• Journal of Korean Neurosurgical Society
• /
• 제60권3호
• /
• pp.371-374
• /
• 2017

Ganglioneuroma (GN) is a rare benign tumor of neural crest origin usually found in the abdomen, but may occasionally present at uncommon sites including the cervical, lumbar, or sacral spine. However, GNs of thoracic spine are extremely rare. In this report, we describe a 12-year-old girl with giant GN in the thoracic spine, who underwent successful resection (T1-4 level) of the tumor. Histopathological examination confirmed the diagnosis. GN should be considered in the differential diagnosis of any paraspinal mass. A high index of suspicion and correlation of clinico-radiological findings is necessary in differentiating a large benign tumor from a malignant growth. Complete surgical excision is the treatment of choice; however tumor size and location need to be considered for the surgical approach (one-step or multiple surgeries). Close follow-up after surgery is mandatory.

• Archives of Plastic Surgery
• /
• 제40권3호
• /
• pp.244-246
• /
• 2013

Lipomas are benign mesenchymal tumors that develop in areas of abundant adipose tissue. Due to the fatty composition of the breast, difficulties in diagnosis, treatment, and reconstruction are often encountered. We report a case of a 55-year-old female with a giant tumor of the right breast that comprised most of its mass, causing breast asymmetry. A thorough preoperative evaluation, followed by an uneventful difficult surgical resection and reconstruction, resulted in diagnosis of a benign lipoma. The case prompted this report because of its challenging size, location, diagnosis, and reconstructive solution.

• Archives of Plastic Surgery
• /
• 제32권6호
• /
• pp.770-772
• /
• 2005

Nodular fasciitis is an unusual benign tumor which is composed of myofibroblast. Typical histologic findings include haphazardly arranged pleomorphic arranged spindle cells in a myxoid stroma. These lesions may easily be misinterpreted as malignancy clinically and histologically because it presents as a rapidly growing mass from subcutaneous or deep fascia. These lesions are usually located over upper extremity and rarely in the head and neck region. It's important to emphasize the need of clinical suspicion and accurate histopathology of this rare benign lesion usually misdiagnosed as a malignacy to avoid unnecessary and inappropriate aggressive wide resection, when encountering subcutaneous nodules of the face and neck region. In this article, we report a rare case of Nodular fasciitis on the Nose and some reviews of the literature.

• 대한세포병리학회지
• /
• 제2권2호
• /
• pp.148-152
• /
• 1991

A mediastinal mass was aspirated by fluoroscope-guided fine needle aspiration biopsy in a 47 years old female patient. The first aspiration smears were not diagnostic, because of hemorrhagic background and cell paucity. On the second aspiration, the smears were composed of some clusters of benign epithelial cells in hemorrhagic back-ground. Cells were arranged in mostly solid sheets and tended to form glandular lumina in part. Their nuclei were round and vesicular. Nucleoli were not prominent. These findings were suggestive of benign glandular tissue, which was finally confirmed as mediastinal thyroid gland by open thoracotomy specimen.

• 대한기관식도과학회지
• /
• 제5권1호
• /
• pp.96-101
• /
• 1999

For many years it has been reported that seemingly benign neck cysts may contain carcinoma. Cystic metastases have often mistaken for either branchial cleft cysts or benign mass. Authors experienced two cases which presents cystic cervical metastatic cancer One was a tonsillar carcinoma and the other was a tongue carcinoma. Patients with a cystic squamous carcinoma in the neck likely have a primary in upper aero-digestive system and It is known that the tonsil is most common site. Radiologic examination and fine needle aspiration biopsy of the cyst proved to be non-diagnostic. The development of cervical lymph node metastases before clinical signs of carcinoma of the tonsil is also well recognized. So, in old patients, thorough head If neck examination, panendoscopy and ipsilateral tonsillectomy is mandatory to identify a primary carcinoma prior to cyst excision.

• Archives of Hand and Microsurgery
• /
• 제23권4호
• /
• pp.277-280
• /
• 2018

Turrets exostosis are extremely rare to occur. Benign bony outgrowths from the dorsum of the phalanges following trauma are termed Turrets exostosis. We report an unusual case of Turrets exostosis of the fourth finger with no preceding trauma which has never been reported before. A 50-year-old female patient presented to us with a bony swelling on the dorsum of the fourth finger of her right hand in one year. The swelling was dormant initially and started to progress in size since three months leading to pain, restriction of movements and deformity of the finger. Turrets exostosis are very rare to occur. A preceding history of trauma is not necessary for it to occur as described in the literature. Surgical excision yields good results and is indicated when the bony mass causes a progressive deformity of the finger and restriction of movements of the finger.

