• Journal of Korean Neurosurgical Society
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• 제50권5호
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• pp.403-408
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• 2011

Objective : Contrary to some clinical belief, there were quite a few studies regarding animal models of intracerebral hemorrhage (ICH) $in$ $vivo$ suggesting that prior use of statins may improve outcome after ICH. This study reports the effect of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG CoA) reductase inhibitor, simvastatin given before experimental ICH. Methods : Fifty-one rats were subjected to collagenase-induced ICH, subdivided in 3 groups according to simvastatin treatment modality, and behavioral tests were done. Hematoma volume, brain water content and hemispheric atrophy were analyzed. Immunohistochemical staining for microglia (OX-42) and endothelial nitric oxide synthase (eNOS) was performed and caspase-3 activity was also measured. Results : Pre-simvastatin therapy decreased inflammatory reaction and perihematomal cell death, but resulted in no significant reduction of brain edema and no eNOS expression in the perihematomal region. Finally, prior use of simvastatin showed less significant improvement of neurological outcome after experimental ICH when compared to post-simvastatin therapy. Conclusion : The present study suggests that statins therapy after ICH improves neurological outcome, but prior use of statins before ICH might provide only histological improvement, providing no significant impact on neurological outcome against ICH.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2021년도 가을 학술논문 발표대회
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• pp.242-243
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• 2021

The concrete inside the steel tube of CFT columns enables them to have great strength and ductility. CFT columns are also excellent in fire-resistance because explosive heat upon a fire can be contained in the tube by the concrete debris. However, the studies to evaluate the residual strength of CFT columns after a fire have not been conducted enough. The studies to evaluate the residual strength of CFT columns after a fire are indispensable because it is the barometer of the damage of composite columns caused by a fire and the degree of repair and reinforcement work for the columns after a fire. Accordingly, the purpose of this study is to evaluate the deterioration of load capacity and structural behavior of square CFT columns with the same shapes and boundary conditions before and after a fire. The study also evaluates the influential factors of the CFT columns reinforced to secure the residual strength after a fire.

• Journal of Nutrition and Health
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• 제30권10호
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• pp.1195-1202
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• 1997

Iodine-rich seaweed soup has been traditionally supplied to postpartum women in Korea. This dietary habit might introduce over-intake of iodine above the recommended requirements, and might provoke postpartum thyroid dysfunction. Although the response to excess iodine intake is highly variable, goiter, hyperthyroidism, hypothyroidism, and thyroiditis could follow the daily intake of 1,500$\mu\textrm{g}$ of iodine. A few studies are available concerning iodine toxicity in Korea. The purpose of this study was to investigate the relationships between the dietary intake of iodine and thyroid function change as well as the incidence of postpartum thyroiditis. One hundred and thirty-seven postpartum women who had experienced normal deliveries were studied. Dietary intake of iodine and excretion concentration of iodine in breast milk and maternal urine were measured . Serum T$_3$, T$_4$, TSH, anti-thyroglobulin antibody, and anti-microsomal antibody were anlayzed 1 week before delivery and 1, 6, 12, and24 weeks after delivery. Iodine intake was analyzed by one-to-one interviews using 24-hr recall and a food frequncy questionnaire. The result showed that the intake of dietary iodine before delivery and 1 and24 weeks after delivery were 483$\mu\textrm{g}$/day, 3367$\mu\textrm{g}$/day, and 1069$\mu\textrm{g}$/day, respectively. The concentration of iodine in urine at the first week after delivery was 63$\mu\textrm{g}$/dL, and 23.9$\mu\textrm{g}$/dL in breast milk . The levels of serum T$_3$ and T$_4$ before delivery were 2.01ng/mL and 11.49$\mu\textrm{g}$U/dL, respectively, showing that the levels were gradually dropping to normal values after delivery. Positive serum anti-thyroglobulin antibody and anti-microsomal antibody appeared in 3 cases. After a 24 week follow-up period , 6 women(10.3%) experienced cases of postpartum thyroiditis, 5 of which were cases of hyperthyroidism and one of which was a case of hypothyroidism. These figures of postpartum thyroiditis are similar to those of other countries.

