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Removing Baseline Drift from ECG Signal Using Smoothing Spline and Morphology Operation (평활화 스플라인 연산과 형태학 연산을 이용한 기저선 변동 잡음 제거)

  • Back, Seung-Gwan;Choi, Chang-Hoon;Kim, Jeong-Hong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.42 no.1
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    • pp.162-171
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    • 2017
  • Low frequency noise components causes the baseline drift in the ECG signals. In this paper, a morphological operation and smoothing spline technique are used for ECG signal processing in order to accomplish baseline correction. Removing the baseline drift from ECG signal using morphology operation, the feature of original signal may be distorted. To resolve this distortion problem, we applied a smoothing spline operation after morphology operation. In order to compare with existing morphology operation method for baseline correction, we apply proposed method to ECG data in MIT/BIH database. Compared to other existing method, our proposed method achieved low data distortion on the original signal.

Development and Testing of Day Care Program for Demented Elders (주간보호센터 중심의 재가 치매노인을 위한 프로그램의 개발 및 효과 검증 연구)

  • Lim, Young-Mi;Jeong, Bok-Hee
    • Journal of Korean Public Health Nursing
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    • v.19 no.2
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    • pp.371-381
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    • 2005
  • Purpose: The purpose of the study was to develop the day care program for the demented elders and to determine the effects of multiple activity therapies on the physical, emotional, cognitive, social function and physiological indicators of dementia elders in day care center. Method: A total of 13 elders with mild dementia in the data care center were participated. Manual and guideline of data care program was developed. Data care program was composed of movement/exercise, foot massage, music therapy, horticultural therapy, and art therapy. Data care program was performed by trained intervener for 32 weeks. Instruments were physical functioning such as hand grip strength., vital capacity, chiar stand test, sit and reach test, one leg standing, Berg' Balance scale, 6m Walk Velocity, stair climb, ADL, GDS-K, MMSE-K, Integrative Social Functioning Scale, cortisol, Ig A and Ig G. These were measured at the baseline, 16-week, and 32-week post-intervention by the trained nurses. Data were analyzed as Wilcoxon signed rank test. Results: For Hand grip, balance, and vital capacity, there was a significant difference between baseline and 16-week post-intervention(p<.05). For one leg standing, 6m velocity, there was a significant difference between 16-week post-intervention and 32-week post-intervention(p<.05). For Stair climb, there was a significant difference between baseline and 32-week post-intervention(p<.05). For depression and social functioning, there was no significant difference among baseline, 16-week, and 32-week post-intervention. For cognitive functioning, there was a significant difference between baseline and 32-week post intervention(p<.05). There was a significant difference of cortisol, and Ig G between baseline and 32-week post-intervention(p<.05). Conclusion: It would appear that physical fitness, functional performance, ADL, depression, social and cognitive functioning, and physiological indicator of community dwelling elders with dementia can be improved through day care program using multiple stimuli.

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Clinical Effects of Korean Red Ginseng on Attention Deficit Hyperactivity Disorder in Children: An Observational Study

