• 제목/요약/키워드: Benefit ratio

검색결과 594건 처리시간 0.031초

Prognostic Factors for Survival of Patients with Extensive Stage Small Cell Lung Cancer - a Retrospective Single Institution Analysis

  • Wu, Chao;Li, Fang;Jiao, Shun-Chang
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.4959-4962
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    • 2012
  • The objective of this retrospective study was to investigate prognostic factors associated with survival of patients with extensive stage small cell lung cancer (ES-SCLC). Included were 200 patients admitted to the Liberation Army General Hospital with a diagnosis of ES-SCLC. The demographics of patients, disease characteristics, pre-treatment biochemical parameters and therapeutic plan were assessed or evaluated. Univariate analysis found that second-line chemotherapy, radiotherapy, and no liver metastasis were associated with improved survival. Tumor response to first-line chemotherapy and normal initial hemoglobin levels were also associated with a survival benefit (all P-values ${\leq}$ 0.0369). Multivariate Cox regression analysis indicated that liver metastasis and the total number of all chemotherapy cycles were independent prognostic factors of survival. The morbidity risk in patients with liver metastasis was 2.52-fold higher than that in patients without liver metastasis (hazard ratio (HR)=2.52 (1.69-3.76); P<0.0001). However, one unit increase in the total number of chemotherapy cycles decreased the risk of death by 0.86-fold (HR=0.86 (0.80-0.92); P<0.0001). Absence of liver metastasis and ability of a patient to receive and tolerate multiple lines of chemotherapy were associated with longer survival.

Application of Optimum Multiparameter Analysis on Seawater Mixing in the South Sea of Korea Using Ra Isotopes

  • Lee Tongsup;Yang Han-Soeb;Kim Hyang-Bae
    • Fisheries and Aquatic Sciences
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    • 제3권2호
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    • pp.143-150
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    • 2000
  • Assuming that summer surface waters in the South Sea (northern East China Sea) are formed mostly by a mixing of three source water (Changjiang Discharge Water; Kuroshio Water and Yellow Sea Surface Water) we apply optimum multiparameter (OMP) analysis to calculate the mixing ratio of each source water to a given surface water. Since OMP requires more parameters than the number of water types (three in this study), we utilize two radium isotopes of dissolved $^{226}Ra\;and\;^{228}Ra$ along with temperature and salinity. Parameter values of each source water are deduced from in situ and historical data. Results with three source of waters on the surface waters are quite promising with less than $1\%$ of unanswered portions. Results not only reproduce the measured temperature and salinity faithfully but also discern the water masses of similar T and S according to their source water mixing. Extending OMP analysis to a whole water column obviously requires more parameters because more source waters are involved in the water mass formation. Original OMP routine utilized dissolved oxygen and nutrients. However, they seem to be perturbed too much by biological activities in the case of shallow waters. We discussed the use of other potential parameters. Also the benefit of parameter substitution is briefly introduced for the future OMP application on shallow waters.

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ECONOMIC BENEFITS OF SUPPLEMENTING LAMBS WITH UREA MOLASSES BLOCKS ON RANGES OF PAKISTAN

  • Rafiq, M.;Jadoon, J.K.;Mahmood, K.;Naqvi, M.A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제9권2호
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    • pp.127-132
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    • 1996
  • Effects on feed intake, liveweight gain and economic benefits of supplementing lambs with urea molasses blocks, were studied. Forty eight crossbred lambs were divided into 6 groups and assigned randomly to grazing on native pasture (CONT) or along with supplements of Commercial ration (COM) and urea molasses blocks (UMBs) containing two levels of cement and calcium oxide as a binding agent. Analysis of variance revealed highly significant (p<0.01) differences in dry matter (DMI, g/day), crude protein (CPI, g/day) and metabolizable energy (MEI, MJ/day) intakes. Differences in liveweight gain (LWG, g/day), feed conversion ratio (FCR) and net economic benefit of supplementation were also highly variable. The intake of DM, CP and ME varied from 974 to 1002, 66-70 and 7.6-8.4 in lambs supplemented with UMBs, significantly (p<0.01) greater than 848, 52.5 and 5.6 in lambs supplemented with COM or FCR and net economic benefits (54.3; 57.8; 17.1 and 1.96; 2.4) in lambs supplemented with COM and UMB-2, were CONT or supplemented with UMB-1, UMB-3 and UMB-4 respectively. Factors responsible for differences in feed intake, liveweight gain and economic benefits, are discussed.

