• Title/Summary/Keyword: Basic Research Program

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Isolation and Characterization of a Novel Calcium/Calmodulin-Dependent Protein Kinase, AtCK, from Arabidopsis

  • Jeong, Jae Cheol;Shin, Dongjin;Lee, Jiyoung;Kang, Chang Ho;Baek, Dongwon;Cho, Moo Je;Kim, Min Chul;Yun, Dae-Jin
    • Molecules and Cells
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    • v.24 no.2
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    • pp.276-282
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    • 2007
  • Protein phosphorylation is one of the major mechanisms by which eukaryotic cells transduce extracellular signals into intracellular responses. Calcium/calmodulin ($Ca^{2+}/CaM$)-dependent protein phosphorylation has been implicated in various cellular processes, yet little is known about $Ca^{2+}/CaM$-dependent protein kinases (CaMKs) in plants. From an Arabidopsis expression library screen using a horseradish peroxidase-conjugated soybean calmodulin isoform (SCaM-1) as a probe, we isolated a full-length cDNA clone that encodes AtCK (Arabidopsis thaliana calcium/calmodulin-dependent protein kinase). The predicted structure of AtCK contains a serine/threonine protein kinase catalytic domain followed by a putative calmodulin-binding domain and a putative $Ca^{2+}$-binding domain. Recombinant AtCK was expressed in E. coli and bound to calmodulin in a $Ca^{2+}$-dependent manner. The ability of CaM to bind to AtCK was confirmed by gel mobility shift and competition assays. AtCK exhibited its highest levels of autophosphorylation in the presence of 3 mM $Mn^{2+}$. The phosphorylation of myelin basic protein (MBP) by AtCK was enhanced when AtCK was under the control of calcium-bound CaM, as previously observed for other $Ca^{2+}/CaM$-dependent protein kinases. In contrast to maize and tobacco CCaMKs (calcium and $Ca^{2+}/CaM$-dependent protein kinase), increasing the concentration of calmodulin to more than $3{\mu}M$ suppressed the phosphorylation activity of AtCK. Taken together our results indicate that AtCK is a novel Arabidopsis $Ca^{2+}/CaM$-dependent protein kinase which is presumably involved in CaM-mediated signaling.

Design of 32 bit Parallel Processor Core for High Energy Efficiency using Instruction-Levels Dynamic Voltage Scaling Technique

  • Yang, Yil-Suk;Roh, Tae-Moon;Yeo, Soon-Il;Kwon, Woo-H.;Kim, Jong-Dae
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.9 no.1
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    • pp.1-7
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    • 2009
  • This paper describes design of high energy efficiency 32 bit parallel processor core using instruction-levels data gating and dynamic voltage scaling (DVS) techniques. We present instruction-levels data gating technique. We can control activation and switching activity of the function units in the proposed data technique. We present instruction-levels DVS technique without using DC-DC converter and voltage scheduler controlled by the operation system. We can control powers of the function units in the proposed DVS technique. The proposed instruction-levels DVS technique has the simple architecture than complicated DVS which is DC-DC converter and voltage scheduler controlled by the operation system and a hardware implementation is very easy. But, the energy efficiency of the proposed instruction-levels DVS technique having dual-power supply is similar to the complicated DVS which is DC-DC converter and voltage scheduler controlled by the operation system. We simulate the circuit simulation for running test program using Spectra. We selected reduced power supply to 0.667 times of the supplied power supply. The energy efficiency of the proposed 32 bit parallel processor core using instruction-levels data gating and DVS techniques can improve about 88.4% than that of the 32 bit parallel processor core without using those. The designed high energy efficiency 32 bit parallel processor core can utilize as the coprocessor processing massive data at high speed.

The Meta-analysis of the Effects of Meditation Programs of the Elderly (노인대상 명상프로그램 효과성 메타분석)

  • Kim, Gyeryung;Kim, Ilsik
    • 한국노년학
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    • v.38 no.1
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    • pp.47-63
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    • 2018
  • The purpose of this research was to present the basic data for developing meditation programs by verifying the effect size using meta-analysis of the results from previous studies on meditation program of the elderly. In order to analyze the effect sizes of program types, group of mediating variables and activity factors of elderly meditation programs, this study reviewed 24 precedent research that have been conducted from 2003 through April 2017 in Korea using meta-analysis and summarized the effect sizes are as follows. First, the overall average effect size was .914, which was great. Among the program types, complex meditation was 1.726, which was the greatest. Among the group of mediating variables, the positive psychological variable group had the highest in 1.368 and the gender consists only of women had the highest in .921. Secondly, concerning the activity factors, when the total number of sessions was 12~20 times(1.193), sessions per week was twice(1.254), time went for 110~120 minutes per session(1.581) and the group size was 71~100 persons(1.535) that were shown as higher effect size. Among the types of publications, articles in journals(1.062) had a higher effect size than dissertations(.817). For the organizing elderly meditation program in the future, I suggest that the program type of complex meditation, 12~20 time of total sessions, twice a week, 110~120 minutes of activity hours. At the time we entered the aged society, this study is meaningful in that it provides the basic data for future program development by confirming the effect size according to program types, mediation variables and activity factors for the meditation program performed for the elderly.

