• 약학회지
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• 제25권2호
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• pp.49-55
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• 1981

To elucidate the effect of ginseng saponin on adrenaline-induced hyperglycemia and hyperlipidemia, ginseng saponin was administered before and after administration of adrenaline, and concentration of glucose, triglyceride(TG), and free fatty acid (FFA) as well as lipase activity in plasma was determined. 1) Glucose concentration was slightly increased by administration of ginseng saponin at 1 hour before and 10 minutes after adrenaline administration, but decreased by administration of ginseng saponin at 7 and 4 hours before adrenaline administration. TG and FFA concentration was also greatly inhibited by administration of ginseng saponin in advance. 2) When gineseng saponin 3, 10, 30mg/kg were administered 7 hours before adrenaline administration, glucose and TG concentration as well as lipase activity were inhibited in proportion to the dose of ginseng saponin, but FFA concentration was slightly inhibited. 3) It was suggested that protopanaxatriol group have potentiating effect on adrenaline induced hyperglycemia but protopanaxadiol group have inhibitory effect. And ginseng saponin seems to have strong inhibitory action on TG mobilization into blood and stimulatory effect on esterification of FFA in liver and adipose tissue.

• IEIE Transactions on Smart Processing and Computing
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• 제3권2호
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• pp.65-73
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• 2014

An overall responding security-centered framework is necessary required for infringement accidents, failures, and cyber threats. On the other hand, the correspondence structures of existing administrative, technical, physical security have weakness in a system responding to complex attacks because each step is performed independently. This study will recognize all internal and external users as a potentially threatening element. To perform connectivity analysis regarding an action, an intelligent convergence security framework and road map is suggested. A suggested convergence security framework was constructed to be independent of an automatic framework, such as the conventional single solution for the priority defense system of APT of the latest attack type, which makes continuous reputational attacks to achieve its goals. This study suggested the next generation convergence security framework to have preemptive responses, possibly against an APT attack, consisting of the following five hierarchical layers: domain security, domain connection, action visibility, action control, and convergence correspondence. In the domain, the connection layer suggests a security instruction and direction in the domains of administrative, physical and technical security. The domain security layer has consistency of status information among the security domain. A visibility layer of an intelligent attack action consists of data gathering, comparison and decision cycle. The action control layer is a layer that controls the visibility action. Finally, the convergence corresponding layer suggests a corresponding system of before and after an APT attack. The administrative security domain had a security design based on organization, rule, process, and paper information. The physical security domain is designed to separate into a control layer and facility according to the threats of the control impossible and control possible. Each domain action executes visible and control steps, and is designed to have flexibility regarding security environmental changes. In this study, the framework to address an APT attack and load map will be used as an infrastructure corresponding to the next generation security.

• 패션비즈니스
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• 제7권4호
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• pp.26-42
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• 2003

On-line clothes sale are on the increase, and the returns(for replacements or refunds) of the clothes are also increasing. Many studies on off-line consumers' complaints were made before, but few studies on the returns of clothes sold on-line have been made. From this viewpoint, this study was conducted to know what effect returns of clothes sold on-line have on their brands. Therefore, this study was first focused on the factors affecting complaint acts(return intention or return acts) such as lack of information and recognition of product, delivery errors and product defects concerning on-line sales, and second investigated the changes of buyers' attitude toward the brand following the their acts of returning the buyers, and third looked into the changes of on-line buyers' attitude toward the brand. The study is carried out by subdividing the objects of the study into return action(replacement, refundment) and purchasers who experienced return intention. Such experience is demonstratively analyzed to find how it has affected the attitude toward the brand. The study comes up with the following outcomes. First, the effect factor causing complaint action(return action, return intention) on-line is shown as the lack of the information and recognition of the product. Second, it is revealed that the effect factor causing complaint(return action, return intention) does not lie in an error in delivery or a defect of a product. Third, the positive response of a brand to a return action does not raise the repurchasing intention and positive attitude of purchasers who experienced returning a product, but lowers their private complaint action intention. Fourth, the repurchase intention of purchasers who experienced return intention for the brand is lowered, but their negative attitude and private complaint action intention is not raised.

• 융합정보논문지
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• 제10권8호
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• pp.229-238
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• 2020

본 연구는 점진적 관찰감소 동작 관찰훈련이 만성기 뇌졸중 환자의 상지 기능과 일상생활 활동에 미치는 영향을 알아보고자 실시하였다. 만성기 뇌졸중 환자를 대상으로 점진적 관찰감소 동작 관찰훈련을 하는 실험군 4명과 기존의 동작 관찰 훈련을 받는 3명의 대조군으로 구분하여, 주 6회, 회당 30분씩, 총 2주간 실시하였다. 상지 기능 평가는 상자와 나무토막 검사(BBT)와 푸글 마이어 상지 운동기능평가 (FMA)를, 일상생활 활동 수행능력 평가는 한글판 수정바델지수(K-MBI)와 운동 활동 지표 (MAL)를 사용하였다. 그룹 별 중재 전·후 차이의 비교 결과와 두 그룹 간의 비교 결과는 BBT, FMA, K-MBI, MAL에서 통계적으로 유의한 차이를 보이진 않았으나, 실험군이 대조군에 비해 평균 점수 측면에서 더 큰 차이가 나타났다. 결과적으로 점진적 관찰감소 동작 관찰훈련은 기존의 동작관찰훈련 보다 더욱 긍정적인 영향을 끼칠 수 있음을 확인할 수 있었다.