21세기 종합상사의 신경영 전략에 관한 연구 -한(韓).일(日) 비교연구를 중심으로- (A Study on the New Management Strategies of the Trading Conglomerate in the 21st Century)

  • 최용민
    • 통상정보연구
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    • 제3권2호
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    • pp.261-280
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    • 2001
  • From the IMF(International Monetary fund) crisis, the management conditions of the trading company which run business in world market, has rapidly changed. In particular, the trading conglomerate's competitive power have declined. This study, addressing such changes, intend to analyze what factors are that have generated this changes in trading conglomerate's environment. The study specifically takes it into account that the differences between Korea trading company and Japan's. This research was confirmed by data and field survey in two country. The results of research are summarized as follow. The Korean trading company are inferior to the Japanese trading company in total volume(Korea: 24.1, Japan 100), the benefit volume(Korea: 8.7, Japan 100), the stability of turnover(Korea: 36.6, Japan 100), the network power in foreign country(Korea: 19.2, Japan 100), the power of e-business(Korea: 17.0, Japan 100). But the debt ratio of Korea company is significantly lower than that of Japan's(Korea: 160.4%, Japan 940.5%). In conclusion, providing that the Korean trading company want to be a world-class champion in trading field, they have to introduce the new management strategies which means the high-profit base trading, the long term investment and the internet business.

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건강보험 입원환자의 주관적 의료비 부담에 영향을 미치는 요인 (Factors Affecting Perceived Financial Burden of Medical Expenditures)

  • 최영순;이광옥;임은실
    • 간호행정학회지
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    • 제17권2호
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    • pp.147-157
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    • 2011
  • Purpose: This study was done to investigate factors affecting perceived financial burden of medical expenditures. Method: The participants were 2,024 inpatients who were enrolled in a survey on the benefit coverage rate of the National Health Insurance in 2006. The collected data were analyzed using t-test, ANOVA-test, Mann-Whitney-test, Kruskal-Wallis-test, Chi-square test and logistic regression. Results: The crucial factors for perceived financial burden were age, job, equivalence scale, ratio of annual family income vs medical expenditure, and private health insurance. Perceived financial burden was higher for people who were older, who were unemployed, whose medical expenditures were high compared to annual family income, whose index of family equalization was low and for those who had no private health insurance. Conclusion: The results of the study indicate a demand for system reform that will enable management of no-pay hospital bills in the National Health Insurance to decrease the medical expense of people in the low-income bracket.

ZnO films grown on GaN/sapphire substrates by pulsed laser deposition

  • Suh, Joo-Young;Song, Hoo-Young;Shin, Myoung-Jun;Park, Young-Jin;Kim, Eun-Kyu
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2010년도 제39회 하계학술대회 초록집
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    • pp.207-207
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    • 2010
  • Both ZnO and GaN have excellent physical properties in optoelectronic devices such as blue light emitting diode (LED), blue laser diode (LD), and ultra-violet (UV) detector. The ZnO/GaN heterostructure, which has a potential to achieve the cost efficient LED technology, has been fabricated by using radio frequency (RF) sputtering, pyrolysis, metal organic chemical vapor deposition (MOCVD), direct current (DC) arc plasmatron, and pulsed laser deposition (PLD) methods. Among them, the PLD system has a benefit to control the composition ratio of the grown film from the mixture target. A 500-nm-thick ZnO film was grown by PLD technique on c-plane GaN/sapphire substrates. The post annealing process was executed at some varied temperature between from $300^{\circ}C$ to $900^{\circ}C$. The morphology and crystal structural properties obtained by using atomic force microscope (AFM) and x-ray diffraction (XRD) showed that the crystal quality of ZnO thin films can be improved as increasing the annealing temperature. We will discuss the post-treatment effect on film quality (uniformity and reliability) of ZnO/GaN heterostructures.

