• Journal of Microbiology and Biotechnology
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• v.17 no.7
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• pp.1059-1070
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• 2007

Prion diseases, often called transmissible spongiform encephalopathies (TSEs), are infectious diseases that accompany neurological dysfunctions in many mammalian hosts. Prion diseases include Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE, "mad cow disease") in cattle, scrapie in sheep, and chronic wasting disease (CWD) in deer and elks. The cause of these fatal diseases is a proteinaceous pathogen termed prion that lacks functional nucleic acids. As demonstrated in the BSE outbreak and its transmission to humans, the onset of disease is not limited to a certain species but can be transmissible from one host species to another. Such a striking nature of prions has generated huge concerns in public health and attracted serious attention in the scientific communities. To date, the potential transmission of prions to humans via foodborne infection and iatrogenic routes has not been alleviated. Rather, the possible transmission of human to human or cervids to human aggravates the terrifying situation across the globe. In this review, basic features about prion diseases including clinical and pathological characteristics, etiology, and transmission of diseases are described. Based on recently accumulated evidences, the molecular and biochemical aspects of prions, with an emphasis on the molecular interactions involved in prion conversion that is critical during prion replication and pathogenesis, are also addressed.

• Journal of the korean veterinary medical association
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• v.32 no.5
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• pp.285-316
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• 1996

소 해면형 뇌증(Bovine Spongiform Encephalpathy; BSE)이 처음 확인된 것은 1986년 11월이며, 영국에서의 최초발생을 시작으로 하여, 지난 10여년 동안 발생국가의 수는 다소 증가하고 있지만 전체적인 발생두수는 1993년을 정점으로하여 감소하는 추세를 보이고 있다. 아직까지도 확실한 병인체는 밝혀져 있지 않은 상태이며, 최초 확인당시 인체에의 감염 가능성은 없는 것으로 발표된 바 있으나, 지난 1996년 3월 20일, 영국정부 보건장관이 영구하원에서, 소 해면형 뇌증이 사람의 희귀한 뇌 질환인 크로이츠휄트-야곱병(CJD)의 새로운 스트레인(v-CJD)과 관련성이 있을 수 있다고 보고한 다음날, CNN 등 세계 각 매스컴을 통하여, '광우병 사람에게 전파될지도$\cdots$'(Mad cow illness may threaten humans)라는 제목으로 Top News로 보도되었으며, 수의학이나 의학적인 사실 확인의 여부를 떠나, 사회 경제적인 문제로 큰 놀라움과 많은 의문사항을 남겨둔 채, 국제적인 문제로 확대된 바있다. 본 편에서는, 소 해면형 뇌증 (BSE)과 관련, 영국의 광우병 파동이 일어난 지난 3월부터 지금까지 국내외 매스컴에 보도된 내용중 주요사항들을 스크랩하여 참고자료로 제공하고자 한다. 자료중에는 중복기사나 추측기사, 검증되지 아니한 오보, 지극히 개인적인 견해 등도 있을 수 있으며, 외신보도의 접수시간, 국내보도의 조간-석간, 지면구성, 수도권판과 지방판 등, 그리고 특히 병명이나 고유명사, 외래어 등의 전문용어 표기에 있어서 꼭 일치하지 아니하는 경우가 있을 수 있음을 참고로 하여야할 것이다.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7707-7711
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• 2015

A cross-sectional survey of 370 female teachers working at Governmental schools in Gaza city was conducted. Twenty four schools were selected randomly of all female schools of the city that included primary, preparatory and secondary. In each school all-female teachers aged 35-45 year were invited to fill out a self-administered questionnaire to investigate knowledge and behavior toward breast cancer screening. The survey revealed that more than 75% of women had never undergone clinical breast examination and 60% had never undergone mammography, whereas 62% performed breast self-examination (BSE). Women who performed BSE had significantly higher knowledge about breast cancer screening (P=0.001). Women attending CBE and mammography screening also had significantly higher knowledge (P=0.001). There were significant associations between the practices and presence of positive breast cancer family history (P=0.002) and the level of education of husbands (P=0.024). The oldest women demonstrated higher performance rates of screening methods than the youngest (P=0.001). Lack of breast screening knowledge was identified among more than one third of the women, and 24.6% of women did not know any screening method. About a half of women harboured misconceptions about breast cancer screening, including the belief that breast cancer not treatable. Women residing in Gaza city (P=0.00) and with husbands less educated were more likely to have a high level of misconceptions (P=0.01).

