• Title/Summary/Keyword: Benzyl chloroformate (Cbz-Cl)

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A Simple, Efficient, Catalyst-Free and Solvent-Less Microwave-Assisted Process for N-Cbz Protection of Several Amines

  • Aouf, Zineb;Mansouri, Rachida;Lakrout, Salah;Berredjem, Malika;Aouf, Nour-Eddine
    • Journal of the Korean Chemical Society
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    • v.61 no.4
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    • pp.151-156
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    • 2017
  • A simple, green and chemo-selective method for the N-benzyloxycarbonylation of amines, ${\beta}$-amino alcohols, ${\alpha}$-amino esters and sulfonamides has been developed under microwave irradiation. Good to excellent yields of the N-benzyloxycarbamates compounds were obtained in short times without any side products.