• Title/Summary/Keyword: Bayesian Design

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Report of the 3rd Japan-Korea Workshop on Acupuncture and EBM;Protocol development for the acupuncture trial on the osteoarthritis of the knee

  • Jang, Jun-Hyouk;Kenji, Kawakita;Hahn, Seo-Kyung;Park, Hi-Joon;Lee, Seung-Deok;Kim, Yong-Suk;Norihito, Takahashi;Toshiyuki, Shichidou;Kazunori, Itoh;Eiji, Sumiya;Eiji, Furuya;Hitoshi, Yamashita;Hiroshi, Tsukayama
    • Journal of Acupuncture Research
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    • v.23 no.6
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    • pp.239-254
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    • 2006
  • The 3rd Japan-Korea Workshop on Acupuncture and EBM was held at Kanazawa on June $16^{th}$. From Korea team, 4 papers were presented. Dr. Hahn introduced a new approach of data analysis on series of n-of-1 trials using the Bayesian statistics. It offered important information for the future n-of-1 trials. Dr. Park clearly demonstrated the significance of various sham devices proposed and stressed the importance of research questions when we choose the control intervention in RCT. Dr. Lee reported the results of survey in Korean Medical Doctors (KMD) for their point selection and techniques to the distal and local points. Dr. Kim presented the results of face to face survey on the KMD with 28 items for acupuncture treatment on the knee OA. Finally, a draft of protocol was introduced by Dr. Kim. The title was "multi-center, a randomized, single blinded, two arms, parallel-group study to compare the effectiveness and safety of 'individualized acupuncture' and 'standardized minimal acupuncture' in Korean and Japanese patients with knee osteoarthritis (Phase IV)". From Japan team, 7 speakers presented their comments and proposals on the protocol. Dr. Takahashi introduced several issues regarding n-of-1 trials and pointed out the importance of obtaining generalizability from n-of-1 trials. Dr. Shichidou pointed the importance of research design, selection of outcome measures and reduction of biases. Dr. Itoh presented the results of point selection for the knee OA based on the literature survey. Dr. Sumiya introduced several differences between KMD and Japanese acupuncturists based on the questionnaire used in KMD survey. Dr. Furuya demonstrated a result of press tack needle and its sham device on shoulder stiffness. Dr. Yamashita introduced the results of literature survey regarding adverse events occurred by acupuncture on knee OA. Dr.Tsukayama stressed the importance of responsibility of Institutional Review Board (IRB) for the conduction of clinical trials. After several issues were discussed, the need of continued meeting for final protocol development was agreed, then the workshop was closed.

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Performance Based Evaluation of Concrete Material Properties from Climate Change Effect on Wind Speed and Sunlight Exposure Time Curing Condition (기후변화의 풍속과 일조시간에 따른 콘크리트 재료특성의 성능 중심 평가)

  • Kim, Tae-Kyun;Shin, Jae-Ho;Bae, Deg-Hyo;Kim, Jang-Ho Jay
    • Journal of the Korea Concrete Institute
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    • v.26 no.6
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    • pp.751-759
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    • 2014
  • Currently, due to global warming, occurrences of extreme climate phenomena such as heat wave, heavy snow, heavy rain, super typhoon are continuously increasing all over the world. Due to these extreme climate phenomena, concrete structures and infrastructures are exposed to serious deterioration and damage. However, researches on construction technologies and standards to confront the climate change generated problems are needed presently. In order to better handle these problems, the validity of the present concrete mixture proportions are evaluated considering wind speed and sunlight exposure time based on climate change record in Seoul, Korea. The specimens cured at various wind speed and sunlight exposure time conditions were tested to obtain their compressive and split tensile strengths at various curing ages. Moreover, performance based evaluation (PBE) method was used to analyze the target strength satisfaction percentage of the concrete cured for the curing conditions. From the probabilistic method of performance evaluation of concrete performance, feasibility and usability of current concrete mix design practice for climate change conditions can be evaluated.

The Effect of Rain on Traffic Flows in Urban Freeway Basic Segments (기상조건에 따른 도시고속도로 교통류변화 분석)

  • 최정순;손봉수;최재성
    • Journal of Korean Society of Transportation
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    • v.17 no.1
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    • pp.29-39
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    • 1999
  • An earlier study of the effect of rain found that the capacity of freeway systems was reduced, but did not address the effects of rain on the nature of traffic flows. Indeed, the substantial variation due to the intensity of adverse weather conditions is entirely rational so that its effects must be considered in freeway facility design. However, all of the data in Highway Capacity Manual(HCM) have come from ideal conditions. The primary objective of this study is to investigate the effect of rain on urban freeway traffic flows in Seoul. To do so, the relations between three key traffic variables(flow rates, speed, occupancy), their threshold values between congested and uncontested traffic flow regimes, and speed distribution were investigated. The traffic data from Olympic Expressway in Seoul were obtained from Imagine Detection System (Autoscope) with 30 seconds and 1 minute time periods. The slope of the regression line relating flow to occupancy in the uncongested regime decreases when it is raining. In essence, this result indicates that the average service flow rate (it may be interpreted as a capacity of freeway) is reduced as weather conditions deteriorate. The reduction is in the range between 10 and 20%, which agrees with the range proposed by 1994 US HCM. It is noteworthy that the service flow rates of inner lanes are relatively higher than those of other lanes. The average speed is also reduced in rainy day, but the flow-speed relationship and the threshold values of speed and occupancy (these are called critical speed and critical occupancy) are not very sensitive to the weather conditions.

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