• Geomechanics and Engineering
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• 제21권1호
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• pp.23-33
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• 2020

An advancing cutting roof for gob-side entry retaining with no-pillar mining under specific geological conditions is more conducive to the safe and efficient production in a coalmine. This method is being promoted for use in a large number of coalmines because it has many advantages compared to the retaining method with an artificial filling wall as the gateway side filling body. In order to observe the inner structure of the gateway cutting roof and understand its stability mechanism, an equivalent material simulation experiment for a coalmine with complex geological conditions was carried out in this study. The results show that a "self-stabilization bearing structure" equilibrium model was found after the cutting roof caving when the cut line deviation angle was unequal to zero and the cut height was greater than the mining height, and the caving roof rock was hard without damage. The model showed that its stability was mainly controlled by two key blocks. Furthermore, in order to determine the optimal parameters of the cut height and the cut line deviation angle for the cutting roof of the retaining gateway, an in-depth analysis with theoretical mechanics and mine rock mechanics of the model was performed, and the relationship between the roof balance control force and the cut height and cut line deviation angle was solved. It was found that the selection of the values of the cut height and the cut line deviation angle had to conform to a certain principle that it should not only utilize the support force provided by the coal wall and the contact surface of the two key blocks but also prevent the failure of the coal wall and the contact surface.

• 한방재활의학과학회지
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• 제31권1호
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• pp.17-32
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• 2021

Objectives The present study was designed to find out the therapeutic effects and possible underlying mechanism of Buja-tang, a herbal complex formula on experimental monosodium iodoacetate (MIA)-induced osteoarthritis. Methods Osteoarthritis models were created via intra-joint injection of MIA (50 μL with 80 mg/mL) in rats. Rats were divided into five groups and each group consisted of seven. Normal group was not injected MIA and did a normal diet. Control group injected MIA and received distilled water. Indo injected MIA and oral administration of 5 mg/kg of indomethacin. BJTL injected MIA and oral administration of 100 mg/kg of Buja-tang. BJTH injected MIA and oral administration of 200 mg/kg of Buja-tang. We analyzed weight-bearing ability of hind paws, oxidative stress related factor, antioxidant protein, inflammatory protein, inflammatory messenger and cytokine in joint tissue. Pathological observation of knee cartilage tissue structures was also performed with hematoxylin & eosin and safranin-O chromosomes. Results Weight-bearing ability of hind paws showed a tendency to reduce pain. The incidence of nicotinamide adenine dinucleotide phosphate oxidase and p22phox in articular tissue was significantly reduced, and the incidence of nuclear factor-erythroid 2-related factor 2 and heme oxygenase-1 and superoxide dismutases was significantly increased. The incidence of phosphorylated inhibitor of κBα, nuclear factor-kappa B p65, inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor alpha, interleukin (IL)-6, and IL-1β decreased significantly. In pathological observation, cartilage tissue damaged by MIAs in biopsy has significantly recovered from Buja-tang administration. Conclusions Buja-tang has anti-inflammation, antioxidation and pain relief effects. So this is thought to inhibit the progress of osteoarthritis in rat caused by the MIA.

• Steel and Composite Structures
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• 제21권2호
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• pp.267-287
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• 2016

The seismic performance of the ordinary steel reinforced concrete (SRC) columns has no significant improvement compared to the reinforced concrete (RC) columns mainly because I, H or core cross-shaped steel cannot provide sufficient confinement for core concrete. Two improved SRC columns by constructing with new-type shaped steel were put forward on this background, and they were named as enlarging cross-shaped steel and diagonal cross-shaped steel for short. The seismic behavior and carrying capacity of new-type SRC columns have been researched theoretically and experimentally, while the shear behavior remains unclear when the new-type columns are joined onto SRC beams. This paper presents an experimental study to investigate the shear capacity of new-type SRC joints. For this purpose, four new-type and one ordinary SRC joints under low reversed cyclic loading were tested, and the failure patterns, load-displacement hysteretic curves, joint shear deformation and steel strain were also observed. The ultimate shear force of joint specimens was calculated according to the beam-end counterforce, and effects of steel shape, load angel and structural measures on shear capacity of joints were analyzed. The test results indicate that: (1) the new-type SRC joints display shear failure pattern and has higher shear capacity than the ordinary one; (2) the oblique specimens have good bearing capacity if designed reasonably; and (3) the two proposed construction measures have little effect on the shear capacity of SRC joints embedded with diagonal cross-shaped steel. Based on the mechanism observed from the test, the formulas for calculating ultimate shear capacity considering the main factors (steel web, stirrup and axial compression ratio) were derived, and the calculated results agreed well with the experimental and simulated data.

