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Proton Therapy Review: Proton Therapy from a Medical

  • Lee, Se Byeong
    • Progress in Medical Physics
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    • v.31 no.3
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    • pp.99-110
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    • 2020
  • With hope and concern, the first Korean proton therapy facility was introduced to the National Cancer Center (NCC) in 2007. It added a new chapter to the history of Korean radiation therapy. There have been challenging clinical trials using proton beam therapy, which has seen many impressive results in cancer treatment. Compared to the rapidly increasing number of proton therapy facilities in the world, only one more proton therapy center has been added since 2007 in Korea. The Samsung Medical Center installed a proton therapy facility in 2015. Most radiation oncology practitioners would agree that the physical properties of the proton beam provide a clear advantage in radiation treatment. But the expensive cost of proton therapy facilities is still one of the main reasons that hospitals are reluctant to introduce them in Korea. I herein introduce the history of proton therapy and the cutting edge technology used in proton therapy. In addition, I will cover the role of a medical physicist in proton therapy and the future prospects of proton therapy, based on personal experience in participating in proton therapy programs from the beginning at the NCC.

Improved Rainfall Estimation Based on Corrected Radar Reflectivity in Partial Beam Blockage Area of S-band Dual-Polarization Radar (S밴드 이중편파레이더의 부분 빔 차폐영역 내 반사도 보정을 통한 지상강우추정 개선)

  • Lee, Jeong-Eun;Jung, Sung-Hwa;Kim, Hae-Lim;Lee, Sun-Ki
    • Atmosphere
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    • v.27 no.4
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    • pp.467-481
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    • 2017
  • A correction method of reflectivity in partial beam blockage (PBB) area is suggested, which is based on the combination of digital terrain information and self-consistency principle between polarimetric observation. First, the reflectivity was corrected by adding the radar energy loss estimated from beam blockage simulation using digital elevation model (DEM) and beam propagation geometry in standard atmosphere. The additional energy loss by unexpected obstacles and non-standard beam propagation was estimated by using the coefficient between accumulated reflectivity ($Z_H$) and differences of differential phase shift (${\Phi}_{DP}$) along radial direction. The proposed method was applied to operational S-band dual-polarization radar at Jindo and its performance was compared with those of simulation method and self-consistency method for six rainfall cases. When the accumulated reflectivity and increment of ${\Phi}_{DP}$ along radial direction are too small, the self-consistency method has failed to correct the reflectivity while the combined method has corrected the reflectivity bias reasonably. The correction based on beam simulation showed the underestimation. For evaluation of rainfall estimation, the FBs (FRMSEs) of simulation method and self-consistency principle were -0.32 (0.59) and -0.30 (0.57), respectively. The proposed method showed the lowest FB (-0.24) and FRMSE (0.50). The FB and FMSE were improved by about 18% and by 19% in comparison to those before correction (-0.42 and 0.70). We can conclude that the proposed method can improve the accuracy of rainfall estimation in PBB area.

Structural Design of the Light Weight Axle Beam for Medium Duty Commercial Vehicle Using Hot Press (중형 상용차용 프레스 성형 차축빔의 경량화 설계)

  • Sim, Kijoong;Shin, Hangwoo;Cho, Wonyoung;Choi, Gyoojae;Lee, Youngchoon;Son, Youngho;Jeon, Namjin
    • Transactions of the Korean Society of Automotive Engineers
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    • v.23 no.4
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    • pp.371-379
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    • 2015
  • This paper represents the structural design of the light weight axle beam for medium duty commercial vehicle using hot press. To reduce the weight of the axle, axle beam of solid type was replaced by hollow type which was made by hot press. According to the change of axle beam structure and manufacturing method, we have to investigate the structural strength and fatigue performance. To verify the axle beam performance, the structural analysis was carried out by simplified axle beam model and various design parameters that are axle beam height, thickness and width. From the analysis results, the light weight axle beam structure was founded and applied the full model analysis. This study will be used as a guidance in development of the light weight axle for medium duty commercial vehicle.

