• Bulletin of the Korean Chemical Society
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• v.32 no.7
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• pp.2187-2192
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• 2011

Hydrogen peroxide plays a key role as a second messenger in the normal cellular signaling but its overproduction has been implicated in various life-threatening diseases. Peroxalate chemiluminescence is the light emission from a three component reaction between peroxalate, hydrogen peroxide and fluorophores. It has proven great potential as a methodology to detect hydrogen peroxide in physiological environments because of its excellent sensitivity and specificity to hydrogen peroxide. We developed chemiluminescent micelles composed of amphiphilic polymers, peroxalate and fluorescent dyes to detect hydrogen peroxide at physiological concentrations. In this work, we studied the relationship between the chemiluminescence reactivity and stability of peroxalate by varying the substitutes on the aryl rings of peroxalate. Alkyl substitutes on the aryl ring of peroxalate increased the stability against water hydrolysis, but diminished the reactivity to hydrogen peroxide. Chemiluminescent micelles encapsulating diphenyl peroxalate showed significantly higher chemiluminescence intensity than the counterpart encapsulating dimethylphenyl or dipropylphenyl peroxalate. Diphenyl peroxalate-encapsulated micelles could detect hydrogen peroxide generated from macrophage cells stimulated by lipopolysaccharide (LPS) and image hydrogen peroxide generated during LPS-induced inflammatory responses in a mouse.

• Carbon letters
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• v.15 no.2
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• pp.136-141
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• 2014

Three dimensional self-assembled graphene hydrogels were easily fabricated by electron beam irradiation (EBI) using an aqueous solution of wool/poly(vinyl alcohol) and graphene oxide (GO). After exposure to various levels of EBI radiation, the highly porous, self-assembled, wool-based graphene hydrogels were characterized using scanning electron microscopy and Fourier-transform infrared spectroscopy; to determine the gel fraction, degree of swelling, gel strength, kinetics-of-swelling analyses and removal of hexavalent chromium (Cr(VI)) from the aqueous solution. X-ray diffraction results confirmed that EBI played a significantly important role in reducing GO to graphene. The adsorption equilibrium of Cr(VI) was reached within 80 min and the adsorption capacity was dramatically increased as the acidity of the initial solution was decreased from pH 5 to 2. Changes in ionic strength did not exert much effect on the adsorption behavior.

• Journal of the Korean Society of Safety
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• v.24 no.2
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• pp.48-54
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• 2009

Structures to support against slop failures or resist earth pressure like masonry retaining walls or retaining walls have continued to advance and evolve to new eco-friendly, easy-to-construct, crib retaining walls with varied forms and construction methods, meeting the needs of the times. Researches until now, however, have focused on the analyses of site displacement or stability of the whole site including structures like retaining walls, and thus, researches on rational design or method for stability analysis are lacking. Therefore, this study was conducted on a number of stability analyses, such as the visual power line or stability on sliding, being presented for bin walls, which enable vegetation to grow and were developed and applied in varied forms, meeting the development demands for eco-friendly retaining wall structures. This study compared the results of stability analyses, determined their feasibility, and evaluated their stability according to the height and facade slope of retaining walls. According to the results of this study, traditional masonry retaining wall analysis showed rather conservative stability evaluation results in the stability evaluation of bin walls, and the method using the visual power line seems to be objective because it produced similar results to the stability evaluation method on sliding or turnover.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.26 no.2
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• pp.223-229
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• 2017

Recently, robotic bin-picking tasks have drawn considerable attention, because flexibility is required in robotic assembly tasks. Generally, stereo camera systems have been used widely for robotic bin-picking, but these have two limitations: First, computational burden for solving correspondence problem on stereo images increases calculation time. Second, errors in image processing and camera calibration reduce accuracy. Moreover, the errors in robot kinematic parameters directly affect robot gripping. In this paper, we propose a method of correcting the bin-picking error by using trinocular vision system which consists of two stereo cameras andone hand-eye camera. First, the two stereo cameras, with wide viewing angle, measure object's pose roughly. Then, the 3rd hand-eye camera approaches the object, and corrects the previous measurement of the stereo camera system. Experimental results show usefulness of the proposed method.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.10
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• pp.1129-1136
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• 2020

This study investigates the factors influencing the usage of PSAU Mobile Application by the students at Prince Sattam bin Abdulaziz University (PSAU). This study used Technology Acceptance Model (TAM) as a framework to predict the factors influencing 67 students' usage of PSAU M-Application. The results of this study were consistent with the TAM framework in predicting the actual usage of the PSAU mobile application for academic activities. The results indicated a significantly positive association of the perceived ease-to-use with perceived usefulness, significantly positive associations of the perceived ease-to-use and the perceived usefulness with the attitude toward the usage of the PSAU's mobile application, a significantly positive association of the perceived usefulness with the behavioral intention toward the usage of the PSAU's mobile application, a significantly positive association of the students' attitude toward the usage of the PSAU's mobile application with the behavioral intention of using the application, and a significantly positive association of the behavioral intention with the actual usage of the PSAU's mobile application. The results of this study should be useful to educational policymakers at PSAU University and elsewhere, as there is an opportunity to enhance the existing technology or adopt new technologies for academic activities.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6432-6438
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• 2015

