• 제목/요약/키워드: Baseline profile

검색결과 121건 처리시간 0.025초

과체중인 여성에서 체중 감소 보조제를 이용한 체중 및 내장지방의 감소 효과 (The Effect of a Potential Antiobesity-Supplement on Weight Loss and Visceral Fat Accumulation in Overweight Women)

  • 차보람;채지숙;이종호;장양수;이진희;손종욱
    • Journal of Nutrition and Health
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    • 제36권5호
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    • pp.483-490
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    • 2003
  • Chitosan, hydroxycitrate and L-carnitine have been known to be antiobesity components. The purpose of this study was to evaluate the combined effects of chitosan, hydroxycitrate and L-carnitine mixture as a potential antiobesity supplement in overweight women. Pre-menopausal healthy females who were overweight (percent ideal body weight > 110) were included in this study. Forty-nine subjects randomly received a placebo (n = 25) or antiobesity-supplement (n = 24), which was a mixture of chitosan, hydroxycitrate, and L-carnitine. Before and after the eight-week experimental period, anthropometric parameters, blood components and computerized tomography were measured. At baseline, the two groups were well matched in terms of age, body mass index and lipid profile. After the eight weeks of potential antiobesity supplementation, the subjects' body fat percent had decreased significantly (p < 0.001) by 5.6% (39.1 $\pm$ 1 vs 36.9 $\pm$ 1%) while lean body mass increased (p < 0.01). Vsceral fat area at the L4 vertebra decreased significantly (p < 0.01) by 8.6% in the supplemented group and the total fat area at the L4 vertebra showed a tendency to decrease (p = 0.051) by 2.4%. Also, in the group given the antiobesity-supplement rather than the placebo, the fasting triglyceride level decreased significantly (p < 0.05) by 10.0%. In addition, serum total cholesterol levels in the antiobesity-supplement group showed a tendency to decrease (p=0.159) by 2.7% (194 $\pm$ 6 vs 189 $\pm$ 6 mg/dl). No side effects were found in either group during the intervention. In conclusion, the present study demonstrated that taking a mixture of chitosan, hydroxycitrate, and L-carnitine as a potential antiobesity supplement for eight weeks produced advantageous changes in the weight and visceral fat accumulation of overweight women without any side effects. (Korean J Nutrition 36(5): 483~490, 2003)

Development of an Advanced Rotorcraft Preliminary Design Framework

  • Lim, Jae-Hoon;Shin, Sang-Joon;Kim, June-Mo
    • International Journal of Aeronautical and Space Sciences
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    • 제10권2호
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    • pp.134-139
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    • 2009
  • Various modules are generally combined with one another in order to perform rotorcraft preliminary design and its optimization. At the stage of the preliminary design, analysis fidelity is less important than the rapid assessment of a design is. Most of the previous researchers attempted to implement sophisticated applications in order to increase the fidelity of analysis, but the present paper focuses on a rapid assessment while keeping the similar level of fidelity. Each small-sized module will be controlled by an externally-operated global optimization module. Results from each module are automatically handled from one discipline to another which reduces the amount of computational effort and time greatly when compared with manual execution. Automatically handled process decreases computational cycle and time by factor of approximately two. Previous researchers and the rotorcraft industries developed their own integrated analysis for rotorcraft design task, such as HESCOMP, VASCOMP, and RWSIZE. When a specific mission profile is given to these programs, those will estimate the aircraft size, performance, rotor performance, component weight, and other aspects. Such results can become good sources for the supplemental analysis in terms of stability, handling qualities, and cost. If the results do not satisfy the stability criteria or other constraints, additional sizing processes may be used to re-evaluate rotorcraft size based on the result from stability analysis. Trade-off study can be conducted by connecting disciplines, and it is an important advantage in a preliminary design study. In this paper among the existing rotorcraft design programs, an adequate program is selected for a baseline of the design framework, and modularization strategy will be applied and further improvements for each module be pursued.

