• 대학교육
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• 통권139호
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• pp.7-14
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• 2006

'분야별 특성화된 대학원 학과 육성을 통한 국제경쟁력 있는 석·박사급 인력 양성'을 목표로 하는 2단계 BK21 사업이 지난 1월 4일 사업 공고와 함께 막을 열었다. 2단계 BK21 사업을 통해 우리 대학이 인재 양성의 핵심기지가 되기를 기대한다.

• Journal of Microbiology and Biotechnology
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• 제33권11호
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• pp.1448-1456
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• 2023

A Gram-positive, non-motile, and non-spore-forming lactic acid bacterium, designated as BK2^T, was isolated from kimchi, a Korean traditional fermented vegetable food, and the taxonomic characteristics of strain BK2^T, along with strain LMG 11983, were analyzed. Both strains optimally grew at 30℃, pH 7.0, and 1.0% NaCl. Cells of both strains were heterofermentative and facultatively anaerobic rods, demonstrating negative reactions for catalase and oxidase. Major fatty acids (>10%) identified in both strains were C_18:1 ω9c, C_16:0, and summed feature 7 (comprising C_19:1 ω6c and/or C_19:1 ω7c). The genomic DNA G+C contents of both strains were 44.7 mol%. The 16S rRNA gene sequence similarity (99.9%), average nucleotide identity (ANI; 99.9%), and digital DNA-DNA hybridization (dDDH; 99.7%) value between strains BK2^T and LMG 11983 indicated that they are different strains of the same species. Strain BK2^T was most closely related to Weissella confusa JCM 1093^T and Weissella cibaria LMG 17699^T, with 100% and 99.4% 16S rRNA gene sequence similarities, respectively. However, based on the ANI and dDDH values (92.3% and 48.1% with W. confusa, and 78.4% and 23.5% with W. cibaria), it was evident that strain BK2^T represents a distinct species separate from W. confusa and W. cibaria. Based on phylogenetic, phenotypic, and chemotaxonomic features, strains BK2^T and LMG 11983 represent a novel species of the genus Weissella, for which the name Weissella fermenti sp. nov. is proposed. The type of strain is BK2^T (=KACC 22833^T=JCM 35750^T).

• 전자공학회논문지D
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• 제35D권1호
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• pp.84-93
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• 1998

Planar graded index optical waveguides have been formed by Ag$^{+}$ ion exchange in the BK7 optical glass. The experimental results of diffusion and modal characteristics of Ag$^{+}$-Na$^{+}$ exchanged BK7 glass waveguides are presented. Measurements of the mode indices have been measured. We found the relations between the process and device parameters such as the diffusion depth and the square root of the diffusion time, diffusion coefficient and diffusion temperature, and diffusion ion concentration and surface index change. A theoretical gaussian function refractive index profile matched best with the measured data for all the guided modes. The empirical relations between the process and the device parameters are derived and subsequently used to formulate a systematic procedure for fabricating singlemode and multimode waveguides.uides.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2007년도 제48회 학술심포지움 및 추계국제학술대회
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• pp.112.2-112.2
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• 2007

See Full Text

• 한국통신학회논문지
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• 제32권9C호
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• pp.861-866
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• 2007

본 논문은 가우시안 확률분포함수 (Gaussian Probability Distribution Function) 데이터 군집화를 위해 중심신경망 (Centroid Neural Network, CNN)에 Bhattacharyya 커널을 적용한 군집화 알고리즘 (Bhattacharyya Kernel based CNN, BK-CNN)을 제안한다. 제안된 BK-CNN은 무감독 알고리즘인 중심신경망을 기반으로 하고 있으며, 커널 방법을 이용하여 데이터를 특징공간에서 투영한다. 입력공간의 비선형 문제를 선형적으로 해결하기 위해 제안한 커널 방법인데, 확률분포 사이의 거리측정을 위해 Bhattacharyya 거리를 이용한 커널방법을 사용하였다. 제안된 BK-CNN을 영상데이터 분류의 문제에 적용했을 때, 제안된 BK-CNN 알고리즘이 Bhattacharyya 커널을 적용한 k-means, 자기조직지도(Self-Organizing Map)와 중심 신경망등의 기존 알고리즘보다 1.7% - 4.3%의 평균 분류정확도 향상을 가져옴을 확인할 수 있었다.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 춘계학술발표회
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• pp.264-265
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• 2011

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 추계학술발표회
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• pp.236-237
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• 2011

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 춘계학술발표회
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• pp.104-105
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• 2011

• Bulletin of the Korean Chemical Society
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• 제31권9호
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• pp.2514-2518
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• 2010

A very simple synthetic route of a novel SATE prodrug type of 6'-fluoro-6'-methyl-5'-noradeonosine carbocyclic nucleoside phosphonic acid is described. The key fluorinated alcohol intermediate 7 was prepared from the epoxide intermediate 6a via selective ring-opening of epoxide. Coupling of 7 with $N^6$-bis-Boc-adenine under a Mitsunobu reaction followed by phosphonation and deprotection afforded the carbocyclic phosphonic acid. The chemical stability of the bis(SATE) derivative 13 was measured at neutral (pH 7.2) and slightly acidic (Milli-Q water, pH 5.5) pH. The antiviral activity test of the SATE prodrug 13 and its parent nucleoside phosphonic acid 11 were evaluated against HIV-1.

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.2989-2992
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• 2009

An efficient synthetic route of novel 2′(${\alpha}$)-C-fluoro-2′(${\beta}$)-C-methyl carbocyclic nucleoside analogues is described. The key fluorinated intermediate 7 was prepared from the epoxide intermediate 5 via selective ring-opening of epoxide. Coupling of 7 with nucleosidic bases under the Mitsunobu reactions followed by deprotection afforded the target carbocyclic nucleoside analogues. The synthesized compounds were evaluated as inhibitors of the hepatitis C virus (HCV) in Huh-7 cell line in vitro.