Fast Neutron Beam Dosimetry (속중성자선의 선량분포에 관한 연구)

  • Lee Hyo Nam;Ji Young Hoon;Ji Kwang Soo;Lee Dong Han
    • The Journal of Korean Society for Radiation Therapy
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    • v.9 no.1
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    • pp.71-81
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    • 1997
  • I. Objective and Importance of the Project We have been using MC-50 cyclotron and NT-50 neutron therapy machine for treating cancer patients since 1986 at Korea Cancer Center Hospital. It is mandatory to measure accurately the dose distribution and the total absorbed dose of fast neutron for putting it to the clinical use. At present the methods of measurement of fast neutron are proposed largely by American Associations of Physicists in Medicine (Task Group 18), European Clinical Neutron Dosimetry Group, and International Commission on Radiation Units and Measurements. The complexity of measurement, however, induce the methodological differences between them. In our study, therefore, we tried to establish a unique technique of measurement by means of measuring the emitted doses and the dose distribution of fast neutron beam from neutron therapy machine, and to invent a standard method of measurement adequate to our situation. II. Scope and Contents of the Project For establishing a unique technique of measurement and inventing a standard method of measurement of fast neutron beam, 1. to grasp the physical characteristics of neutron therapy machine 2. to study the principles for measrement of fast neutron beam 3. to get the dose distribution (dose rate, percent-depth dose, flatness etc) throught the actual measurement 4. to compare our data with those being cited world-widely.

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Dynamic plastic response of a hinged-free beam subjected to impact at an arbitrary location along its span

  • Zhang, Y.;Yang, J.L.;Hua, Y.L.
    • Structural Engineering and Mechanics
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    • v.14 no.5
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    • pp.611-624
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    • 2002
  • In this paper, a complete solution is presented for dynamic plastic response of a rigid, perfectly plastic hinged-free beam, of which one end is simply supported or hinged and the other end free, subjected to a transverse strike by a travelling mass at an arbitrary location along its span. The governing differential equations are expressed in non-dimensional forms and solved numerically to obtain the instantaneous deflection of the beam and the plastic dissipated energy in the beam. The dynamic behavior for a hinged-free beam is more complicated than that of a free-free beam. It transpires that the mass ratio and impact position have significant influence on the final deformation. In the aspect of energy dissipation, unlike simply supported or clamped beams for which the plastic deformation consumes almost the total input energy, a considerable portion of the input energy would be transferred as rigid-body motion of hinged-free beam, and the energy dissipated in its plastic deformation is greatly reduced.

Comparison of knife-edge and multi-slit camera for proton beam range verification by Monte Carlo simulation

  • Park, Jong Hoon;Kim, Sung Hun;Ku, Youngmo;Lee, Hyun Su;Kim, Chan Hyeong;Shin, Dong Ho;Jeong, Jong Hwi
    • Nuclear Engineering and Technology
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    • v.51 no.2
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    • pp.533-538
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    • 2019
  • The mechanical-collimation imaging is the most mature technology in prompt gamma (PG) imaging which is considered the most promising technology for beam range verification in proton therapy. The purpose of the present study is to compare the performances of two mechanical-collimation PG cameras, knife-edge (KE) camera and multi-slit (MS) camera. For this, the PG cameras were modeled by Geant4 Monte Carlo code, and the performances of the cameras were compared for imaginary point and line sources and for proton beams incident on a cylindrical PMMA phantom. From the simulation results, the KE camera was found to show higher counting efficiency than the MS camera, being able to estimate the beam range even for $10^7$ protons. Our results, however, confirmed that in order to estimate the beam range correctly, the KE camera should be aligned, at least approximately, to the location of the proton beam range. The MS camera was found to show lower efficiency, being able to estimate the beam range correctly only when the number of the protons is at least $10^8$. For enough number of protons, however, the MS camera estimated the beam range correctly, errors being less than 1.2 mm, regardless of the location of the camera.