선택적부호화를 위한 비트율 변환기 (A Bit-rate Converter for Selective Coding)

  • 이종배
    • 전자공학회논문지
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    • 제51권9호
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    • pp.229-237
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    • 2014
  • 본 논문에서는 H.264/AVC 표준 비트 스트림을 전술영상이나 멀티미디어 환경에 응용가능한 선택적 부호화를 위한 비트율 변환방안을 제시하였다. 전송채널은 응용분야에 따라 다양한 채널 용량을 갖고 있고, 따라서 컴퓨터에 저장된 비트스트림은 전송채널용량을 초과하지 않도록 적절히 비트율 변환이 이루어져야한다. 기 제공된 영상압축 비트스트림을 다른 비트율로 재변환하는 문제가 바로 비트율 변환이며, 본 논문에서는 새로운 비트율 변환방식을 제안하고자 한다. MPEG이나 H.264/AVC 압축 비트스트림을 이용하여 비트율을 변환하는 다양한 방식들이 여러 학자들에 의해 제시되었으며 실제로 많이 응용되고 있지만, 본 논문의 선택적 부호화 응용 분야에는 제대로 적용되지 않는다. 즉 프레임 내의 특정한 영역이 다른 부분보다 정보의 가치가 크고 따라서 이들 부분은 다른 부분에 비해 고화질로 재생되어야 하지만 기존의 방식으로는 이를 구현하기가 힘들다. 따라서 본 논문에서는 관심영역과 배경 간의 정보의 중요성을 고려하여 화질을 차별화하는 새로운 비트율 변환기를 제안하고자 한다.

H.264/AVC 복호기를 위한 효율적인 인트라 예측기 하드웨어 구조 (The Hardware Architecture of Efficient Intra Predictor for H.264/AVC Decoder)

  • 김옥;류광기
    • 대한전자공학회논문지SD
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    • 제47권5호
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    • pp.24-30
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    • 2010
  • 본 논문에서는 H.264/AVC에서 압축 성능을 높이기 위해 사용된 기법중 하나인 인트라 예측에 대해 기술하고 인트라 예측 모드 연산을 효율적으로 수행하기 위한 인트라 예측기의 구조를 제안한다. 제안하는 인트라 예측기는 공통 연산기, 전처리 연산기, 인트라 예측 컨트롤러, 내부 메모리, 레지스터 컨트롤러로 구성된다. 공통 연산기와 전처리 연산기를 사용하여 연산량을 줄이고, 내부 메모리와 레지스터를 사용하여 외부 메모리와의 접근을 최소화 하였다. 제안한 인트라 예측기는 Verilog-HDL을 이용하여 설계하였으며, YUV 파일을 부호화 한 테스트 벡터를 이용하여 검증하였다. 설계된 인트라 예측기는 주로 핸드폰과 같은 휴대용 단말기에 사용하는 베이스라인 프로파일에 속하며 영상크기는 $176{\times}144$ 픽셀이다. 제안한 인트라 예측기의 예측 수행 사이클의 비교 분석 결과 기존에 비해 평균 약 60%의 향상된 결과를 얻었다.

인지과제 수행시 배경 소음의 크기에 따른 생리적 반응차 (The role background noise intensity on Physiological activity during performance of mental task)

  • 손진훈;;민윤기;이경화;최상섭
    • 한국음향학회:학술대회논문집
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    • 한국음향학회 1999년도 학술발표대회 논문집 제18권 1호
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    • pp.269-273
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    • 1999
  • Combination of mental stress task with noise background is a traditional tool employed in psychophysiology. However, intensity of background noise is a factor affecting both performance on test and psychophysiological responses associated with stress evoked by mental load in noisy environment. In the current study on 7 subjects we analyzed the influence of white noise (WN) intensity (55, 70, and 85 dB[A] ) on psychophysiological responses during word recognition test performed on noise background. There were recorded following physiological variables: electrodermal activity (EDA) , namely, skin conductance level (SCL), skin conductance response (SCR) amplitude (SCR-A), rise time and total number of SCRs (N-SCR); cardiovascular activity, e.g., heart rate (HR), respiratory sinus arrhythmia (RSA) index, pulse transit time (PTT), finger pulse volume (PV), skin temperature (SKT) and respiratory activity, such as respiration rate (RESP-R) and inspiration wane amplitude (RESP-A) during baseline resting state and 40 s long performance on 3 similar Korean word recognition tests with different WN intensity (55, 70, and 85 dB). Electrodermal responses (SCR-A, SCL, N-SCR) demonstrated gradual increment with increased intensity of noise, and this increase of response magnitude with higher intensity of noise was typical also for r skin temperature (phasic SKT decrease) and pulse volume (phasic and tonic PV decrease). However, some cardiovascular and respiratory responses did not exhibit same tendency of gradual increase of reactivity , namely HR, as well as RESP-R and RESP-A showed decrement of response magnitudes. Important finding in terms of cardiovascular reactivity was that 55 and 70dB evoked similar profiles, while 85dB WN resulted in significantly different profile of reactions, suggesting that there exists a threshold level after which intensive auditory stimulation elicits psychophyslological responses pattern of different quality. There are discussed potential autonomic mechanism involved in mediation of observed physiological responses.