• Tuberculosis and Respiratory Diseases
• /
• 제49권2호
• /
• pp.231-236
• /
• 2000

10년전 자궁근종으로 자궁전절제술을 시행받은 39세 여자환자로 기침을 주소로 내원하여 흉부 단순촬영, 흉부 전산화 단층촬영상 좌측상엽기관지에 연하여 3$\times$4cm크기 종괴 및 우하부 기저부에 5mm크기의 소결절이 관찰되어, 좌측 상엽 절제술을 시행받았다. 종괴의 병리조직소견상 유사분열을 보이는 세포가 50개의 고배율시야당 2-3개 정도이었으며 세포의 이형성은 관찰할 수 없었고 면역조직화학염색상 Smooth muscle actin, Vimentin, Desmin에 양성반응을 보여 평활근종임을 확인하였다. 수술 후 별다른 증상의 호소는 없었고, 경과 추적 관찰중 우측 폐에 새로운 결절이 발견되어 양성 전이성 평활근종으로 확진하였으며, 이에 문헌고찰과 함께 보고하는 바이다.

• 대한기관식도과학회지
• /
• 제17권2호
• /
• pp.120-123
• /
• 2011

A bronchogenic cyst is an uncommon benign congenital anomaly of the primitive ventral forgut which was generally encountered within the mediastinum and detected in pediatric patients. It is rarely detected in adult population as a lateral neck mass. We have recently experienced one case of bronchogenic cyst as a left lateral neck mass in a 49-year-old male. He complaints of a $2{\times}1$ cm sized, soft, non tender, and movable mass on the low lateral neck. The surgical excision of mass was performed and the final histopathologic diagnosis was a bronchogenic cyst. Here, we report this case with the review of literatures.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권4호
• /
• pp.2443-2446
• /
• 2013

Published data have shown that the levels of vascular endothelial growth factor (VEGF) and soluble VEGF receptor-1 (sVEGFR-1) in plasma and pleural effusion might be usefulness for lung cancer diagnosis. Here, we performed a prospective study to investigate the utility of VEGF and sVEGFR-1 in bronchoalveolar lavage fluid (BALF) for differential diagnosis of primary lung cancer. A total of 56 patients with solitary pulmonary massed by chest radiograph or CT screening were enrolled in this study. BALF and plasma samples were obtained from all patients and analyzed for VEGF and sVEGFR-1 using a commercially available sandwich ELISA kit. The results showed that the levels of VEGF in BALF were significantly higher in patients with a malignant pulmonary mass compared with patients with a benign mass (P < 0.001). However, no significant difference of sVEGFR-1 in BALF was found between malignant and non-malignant groups (P = 0.43). With a cut-off value of 214 pg/ml, VEGF showed a sensitivity and specificity of 81.8% and 84.2%, respectively, in predicting the malignant nature of a solitary pulmonary mass. Our study suggests that VEGF is significantly increased in BALF among patients with lung cancer than in benign diseases. Measurement of VEGF in BALF might be helpful for differential diagnosis of primary lung cancer.

• 대한세포병리학회지
• /
• 제9권1호
• /
• pp.55-61
• /
• 1998

To compare the diagnostic yields and complication rates of transthoracic fine needle aspiration cytology(FNAC) and gun biopsy in the diagnosis of pulmonary mass, a retrospective review was performed in 125 cases. Under the fluoroscopic guide, FNAC was performed by 20G Chiba needle in 91 cases, core biopsy was done by 18.5 G vaccum needle attached with automated biopsy gun in 74 cases and both procedures were done together in 37 cases. Overall sensitivity was 88.4% in FNAC and 87.5% in gun biopsy. For malignant pulmonary tumors, correct type correlation with final diagnosis was obtained in 33(76.7%) out of 43 cases by FNAC and 30(75.0%) out of 40 cases by gun biopsy. For benign pulmonary lesions, there were correct type correlation in 14(35.0%) out of 40 cases by FNAC and 14(53.8%) out of 26 cases by gun biopsy. The complication was pneumothorax and hemoptysis. Pneumothorax occured in 11.1% of FNAC, 10.9% of gun biopsy and 10.9% of both technique, among which chest tube drainages were necessary in one patient by gun biopsy and in three patients by both technique. Although no significant difference of diagnositc accuracy and complication rate was found between FNAC and gun biopsy, gun biopsy was more helpful in the diagnosis of pulmonary benign lesions than FNAC.