A Study on Establishing Infrastructure Plans to Introduce an Energy Efficiency Resource Standards - Based on the Energy Demand Side Management and Energy Efficiency Potential - (에너지효율향상의무화제도의 국내 도입을 위한 기반구축 연구 - 에너지수요관리제도 및 절감률 산정 중심으로 -)

  • Hong, Sung-Jun;Choi, Bong-Ha;Lee, Deok-Ki;Park, Soo-Uk;Won, Jong-Ryul
    • Transactions of the Korean hydrogen and new energy society
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    • v.21 no.3
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    • pp.241-247
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    • 2010
  • An Energy Efficiency Resource Standards (EERS) is a simple, market-based mechanism to encourage more efficient generation, transmission, and use of electricity, natural gas and heat. An EERS consists of electric, gas and/or heating energy savings targets for utilities, often with flexibility to achieve the target through a market-based trading system. In this paper, we make persons acquainted with EERS programs of foreign countries in these days. And we analyze domestic energy demand side management (DSM) programs in order to introduce an EERS program into the country successfully. Energy efficiency potential calculated in 2007 is one of the important factors for establishing an EERS program domestically. This study may provide basic data to set the amount of energy saving when an EERS program would be phased in.

An Exploratory Study on the Introduction of the Basic Income Program for Farmers - Focucing on Chungcheongnam-do - (농민기본소득제 도입에 관한 탐색적 연구 - 충청남도를 중심으로 -)

  • Park, Kyong-Cheol
    • Journal of Agricultural Extension & Community Development
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    • v.23 no.1
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    • pp.73-87
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    • 2016
  • The purpose of this study is to analyze the trends of basic income guarantee of which the discussion has been spreading in recent years and to explore the feasibility of this system in the rural areas of Chungchengnam-do. Basic Income Guarantee means a system in which all members of society could take regular incomes which is at a minimum necessary for their life without any conditions, and it is already introduced or being currently discussed in several countries and regions such as USA, Switzerland, Namibia. In Korea, it is currently claimed that breakthrough policy such as basic income guarantee for farmers should be introduced for farmers or rural residents who are facing the challenges of the double, namely the reduction of farm incomes and rural population due to the expansion of global free trade such as WTO and FTA since 1990s. Therefore, the policy considerations and suggestions for implementing the basic income guarantee for farmers in Chungcheongnam-do is explained in this paper.

Experiencing Design Foundation in On-Line Education - By Using The Basic Graphic Tools - (디지털 학습 환경에서의 기초디자인 교육 - 기초디자인 훈련 도구(Basic Graphic Tools)의 개발을 중심으로 -)

  • Lee, Eun-Joo
    • Archives of design research
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    • v.18 no.2 s.60
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    • pp.255-264
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    • 2005
  • The development of personal computers and the Internet led to changes of instructor-student and student-student relationships in design education. New resources of design education with proper materials and tools have to be offered for teaching and learning. The purpose of this research is to develop Basic Graphic Tools(BGTs) on screen that help students to practice the design principles, and to evaluate the BGTs' usability to enhance the credibility of extra tools for online design learning. The BGTs has to be developed to minimize the gap between the online and traditional classroom settings and to maximize the diverse advantage of lecture content driven from technology. Students were given certain design requirements to explore BGTs and a learning guide/performance test after the lecture to evaluate the tools. The test was performed under the e-learning program serviced by C college. This research has presented some encouraging results and raises questions toward future work: how do BGTs impact the feasibility of an online design lecture.

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An Analysis of the Trends in the Arena of Cooperation by the International Research Cooperation Related Experts

  • Noh, Younghee;Ro, Ji Yoon;Kwak, Woojung
    • International Journal of Knowledge Content Development & Technology
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    • v.11 no.4
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    • pp.53-86
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    • 2021
  • The International Research Cooperation Information Center has carried out a project to collect the DBs related to the international research cooperation information, and build an online service system. This study seeks to examine and understand the trends of international research cooperation by analyzing the data corresponding to the other international cooperation DBs such as symposium and seminar, which may be said to be the arena of cooperation by the international research cooperation related experts, among the international research cooperation information DBs collected by the International Research Cooperation Information Center. The other international cooperation DBs are divided into the international cooperation consortium, international cooperation symposium, international research cooperation seminar, international training program, international research cooperation workshop, and the international research cooperation equipment / facility. It seems that, based on the research results, it is necessary to hold international cooperation programs, seminars, and workshops, among others, with a focus on the themes to recover the trends of international cooperation as in the past, and recover from the pandemic situation. The results of this study may be utilized as the basic data for the researchers related to the international research cooperation, and furthermore, by analyzing various international research cooperation information DBs in a multi-faceted manner, the studies analyzing the research trends of international research cooperation by field, subject, and type may be conducted, and the facilitation of the international research cooperation in Korea is expected moving forward.

