pp.668-675
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• 2003

Now a days many industries and bigger organisation (Indian Railways, Bharat Heavy Electricals Ltd.) are facing difficulties in implementing the new technology because of non-availability of fully trained staff. Also for the employed technical and other staff lot of resistance management has to face to get them trained for adoption of new technology. There are also very less organisations who can design effective training programmes and at the same time develop course material specially multimedia packages and computer base training (CBT) which can satisfy the need of different target groups of industries. Indian Railways was also facing similar situation while implementing the Air Brake System technology In Indian Railways. TTTI Bhopal took that challenge and designed, developed and trained Indian Railways trainer for implementation of the package on different target group. The present paper offers a case study on the same.

• The Journal of Asian Finance, Economics and Business
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• v.2 no.2
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• pp.35-38
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• 2015

Managers, supervisors, executives and others whose office is to get work done by staff in organizations would desire a motivated workforce. Despite the advances in technology, any system has tot have motivated people to achieve its goals and at some time or other, no one in charge of a unit has failed to wonder, 'How best do I get individuals and groups motivated'? What is motivation, how can employees be motivated to direct their energies towards execution of the job and how is this achieved on a sustained on-going basis? Is a highly motivated employee necessarily an ace performer? These are the issues which the author would address in the present paper. The authors has conducted an empirical study by administering motivational test and collected data from 100 corporate of Bhopal region.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.10
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• pp.4409-4419
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• 2015

The Bhopal gas tragedy involving methyl isocyanate (MIC) is one of the most horrific industrial accidents in recent decades. We investigated the genotoxic effects of MIC in long-term survivors and their offspring born after the 1984 occurrence. There are a few cytogenetic reports showing genetic damage in the MIC-exposed survivors, but there is no information about the associated cancer risk. The same is true about offspring. For the first time, we here assessed the micronucleus (MN) frequency using cytokinesis-blocked micronucleus (CBMN) assay to predict cancer risk in the MIC-affected population of Bhopal. A total of 92 healthy volunteers (46 MIC-affected and 46 controls) from Bhopal and various regions of India were studied taking gender and age into consideration. Binucleated lymphocytes with micronuclei (BNMN), total number of micronuclei in lymphocytes (MNL), and nuclear division index (NDI) frequencies and their relationship to age, gender and several lifestyle variabilities (smoking, alcohol consumption and tobacco-chewing) were investigated. Our observations showed relatively higher BNMN and MNL (P<0.05) in the MIC-affected than in the controls. Exposed females (EF) exhibited significantly higher BNMN and MNL (P<0.01) than their unexposed counterparts. Similarly, female offspring of the exposed (FOE) also suffered higher BNMN and MNL (P<0.05) than in controls. A significant reduction in NDI (P<0.05) was found only in EF. The affected group of non-smokers and non-alcoholics featured a higher frequency of BNMN and MNL than the control group of non-smokers and non-alcoholics (P<0.01). Similarly, the affected group of tobacco chewers showed significantly higher BNMN and MNL (P<0.001) than the non-chewers. Amongst the affected, smoking and alcohol consumption were not associated with statistically significant differences in BNMN, MNL and NDI. Nevertheless, tobacco-chewing had a preponderant effect with respect to MNL. A reasonable correlation between MNL and lifestyle habits (smoking, alcohol consumption and tobacco-chewing) was observed only in the controls. Our results suggest that EF and FOE are more susceptible to cancer development, as compared to EM and MOE. The genotoxic outcome detected in FOE reflects their parental exposure to MIC. Briefly, the observed cytogenetic damage to the MIC-affected could contribute to cancer risk, especially in the EF and FOE.

• Journal of Information Science Theory and Practice
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• v.2 no.2
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• pp.33-47
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• 2014

Mobile devices are the most important equipment for accessing various kinds of services. These services are accessed using wireless signals, the same used for mobile calls. Today mobile services provide a fast and excellent way to access all kinds of information via mobile phones. Mobile service providers are interested to know the access behavior pattern of the users from different locations at different timings. In this paper, we have introduced an associated tree for analyzing user behavior patterns while moving from one location to another. We have used four different parameters, namely user, location, dwell time, and services. These parameters provide stronger frequent accessing patterns by matching joins. These generated patterns are valuable for improving web services, recommending new services, and predicting useful services for individuals or groups of users. In addition, an experimental evaluation has been conducted on simulated data. Finally, performance of the proposed approach has been measured in terms of efficiency and scalability. The proposed approach produces excellent results.