• 음성과학
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• 제1권
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• pp.237-259
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• 1997

Cleft Palate speech appears to have hyper/hyponasality with velopharyngeal insufficiency and articulation disorders. Previous studies on Cleft Palate speech have shown that speech tends to have lower airflow and air pressure. To examine the aerodynamic characteristics of Cleft Palate speech, Aerophone II Voice function Analyzer was used. We measured sound pressure level, airflow, air pressure and glottal power. Three Cleft Palate adults and five normal adults participated in this experiment. The test words are composed of: (1) the sustained vowel /o/ (2) /CiCi/, where C is one of three different stop consonants in Korean (3) /bimi/. Subjects were asked to produce /bimi/ five times without opening their lips. All the data was statistically tested by t-test for Cleft Palate patients before operation groups and control groups and paired t-test for Cleft Palate patients before and after operation groups. The results were as follow: (1) Cleft Palate patients generally speak with incomplete oral closure and lower oral air pressure. As a result, the SPL of Cleft Palate before operation is 3 dB lower than control groups. (2) Airflow of Cleft Palate in phonation and articulation is lower than that of control groups. However, it increased after operation. Lung volume and mean airflow in phonation are significantly increased (p<0.05). (3) Although velopharyngeal function (velar opening rate) of Cleft Palate is poor in comparison with control groups, it was recovered after operation. In this event maximum flow rate and mean airflow rate are significantly increased (p<0.05). (4) Air pressure of Cleft Palate in speech is lower than that of control groups. In general, the air pressure of Cleft Palate increased after operation. In this event air pressure of glottalized consonant is significantly increased (p<0.04). (5) Glottal Power(mean power, mean efficient and mean resistant) of Cleft Palate patients is lower than that of control groups. But mean efficient and mean resistant of Cleft Palate patients increased significantly (p<0.05) after operation.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.500-507
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• 2022

COVID-19 pandemic forces college education to be rapidly switched from face-to-face education into remote education. Two inconsistent findings exist in previous study about remote learning. First, studies before COVID-19 pandemic found remote learning is an effective method, which provided students with higher achievement and improved their work-life balance. However, studies showed remote learning during COVID-19 pandemic is not as effective as expected because of technical issues, lack of motivations and even mental health issues. Second, findings from studies about remote learning impacts on workload and productivity during COVID-19 are also inconsistent. Therefore, this study aims to quantitatively measure college students' workload and productivity during COVID-19 of different types of tasks to provide a comprehensive and latest evaluation on remote learning. The findings of this study show remote learning slightly increases college students' total listening and speaking tasks workload, total reading and writing tasks workload. Furthermore, phone call, in-person meeting, online meeting and email workload increase significantly in remote learning. However, productivity for both listening and speaking, reading and writing tasks decreases after remote learning but no significant changes of productivity are found.

• 한국지역사회생활과학회지
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• 제17권3호
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• pp.109-121
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• 2006

This study examines the relationship between mother's stress and cortisol level during late pregnancy and how it changes into postpartum periods. Thirty one families were recruited from Daejeon and Incheon in South Korea. The major findings were as follows: (1) The level of mothers' cortisol followed the typical diurnal pattern of decline throughout the day. Further longitudinal analysis revealed that the level of Korean mothers' cortisol steadily lowered from the 8th prenatal month to the 6th postnatal month. (2) During pregnancy, mothers reported to experience changes in physical activities, daily routines, eating habits, types or amount of social activities and sleeping habits. Among these they were stressed the most by changes in physical activities and social activities. (3) The results of postpartum depression tests conducted at two months after giving birth showed mothers at this time were mostly stressed from difficulty sleeping and unnecessary self criticism. (4) The level of psycho social stress in mothers at six months after giving birth was mainly on social roles and the questions about self reliance marked the highest points. (5) Overall, there was a tendency for the level of maternal stress to decrease definitely from before and after the delivery and even though the level of stress was steadily decreasing up to 6th postpartum month it was not as sharp as those of before and after the birth of the babies. The level of cortisol analysis also showed the same obvious tendency.

• Journal of Oral Medicine and Pain
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• 제42권3호
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• pp.62-71
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• 2017

Purpose: The purpose of this study was to examine the rate of salivation before and after olfactory stimulation using BPO (black pepper oil) and then, to collect basic data for screening the possibility of introducing olfactory stimulus to prevent and improve dry mouth. Methods: The subjects in this study were 60 college students in Jeon-Nam province. The subjects were randomly divided into 3 groups; the BPO group (n=20), the lavender oil (LVO) group (n=20), and the distilled water (DW) group (n=20). The amount of whole saliva before and after olfactory stimulation was measured 14 times for a 4-week period. Results: In the BPO and LVO groups, the amount of whole saliva increased after the olfactory stimulation and it was most prominent in the BPO group (p<0.05). The difference of whole salivation was higher in the BPO group (p<0.05) and there was no significant difference in the salivary flow rate in the DW group. After 14 times of measurement for 4 weeks, the BPO and LVO groups showed an increase in salivary rate at an early stage compared without stimulation (p<0.05), but there was no significant difference between the 2 groups in the middle. Since the twelfth measurement, whole saliva secretion increased and maintained the elevated level (p<0.05). Conclusions: The olfactory stimulation using BPO may contribute to stimulating salivation. Further studies are needed for subjects with dry mouth symptoms. In the future, qualitative and quantitative studies should be conducted for people who complains about oral dryness.

