• Economic and Environmental Geology
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• v.41 no.2
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• pp.225-242
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• 2008

The site effect for 23 broadband seismic stations in the southern Korean Peninsula was estimated by using the spectral ratio of coda waves. In principle, the site effect means the pure amplification below the station excluding effects of seismic source and attenuation in the wave transmission. However, the site effect determined in this study is equivalent with the relative site amplification factor to the mean amplification for all stations. A total of 500 three-component seismograms from 35 earthquakes, of which magnitude ranged from 2.5 to 5.1 occurred from January, 2001 to January, 2007 was used to obtain the site amplification factor. The site amplification factors were estimated for the frequency bands centered at 0.2, 0.5, 1, 2, 5, 10, 15, and 20 Hz. It was found that the factors for two horizontal components of transverse and radial records were concordant with each other in the all frequency bands. However, the factor for the vertical component was found to be systematically lower than those for two horizontal components. The factors obtained in the low frequency band below 2 Hz ranged from 0.5 to 1.5 in all seismic stations except for KMA and KIGAM stations in Bagryeongdo (BRD1 and BRD2) of which factor showed high value above 1.5. Some stations such as SEO, SNU, HKU, NPR, and GKPI showed high value above 1.5 in the high frequency band from 5 to 20 Hz. Especially, the factors of GKP1 station represented extremely high value ranging from 1.8 to 7.8. Also, the factors for stations of KWJ, SND, and ULJ showed low value below 0.5. The spatial distribution for the relative amplification factor represented a tendency of being approximately lower in north-eastern area than south-western area in the southern Korean Peninsula.

• Journal of fish pathology
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• v.18 no.1
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• pp.39-48
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• 2005

Pathogenicity of Vibrio tapetis, the causative bacterium of 'brown ring disease (BRD)' was evaluated in Manila clams (Ruditapes philippinarumi by artificially 0.1 $m\ell$ infection of $1.0\times10^5$cells and $1.0\times10^8$ cells at 20 $^{\circ}C$. A PCR assay based on 16S rRNA to detect the bacteria in clam tissues was established. Accumulative mortality of clams infected with $1.0\times10^7$cells and $1.0\times10^4$ cells per an individual of the bacteria was 67.5% and 7.5%, respectively. However, the deposit of brown pigment in the inner shells by accumulation of chonchiolin was not found. The bacteria were not be able to re-isolate from the infected clams by the conventional agar plate method but were easily detected by PCR assay established in this experiment. In clams artificially infected with 10 species of Vibrio, a 414bp for V. tapetis was detected in PCR assay. The specific band in the clams infected with $1.0\times10^4$cells per an individual of V. tapetis was detected only in gills one day after the infection but never be found in any tissues including gills three days after the infection. In the case of clams infected with $1.0\times10^8$cells per an individual of V. tapetis the specific band was detected in gills and intestine one day after the infection, in all tissues three days after the infection, and then in gills and adductor muscle nine days after the infection. The PCR assay was applied to detect V. tapetis in manila clam, surf clam (Mactra veneriformis), oyster (Crassostrea gigas) and Thomas' rapa whelk (Rapana venosa) taken from Taean and Gochang from April to July 2004. The infection rates were detected to 23.1% and 9.4% in the oyster and surf clam, while manila clam and Thomas' rapa whelk were not found.

• Journal of the Korea Safety Management & Science
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• v.6 no.1
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• pp.49-60
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• 2004

Industrial facilities are becoming more complex and various with rapidly developing technologies. A number of installations and equipments are increased to improve productivity, and they are operated under the condition of high temperature and pressure. They are continuously repaired, replaced or abolished because of the deterioration with time, but their repair and replacement are not easy for economical and environmental concerns. If possible, the deteriorating equipments should be inspected and repaired effectively considering the state of maintenance and preservation, economic efficiency, and safety. That's where RBI(Risk Based Inspection) fits in. Even if RBI technology has been known among specialists, there were no tools readily available and it was hard to practice and apply RBI in industrial inspection and safety management. In the development of the qualitative RBI, the overall algorithm adopted API-581 BRD. The qualitative RBI program was developed to search the appling process.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.11a
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• pp.185-185
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• 2002