Dosimetry by Using EBT2 Film for Total Skin Electron Beam Therapy (TSET) (전신 피부 전자선 치료(TSET)에서 EBT2 필름을 사용한 선량측정)

  • Hwang, Ui-Jung;Rah, Jeong-Eun;Jeong, Ho-Jin;Ahn, Sung-Hwan;Kim, Dong-Wook;Lee, Sang-Yeob;Lim, Young-Gyung;Yoon, Myong-Geun;Shin, Dong-Ho;Lee, Se-Byeong;Park, Sung-Young;Pyo, Hong-Ryull;Chung, Weon-Kuu
    • Progress in Medical Physics
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    • v.21 no.1
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    • pp.60-69
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    • 2010
  • For treatment of Total Skin Electron beam Therapy (TSET), measurement of dose at various conditions is need on the contrary to usual radiotherapy. When treating TSET with modified Stanford technique based on linear accelerator, the energy of treatment electron beam, the spatial dose distribution and the actual doses deposited on the surface of the patient were measured by using EBT2. The measured energy of the electron beam was agreed with the value that measured by ionization chamber, and the spatial dose distribution at the patient position and the doses at several point on the patient's skin could be easily measured by EBT2 film. The dose on the patient that was measured by EBT2 film showed good agreement with the data measured simultaneously by TLD. With the results of this study, it was proven that the EBT2 film can be one of the useful dosimeter for TSET.

Effects of Material Anisotropy on Ultrasonic Beam Propagation: Diffraction and Beam Skew

  • Jeong, Hyun-Jo;Schmerr, W.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.26 no.3
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    • pp.198-205
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    • 2006
  • The necessity of nondestructively inspecting austenitic steels, fiber-reinforced composites, and other inherently anisotropic materials has stimulated considerable interest in developing beam models for anisotropic media. The properties of slowness surface playa key role in the beam models based on the paraxial approximation. In this paper, we apply a modular multi-Gaussian beam (MMGB) model to study the effects of material anisotropy on ultrasonic beam profile. It is shown that the anisotropic effects of beam skew and excess beam divergence enter into the MMGB model through parameters defining the slope and curvature of the slowness surface. The overall beam profile is found when the quasilongitudinal(qL) beam propagates in the symmetry plane of transversely isotropic austenitic steels. Simulation results are presented to illustrate the effects of these parameters on ultrasonic beam diffraction and beam skew. The MMGB calculations are also checked by comparing the anisotropy factor and beam skew angle with other analytical solutions.

Trend of Laser Beam Welding Technology (고밀도 열원방식 레이저빔 용접의 연구동향)

  • Kim, H.T.;Kil, S.C.
    • Proceedings of the KAIS Fall Conference
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    • 2011.12b
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    • pp.481-484
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    • 2011
  • The increasing interest in the laser beam welding is placing stringent demands on the manufacturing techniques and performance requirements, and the manufacture employs the high quality and efficiency laser beam welding technology. This paper covers recent research trends of the laser beam welding technology including the laser beam surfacing and laser beam cladding technology.

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An Experimental Study on the Flexural Strength of Hybrid Beam (하이브리드 보의 휨성능에 관한 실험적 연구)

  • Hong, Sung-Gul;Yang, Dong-Hyun;Lim, Byung-Ho;Ryu, Jae-Chun
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.05a
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    • pp.398-401
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    • 2006
  • This study investigates the behaviour of Hybrid Beam with reinforced concrete encased steel center and reinforced concrete end. Two types of encased steel shape and two sections are examined in this study. Test results showed that H-Hybrid beam is stronger than Honey-comb Hybrid beam, and the behaviour of composite beam embedded steel at the elastic state is same as that of simple beam.

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