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코드 테이블 패턴 분석을 통한 저비용 H.264/AVC 엔트로피 코딩 유닛 설계 (Design of Low Cost H.264/AVC Entropy Coding Unit Using Code Table Pattern Analysis)

  • 송세현;김기철
    • 전기전자학회논문지
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    • 제17권3호
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    • pp.352-359
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    • 2013
  • 본 논문에서는 H.264/AVC 베이스라인 프로파일을 위한 엔트로피 코딩 유닛을 제안한다. 엔트로피 코딩에서는 매크로블록 부호화를 위해 코드 테이블들을 사용한다. 이 코드 테이블에 있는 코드워드들 간에는 일정한 패턴이 존재하는데, 본 논문에서는 코드워드의 패턴을 분석하여 하드웨어 비용을 줄였다. 제안하는 엔트로피 코딩 유닛은 Exp-Golomb 유닛과 CAVLC 유닛으로 구성된다. Exp-Golomb 유닛은 하나의 유닛에서 5가지 코드타입을 처리하고, 코드 패턴을 이용하여 두 개의 덧셈기만으로 복잡한 Exp-Golomb 연산을 처리 할 수 있다. 기존의 CAVLC 유닛은 큰 사이즈의 코드 테이블을 필요로 한다. 본 논문에서는 테이블에 차분 코드워드들을 저장하여 기존 방식대비 테이블 크기를 40% 이하로 줄인다. 엔트로피 코딩 유닛은 생성된 코드워드들이 MSB에 코드값 0이 분포되는 패턴을 이용하여 쉬프터 사이즈를 대폭 줄였다.

H.264/SVC 복호기 C-Model 시뮬레이터 개발 (Development of C-Model Simulator for H.264/SVC Decoder)

  • 정차근
    • 한국콘텐츠학회논문지
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    • 제9권3호
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    • pp.9-19
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    • 2009
  • 본 논문에서는 최근 국제표준화가 이루어진 H.264/SVC 복호기 SoC 칩 개발을 위한 새로운 하드웨어 구조를 제안하고, 최적인 회로개발을 지원하기 위한 C-모델 시뮬레이터를 개발한다. 제안된 SVC 복호기는 표준규격의 기능들을 최적으로 처리하기 위한 하드웨어 엔진과 핵심 프로세서를 이용한 소프트웨어 등으로 구성되어 있어 기존의 임베디드 시스템으로 간단히 구현할 수 있다. 본 논문에서 제안한 복호기의 C-모델 시뮬레이터는 SVC의 스케일러블 베이스라인 프로파일을 기반으로 복잡도 감소를 위하여 B-픽처 구조를 사용하지 않는 IPPP 구조에 의한 스케일러블 만을 고려함으로서 칩 설계의 실용성을 증가시켰다. 하드웨어 구조와 C-모델 시뮬레이터의 유효성을 검증하기 위해 제안한 H.264/SVC 호기 시스템에 대한 결과를 제시한다.

응급 수부 미세수술 후 통증, 기분 및 외상 후 위기 정도의 변화양상 (Changes in Pain, Mood and Posttrauma Risk Level of Patients with Acute Hand Microsurgery)