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2003.05a
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• pp.80-80
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• 2003

• Journal of the Korean Society of Safety
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• v.21 no.3 s.75
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• pp.31-37
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• 2006

To apply easily the K-RBI program in domestic industries, an implemental procedure for K-RBI program was prepared. The K-RBI program had been developed, based on API-581 BRD. Therefore, through the usage of the developed K-RBI program and the implemental procedure, industries would have a benefit from reduced costs by modifying a frequency of an inspection efficiently. Also, the reliability of facilities would be maximized through improvement of an inspection method for facilities, considering its risk.

• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.439.2-439
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• 2004

Melatonin in mammals, produced by the pineal gland and elsewhere, has shown antioxidant and neuroprotective properties in neuronal cells. We investigated whether melatonin would increase newly-born cells (cell proliferation) in the dentate gyrus of maternally-separated rats. To examine the effect of melatonin on cell proliferation of the dentate gyrus in maternally-separated rats, 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry was performed.(omitted)

• The Journal of Korean Medicine
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• v.24 no.4
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• pp.127-135
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• 2003

Objectives : Intracerebral hemorrhage (ICH) is one of the most devastating types of stroke. The effect of acupuncture on the intrastriatal hemorrhage-induced neuronal cell death and cell proliferation in rats is examined. Methods : Cell death and cell proliferation in rats was investigated via terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay and immunohistochemistry for caspase-3 and 5-bromo-2'-deoxyuridine (BrdU). Results : Results showed that apoptotic cell death in the striatum and cell proliferation in the hippocampal dentate gyrus significantly increased following intrastriatal hemorrhage in rats, and that acupunctural treatment at the Zusanli acupoint suppressed the hemorrhage-induced increase in apoptosis in the striatum and cell proliferation in the dentate gyrus. Conclusions : It is suggested that acupunctural treatment, especially at the Zusanli acupoint, may aid recovery following central nervous system sequelae following ICH.

• 제어로봇시스템학회:학술대회논문집
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• 1994.10a
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• pp.385-389
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• 1994

So far many researches have studied to control a cart system with a pole on the top of itself (forwards we call it simply a cart system) which is movable only to the directions to which a cart moves, using neural networks and genetic algorithms. Especially which it wag solved by genetic algorithms, it was possible to control a cart system more robustly than ordinary methods using neural networks but it had problems too, i.e., the control time to be achieved was short and the processing time for it was long. However we could control a cart system using standard genetic algorithm longer than ordinary neural network methods (for example error backpropagation) and could see that robust control was possible. Computer simulation was performed through the personal computer and the results showed the possibility of real time control because the cpu time which was occupied by processes was relatively short.

• Biomedical Science Letters
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• v.12 no.4
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• pp.385-391
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• 2006

Heterotrimeric GTP binding proteins (G proteins) mediate signals generated by neurotransmitters and hormones Among G proteins, Go is found in a large quantity in brain and growth cone membranes of neurons. In spite of its abundance in neurons, the role of Go is not fully understood. In our previous study, we identified promyelocytic leukemia zinc finger protein (PLZF) as an interacting partner of alpha subunit of Go ($Go{\alpha}$) and confirmed their interaction employing several biochemical assays. To date, it is reported that PLZF functioned as a cell growth suppressor and a transcription repressor. To determine effect of $Go{\alpha}$ and PLZF interaction on the cellular function of PLZF, we performed luciferase reporter gene assay and BrdU incorporation assay. Co-expression of $Go{\alpha}$ and PLZF synergistically increased the effect of PLZF alone. These results suggest that $Go{\alpha}$ may act as cellular activator of PLZF. This novel feature of Go may provide insights into understanding diverse role of Go-coupled receptor as well as its cellular actions.