  • Lee, Suk-Hwa;Park, Woo-Sung;Lim, Myung-Ho
    • Journal of Ginseng Research
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    • v.35 no.2
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    • pp.226-234
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    • 2011
  • We investigated the clinical effects of Korean red ginseng on attention deficit hyperactivity disorder (ADHD) in children. Eighteen subjects aged between 6 and 14 diagnosed with ADHD based on the Diagnostic and Statistical Manual of Mental Disorders, fourth edition diagnosis criteria were enrolled. Korean red ginseng (Panax ginseng) at 1,000 mg b.i.d. was administered to the subjects for 8 weeks. Eighteen children completed the questionnaire and clinical assessment by visiting the hospital at baseline, then in the first, fourth and eighth weeks. Clinical assessments were performed by using the ADHD Diagnostic System (ADS, a computerized attention assessment program), the abbreviated Conners' rating scale in addition to psychiatric interviews. After 8 weeks, significant differences were found in the omisssion errors of ADS ($78.56{\pm}43.33$ at baseline, $55.17{\pm}21.44$ at 8 weeks, p<0.023), Conners ADHD Rating Scale ($13.78{\pm}6.32$ at baseline, $9.50{\pm}4.80$ at 8 weeks, p<0.042) and Spielberger State Anxiety Scale ($30.94{\pm}6.25$ at baseline, $28.83{\pm}6.23$ at 8 weeks, p<0.024). In the Korean Personality Inventory for Children, a significant reduction of score was found in the physical development scale ($56.44{\pm}9.63$ at baseline, $50.94{\pm}8.91$ at 8 weeks, p<0.017) and social dysfunction scale ($56.33{\pm}6.82$ at baseline, $51.94{\pm}7.13$ at 8 weeks, p<0.025). These results suggest that Korean red ginseng may be effective in improving inattentiveness in ADHD children, but it remains uncertain if it improves the general severity of ADHD, depression, anxiety personality and behavioral changes.

Impact of Tropospheric Modeling Schemes into Accuracy of Estimated Ellipsoidal Heights by GPS Baseline Processing: Experimental Analysis and Results (GPS 기선해석에 의한 타원체고 추정에서 대류권 오차 보정기법이 정확도에 미치는 영향에 관한 실험적 분석)

  • Lee, Hungkyu
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.36 no.4
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    • pp.245-254
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    • 2018
  • Impact of tropospheric correction techniques on accuracy of the GPS (Global Positioning System) derived ellipsoidal heights has been experimentally assessed in this paper. To this end, 247 baselines were constructed from a total of 88 CORS (Continuously Operating Reference Stations) in Korea. The GPS measurements for seven days, acquired from the so-called integrated GNSS (Global Navigation Satellite Systems) data center via internet connection, have been processed by two baseline processing software packages with an application of the empirical models, such as Hopfield, modified Hopfield and Saastamoinen, and the estimation techniques based on the DD (Double-Differenced) measurements and the PPP (Precise Point Positioning) technique; hence a total number of the baseline processed and tested was 8,645. Accuracy and precision of the estimated heights from the various correction schemes were analyzed about baseline lengths and height differences of the testing baselines. Details of these results are summarized with a view to hopefully providing an overall guideline of a suitable selection of the modeling scheme with respect to processing conditions, such as the baseline length and the height differences.

Minimizing Algorithm of Baseline Wander for ECG Signal using Morphology-pair (Morphology-pair를 이용한 심전도 신호의 기저선 변동 잡음 제거 알고리즘)

  • Kim, Sung-Wan;Kim, Se-Yun;Kim, Tae-Hun;Choi, Byung-Jae;Park, Kil-Houm
    • Journal of the Korean Institute of Intelligent Systems
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    • v.20 no.4
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    • pp.574-579
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    • 2010
  • The baseline wander is most fatal noise, because it obstructs reliable diagnosis of cardiac disorder. Thus, in this paper, the morphology-pair is proposed for estimation of baseline wander except P, T-wave and QRS-complex. Proposed Morphology-pair is able to except P, R, T-wave which have characteristics of local maxima. Likewise Q, S-wave such as local minima are excepted by proposed Morphology-pair. The final baseline wander eliminated ECG signal is deducted by subtraction of original ECG and estimated baseline wander. The experimental results based on the MIT/BIH database show that the proposed algorithms produce promising results.