• Biomolecules & Therapeutics
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• 제9권2호
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• pp.96-103
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• 2001

These studies were investigated about influence of SKP 450, a $K^{+}$ channel opener, on the pressor actions induced by norepinephrine, angiotensin II and carotid artery occlusion in rats. Before these studies, effect of SKP 450 itself on blood pressure was examinated. SKP 450 produced the depressor action in proportionaly to dose of 0.3, 1.0 and 3.0 $\mu$g/kg given intravenously and this depressor action was weakened by pretreatment of glibenclamide, a $K^{+}$ channel blocker. The pressor action induced by norepinephrine, an alpha-adrenergic agonist, was blocked 1 hr after administation of SKP 450 in a dose of 3.0 $\mu\textrm{g}$/kg, i.v. and directly after in a dose of 6.0 $\mu\textrm{g}$/kg, i.v.. The pressor action induced by angiotensin II was blocked immediatly after treatment of SKP 450 in a dose of 3.0 $\mu\textrm{g}$/kg, i.v.. The pressor action caused by carotid artery occlusion was not affected by SKP 450 of 3.0 $\mu\textrm{g}$/kg, i.v., whereas markedly blocked by SKP 450 of 6.0 $\mu\textrm{g}$/㎦, i.v.. The potentiated-pressor actions of norepinephrine and angiotensin II by pretreatment of chlorisondamine, a autonomic ganglionic blocking agent, were also blocked by administration of SKP 450 in a dose of 6.0 $\mu\textrm{g}$/kg, i.v.. The weakened-pressor action of carotid artery occlusion by pretreatment of chlorisondamine was more weakened by SKP 450 6.0 $\mu\textrm{g}$/kg, i.v.. The results suggest that hyperpolarization formed through $K^{+}$ channel opening in cell membrane inhibits the pressor action induced norepinephrine ; angiotensin II ; and carotid artery occlusion.usion.

• 간호행정학회지
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• 제18권4호
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• pp.442-451
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• 2012

Purpose: The purpose of this study was to identify effects of action learning approaches on learning outcomes of students taking nursing management courses. Methods: The questionnaire surveys were completed between March 2011 and June 2012 by 109 undergraduate seniors in the nursing department of C University. Survey data were obtained 3 times: before, in and after the study of nursing management. The course consisted of lectures and clinical practices. Learning outcomes were measured through problem solving skills, team efficacy, and class satisfaction. Collected data were analyzed using repeated measures ANOVA with the SPSS 20.0 program Results: Scores for problem solving skills (F=13.67, p<.001) and team efficacy (F=4.49, p=.012) showed statistically significant increases after the course. The scores also increased significantly after the lectures for 5 of 9 problem solving skill subscales: analysis skill, divergent thinking, decision making, assessment, feedback, and after the clinical practices for 2 subscales: divergent thinking, and execution and risk taking. Class satisfaction score also increased after both the lectures and the clinical practices. Conclusion: The findings from this study suggest that an action learning approaches for nursing management courses would be a useful teaching and learning method to achieve learning outcomes.

• The Journal of Korean Physical Therapy
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• 제34권3호
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• pp.98-103
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• 2022

Purpose: New therapeutic approaches have emerged to improve gait ability in patients with brain damage, such as action observation learning (AOT), auditory cueing, motor imagery etc. We attempted to investigate the effects of AOT with auditory cueing (AOTAC) on gait function in patients with stroke. Methods: The eighteen stroke patients with a unilateral hemiparesis were randomly divided into three groups; the AOTAC, AOT, and control groups. The AOTAC group (n=8) received training via observing a video that showed normal gait with sound of footsteps as an auditory cue; the AOT group (n=6) receive action observation without auditory stimulation; the control group (n=5) observed the landscape video image. Intervention time of three groups was 30 minutes per day, five times a week, for four weeks. Gait parameters, such as cadence, velocity, stride length, stance phase, and swing phase were collected in all patients before and after each training session. Results: Significant differences were observed among the three groups with respect to the parameters, such as cadence, velocity, stride length, and stance/swing phase. Post-hoc analysis indicated that the AOTAC group had a greater significant change in all of parameters, compared with the AOT and control groups. Conclusion: Our findings suggest that AOTAC may be an effective therapeutic approach to improve gait symmetry and function in patients with stroke. We believe that this effect is attributable to the change of cortical excitability on motor related to cortical areas.