• Journal of the Mineralogical Society of Korea
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• v.12 no.2
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• pp.66-76
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• 1999

Intergrowth texture of biotite and chlorite crystals within an amphibolitic schist of the northwestern Okchon metamorphic belt was investigated using back-scattered electron (BSE) imaging and high-resolution transmission electron microscopy (HRTEM). BSE images show that thin chlorite and biotite packets are mixed along (001) plane to result in intergrowth texture. In addition, rutile particles of submicron size occur exclusively at the boundaries between biotite and chlorite stacks. HRTEM investigation and remnant biotite layers are closely associated with such boundaries, suggestinga possibility that chlorite layers were formed from biotite during retrograde metamorphic reaction. Such intepretation of the origin of intergrowth texture can be further supported biotite is approximately 2 w%, and that of chlorite usually lower than 0.2 wt%. Ti was apparently leached out during the alteratin of biotite to precipitate rutile particles at the such rutile particles could be an important indicator showing that the intergrowth texture of chlorite and biotite is originated by a retrograde metamorphism rather than by incomplete chlorite-to-biotite reaction during prograde metamorphism. Biotite crystals contain intercalated chlorite layers will result in somewhat high Mg and Al, and the use of such inhomogeneous biotite will result in impreciese geothermobarometric calculations.

• Journal of Home Health Care Nursing
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• v.28 no.2
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• pp.186-196
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• 2021

Purpose: Breast cancer is becoming increasingly prevalent among young Korean women. During pregnancy, women's concern regarding their breasts heightens. Thus, pregnancy provides a window of opportunity for breast cancer prevention and management along with antenatal care. This study developed and evaluated an integrated breast health program for pregnant women. Methods: This study employed a non-equivalent control group and non-synchronized design (22 experimental, 29 control). Women pregnant for over 28 weeks participated. The two-session integrated breast health program focused on breast management during breastfeeding and education about breast cancer prevention and early screening. Results: During the early postpartum period (within three months after the program), there were statistically significant differences in knowledge and attitude about breast cancer and breast self-examination before and after the program. There were also statistically significant differences in BSE at 6 and 12 months after the program and mammography at 12 months after the program. However, there were no statistically significant differences in clinical breast examination and breast ultrasonography at 6 and 12 months after the program. Conclusion: The integrated breast health management program was effective in increasing knowledge and improving attitudes regarding breast cancer, BSE, and early screening practices among pregnant women. Further studies should consider providing breast health programs differently for each phase of pregnancy and continuing the same after delivery.

• Journal of the korean veterinary medical association
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• v.32 no.3
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• pp.137-142
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• 1996

최근 소의 광우병 발생보고가 영국에서 16만여두 그리고 EU 14게국에서 약 150여 마리에 이르므로써 우산업분야에 미치는 심각한 경제적 여파와 인체에서의 Creutzfeldt-Jakob병과 어떤 연관성 논란으로 공중보건상 심각한 논쟁이 일고 있다. 본회 학술홍보 위원회에서는 이 질병에 관한 현재까지의 알려진 일반적인 지식을 정리하여 회원들에게 우선 소개하고자한다. 이 질병에 관한 보다 정리된 종합적인 내용은 수의과학연구소 해외전염병과에서 정리하여 다음호에 특집으로 소개할 것입니다.