A Method of Calculating Baseline Productivity by Reflecting Construction Project Data Characteristics (건설 프로젝트 데이터 특성을 반영한 기준생산성 산정 방법)

  • Kim Eunseo;Kim Junyoung;Joo Seonu;Ahn Changbum;Park Moonseo
    • Korean Journal of Construction Engineering and Management
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    • v.24 no.3
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    • pp.3-11
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    • 2023
  • This research examines the need for a quantitative and objective method of calculating baseline productivity in the construction industry, which is known for its high volatility in performance and productivity. The existing literature's baseline productivity calculation methods rely heavily on subjective criteria, limiting their effectiveness. Additionally, data collection methods such as the "Five-minute Rating" are costly and time-consuming, making it challenging to collect detailed data at construction sites. To address these issues, this study proposes an objective baseline calculation method using unimpacted productivity BP, a work check sheet to systematically record detailed data, and a data collection and utilization process that minimizes cost and time requirements. This paper also suggests using unimpacted productivity BP and comparative analysis to address the objectivity and reliability issues of existing baseline productivity calculation methods.

Effect of Whole Body Vibration Training on Proprioception and Tactile in Spastic Cerebral Palsy (전신진동 자극 훈련이 경직형 뇌성마비 아동의 고유수용감각 및 촉각에 미치는 영향)

  • Yun, Hye-Lyeong;Lee, Eun-Ju
    • PNF and Movement
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    • v.20 no.1
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    • pp.103-113
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    • 2022
  • Purpose: The purpose of this study was to investigate the effects of whole-body vibration stimulation on proprioception and tactile in patients with spastic cerebral palsy. Methods: This study was conducted on 9 children diagnosed with spastic cerebral palsy. Of the single case study methods, the ABAB design was employed in this study. Out of a 12-week study period, three weeks were allocated to each of two baseline periods and two intervention periods. The exercise was performed twice a week for 30 minutes. A general trunk stabilization exercise was performed during the baseline period and a trunk stabilization exercise accompanied with whole-body vibration was performed during the intervention period. Evaluation was performed five times in total: before the experiment, after baseline 1, after intervention 1, after baseline 2, and after intervention 2. To determine the effect of the exercise method, a skin sensory evaluation tool (monofilament kit) and a trunk proprioception sensor (digital dual inclinometer) were used. To compare the effects of the exercises at baseline and after intervention, an analysis of variance on repeated measures (repeated ANOVA) was performed to analyze the data. Results: The results showed that there were statistically significant increases from baseline in the means of proprioception and tactile during the intervention period with whole-body vibration (p <.05). Conclusion: Whole-body vibration can be proposed as an effective intervention method for improving the proprioception and tactile in children with spastic cerebral palsy, and this exercise method is expected to be actively used in clinical practice.

Predicting Prognosis in Patients with First Episode Psychosis Using Mismatch Negativity : A 1 Year Follow-up Study (초발 정신증 환자에서 Mismatch Negativity를 이용한 1년 간의 예후 예측 연구)

  • Jang, Moonyoung;Kim, Minah;Lee, Tak Hyung;Kwon, Jun Soo
    • Korean Journal of Schizophrenia Research
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    • v.20 no.1
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    • pp.15-22
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    • 2017
  • Objectives : It has been shown that early intervention is crucial for favorable outcome in patients with schizophrenia. However, development of biomarkers for predicting prognosis of psychotic disorder still requires more research. In this study, we aimed to investigate whether baseline mismatch negativity (MMN) predict prognosis in patients with first episode psychosis (FEP). Methods : Twenty-four patients with FEP and matched healthy controls (HCs) were examined with MMN at baseline, and their clinical status were re-assessed after 1 year. Repeated-measures analysis of variance was performed to compare baseline MMN between the two groups. Multiple regression analysis was used to identify factors predicting prognosis in FEP patients during the follow-up period. Results : MMN amplitudes at baseline were significantly reduced in patients with FEP compared to healthy controls. In the multiple regression analysis, baseline MMN amplitude significantly predicted later improvement of performances on digit span and delayed recall of California Verbal Learning Test. However, baseline MMN did not predicted improvement of clinical symptoms. Conclusion : These results indicate that MMN may be a possible predictor of improvement in cognitive functioning in patients with FEP. Future study with larger sample and longer follow-up period would be needed to confirm the findings of the current study.