• Journal of the Korean Mathematical Society
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• v.61 no.1
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• pp.1-28
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• 2024

In this article, we associate a contact structure to the conjugacy class of a periodic surface homeomorphism, encoded by a combinatorial tuple of integers called a marked data set. In particular, we prove that infinite families of these data sets give rise to Stein fillable contact structures with associated monodromies that do not factor into products to positive Dehn twists. In addition to the above, we give explicit constructions of symplectic fillings for rational open books analogous to Mori's construction for honest open books. We also prove a sufficient condition for the Stein fillability of rational open books analogous to the positivity of monodromy for honest open books due to Giroux and Loi-Piergallini.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5323-5324
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• 2012

• Journal of Internet Computing and Services
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• v.17 no.5
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• pp.97-110
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• 2016

Cryptanalysis is very important step for auditing and checking strength of any cryptosystem. Some of these cryptosystem ensures confidentiality and security of large information exchange from source to destination using symmetric key cryptography. The cryptanalyst investigates the strengths and identifies weakness key as well as enciphering algorithm. With increase in key size the time and effort required to guess the correct key increases so trend is increase key size from 8, 16, 24, 32, 56, 64, 128 and 256 bits to strengthen the cryptosystem and thus algorithm continues without compromise on the cost of time and computation. Automatic Variable Key (AVK) approach is an alternative to the approach of fixing up key size and adding security level with key variability adds new dimension in the development of secure cryptosystem. Likewise, whenever any new cryptographic method is invented to replace per-existing vulnerable cryptographic method, its deep analysis from all perspectives (Hacker / Cryptanalyst as well as User) is desirable and proper study and evaluation of its performance is must. This work investigates AVK based cryptic techniques, in future to exploit benefits of advances in computational methods like ANN, GA, SI etc. These techniques for cryptanalysis are changing drastically to reduce cryptographic complexity. In this paper a detailed survey and direction of development work has been conducted. The work compares these new methods with state of art approaches and presents future scope and direction from the cryptic mining perspectives.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.599-603
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• 2014

Background: Reproductive cancers are those that affect the human organs that are involved in producing offspring. An attempt is made in the present communication to assess the magnitude and pattern of reproductive cancers, including their treatment modalities, in India. The cancer incidence data related to reproductive cancers collected by five population-based urban registries, namely Bangalore, Bhopal, Chennai, Delhi and Mumbai, for the years 2006-08 were utilized. The reproductive cancers among females constituted around 25% of the total and around 9% among males. Among females, the three major contributors were cervix (55.5%), ovary (26.1%) and corpus uteri (12.4%). Similarly among males, the three major contributors were prostate (77.6%), penis (11.6%) and testis (10.5%). For females, the AAR of reproductive cancers varied between 30.5 in the registry of Mumbai to 37.3 in the registry of Delhi. In males, it ranged between 6.5 in the registry of Bhopal to 14.7 in the registry of Delhi. For both males and females, the individual reproductive cancer sites showed increasing trends with age. The leading treatment provided was: radio-therapy in combination with chemo-therapy for cancers of cervix (48.3%) and vagina (43.9%); surgery in combination with chemo-therapy (54.9%) for ovarian cancer; and surgery in combination with radio-therapy for the cancers of the corpus uteri (39.8%). In males, the leading treatment provided was hormone-therapy for prostate cancer (39.6%), surgery for penile cancer (81.3%) and surgery in combination with chemo-therapy for cancer of the testis (57.6%).

• Natural Product Sciences
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• v.26 no.4
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• pp.259-267
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• 2020

Snakebite is a severe medical, economic, and social problem across the world, mostly in the tropical and subtropical area. These regions of the globe have typical of the world's venomous snakes present where access to prompt treatment is limited or not available. Snake venom is a complex mixture of toxin proteins like neurotoxin and cardiotoxin, and other enzymes like phospholipase A2 (PLA2), haemorrhaging, transaminase, hyaluronidase, phosphodiesterase, acetylcholinesterase, cytolytic and necrotic toxins. Snake venom shows a wide range of biological effects like anticoagulation or platelet aggregation, hemolysis, hypotension and edema. Phospholipase A2 is the principal constituent of snake venom; it catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid, which is the precursor of eicosanoids including prostaglandins and leukotrienes. The information regarding the structure and function of the phospholipase A2 enzyme may help in treating the snakebite victims. This review article constitutes a brief description of the structure, types, mechanism occurrence, and tests of phospholipase A2 and role of components of medicinal plants used to inhibit phospholipase A2.