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Application of DNA Microarray Technology to Molecular Microbial Ecology

  • Cho Jae-Chang
    • 한국미생물학회:학술대회논문집
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    • 한국미생물학회 2002년도 추계학술대회
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    • pp.22-26
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    • 2002
  • There are a number of ways in which environmental microbiology and microbial ecology will benefit from DNA micro array technology. These include community genome arrays, SSU rDNA arrays, environmental functional gene arrays, population biology arrays, and there are clearly more different applications of microarray technology that can be applied to relevant problems in environmental microbiology. Two types of the applications, bacterial identification chip and functional gene detection chip, will be presented. For the bacterial identification chip, a new approach employing random genome fragments that eliminates the disadvantages of traditional DNA-DNA hybridization is proposed to identify and type bacteria based on genomic DNA-DNA similarity. Bacterial genomes are fragmented randomly, and representative fragments are spotted on a glass slide and then hybridized to test genomes. Resulting hybridization profiles are used in statistical procedures to identify test strains. Second, the direct binding version of microarray with a different array design and hybridization scheme is proposed to quantify target genes in environmental samples. Reference DNA was employed to normalize variations in spot size and hybridization. The approach for designing quantitative microarrays and the inferred equation from this study provide a simple and convenient way to estimate the target gene concentration from the hybridization signal ratio.

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Multicasting Multiple Description Coding Using p-cycle Network Coding

  • Farzamnia, Ali;Syed-Yusof, Sharifah K.;Fisal, Norsheila
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제7권12호
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    • pp.3118-3134
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    • 2013
  • This paper deliberates for a multimedia transmission scheme combining multiple description coding (MDC) and network coding (NC). Our goal is to take advantage from the property of MDC to provide quantized and compressed independent and identically distributed (iid) descriptions and also from the benefit of network coding, which uses network resources efficiently to recover lost data in the network. Recently, p-cycle NC has been introduced to recover and protect any lost or distorted descriptions at the receiver part exactly without need of retransmission. So far, MDC have not been explored using this type of NC. Compressed and coded descriptions are transmitted through the network where p-cycle NC is applied. P-cycle based algorithm is proposed for single and multiple descriptions lost. Results show that in the fixed bit rate, the PSNR (Peak Signal to Noise Ratio) of our reconstructed image and also subjective evaluation is improved significantly compared to previous work which is averaging method joint with MDC in order to conceal lost descriptions.

Robust Cooperative Relay Beamforming Design for Security

  • Gong, Xiangwu;Dong, Feihong;Li, Hongjun;Shao, Wei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제9권11호
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    • pp.4483-4501
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    • 2015
  • In this paper, we investigate a security transmission scheme at the physical layer for cooperative wireless relay networks in the presence of a passive eavesdropper. While the security scheme has been previously investigated with perfect channel state information(CSI) in the presence of a passive eavesdropper, this paper focuses on researching the robust cooperative relay beamforming mechanism for wireless relay networks which makes use of artificial noise (AN) to confuse the eavesdropper and increase its uncertainty about the source message. The transmit power used for AN is maximized to degrade the signal-to-interference-plus-noise-ratio (SINR) level at the eavesdropper, while satisfying the individual power constraint of each relay node and worst-case SINR constraint at the desired receiver under a bounded spherical region for the norm of the CSI error vector from the relays to the destination. Cooperative beamforming weight vector in the security scheme can be obtained by using S-Procedure and rank relaxation techniques. The benefit of the proposed scheme is showed in simulation results.

2-모드 기계유압식 무단변속기의 성능 및 전달효율해석 (Performance and Transmission Efficiency Analysis of 2-Mode Hydro Mechanical Transmission)

  • 정규홍;김형의;김종기
    • 한국자동차공학회논문집
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    • 제13권1호
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    • pp.90-98
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    • 2005
  • HMT is a type of continuously variable transmission which has split power flow path characteristics with gear train and hydro static unit. The benefit of improved fuel economy and high power capacity enables it to be a promising application fur large vehicles. This paper presents the analysis results including velocity, static torque, transmission efficiency and dynamic model of the HMT that is developed for city buses. The speeds or gear shafts, the static clutch torque and split power ratio for each mode are detailed here. From the analysis of HMT transmission efficiency considering the power loss in meshed gear and hydraulic unit, we can conclude that minimization of hydraulic power is necessary for improved fuel economy design. Also, the dynamic simulation result for mode shift characteristics shows that little shift shock is observed because of the synchronized rotation speed in clutch.