• 한국식품영양과학회지
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• 제29권1호
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• pp.120-127
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• 2000

Deep-fat frying is a common cooking practice. There has been considerable concern regarding the mutagenic and carcinogenic potential of thermally oxidized oils. Studies on deep-fried foods so far have revealed not much on the mutagenicity of the oils in the foods. Therefore, in the present study, it was attempted to investigate the mutagenicity ofthe thermally oxidized safflower oil. Oil was heated in a home-fryer at a temperature of 180$\pm$3$^{\circ}C$ for 48 hours. Oil samples were taken at 0, 8, 16, 24, 32, 40 and 48 hours of heating, respectively. Each sample was used to study the changes in peroxide value (POV), acid value (AV), iodine value (IV), conjugated dienoic acid (CDA) content, %, and fatty acid composition. Another series of samples were fractionated into non-polar and polar fractions by column chromatography. The mutagenicity of the samples taken from the thermally oxidized oils, as well as the non-polar and polar fractions of the thermally oxidized oils, was investigated with the Ames test. The Ames test was carried out with and without metabolic activation. Bacterial tester strains used in the present study were the histidine auxotrophic strains of Salmonella typhimurium TA100, TA1535 and TA102 were used for the detection of base pair mutations, and TA98 and TA1537 for frame shift mutations. Each series of samples was dissolved in tetraphydrofuran (inhibitor-free) and tested at doses ranging from 0.05 to 5 mg/plate. None of the oil samples taken during the 48 hour oxidation period showed any mugagenic activity. This was the case, even after the activaton with 59 mix. Also, none of the polar and non-polar fractions showed any mutagenic activity on all the strains tested.

• 한국통신학회논문지
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• 제36권2C호
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• pp.86-92
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• 2011

본 논문에서는 공간 다중화 방식과 적응형 빔 형성 기법을 결합한 다중 안테나 시스템에 대한 하향 링크 성능이 다루어진다. 이 결합 기법은 IEEE 802.16e 표준에 기반한 한국형 직교 주파수 분할 다중 접속 표준인 와이브로 시스템에 적용되었다. 성능 분석은 고정 소수점 모의실험 테스트 장비 및 컴퓨터 모의실험을 사용하여 수행되었다. 실험결과는 와이브로 시스템에 다중 입출력과 적응형 빔형성 기법이 결합되어 적용될 경우 기존의 단순한 다중 입출력 방식만 사용할 때보다 프레임 에러율 1%를 기준으로 QPSK에 대해서는 3dB, 16QAM에 대해서는 2.5dB의 신호 대 잡음비 이득을 제공함이 밝혀졌다. 고정 소수점 모의실험 테스트 장비 구현과 이를 이용한 실험을 통해, 다중 입출력과 적응형 빔형성의 결합 기법이 와이브로 기지국에 적용 가능함을 보여주였다.

• Genomics & Informatics
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• 제3권2호
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• pp.61-65
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• 2005

Comparing 231 genes on chimpanzee chromosome 22 with their orthologous on human chromosome 21, we have found that 15 orthologs have indels within their coding sequences. It was rather surprising that significant number of genes have changed by indel, despite the shorter time since their divergence and led us hypothesize that indels and structural changes may represent one of the major mechanism of proteome evolution in the higher primates. Human T-complex protein 10 like (TCP 10L) is a representative having indel within its coding sequence. Gene structure of human TCP10L compared with chimpanzee TCP10L gene showed 16 base pair difference in genomic DNA. As a result of the indel, frame shift mutation occurs in coding sequence (CDS) and human TCP10L express longer polypeptide of 21 amino acid residues than that of chimpanzee. Our prediction found that the indel may affect to dramatic change of secondary protein structure between human and chimpanzee TCP10L. Especially, the structural changes in the C-terminal region of TCP10L protein may affect on the interacting potential to other proteins rather than DNA binding function of the protein. Through these changes, TCP10L might influence gene expression profiles in liver and testis and subsequently influence the physiological changes required in primate evolution.

