• Korean Journal of Medicinal Crop Science
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• v.17 no.6
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• pp.464-469
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• 2009

This study was conducted to find out environment-friendly disease control method to Alternaria blight caused by Alternaria panax of ginseng. For this study, 150 methanol extracts from medicinal plants were evaluated and the extract of Impatiens balsamina showed most strong antifungal activity against A. panax. The methanol extract of I. balsamina showed also stable antifungal activity against other ginseng pathogens such as Botrytis cinerea and Fusarium sp., when treated by heat or pH. In vivo, Alternaria blight incidence rate was low of 13% with the treatment of I. balsamina methanol extract compared to 35% of the non-treatment. The antifungal compound of I. balsamina was purified and identified by using a silica gel column chromatography, TLC and ESI-LC/MS/MS analysis. The compound which showed strong antifungal activity was identified as 2-methoxy-1,4-naphtoquinone ($C_{11}H_8O_3$).

• Genomics & Informatics
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• v.8 no.3
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• pp.101-102
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• 2010

During the last decade, large community cohorts have been established by the Korea National Institutes of Health (KNIH), and enormous epidemiological and clinical data have been accumulated. Using these information and samples in the cohorts, KNIH set out to do a large-scale genome-wide association study (GWAS) in 2007, and the Korea Association REsource (KARE) consortium was launched to analyze the data to identify the underlying genetic risk factors of diseases and diverse health indexes, such as blood pressure, obesity, bone density, and blood biochemical traits. The consortium consisted of 6 research divisions, formed by 25 principal investigators in 19 organizations, including 18 universities, 2 institutes, and 1 company. Each division focused on one of the following subjects: the identification of genetic factors, the statistical analysis of gene-gene interactions, the genetic epidemiology of gene-environment interactions, copy number variation, the bioinformatics related to a GWAS, and a GWAS of nutrigenomics. In this special issue, the study results of the KARE consortium are provided as 9 articles. We hope that this special issue might encourage the genomics community to share data and scientists, including clinicians, to analyze the valuable Korean data of KARE.

• Korean Journal of Soil Science and Fertilizer
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• v.33 no.2
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• pp.121-126
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• 2000

Composition of fungal communities in three microhabitats such as soil, rhizosphere and rhizoplane were studied to understand the root environment of healthy and diseased plants in Phytophthora non-infested and infested fields, respectively. Samples were collected from the tomato- and red pepper-growing greenhouses in Kyungsang-Nam Province on April, 1999. Twenty-five species were isolated from each vegetation field using the dilution plate technique. There were a greater variety of species in infested fields than non-infested and in soils than in both rhizospheres and rhizoplanes. The number of species isolated were varied amongst the different microhabitats. A Trichoderma species was isolated only from non-infested fields.

• Journal of Korean Port Research
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• v.8 no.2
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• pp.37-56
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• 1994

The effects of wave energy focusing by a submerged berm type of structure is examined. The fundamental idea is based on the phenomenon of refraction by a lens-shaped crescent structure which results in the focusing of wave energy on the center line of the structure. The shape of the submerged structure is a complex curve combining circular with elliptical elements. Based on the design procedure, a special configuration of structure(termed herein as a triple crescent structure) is introduced. Next, some hydraulic model tests are performed to confirm the wave focusing effect in laboratory. In addition, in order to interpret the wave focusing performance behind the structure, a numerical procedure by the hybrid element method is used on the basis of the conventional mild slope equation but modified and extended to allow for steeper bottom slopes and higher curvature. The modified refraction and diffraction provide additional mechanism for wave height amplification and the maximum amplification for triple crescent structure is presented. It also allows for the possibility of wave energy scattering with the change of the incident wave direction. Comparisons with previous theoretical results involving a submerged crescent shape structure are described.

• Journal of The Geomorphological Association of Korea
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• v.18 no.3
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• pp.83-92
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• 2011

The properties and changes of geomorphic relief and coastal deposits were analyzed at Goreabul sand beach in Yeongdeok-gun, the largest that in east coast of Kyungsangbuk-do Province. As the result of grain size analysis, in almost season except summer, the sands mainly deposited in Goraebul sand beach because longshore current drift northward contrary to Gangwon-do east coast, and summer longshore current is weak or change direction to south ward. Sand beach mostly came form erosion owing to typoon and storm and was deposit more coarse sand in the summer, and was produced deposition actively in the fall and winter. Front side of sand dune came from deposition on sand every season by sea breeze, especially in the winter.

