• Title/Summary/Keyword: Backbone model

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Characterization of the molten globule conformation of V26A ubiquitin by far-UV circular dichroic spectroscopy and amide hydrogen/deuterium exchange

  • Park, Soon-Ho
    • BMB Reports
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    • v.41 no.1
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    • pp.35-40
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    • 2008
  • The molten globular conformation of V26A ubiquitin (valine to alanine mutation at residue 26) was studied by nuclear magnetic resonance spectroscopy in conjunction with amide hydrogen/deuterium exchange. Most of the amide protons that are involved in the native secondary structures were observed to be protected in the molten globule state with the protection factors from 1.2 to 6.7. These protection factors are about 2 to 6 orders of magnitude smaller than those of the native state. These observations indicate that V26A molten globule has native-like backbone structure with marginal stability. The comparison of amide protection factors of V26A ubiquitin molten globule state with those of initial collapsed state of the wild type ubiquitin suggests that V26A ubiquitin molten globule state is located close to unfolded state in the folding reaction coordinate. It is considered that V26A ubiquitin molten globule is useful model to study early events in protein folding reaction.

Scalability of a Mobile Agents based Network Management Application

  • Rubinstein, M.G.;Duarte, O.C.M.B.;Pujolle, Guy
    • Journal of Communications and Networks
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    • v.5 no.3
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    • pp.240-248
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    • 2003
  • This paper analyzes mobile agent performance in network management compared to the client-server model used in the Simple Network Management Protocol (SNMP). Prototypes of an application that gathers MIB-II (Management Information Base-II) variables have been created and tested on a LAN. After acquiring implementation parameters related to network management and to the mobile agent infrastructure, simulation results have been obtained on large topologies similar in shape to the Internet. Response time results show that mobile agents perform better than SNMP when the number of managed elements ranges between two specific limits, an inferior bound and a superior one, determined by the number of messages that pass through a backbone and by the mobile agent size which grows along with MIB-II variables collected on network elements. The results also show that a significant improvement is achieved when the mobile agent returns or sends data to the management station after visiting a fixed number of nodes.

Mobile Multicast Mechanism in IP based-IMT Network Platform (IP기반-IMT 네트워크에서의 모바일 멀티캐스트 기법)

  • Yoon Young-Muk;Park Soo-Hyun
    • Proceedings of the Korea Society for Simulation Conference
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    • 2005.11a
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    • pp.3-7
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    • 2005
  • The structure of $IP^2$(IP based-IMT Network Platform) as ubiquitous platform is three-layered model : Middleware including NCPF(Network Control Platform) and SSPF(Service Support Platform), IP-BB(IP-Backbone), Access network including Sensor network. A mobility management(MM) architecture in NCPF is proposed for $IP^2$. It manages routing information and location information separately. The existing method of multicast control in $IP^2$ is Remote Subscription. But Remote Subscription has problem that should be reconstructed whole Multicast tree when sender moves. To solve this problem, we propose a way to put Multicast Manager in NCPF.

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A location tracking scheme using embedded-pager PCS terminals (Pager 내장형 PCS 단말기를 이용한 location tracking 기법)

  • 장경훈;심재정;박정식;김덕진
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.34S no.3
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    • pp.1-11
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    • 1997
  • Since the radio spectrum is limited, future wireless system will have micro cellular architecture in order to provide multimedia traffic services on personal communicatons network. The small coverage area of micro cellular systems results in frequent hadnoffs and location updates. We focuse on network load and terminal power due to frequent location updates and propose a location tracking scheme using embedded-pager PCS terminals. The proposed scheme is expected to minimize theconsumption of PCS terminal powr and improve the receiving rate of callee because of the power saving mechanism and the embedded-pager PCS terminal. This paper proposes signaling flows among the network elements for the proposed location tracking scheme. The signaling flows are accomodated to not only the existed network architectures but alsothe ATM backbone network arcitecture. To verify the signaling flows, we used petri-Net model. The resutls show that the signaling flows are suitable to our proposed location tracking scheme.

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DiffServ-Aware Pricing for Wireless Internet

  • Lee, Hoon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37 no.7B
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    • pp.550-564
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    • 2012
  • In this work we propose a new pricing scheme for the wireless Internet services over WiMAX system. First, let us review the characteristics of wireless network which is based on multi-hop relay WiMAX system. Next, we show why usage-based and QoS-aware pricing scheme is needed in the wireless Internet. After that, we propose a theoretical model for the price of multimedia services called a DAP (DiffServ-aware pricing) scheme for the WiMAX multimedia network which takes into account the consumed radio resource of WiMAX system as well as the supported QoS in the IP backbone network. Finally, we present explicit formulae for the packet price, price of consumed radio resource, and price of consumed bytes.