• 한국정보시스템학회지:정보시스템연구
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• 제17권3호
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• pp.205-233
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• 2008

This study suggests the dynamic value chain model, that will be able to not only show changing processes to organization's significant capital by integrating an individual, implicit, and explicit knowledge which affect organizational decision making, but also distinguish the key driver for raising organizational competitive power because it makes possible to analyze sensitivity of performance along with decision making alternatives and policy changes from dynamic view by connecting knowledge management capability, knowledge management activity, and relations with organizational performance with specific strategic map. Recently, a lot of organizations show interest in measuring and evaluating their performance synthetically. In organizations taking knowledge management, they introduce effective value chain model like a dynamic balanced scorecard (DBSC), and therefore they can reflect their knowledge management condition as well as show their changes by checking performance of established vision and strategy periodically. Furthermore, they can ask for their inner members' understanding and participation by communicating with and inspiring their members with awareness that members are one of their group, present a base of benchmarking, and offer significant information for later decision making. The BSC has been a successful framework for measuring an organization's performance in various perspectives through translating an organization's vision and strategy into an interrelated set of key performance indicators and specific actions. The BSC, while having significant strengths over traditional performance measurement methods, however, has its own limitations, due to its static nature, such as overlooking two-way causation between performance indicators and neglecting the impact of delayed feedback flowing from the adoption of new strategies or policy changes. To overcome these limitations, this study employs SD, a methodology for understanding complex systems where dynamic feedback among the interrelated system components significantly impact on the system outcomes. The SD simulation model in the form of DBSC would serve as a useful strategic teaming tool for facilitating an organization's communication process through various scenario analyses as well as predicting the dynamic behavior pattern of their key performance measures over a future time frame. For the demonstration purpose, this study applied the DBSC model to Prototype of Korea manufacturing and service firm.

• 전자공학회논문지CI
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• 제46권5호
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• pp.44-56
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• 2009

음성, 영상, 데이터와 같은 다양한 멀티미디어 서비스는 많은 대역폭과 실시간 처리가 필요하기 때문에 데이터의 지연과 손실에 민감한 특성을 가지고 있다. 따라서 네트워크의 흔잡 상황과 무선채널의 에러로 인한 데이터의 손실이 발생하여 사용자에게 QoS를 보장해주지 못하게 된다. 이러한 문제들을 해결하기 위해 멀티미디어 스트리밍 흐름에 속한 데이터 패킷의 중요도에 따른 차등적인 서비스로 멀티미디어의 품질을 개선하는 알고리즘의 연구가 필요하다. 본 논문에서는 무선손실이 발생했을 경우 IWFQ 알고리즘과 같이 동작하다가 멀티미디어 플로의 재생시간이 촉박할 때 우선적으로 채널을 할당하는 WMS-1(Wireless Multimedia Scheduling-1) 알고리즘과, 멀티미디어 플로에 우선권을 부여하고 프레임 유형에 따라 우선순위가 높은 프레임을 갖는 플로를 먼저 서비스하는 WMS-2(Wireless Multimedia Scheduling-2) 알고리즘을 제안한다. 기존의 알고리즘과의 비교를 통해 제안한 알고리즘의 멀티미디어 서비스 품질이 개선되었고 기지국의 큐 사이즈가 클수록 전체 서비스의 품질과 fairness가 향상된 것을 확인할 수 있었다.

• 한국조리학회지
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• 제7권2호
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• pp.157-179
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• 2001

Today the number or Chinese tourist visiting Korea is expected by 60% more than the number of them in the last year trunks to Chinese government's new policy on opening international trip. Overriding the striking perception of the new Chinese tourism market, the pre-research on this matter is not remarkable so far. It is expected that the theoretical base on the subject should be concrete. the purpose of the article is to provide the out-and-out information including the chinese market, the change of circumstance in China. Futhermore the study is proposed to offer valuable factor evaluating Chinese tourist to choose Korean restaurant and the relational consideration of the menu between estimation and satisfaction at the restaurant during their stay in Korea. In order to achieve the purpose of this paper, it is gore ahead of the literature review including the previous research on the menu of Hotel & Restaurant The major field research is to build a frame of the paper and present the model to release my humble theory. The 1imitation of the study was to make much of the literature basis due to insufficient previous research on the issue, The study would be framed into 6parts 1ike introduction, literature review, analysis of present coalition in China, major study including exploitative research, suggestion and dissuasions & conclusion. After the exploitative research, the study was approached to make findings through the questionnaires designed to find the relationship factor between chinese tourist's evaluation and satisfaction in the Hotel and Restaurant. According to the finding, chinese tourist tend to prefer the group ranging resonable-price and Japanese dishes to other group. They also interested the certain recipe including fish and vegetable. The evaluation menu is directly related to the satisfaction of Chinese tourist and we need a substantial managerial insight on it when the menu is already designed.