• Structural Engineering and Mechanics
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• 제47권4호
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• pp.575-598
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• 2013

The study presents the results of an experimental program concerning the shear force transfer between reinforced concrete (RC) jackets and existing columns with damages. In order to investigate the effectiveness of the repair method applied and the contribution of each shear transfer mechanism of the interface. It includes 22 concrete columns (core) (of 24,37MPa concrete strength) with square section (150mm side, 500 mm height and scale 1:2). Ten columns had initial construction damages and twelve were subjected to initial axial load. Sixteen columns have full jacketing at all four faces with 80mm thickness (of 31,7MPa concrete strength) and contain longitudinal bars (of 500MPa nominal strength) and closed stirrups spaced at 25mm, 50mm or 100mm (of 220MPa nominal strength). Fourteen of them contain dowels at the interface between old and new concrete. All columns were subjected to repeated (pseudo-seismic) axial compression with increasing deformation cycles up to failure with or without jacketing. Two load patterns were selected to examine the difference of the behavior of columns. The effects of the initial damages, of the reinforcement of the interface (dowels) and of the confinement generated by the stirrups are investigated through axial- deformation (slip) diagrams and the energy absorbed diagrams. The results indicate that the initial damages affect the total behavior of the column and the capacity of the interface to shear mechanisms and to slip: a) the maximum bearing load of old column is decreased affecting at the same time the loading capacity of the jacketed element, b) suitable repair of initially damaged specimens increases the capacity of the jacketed column to transfer load through the interface.

• 한국지반공학회논문집
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• 제30권1호
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• pp.103-116
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• 2014

본 논문에서는 석션파일의 하중지지력 및 압밀 거동에 대한 수치해석 내용을 다루었다. 수치해석에서는 파일-지반 간 인터페이스 거동이 고려된 3차원 모델을 적용하여 석션파일의 길이 대 직경 비, 하중 형태(수직하중, 수평 및 조합하중)를 변화시키며 해석을 수행하고 그 결과를 토대로 수직 및 수평지지력 거동 특성을 고찰하였다. 아울러 임의의 수직하중이 작용하는 조건에 대해 응력-간극수압 연계해석을 수행하여 석션파일의 하중재하 후 압밀거동을 고찰하였다. 해석 결과 석션파일의 지지력은 석션파일과 지반간의 상호작용 모델링 여부에 따라 큰 차이가 발생하는 것으로 검토되어 인터페이스 모델링의 중요성이 부각되었으며 산정된 하중지지력 결과를 토대로 제시된 조합하중에 대한 파괴포락선을 제시하였다. 아울러 응력-간극수압 연계해석에 근거한 압밀해석 결과를 분석한 결과 석션파일은 주면마찰이 주 하중지지 구조인 관계로 수직하중 재하시 과잉간극수압 발생량 및 압밀침하량은 미미한 것으로 검토되었다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.956-959
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• 2004

Recently the monitoring system of tool setting in high speed precision machining center is required for manufacturing products that have highly complex and small shape, high precision and high function. It is very important to reduce time to setup tool in order to improve the machining precision and the productivity and to protect the breakage of cutting tool as the shape of product is smaller and more complex. Generally, the combination of errors that geometrical clamping error of fixing tool at the spindle of machining tool and the asynchronized error of driving mechanism causes that the run-out of tool reaches to 3$^{\sim}$20 times of the thickness of cutting chip. And also the run-out is occurred by the misalignment between axis of tool shank and axis of spindle and spindle bearing in high speed rotation. Generally, high speed machining is considered when the rotating speed is more than 8,000 rpm. At that time, the life time of tool is reduced to about 50% and the roughness of machining surface is worse as the run-out is increased to 10 micron. The life time of tool could be increased by making monitoring of tool-setup easy, quick and precise in high speed machining tool. This means the consumption of tool is much more reduced. And also it reduces the manufacturing cost and increases the productivity by reducing the tool-setup time of operator. In this study, in order to establish the concept of tool-setup monitoring the measuring method of the geometrical error of tool system is studied when the spindle is stopped. And also the measuring method of run-out, dynamic error of tool system, is studied when the spindle is rotated in 8,000${\sim}$60,000 rpm. The dynamic phenomena of tool-setup are analyzed by implementing the monitoring system of rotating tool system and the non-contact measuring system of micro displacement in high speed.

• 한국터널지하공간학회 논문집
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• 제5권4호
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• pp.349-360
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• 2003

본 연구에서는 절리를 포함한 터널주변 암반의 안전성 강화 및 지하수 유입 억제공으로 사용되는 침투그라우팅에 대한 모형화 기법을 제시하고 관련 매개변수 해석을 실시하였다. Bingham 모형을 적용한 시멘트 그라우팅재는 정상류 흐름으로 가정하여 해석의 편의를 도모하였으며 UDEC을 이용한 해석결과, 절리의 두께 및 주입압이 침투그라우팅에 의한 확산범위를 결정짓는 주요 변수임을 확인하였다. 침투그라우팅 모형을 근간으로 할렬그라우팅 해석을 위한 수치모형을 제안하였으며 암반의 인장강도와 점착력이 할렬의 주요변수임을 입증하였다. 한편, 주입후 지반보강효과를 정량적으로 검토하기 위하여 직교 이방성 물성을 계산할 수 있는 알고리즘을 제시하였으며 이 결과 주입후 약 3~4배 정도의 강성도 증진효과를 확인하였다. 향후 본 연구결과는 그라우팅재 주입에 의한 투수계수 저감효과 혹은 지하수 억제공법 등의 설계기법에 적용될 수 있으며 관련 실험도 수행될 예정이다.