A Study on Modeling and Algorithm for WDM VWP Network Design (WDM VWP 네트워크 설계 모형 및 알고리즘 연구)

  • Lee, Hee-Sang;Hong, Sung-Pil;Song, Hae-Goo
    • Journal of Korean Institute of Industrial Engineers
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    • v.26 no.4
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    • pp.296-305
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    • 2000
  • Virtual wavelength path (VWP) is the optical path when a wavelength conversion is possible in a wavelength division multiplexing (WDM) network that is transmission infrastructure for the next generation high speed backbone networks. To achieve efficient design for VWP networks, we must consider VWP routing, wavelength assignment, and wavelength conversion while satisfying many technical constraints of the WDM networks. In this study we propose an integrated model for efficient VWP design in WDM networks. We also develope a 3-phase algorithm, each of which deals with routing, wavelength assignment and route and wavelength reassignment, respectively. In our computational experiments, phase 1 algorithm can solve the problem to the optimality for medium size test networks. Phase 2 algorithm is an efficient heuristic based on a reduced layered network and can give us an effective wavelength assignment. Finally, phase 3 algorithm reconfigure VWP routing and its wavelength assignment to concentrate wavelength conversion nodes in the suggested VWP network.

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A Study on the Determination of Optimum L.R.T Route from the Viewpoint of Revenue Maimization Principles (수익성을 감안한 경전철의 최적노선 결정방법에 관한 연구)

  • 원제무;박창호;이성모
    • Journal of Korean Society of Transportation
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    • v.12 no.3
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    • pp.29-47
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    • 1994
  • Although subway system continues to be the backbone of transportation systems in a city like Seoul, there will still be areas across the city where subway services are not avaliable. Interest has steadily grown to fill this missing routes in overall urban transportation system. Light Rail Transit (L.R.T) system has been recently thought to be an appropriate mode of transportation by businessmen, professionals and transportation industry. In this regards, the purpose of this study is to explore whether L.R.T can be a feasible form of urban rail mode in the context of Seoul. First, the study develops the mathematical models to derive optimum route networks and stations. Integer Programming is employed to determine whether alternative routes are financially viable from the viewpoint of revenue maximization principles. Second, mathematical models developed are applied to Yoido area in order to examine the validity of model structures. The models constructed turns out be capable of handling alternative routes and stations. Application of models are successfully carried out to derive financially feasible set of routes and stations.

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A Genetic Algorithm Approach to the Frequency Assignment Problem on VHF Network of SPIDER System

  • Kwon, O-Jeong
    • Journal of the military operations research society of Korea
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    • v.26 no.1
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    • pp.56-69
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    • 2000
  • A frequency assignment problem on time division duplex system is considered. Republic of Korea Army (ROKA) has been establishing an infrastructure of tactical communication (SPIDER) system for next generation and it will be a core network structure of system. VHF system is the backbone network of SPIDER, that performs transmission of data such as voice, text and images. So, it is a significant problem finding the frequency assignment with no interference under very restricted resource environment. With a given arbitrary configuration of communications network, we find a feasible solution that guarantees communication without interference between sites and relay stations. We formulate a frequency assignment problem as an Integer Programming model, which has NP-hard complexity. To find the assignment results within a reasonable time, we take a genetic algorithm approach which represents the solution structure with available frequency order, and develop a genetic operation strategies. Computational result shows that the network configuration of SPIDER can be solved efficiently within a very short time.

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Conformational Study of Y-Base in Yeast tRNA$^{phe}$

  • Moon, Myung-Jun;Jhon, Mu-Shik;Kang, Young-Kee
    • Bulletin of the Korean Chemical Society
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    • v.4 no.3
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    • pp.133-139
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    • 1983
  • To understand the importance of Y-base adjacent to the anticodon stabilizing codon-anticodon interaction, a study has been undertaken for the model compound involving the interaction between Y-base and anticodon as well as the participation of water molecule by calculating the conformational free energy using an empirical potential function. We restrict our analysis to sites directly associated with Y-base by varying only the backbone torsion angles of Y-base. The hydration and $Mg^{+2}$ binding effects on the conformational stability of Y-base are calculated and discussed. The free Y-base is proved to be less stable than the hydrated one. The free energy change due to the hydration of Y-base amounts to -119.5 kcal/mole, in which the conformational energy change is -142.4 kcal/mole and the configurational entropy change is -76.9 e. u. It is found that the water molecules bound to Y-base and $Mg^{+2}$ contribute to the conformation of Y-base dominantly.

GAN-based Color Palette Extraction System by Chroma Fine-tuning with Reinforcement Learning

  • Kim, Sanghyuk;Kang, Suk-Ju
    • Journal of Semiconductor Engineering
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    • v.2 no.1
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    • pp.125-129
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    • 2021
  • As the interest of deep learning, techniques to control the color of images in image processing field are evolving together. However, there is no clear standard for color, and it is not easy to find a way to represent only the color itself like the color-palette. In this paper, we propose a novel color palette extraction system by chroma fine-tuning with reinforcement learning. It helps to recognize the color combination to represent an input image. First, we use RGBY images to create feature maps by transferring the backbone network with well-trained model-weight which is verified at super resolution convolutional neural networks. Second, feature maps are trained to 3 fully connected layers for the color-palette generation with a generative adversarial network (GAN). Third, we use the reinforcement learning method which only changes chroma information of the GAN-output by slightly moving each Y component of YCbCr color gamut of pixel values up and down. The proposed method outperforms existing color palette extraction methods as given the accuracy of 0.9140.