• 한국시뮬레이션학회논문지
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• 제26권2호
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• pp.9-17
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• 2017

현대사회의 다양한 분야에서는 복잡한 사회현상에 대하여 문제를 정의하고 문제해결책의 결과를 분석하는 과정으로 모델링 및 시뮬레이션을 활용하고 있다. 나날이 사회현상의 문제가 복잡해짐에 따라 요구되는 모델링 및 시뮬레이션 환경의 계산자원의 요구사항도 높아지고 있다. 이러한 요구사항을 수용하기 위해서 클라우드 서비스 등과 같이 컴퓨팅 자원을 유동적으로 사용할 수 있는 환경이 대두되었다. 본 연구에서는 이러한 컴퓨팅 자원 활용 시스템을 보다 효율적으로 활용할 수 있는 웹 기반 재구성이 가능한 시뮬레이션 실험 틀을 제안한다. 제안하는 시뮬레이션 실험 틀은 다양한 분산 컴퓨팅 환경을 지원할 수 있도록 프론트엔드(Front-end)에서 웹을 활용하여 시뮬레이션 모델의 재구성 시스템을 구축하고 백엔드(Back-end) 이산 사건 시뮬레이션의 실행을 담당하는 이산사건 시뮬레이션 실행단으로 구성된다. 본 연구는 사례연구를 통해 분산형 시뮬레이션 환경이 단일 시뮬레이션 환경보다 시간적 효율이 더 높음을 확인하였다.

• 생명과학회지
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• 제16권1호
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• pp.44-48
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• 2006

L-alanine의 산업적 생산을 위한 신규의 L-aspartate $\beta-carboxylase$ 유전자를 Enterococcus faecalis에서 검색하고 이를 대장균에 형질전환시켰다. E. faecalis 유래의 ADC유전자 는 1611 bp의 염기서열로 구성되어 있으며 형질전환된 대장균에서 59 KDa의 효소를 생산하며 L-aspartate $\beta-carboxylase$의 촉매활성을 나타내는 것을 확인하였다. 본 연구결과로 기능은 모르고 유전체 서열만 아는 균체에서 신규 효소를 개발하는 방법을 확립하였으며 저가의 aspartate를 이용한 고부가가치 L-alanine을 생산할 수 있는 신규효소를 개발할 수 있었다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2005년도 추계학술대회 논문집
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• pp.135-140
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• 2005

항만과 해역에 설치되는 수직벽의 일례로 육상 및 유입되는 오염수의 오염 유출 방지를 위한 차수기능을 갖는 차수벽과 교량이나 댐, 갑문 둥의 하천 또는 해양구조물을 축조하는 동안 물이 들어오는 것을 방지하기 위하여 임시로 설치되는 가물막이(cofferdam)벽 등이 있다 이들 차단벽의 구조역학적인 설계 인자 중 유입수 유동 특성과 설치 지역의 지반 특성이 중요한 의미를 가진다고 판단된다. 본 연구에서는 이러한 수직 차단벽 주위의 유체역학적 특성 파악의 일례로 수직벽의 하단에 틈새를 갖는 파공(perforation)이 발생하였을 때 이들 파공의 개도율 변화에 따른 유동특성을 고찰하는 하나의 방안으로 입자영상유속계(Particle Image Velocimetry)를 이용하여 수직벽 후류 특성을 실험적으로 고찰하였다.

• Environmental Analysis Health and Toxicology
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• 제26권
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• pp.5.1-5.11
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• 2011

Objectives: In order to identify the possibility of slender bitterling (SB) (Acheilognathus yamatsutae) being used as a test species for estrogenic endocrine disrupting chemicals (EEDCs), we carried out the cloning and sequence characterization of the estrogen receptor (ER). Methods: The ER from a slender bitterling was obtained by reverse transcriptase-polymerase chain reaction (RT-PCR), 5'- and 3'-rapid amplification of cDNA ends (5'-RACE and 3'-RACE) and T-vector cloning. The expression of ER mRNA was also analyzed in six tissues (brain, liver, kidney, gill, gonad, and intestines) by real-time PCR. Results: We obtained an ER from the slender bitterling. The SB ER cDNA was 2189 base pairs (bp) in length and contained a 1707 bp open reading frame that encoded 568 amino acid residues. The SB ER amino acid sequence clustered in a monophyletic group with the $ER{\alpha}$ of other fish, and was more closely related to zebrafish $ER{\alpha}$(88% identity) than to the $ER{\alpha}$ of other fish. The SB ER cDNA was divided into A/B, C, D, E and F domains. The SB ER has conserved important sequences for ER functions, such as the DNA binding domain (D domain), which are consistent with those of other teleosts. Conclusions: The ER of the slender bitterling could provide basic information in toxicological studies of EEDCs in the slender bitterling.