A Study on the Neighborhood Management(QM) Program for the Regeneration of Deteriorated Residential Blocks in Berlin (베를린의 노후주거지 재생을 위한 근린재생(QM)프로그램 연구)

  • Yoo, Hae-Yeon;Park, Yeon-Jeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3969-3982
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    • 2014
  • This study examined the QM(Quartier Management) Program of Germany for the Regeneration of Deteriorated Residential Blocks in Berlin. This study used basic data research for the 'Neighborhood Management Program' in South Korea. Therefore, German local documents, organization web sites, internal reports were analyzed to understand the status of the Germany's urban regeneration policies and present the conditions. This study was conducted by local interviews, e-mail exchanges and telephone interviews. The following were investigated and analyzed: 1) the present conditions of the urban regeneration policies and regional regeneration in Germany; 2) the characteristics of the QM program (Program's strategy, funding and utilization plans, program's applicable areas, Indicators for regional selection); and 3) examine two cases of the QM Program in Berlin.

A Study on Developing Cultural Education Program for Female Marriage Immigrants in Korea (여성 결혼이민자 문화교육 프로그램 개발을 위한 시론적 연구)

  • Oh, Yoon-Ja
    • Journal of Family Resource Management and Policy Review
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    • v.12 no.4
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    • pp.63-77
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    • 2008
  • This study was performed to develop the basic framework of multicultural art education programs for female foreign immigrants married to Korean males. First, these programs aim to lessen their cultural variance in acculturizing in Korea, and thereafter enhance their emotional stability and improve their creative ability to integrate cultural diversity into family life. The primary objective of this study was to offer a suitable education program and evaluation criteria for the program; the research has been done through person-to person interviews with 53 subjects using a series of questionnaires composed of 8 five-point Likert-Scaled items. As for the process of the interview, the subjects were asked about their satisfaction with each program item twice in order to comparetheir impressions before and after program participation. The satisfaction scores were analyzed using frequency distribution. In addition, the program effects were also evaluated by coordinators and developers from their subjective comments through periodical evaluation meetings. From the results, it is observed that art education programs are beneficial for improving female immigrants' emotionaland cultural integration. In addition, experts determined that the programs were helpful for improving their human relationship and acculturization in Korea. Finally, it is concluded that multicultural education programs are a primary fundamental infra-structural way of integrating diverse cultures and improving communication exchanges, and therefore, improve family stability among the multicultural families in Korea.

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A Qualitative Study on Steering of Education Accreditation: With Case Study on Korean Medicine Education (학문분야별 평가인증제 운영에 관한 질적 사례 연구: 한의학을 중심으로)

  • Seo, Dongin;Shin, Sangwoo
    • The Journal of Korean Medicine
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    • v.40 no.3
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    • pp.21-34
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    • 2019
  • Objectives: The purpose of this article is to develop steering of program accreditation system in Korean Medicine Education through meta-evaluation. For this study, the subjects of our research were categorized as the accreditation criteria and system, results and effects, tasks for improvement on Korean Medicine Education. Methods: We conducted Focus Group Interview on 102 full-time professors with experience of participating on accreditation of Korean Medicine Education from 12 college of Korean Medicine Education and we analyzed it by thematic analysis. Results: The accreditation criteria and program evaluation system of Korean Medicine were listed as 'Confusion about the goals of program evaluation', 'High hurdles on accreditation', 'obsession to success cases', 'Small college complaints about applying the same criteria', 'Dilemma of quantitative and qualitative evaluation'. The results and effects of program evaluation in Korean Medicine Education were listed as 'Establishment of base infrastructure for basic medical education', 'Benchmarking and exchanging opinions through evaluation certification', 'Resistance to documents and document-based evaluation', and 'Double-sided of evaluation certification'. As for the tasks for further improvement, the following list is suggested. 'Actively promote evaluation certification', 'Simplification and standardization of forms', 'Requesting for activating about Evaluation committee', 'Need for consulting before regular evaluation'. Conclusion: It is necessary to upgrade the accreditation system and make efforts to improve the issues discovered for better Korean Medicine Education.