• Steel and Composite Structures
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• 제21권5호
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• pp.1157-1182
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• 2016

A newly puzzle shape of crestbond rib shear connector is a type of ductile perfobond rib shear connector. This shear connector has some advantages, including relatively easy rebar installation and cutting, as well as the higher shear resistance strength. Thus, this study proposed a newly puzzle shape of crestbond rib with a "${\mho}$" shape, and its shear resistance behaviors and shear strengths were examined using push-out tests. Five main parameters were considered in the push-out specimens to evaluate the effects of shear resistance parameters such as the dimensions of the crestbond rib, transverse rebars in the crestbond dowel, concrete strength, rebar strength, and dowel action on the shear strength. The shear loading test results were used to compare the changes in the shear behaviors, failure modes, and shear strengths. It was found that the concrete strength and number of transverse rebars in the crestbond rib were significantly related to its shear resistance. After the initial bearing resistance behavior of the concrete dowel, a relative slip occurred in all the specimens. However, its rigid behavior to shear loading decreased the ductility of the shear connection. The cross-sectional area of the crestbond rib was also shown to have a minor effect on the shear resistance of the crestbond rib shear connector. The failure mechanism of the crestbond rib shear connector was complex, and included compression, shear, and tension. As a failure mode, a crack was initiated in the middle of the concrete slab in a vertical direction, and propagated with increasing shear load. Then, horizontal cracks occurred and propagated to the front and rear faces of the specimens. Based on the results of this study, a design shear strength equation was proposed and compared with previously suggested equations.

• 대한한방내과학회지
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• 제23권2호
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• pp.202-211
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• 2002

1. Background The previous studies on anticancer medicine derived from korean traditional medicine have focused on the life elongation of cancer cell bearing animals. However, it is thought that more molecular biological studies are needed to reveal their mechanism. 2. Objective The aim of this study was to investigate the molecular biological function of Sagunjatang plus Cremastrae Appenediculatae Tuber on cytostaticity, apoptosis and apoptosis related genes revelation against human stomach cancer cells(AGS). 3. Methods After administrating Sagunjatang and Sagunjatang plus Cremastrae Appenediculatae Tuber to human stomach cancer cell. MTT assay was performed to compare and examine the efficacy of each medicine on the cytostaticity of stomach cancer cells in proportion to time and doses, and apoptosis assay was performed to examine their effect on apoptosis by using DAPI dye and counting the number of cells which developed in an apoptotic body. In addition, the quantitative RT-PCR was used to examine their effect on the revelation of Bcl-2, Bax and P53, which are genes related to apoptosis. 4. Result and Conclusion Sagunjatang plus Cremastrae Appenediculatae Tuber demonstrated increased cytostaticity. decreased apoptosis and unremarkable revelation of apoptosis related genes. But in the cytostaticity and apoptosis, Sagunjatang plus Cremastrae Appenediculatae Tuber showed a tendency to control stomach cancer cells. Therefore, we can expect the clinical application to the related diseases. Besides, it needs another experiment on various cancer cells, such as, lung cancer cell and hysterocarcinoma cell.

• Bulletin of the Korean Chemical Society
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• 제32권6호
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• pp.1884-1890
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• 2011

A series of Ni(II) and Pd(II) complexes bearing N4-type tetradentate ligands, [Ni($X^1X^2$-6-$Me_2bpb$) 1] and [Pd($X^1X^2$-6-$Me_2bpb$) 2]; 6-$Me_2bpb$ = N,N'-(o-phenylene)bis(6-methylpyridine-2-carboxamidate), $X^1$ = Cl, H, or $CH_3$, $X^2$ = $NO_2$, Cl, F, H, $CH_3$, or $OCH_3$) were designed, synthesized, and characterized to investigate electronic and steric effects of ligand on the norbornene polymerization catalysts. Using modified methylaluminoxanes as an activator, the complexes exhibited high catalytic activities for the polymerization of norbornene and the nickel complexes exhibited better catalytic activity the palladium complexes. Ni complex 1a with $NO_2$ group on the benzene ring showed the highest catalytic activity of $4.9{\times}10^6$ g of PNBEs/$mol_{Ni}{\cdot}h$ and molecular weight of $15.28{\times}10^5$ g/mol with PDI < 2.30. Complexes with electron-withdrawing groups are more thermally stable (> 100 $^{\circ}C$), and tend to afford higher polymerization productivities than the ones having electron-donating groups. Amorphous polynorbornenes were obtained with good solubility in halogenated aromatic solvents. A vinyl addition mechanism has been proposed for the catalytic polymerization.