• Monthly Korean Chicken
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• v.60 no.54 s.120
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• pp.94-95
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• 2005

2003년 12월 발생한 BSE의 영향으로 미국은 중요한 쇠고기 수출 시장을 잃었고, 2004년 초에 발생한 AI의 영향으로 가금류 수출에 제약을 받게 되었다. 또한 양돈사업의 높은 수익으로 인해 양돈업자들이 생산량을 늘려 돼지고기 공급량이 크게 늘었다. 그러나 육류 공급이 크게 증가했음에도 불구하고 2004년 소 가격은 2003년 수준보다 높았고, 육계가격은 기록적인 수준이었다. 2005년은 희망차게 시작되었다. 육류 단백질에 대한 수요가 크게 증가한 반면 육류 공급 증가는 수요에 미치지 못하여 가격은 높은 수준을 유지하고 있다. 또한 곡물가격은 적정한 수준을 유지하고, 여러 해 지속된 미 서부의 가뭄이 해소되고 있다. 생산자들은 수익향상에 따라 반응하고 있다. 돼지와 가금류 생산자들은 현재 이들 산업의 호전된 수익성에 반응하여 생산량을 완만하게 증가시킬 것으로 예상된다

• 동물약계
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• no.89
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• pp.4-6
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• 2003

[ $\cdot$ ]긴급 이사회 개최 $\cdot$동물약사감시 행정처분 결과 홍보 $\cdot$동물약품 마케팅반 교육 실시 $\cdot$돼지콜레라 예방약 추가 공급 $\cdot$농림부 및 검역원 인사 $\cdot$캐나다산 동물약품 BSE 증명서 제출 $\cdot$동물약품 부가가치세 영세율 적용 건의 $\cdot$2003 한국국제축산박람회 개최 안내 $\cdot$수입 원료 동물용의약품 관리 철저 $\cdot$동물용의약품등취급규칙 검토회의 참석 $\cdot$조합 2003년도 하반기 알찬거래선 선정 $\cdot$동물약품제조용 양허관세적용 유당 추가 배정 $\cdot$2002년도 세계 동물약품 시장 현황

• Feed Journal
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• v.2 no.5
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• pp.58-65
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• 2004

동물성사료는 가축의 도살과 축산물의 부위선별 작업과정에서 식용으로 사용되지 않은 것(동물성잔재물)을 랜더링 처리하면 동물성단백질사료로서 전환이 가능하여 사료원료로 이용되어 왔다. 그러나 최근 동물성잔재물을 이용한 재활용 물질인 육골분을 소에 급여하여 소해면상뇌증(BSE)과 관련성으로 영국 및 유럽 등 여러 국가에서 반추가축에 급여중단 등 가축의 사료로서 이용이 크게 제한되어 있을 뿐만 아니라 특정의 동물성잔재물은 재활용을 금지하고, 소각 후 매립하고 있다. (중략)

• Korean Journal of Adult Nursing
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• v.18 no.1
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• pp.146-156
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• 2006

Purpose: 1) to construct cohorts according to risk scores calculated with the Gail Breast Cancer Risk Assessment Tool (Gail et al., 1989) (Gail) and the Breast Cancer Risk Appraisal (Lee et al,. 2003) (Lee) 2) to identify the distribution of risk factors and preventive behavior stages between the cohorts 3) to identify abnormal breast conditions in risk cohort. Method: Using convenience sampling, 775 rural women were selected. Risk appraisal was scored using Gail and Lee. Preventive behavior stages for BSE (Breast self examination) and mammography were measured using 4 stages of the Transtheoretical Model (Prochaska & DiClemente, 1983). Results: 1) The risk cohort according to Gail was 12.3% (n=95), and Lee, 3.1% (n=24). 2) There were significant differences in the distribution of risk factors (age, family history, age at 1st live birth, age at menarche, number of breast biopsy, history of breast disease, and breast-feeding) between cohorts. 3) There was a significant difference in the distribution of the stage of BSE according to Lee. 4) Six women in the risk group detected masses or nodules and physician consultation and ultrasonography were recommended. Conclusion: On the basis of the constructed cohorts, further longitudinal studies of cohorts are recommended with interventions according to characteristics of cohorts.