In this paper, we analyzed by measuring the temperature and humidity inside of the Feed Bin, NV, EA, SA, $SA{\cdot}EA$, by applying the ventilation system offers an efficient management of the operating direction. In the period the target is not input and feed period to make a change in the Feed Bin within the temperature and humidity of the outdoor air temperature and relative humidity compared to accept the ventilation system. Internal temperature over a comparison of the external temperature and the relative humidity is $SA{\cdot}EA$, internal humidity can verify the efficiency and NV, SA ventilation applied.

• Experimental and Molecular Medicine
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• v.50 no.12
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• pp.10.1-10.11
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• 2018

Cancer growth and progression are associated with immune suppression. Cancer cells have the ability to activate different immune checkpoint pathways that harbor immunosuppressive functions. Monoclonal antibodies that target immune checkpoints provided an immense breakthrough in cancer therapeutics. Among the immune checkpoint inhibitors, PD-1/PD-L1 and CTLA-4 inhibitors showed promising therapeutic outcomes, and some have been approved for certain cancer treatments, while others are under clinical trials. Recent reports have shown that patients with various malignancies benefit from immune checkpoint inhibitor treatment. However, mainstream initiation of immune checkpoint therapy to treat cancers is obstructed by the low response rate and immune-related adverse events in some cancer patients. This has given rise to the need for developing sets of biomarkers that predict the response to immune checkpoint blockade and immune-related adverse events. In this review, we discuss different predictive biomarkers for anti-PD-1/PD-L1 and anti-CTLA-4 inhibitors, including immune cells, PD-L1 overexpression, neoantigens, and genetic and epigenetic signatures. Potential approaches for further developing highly reliable predictive biomarkers should facilitate patient selection for and decision-making related to immune checkpoint inhibitor-based therapies.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.4
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• pp.400-406
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• 2019

We report a 12-month-old female infant who had a history of neonatal sepsis with liver micro-abscesses that resolved with intravenous antibiotics during neonatal period. During her neonatal admission period, no umbilical vein catheter was inserted. Also, she did not undergo any abdominal surgeries or had a postnatal history of necrotizing enterocolitis. However, the child developed upper gastrointestinal bleeding in form of hematemesis and melena secondary to esophageal varices at the age of 12 months with an extra-hepatic portal vein obstruction with cavernous transformation and portal hypertension subsequently. The child underwent a successful endoscopic injection sclerotherapy. She is now 20-month-old and has portal hypertension but otherwise asymptomatic. We are proposing the possibility of a delayed-onset portal hypertension as a complication of liver abscess and neonatal sepsis.

• Structural Monitoring and Maintenance
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• v.8 no.4
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• pp.361-378
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• 2021

While the pavement rating system is being utilized for periodic road condition assessment in the Eastern Region municipality of Saudi Arabia, the condition assessment is costly, time-consuming, and not comprehensive as only few parts of the road are randomly selected for the assessment. Thus, this study is aimed at developing a condition assessment model for a specific sample of a residential road network in Dammam City based on an individual road and a road network. The model was developed using the Analytical Hierarchy Process (AHP) according to the defect types and their levels of severity. The defects were arranged according to four categories: structure, construction, environmental, and miscellaneous, which was adopted from sewer condition coding systems. The developed model was validated by municipality experts and was adjudged to be acceptable and more economical compared to results from the Eastern region municipality (Saudi Arabia) model. The outcome of this paper can assist with the allocation of the government's budget for maintenance and capital programs across all Saudi municipalities through maintaining road infrastructure assets at the required level of services.

• Journal of the Korean Society for Precision Engineering
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• v.12 no.9
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• pp.156-166
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• 1995

This paper presents a bin picking method using a slit beam laser in which a robot recognizes all of the unoccluded objects from the top of jumbled objects, and picks them up one by one. Once those unoccluded objects are removed, newly developed unoccluded objects underneath are recognized and the same process is continued until the bin gets empty. To recognize unoccluded objects, a new algotithm to link edges on slices which are generated by the orthogonally mounted laser on the xy table is proposed. The edges on slices are partitioned and classified using convex and concave function with a distance parameter. The edge types on the neighborhood slices are compared, then the hamming distances among identical kinds of edges are extracted as the features of fuzzy membership function. The sugeno fuzzy integration about features is used to determine linked edges. Finally, the pick-up sequence based on MaxMin theory is determined to cause minimal disturbance to the pile. This proposed method may provide a solution to the automation of part handling in manufacturing environments such as in punch press operation or part assembly.