  • 김민숙;윤순영;소희영
    • 재활간호학회지
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    • 제13권1호
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    • pp.44-52
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    • 2010
  • Purpose: The purposes of this study were to explore changes in pain, mood and the level of posttrauma risk for 2 weeks after acute hand microsurgery and determine predictors of pain 2-week after microsurgery. Method: Using a sample of 84 patients with hand microsurgery, pain, mood, and posttrauma risk were measured by the Brief Pain Inventory-Korea, the modified Profile of mood states, and the Posttrauma risk checklist at 1-day, 1-week and 2-week post-microsurgery. Repeated measures ANOVA and Multiple regression analysis were conducted to evaluate changes in pain, mood, and posttrauma risk over time after the surgery and determine predictors of pain 2-week after the surgery. Results: Pain significantly decreased (F=63.22, p<.001), mood significantly improved (F=41.04, p<.001) 2 weeks after microsurgery and interestingly, posttrauma risk significantly decreased from baseline to 1-week microsurgery but increased at 2-week after microsurgery (F=24.66, p<.001). Approximately 57% of the variance of pain 2-week post-microsurgery was explained by pain at 1-week post-microsurgery, mood and the numbers of injured fingers. Conclusion: The findings suggest the pain control for 1week after acute surgery being critical and posttrauma rehabilitation of injured finger being necessary. Developing nursing interventions is urgently needed to help individuals with impending hand microsurgery.

A novel schedule of accelerated partial breast radiation using intensity-modulated radiation therapy in elderly patients: survival and toxicity analysis of a prospective clinical trial

  • Sayan, Mutlay;Wilson, Karen;Nelson, Carl;Gagne, Havaleh;Rubin, Deborah;Heimann, Ruth
    • Radiation Oncology Journal
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    • 제35권1호
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    • pp.32-38
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    • 2017
  • Purpose: Several accelerated partial breast radiation (APBR) techniques have been investigated in patients with early-stage breast cancer (BC); however, the optimal treatment delivery techniques remain unclear. We evaluated the feasibility and toxicity of APBR delivered using intensity-modulated radiation therapy (IMRT) in elderly patients with stage I BC, using a novel fractionation schedule. Materials and Methods: Forty-two patients aged ${\geq}65$ years, with stage I BC who underwent breast conserving surgery were enrolled in a phase I/II study evaluating APBR using IMRT. Forty eligible patients received 40 Gy in 4 Gy daily fractions. Patients were assessed for treatment related toxicities, and cosmesis, before APBR, during, and after completion of the treatment. Results: The median age was 73 years, median tumor size 0.8 cm and the median follow-up was 54 months. The 5-year locoregional control was 97.5% and overall survival 90%. Erythema and skin pigmentation was the most common acute adverse event, reported by 27 patients (69%). Twenty-six patients (65%) reported mild pain, rated 1-4/10. This improved at last follow-up to only 2 (15%). Overall the patient and physician reported worst late toxicities were lower than the baseline and at last follow-up, patients and physicians rated cosmesis as excellent/good in 93% and 86 %, respectively. Conclusion: In this prospective trial, we observed an excellent rate of tumor control with daily APBR. The acceptable toxicity profile and cosmetic results of this study support the use of IMRT planned APBR with daily schedule in elderly patients with early stage BC.

자연산 문치가자미 (Limanda yokohamae)의 난소 발달에 따른 혈중 성호르몬과 난황단백전구체 농도 변동 (Plasma Sex Steroid Hormone and Vitellogenin Profiles during Ovarian Development of the Wild Marbled Sole (Limanda yokohamae))

  • 김대중;안철민;민광식
    • 한국수산과학회지
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    • 제39권5호
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    • pp.391-397
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    • 2006
  • This study correlated changes in estradiol-l7$\beta$ ($E_2$), testosterone (T), 17$\alpha$,20-dihydroxy-4-pregnen-3-one (DHP), and vitellogenin (VTG) levels with changes in the gonadosomatic index (GSI) and ovarian histology during the annual reproductive cycle of the wild marbled sole, Limanda yokohamae. Synchronous oocyte development occurs in this fish. Ovary maturity was classified into four periods, based on histological observations: the spawning (December to February), post-spawning (February to April), recovery (May to August), and vitellogenic (September to November) periods. Seasonal changes in the GSI were inversely correlated with water temperatures and reflected the degree of ovarian maturity. Plasma VTG levels were correlated with changes in the GSI, which increased from September to a peak in January, and levels remained comparatively high until February. Estradiol-17$\beta$ was at baseline levels (<0.11 ng/mL) during the spring and summer, and peaked rapidly (1.55$\pm$0.445 ng/mL) from October to January. Plasma T and DHP levels had a similar profile; they rose markedly during the spawning period and remained low (or were not detectable) from spring through autumn. These data indicate that changes in plsama steroid hormones and VTG levels are correlated with the annual ovarian activity of the marbled sole. Based on these results and published reports, it appears that in this species DHP is the most important maturation-inducing steroid and that T is also related to final maturation.