• Genomics & Informatics
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• v.6 no.4
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• pp.173-180
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• 2008

The human genome has evolved as a consequence of evolutionary forces, such as natural selection. In this study, we investigated natural selection on the human genes by comparing the numbers of nonsynonymous (NS) and synonymous (S) mutations in individual genes. We initially collected all coding SNP data of all human genes from the public dbSNP. Among the human genes, we selected 3 different selection groups of genes: positively selected genes (NS/S${\geq}$3), negatively selected genes (NS/S${\leq}$1/3) and neutral selection genes (0.9

• Korean Journal of Organic Agriculture
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• v.21 no.4
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• pp.737-752
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• 2013

This study was conducted to evaluate the allelopathic effect of aqueous extract of Ganghwa domestic mugwort (Artemisia spp.) on vegetables and its related allelo-chemicals. When the receptor vegetables, such as Chinese cabbage, lettuce, and red radish, were treated with aqueous extract obtained from Sajabalssuk (A. $sp^*I$), Ssajuarissuk (A. $sp^*II$) or Ssajarissuk (A. $sp^*III$), their germination rate, leaf number, plant height, and root length were restricted with increasing concentration of aqueous extract. Allelopathic effect was the highest in radish, than lettuce and Chinese cabbage in order. The growth of topplant were more inhibited then root growth observing in restriction of plant height, root length, and chlorophyll contents. The plant height, the root length of red radish were 53.3 and 61.2% and their fresh weights were 19.8 and 26.4% compared to those of controls, respectively. A. $sp^*III$ showed the highest allelopathic effect among the donor plants. In HPLC analysis, 7 phenol compounds were identified in A. $sp^*I$ and A. $sp^*II$, and, in A. $sp^*III$, and hydroxybenzoic acid and phenylacetic acid were further identified as allelochemicals. It is considered that their plant growths were variously inhibited by the amounts and types of allelochemicals in aqueous extracts. To increase the productivity of farm land after cultivation of mugwort, these results can be useful to select the following field crops.

• Journal of Digital Convergence
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• v.10 no.10
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• pp.237-245
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• 2012

This study deals with the influencing factors for satisfaction and the emotional value perception of mobile voucher service user. Thus researcher examined a structural equation modeling methodology of the paths within word of mouth, satisfaction, and other exogenous variables (economic/rational value, trust, joyfulness, innovativeness). As a result of this study, First, it was confirmed that the emotional value, and innovativeness affected user's trust for coupon service and joyfulness for using mobile voucher. Second, it was confirmed that trust and joyfulness affected user's satisfaction and word of mouth activities. Therefore, in cases of utilizing the emotional appeal of mobile voucher as part of a marketing tool, corporate can maximize efficiency by using their mobile voucher service & event from the point of view of customer's satisfaction & voluntary word of mouth. Researcher's consideration is that this paper's theoretical and practical contribution point is the propose of the one of the post adoption model with the quantitative study of the mobile voucher service user's emotional perception in the initial development stages of high-tech industry.

• Genomics & Informatics
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• v.10 no.1
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• pp.40-43
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• 2012

Recent genomewide association studies of large samples have identified genes that are associated with blood pressure. The Global Blood Pressure Genetics (Global BPgen) and Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) consortiums identified 14 loci that govern blood pressure on a genomewide significance level, one of which is $CASZ1$ confirmed in both Europeans and Asians. $CASZ1$ is a zinc finger transcription factor that controls apoptosis and cell fate and suppresses neuroblastoma tumor growth by reprogramming gene expression, like a tumor suppressor. To validate the function of $CASZ1$ in blood pressure, we decreased $Casz1$ mRNA levels in mice by siRNA. $Casz1$ siRNA reduced mRNA levels by 59% in a mouse cell line. A polyethylenimine-mixed siRNA complex was injected into mouse tail veins, reducing $Casz1$ mRNA expression to 45% in the kidney. However, blood pressure in the treated mice was unaffected, despite a 55% reduction in $Casz1$ mRNA levels in the kidney on multiple siRNA injections daily. Even though $Casz1$ siRNA-treated mice did not experience any significant change in blood pressure, our study demonstrates the value of $in$ $vivo$ siRNA injection in analyzing the function of candidate genes identified by genomewide association studies.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.30 no.5
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• pp.207-216
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• 2018

This research compared and analyzed safety ratio of slope with Talren97 and SoilWorks based on limit equilibrium analysis and Midas GTS based on finite element analysis. For the analysis variables, there are slope height, berm condition, soil parameter, groundwater level, slope inclination. All of slope stability analysis were performed by dividing into dry season and rainy season. As the result of the analysis of Talren97 and SoilWorks based on same theory, safety ratio of slope shows same value, so there was no difference between the programs. In comparison with limit equilibrium analysis, the result of finite element analysis showed somewhat high ratio of safety and it was higher by about 2.4% averagely. The difference between the result of limit equilibrium analysis and that of finite element analysis is in the range which can ignored in practical work.