• 대한지역사회작업치료학회지
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• 제3권1호
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• pp.55-66
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• 2013

목적 : 본 연구는 과제지향적 동작관찰훈련이 뇌졸중 환자의 환측 상지기민성과 일상생활활동에 미치는 영향을 알아보고자 하였다. 연구방법 : 15명의 뇌졸중 편마비 환자를 선정하여 단일집단 사전사후 설계를 사용하였다. 대상자는 동영상을 통하여 과제지향적 동작수행을 관찰한 후 동작을 반복적으로 모방 연습하였다. 훈련은 주 3회, 회당 20~30분, 3주간 실시하였다. 환측 상지기민성에 대해 MFT, 10초 검사, 박스와 나무상자 검사를 시행하였고, 일상생활활동은 MBI, MAL을 수행하였다. 전, 후 비교는 윌콕슨 부호순위검정를 사용하였다. 결과 : 훈련 후, 대상자의 환측 상지기민성은 훈련 전에 비해 유의한 차이를 보였고, 일상생활활동 또한 훈련 전과 훈련 후에 유의미한 증진을 보였다. 결론 : 과제지향적 과제를 적용한 동작관찰훈련은 뇌졸중 환자의 환측 상지기민성과 일상생활활동에 긍정적인 효과를 보였다. 따라서 동작관찰훈련을 작업치료 중재 유형의 한 전략으로 제안하고자 한다.

• Restorative Dentistry and Endodontics
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• 제17권1호
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• pp.10-21
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• 1992

The purpose of this study was to investigate the analgesic effect of eugenol, capsaicin and demethoxy-NE. Young adult cats, weighing 2.0 to 3.0kg, were used. Each animal was anesthetized (${\alpha}$-chloralose 60mg per kg body weight) and divided into four groups; control, eugenol, capsaicin and demethoxy-NE group. The anterior digastric muscles were exposed and a pair of electrodes was inserted to record the electromyograms. To expose the pulp, each canine teeth was prepared with a low speed bur under cooling and used for recording anterior digastric muscular EMGs evoked by noxious stimulation of dental pulp. To observe effects on jaw opening reflex, inferior alveolar nerve of both sides were exposed for drug application and wire electrodes were inserted in anterior digstric muscle for recording the EMGs. To observe effects on action potential, saphenous nerves of both sides were exposed and three tissue pools were made from surrounding tissue. The most distal pool was used for applying stimulation, the most proximal one for recording of action potential, and the other one for drug application. One side of inferior alveolar nerve and saphenous nerve were used for eugenol, capsaicin, or demethoxy-NE application, the other side of nerve for control experiments(only vehicle application). Anterior digastric muscular EMGs evoked by noxious stimulation of dental pulp were recorded before drug application, immediate after drug application, at 60 and 120 minutes, and 5 days after drug application. Action potentials were recorded before drug application, immediate after 30 minutes drug application, at 30, 60 and 120 minutes after drug had been washed out. The results were as follows; 1. Eugenol had a continuous blocking effect on the anterior digastric muscular EMGs evoked by noxious pulp stimulation and after 5 days, showed completely blocking effect. 2. After 5 days, demethoxy-NE applied to dental pulp had a considerable blocking effect on the jaw opening retlex evoked by noxious stimulation but capsaicin had no significant effect. 3. After 5 days, eugenol group showed the strongest blocking effect among the all experimental groups on the jaw opening reflex evoked by noxious stimulation of dental pulp and capsaicin group showed the weakest blocking effect. 4. Eugenol had a completely blocking effect on the action potential conductivity of peripheral nerve. Capsaicin and demethoxy-NE had the blocking effect on the action potential conductivity of ${\alpha}$-and C-nerve fibers. 5. Capsaicin, demethoxy-NE and eugenol applied to inferior alveolar nerve surppressed the jaw opening reflex evoked by noxious stimulation of dental pulp.

• 한국전문물리치료학회지
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• 제26권2호
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• pp.8-15
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• 2019

Background: Improvement of the lumbo-pelvic stability can reduce the compensatory action of the erector spinae (ES) during prone hip extension (PHE). Furthermore, the application of abdominal drawing-in (ADI) maneuver increases the action of gluteus maximus (GM) and decreases the action of ES during PHE by improving the lumbo-pelvic stability. However, the post-ADI exercise effects on PHE, not the real-time application of ADI maneuver, has not been studied. Objects: This study is aimed at investigating the post-ADI exercise effects on the muscle activities of GM and ES during PHE. Methods: A total of 24 female adults participated in the study, and they were divided into two groups: Those with normal abdominal muscles ($n_1=12$) and those with weak abdominal muscles (WA) ($n_2=12$). Before the intervention, the subjects' GM and ES muscle activities during PHE were measured. Subsequently, the two groups were asked to perform the ADI exercise for 10 minutes. After the ADI exercise, the GM and ES activities were equally measured during PHE. Results: The comparison result of the ES muscle activities before intervention shows a significant difference between the two groups (p<.05); the WA group showed higher muscle activities than the normal group. For the within-group comparison, the muscle activities of the ES in the WA group significantly decreased after the ADI exercise (p<.05). For the GM muscle activity, no significant difference was observed in all comparisons (p>.05). For the changes in muscle activities before and after the ADI exercise, a significant difference exists between the two groups only for the changes in ES activities (p<.05); WA group exhibits higher changes than the normal group. By contrast, no significant difference exists between the two groups for the changes in GM activities (p>.05). Conclusion: After the ADI exercise, the compensatory action of ES in the female adults with WC is implied to decrease during PHE.