• 대한한방체열의학회지
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• 제4권1호
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• pp.45-53
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• 2005

Objectives; Hapkok(L14) and Taechung(Liv3) are acupuncture points located on both sides of each foot and hand of the human body. These two points are called sakwan points. Matching these acupuncture points have a significant reason in points of not only regulating the circulation of Yin-Yang as a source point of each meridian, but also playing a basic role of twelve meridian by controling circulation of ki and blood in the whole body. There are already related documents and studies on stimulating sakwan points. Since those papers mostly studied on either hapkok or taechung, we came to have a doubt of stimulating the two point at the same time when an inbalance of Yin-Yang and ki-blood appears. Accordingly, we got to investigate how thermogram of body changes after applying an acupuncture on sakwan points. Our study is as follows ; Methods; Our study was performed on 30 normal cases(M:F=17:13) with no past history to observe the effects of the acupuncture. We measured temperature of abdomen and the back of both hands by D.I.T.I(Digital Infrared Thermographic Imaging) before and after acupuncture on sakwan points. Results and Conclusion; The thermographic change on abdomen was $0.51{\pm}0.71^{\circ}C$. Temperature of abdomen after acupuncture was higher than before acupuncture with high validity(p <0.01). And the thermographic changes on the back of both hands were right hand $0.54{\pm}1.17^{\circ}C$, left hand $0.56{\pm}1.28^{\circ}C$. Temperature on the back of both hands after acupuncture was higher than before acupuncture, but the difference between them had little validity(p <0.01) In addition, we found that it doesn't necessarily follow that the thermographic changes on abdomen and back of both hands after acupuncture on sakwan points happen concurrently.

• Journal of Acupuncture Research
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• 제20권1호
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• pp.51-60
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• 2003

Objective: Hapkok(L14) and Taechung(Liv3) are acupuncture points located on both sides of each foot and hand of the human body. These two points are called sakwan points. Matching these acupuncture points have a significant reason in pints of not only regulating the circulation of Yin-Yang as a source point of each meridian, but also playing a basic role of twelve meridian by controlling circulation of ki and blood in the whole body. There are already related documents and studies on stimulating sakwan points. Since those papers mostly studied on either hapkook or taechung, we came to have a doubt of stimulation the two point at the same time when an unbalance of Yin-Yang and ki-blood appears. Accordingly, we got to investigate how thermogram of body changes after applying an acupuncture on sakwan points. Our study is as follows ; Method : Our study was performed on 30 normal cases(M:F=17:13) with no past history to observe the effects of the acupuncture. We measured temperature of abdomen and the back of both hands by D.I.T.I(Digital infrared Thermographic Imaging) before and after acupuncture on sakwan points. Results and Conclusions: The thermographic change on abdomen was $0.51{\pm}0.71^{\circ}C$. Temperature of abdomen after acupuncture was higher than before acupuncture with high validity(p<0.01). And the thermographic changes on the back of both hands were right hand $0.54{\pm}1.17^{\circ}C$, left hand $0.56{\pm}1.28^{\circ}C$. Temperature on the back of both hands after acupuncture was higher than before acupuncture, but the difference between them had little validity(p<0.01). In addition, we found that it doesn't necessarily follow that the thermographic changes on abdomen and back of both hands after acupuncture on sakwan points happen concurrently.

• KDI Journal of Economic Policy
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• 제30권2호
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• pp.27-59
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• 2008

본 연구에서는 외부금융이 기업 성장에 영향을 미치는 다양한 경로에 대해 살펴보고, 1997년 외환위기를 전후하여 외부금융과 기업의 개별 성장요인 간 관계가 어떻게 변화하였는지를 우리나라 제조업 기업의 재무자료를 이용하여 실증분석하였다. 주요 분석결과는 다음과 같다. 첫째, 외부금융의 증가는 기업의 고정자본스톡 증가를 통해 기업 성장에 기여하는 것으로 분석되었다. 그러나 이러한 자본축적 촉진 효과는 위기이전에 비해 97년 이후 상대적으로 약화된 것으로 나타난다. 둘째, 외부금융이 기업의 총요소생산성을 높이는 효과는 위기 이전과 이후에 모두 미약한 것으로 분석되었다. 셋째, 외부금융의 정보비대칭성 완화 효과 및 기업 구조조정 촉진 효과 또한 위기 이후에도 여전히 미약한 것으로 분석되었다. 이처럼 위기 이후 금융 구조조정의 진전에도 불구하고 외부금융이 기업성장에 미치는 긍정적인 영향이 여전히 미진한 배경으로는, 기업투자의 전반적인 침체, 우량기업의 외부자금의존도 하락 등의 요인도 일부 작용하고 있는 것으로 보인다. 본 분석결과는 금융 부문이 우리 경제의 지속적인 성장을 보다 효율적으로 뒷받침하기 위해서는 재원배분, 모니터링, 구조조정 기능 등이 더욱 강화될 필요가 있음을 시사한다.