Changes in SARS-CoV-2 antibody titers 6 months after the booster dose of BNT162b2 COVID-19 vaccine among health care workers

  • Takeshi Mochizuki;Takaki Hori;Koichiro Yano;Katsunori Ikari;Ken Okazaki
    • Clinical and Experimental Vaccine Research
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    • v.12 no.2
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    • pp.116-120
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    • 2023
  • Purpose: In Japan, the data on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody titers after the booster dose of the coronavirus disease 2019 (COVID-19) vaccine are insufficient. The aim of this study is to evaluate changes in SARS-CoV-2 antibody titers before, 1, 3, and 6 months after the booster dose of the BNT162b2 COVID-19 vaccine among health care workers. Materials and Methods: A total of 268 participants who received the booster dose of the BNT162b2 vaccine were analyzed. SARS-CoV-2 antibody titers were measured before (baseline) and at 1, 3, and 6 months after the booster dose. Factors associated with changes in SARS-CoV-2 antibody titers at 1, 3, and 6 months were analyzed. Cutoff values at baseline were calculated to prevent infection of the omicron variant of COVID-19. Results: The SARS-CoV-2 antibody titers at baseline, and 1, 3, and 6 months were 1,018.3 AU/mL, 21,396.5 AU/mL, 13,704.6 AU/mL, and 8,155.6 AU/mL, respectively. Factors associated with changes in SARS-CoV-2 antibody titers at 1 month were age and SARS-CoV-2 antibody titers at baseline, whereas changes in SARS-CoV-2 antibody titers at 3 and 6 months were associated with the SARS-CoV-2 antibody titers at 1 month. The cutoff values of the SARS-CoV-2 antibody titers at baseline were 515.4 AU/mL and 13,602.7 AU/mL at baseline and 1 month after the booster dose, respectively. Conclusion: This study showed that SARS-CoV-2 antibody titers increase rapidly at 1 month after the booster dose of the BNT162b2 vaccine and begin to decrease from 1 to 6 months. Hence, another booster may be needed as soon as possible to prevent infection.

Trapezoidal Cyclic Voltammetry as a Baseline for Determining Reverse Peak Current from Cyclic Voltammograms

  • Carla B. Emiliano;Chrystian de O. Bellin;Mauro C. Lopes
    • Journal of Electrochemical Science and Technology
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    • v.15 no.3
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    • pp.405-413
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    • 2024
  • Several techniques for determining the reverse peak current from a cyclic voltammogram (CV) for a reversible system are described in the literature: CV itself as a baseline with long switching potential (Eλ) that serves as a baseline for other CVs, Nicholson equation that uses CV parameters to calculation reverse peak current and linear extrapolation of the current obtained at the switching potential. All methods either present experimental difficulties or large errors in the peak current determination. The paper demonstrates, both theoretically and experimentally, that trapezoidal cyclic voltammetry (TCV) can be used as a baseline to determine anodic peak current (iap) with high accuracy and with a switching potential shorter than that used by CV, as long as Eλ is at least 130 mV away from the cathodic peak. Beyond this value of switching potential the electroactive specie is completely depleted from the electrode surface. Using TCV with Eλ = 0.34 V and a switching time (tλ) of 240 s as a baseline, the determination of the reverse peak current presents a deviation from the expected value of less than 1% for most of the CVs studied (except cases when Eλ is close to the direct potential peak). This result presents better accuracy than the Nicholson equation and the linear extrapolation of the current measured at the switching potential, in addition to presenting a smaller error than that obtained in the acquisition of the experimental current. Furthermore, determining the reverse peak current by extrapolating the linear fit of iap vs. ${\sqrt[1/]{t_{\lambda}}}$ to infinite time gave a reasonable approximation to the expected value. Experiments with aqueous potassium hexacyanoferrate (II) and ferrocene in acetonitrile confirmed the theoretical predictions.