• Title/Summary/Keyword: BAS

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Trait individual difference of reinforcement-based decision criterial learning during episodic recognition judgments (일화 재인 기억에서 강화에 근거한 의사결정 준거 학습의 특성 개인차 연구)

  • Han, Sang-Hoon
    • Korean Journal of Cognitive Science
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    • v.20 no.3
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    • pp.357-381
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    • 2009
  • Although it is known that there are personality characteristic variances in the sensitivity to environmental feedback, the trait individual difference has scarcely been explored in the context of recognition memory decision. The present study investigated this issue by examining the relationship between the feedback-based adaptive flexibility of recognition criterion positioning and personality differences in general sensitivity to non-laboratory outcomes. Experiment 1 demonstrated that veridical feedback itself had little effect on the recognition decision criterion whereas Experiment 2 demonstrated that biased feedback manipulations selectively restricted to high confidence errors, induced shifts even in the overall Old/New category criterion. Critically, individual differences in stable personality characteristic linked to reward seeking(Behavioral Activation System-BAS) and anxiety avoidance (Behavioral Inhibition System-BIS) has been shown to predict the sensitivity of subjects to this form of feedback-induced criterion learning. This data further support the idea that incremental reinforcement-based learning mechanism not often considered important during explicit recognition decisions may play a key role in criterion setting.

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Correlations of Exogenous and Endogenous Components of Auditory ERPs to Psychometric Measures of Personality (청각 EPR의 내외생적 요소들과 성격의 상관에 관한 연구)

  • 박창범;이지영;지상은;박은혜;이영혁;김현택
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2002.11a
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    • pp.132-139
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    • 2002
  • 본 실험은 청각 사상관련전위(ERP)를 이용하여 다양한 성격 특질 모형들의 생물학적 근거와, 구조의 공통점과 차이점을 명확히 하기 위해서 설계되었다. 48명의 대학생 피험자들에게 4가지 성격 측정 검사(NEO-PI-R, EPQ-R, BIS/BAS 척도, IVE)를 시행하고, 이어 두 종류의 청각 자극 세트(50ms와 300ms)를 이용한 오드볼 과제를 통해 ERP를 측정하였다. 설문지 간의 상관과, 설문지와 ERP 내외생적 구성 요소 간의 상관, 그리고 그 상관의 두피 분포 양상을 통합적으로 고려하여 해석하였다. 각 성격 검사의 외향성 척도에 해당한다 할 수 있는 E, E, BAS-FUN은 양성 모두에서 높은 수준의 설문지 척도 간 정적 상관을 보였으나, 50ms 자극으로 유발된 P3 진폭은 E와 BAS-FUN에 대해서만 유의하게 높은 상관을 나타내었다. 이 결과는 Eysenck의 모델과 일견 일치하는 결과이지만, 그가 개발한 EPQ-R의 외향성 척도(E) 보다는 오히려 다른 척도들이 뇌파에 반영된 성격의 생물학적 기제를 측정하기 위한 적절한 도구일 수도 있음을 시사한다. 신경증적 경향성을 반영하는 N과 N 척도는 50ms 자극에 대한 여성 피험자의 N1, P2 진폭과 유의한 상관을 보였다. 그러나 이론적으로 두 척도에 등가적인 것으로 예상되었던 BIS 척도는 설문지 간 상관이나 ERP 요소와의 상관에서 모두 유의한 결과를 보이지 않았다. Eysenck가 성격의 세 번째 축(차원)으로 제시했던 P(정신병적 경향성) 역시 여성 피험자들에게서 두드러지는 설문지 간 상관을 보였으나, 300ms 자극에 대한 P2 진폭과의 정적인 상관은 양성을 합한 자료에서만 발견되었다. 여성의 상관 분포는 비록 통계적으로 유의한 수준에는 이르지 못하였으나, 양성 자료의 분포와 유사함이 확인되었다. 이 실험의 결과는 P3 진폭과 외향성 간의 부적인 상관 관계를 보고하였던 기존 연구들을 지지한다. 또한 본 실험에서 확인된 Eysenck 모델의 신경증적 경향성이나 정신병적 경향성이 ERP의 비교적 초기에 나타나는 외생적 구성 요소들(N1, P2)과의 상관 양상은, P3 요소에 집중하였던 기존 연구들이 외향성 이외의 차원으로 일관된 결과를 얻어내지 못했던 이유를 설명해줄 수 있을 것이다. 또한 성격 차원과 그것을 지표 하는 ERP 구성 요소 간의 관계를 해석할 때에 성별이나 유발 자극의 속성을 고려해야 함을 보여준다.

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A Novel Design of the Intelligent Fire Alarm Signaling System for the Integration of BAS by Developing Intelligent Control Modules with LonTalk Protocol of ANSI/EIA 709.1 (ANSI/EIA 709.1을 사용하는 지능형 제어모듈개발을 통한 화재 경보시스템의 새로운 설계방안)

  • Hong, Won-Pyo
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.17 no.4
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    • pp.64-73
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    • 2003
  • There are many economic and operational reasons to integrate fire alarm signaling system with other building automation system Integration of this requires open network with the standard communication protocol and careful design practices. The important point for this is also the development of intelligent control modules for replacing the conventional zone adapter in fire system. Therefore, this paper proposes an new conceptual design of the open distributed fire alarm signaling system for the integration of BAS and a new intelligent control modules with LonTalk protocol. Newly proposed additions to LonWorks network make it very well suited for integrating fire systems with other building automation systems. Additionally, it is very important that best design practices, test procedures and building codes need to be modernized to accommodate integrated building systems.

Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling

  • Xiao, Yongtao;Zhou, Kejun;Lu, Ying;Yan, Weihui;Cai, Wei;Wang, Ying
    • Experimental and Molecular Medicine
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    • v.50 no.11
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    • pp.14.1-14.14
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    • 2018
  • The link between antibiotic treatment and IF-associated liver disease (IFALD) is unclear. Here, we study the effect of antibiotic treatment on bile acid (BA) metabolism and investigate the involved mechanisms. The results showed that pediatric IF patients with cholestasis had a significantly lower abundance of BA-biotransforming bacteria than patients without cholestasis. In addition, the BA composition was altered in the serum, feces, and liver of pediatric IF patients with cholestasis, as reflected by the increased proportion of primary BAs. In the ileum, farnesoid X receptor (FXR) expression was reduced in patients with cholestasis. Correspondingly, the serum FGF19 levels decreased significantly in patients with cholestasis. In the liver, the expression of the rate-limiting enzyme in bile salt synthesis, cytochrome P450 7a1 (CYP7A1), increased noticeably in IF patients with cholestasis. In mice, we showed that oral antibiotics (gentamicin, GM or vancomycin, VCM) reduced colonic microbial diversity, with a decrease in both Gram-negative bacteria (GM affected Eubacterium and Bacteroides) and Gram-positive bacteria (VCM affected Clostridium, Bifidobacterium and Lactobacillus). Concomitantly, treatment with GM or VCM decreased secondary BAs in the colonic contents, with a simultaneous increase in primary BAs in plasma. Moreover, the changes in the colonic BA profile especially that of tauro-beta-muricholic acid ($T{\beta}MCA$), were predominantly associated with the inhibition of the FXR and further altered BA synthesis and transport. In conclusion, the administration of antibiotics significantly decreased the intestinal microbiota diversity and subsequently altered the BA composition. The alterations in BA composition contributed to cholestasis in IF patients by regulating FXR signaling.

The Target Detection and Classification Method Using SURF Feature Points and Image Displacement in Infrared Images (적외선 영상에서 변위추정 및 SURF 특징을 이용한 표적 탐지 분류 기법)

  • Kim, Jae-Hyup;Choi, Bong-Joon;Chun, Seung-Woo;Lee, Jong-Min;Moon, Young-Shik
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.11
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    • pp.43-52
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    • 2014
  • In this paper, we propose the target detection method using image displacement, and classification method using SURF(Speeded Up Robust Features) feature points and BAS(Beam Angle Statistics) in infrared images. The SURF method that is a typical correspondence matching method in the area of image processing has been widely used, because it is significantly faster than the SIFT(Scale Invariant Feature Transform) method, and produces a similar performance. In addition, in most SURF based object recognition method, it consists of feature point extraction and matching process. In proposed method, it detects the target area using the displacement, and target classification is performed by using the geometry of SURF feature points. The proposed method was applied to the unmanned target detection/recognition system. The experimental results in virtual images and real images, we have approximately 73~85% of the classification performance.

Comparison of laxative effects of fermented soybeans (Cheonggukjang) containing toxins and biogenic amines against loperamide-induced constipation mouse model

  • Kim, Ha-Rim;Park, In-Sun;Park, Su-Bin;Yang, Hee-Jong;Jeong, Do-Youn;Kim, Seon-Young
    • Nutrition Research and Practice
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    • v.16 no.4
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    • pp.435-449
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    • 2022
  • BACKGROUND/OBJECTIVES: Cheonggukjang is a traditional fermented soybean paste with significant health-promoting effects. On the other hand, there have been insufficient studies on the safety and efficacy of Cheonggukjang, which is produced using traditional methods containing toxins and biogenic amines (BAs). This study compared the laxative effect of Cheonggukjang, containing high or low levels of toxins and BAs (HTBC or LTBC) in a loperamide (Lop)-induced constipation mouse model. MATERIALS/METHODS: To induce constipation, Lop (5 mg/kg) was administered orally to ICR mice twice a day for 4 days, and the dose was increased to 8 mg/kg after a 3-day rest period. Cheonggukjang (500 mg/kg, HTBC, or LTBC respectively) was administered for four weeks before the Lop treatment. RESULTS: The number of stools, fecal weight, water contents, gastrointestinal transit, and histological alterations were recovered significantly in the HTBC or LTBC groups. HTBC and LTBC administration did not induce significant changes in body weight, dietary intake, and behavior. The opioid-receptor downstream signaling pathway in colon tissues was also evaluated. The c-Kit, stem cell kinase, and mitogen-activated protein kinases subfamilies, including extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinases, and p38, were all downregulated in the HTBC or LTBC-administered mice colon compared to the Lop group. CONCLUSION: These results show that Cheonggukjang, containing high levels of toxins and BAs, have a similar laxative effect in a mouse model of Lop-induced constipation.

Analysis of Cast Iron by Glow Discharge Emission Spectrometry (글로우 방전/방출분광분석법에 의한 주철시료의 분석)

  • Cho, K.H.;Woo, J.C.;Han, M.S.
    • Analytical Science and Technology
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    • v.6 no.3
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    • pp.297-305
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    • 1993
  • Generally, it is difficult to analyze cast iron samples with spark discharge emission spectrometry since the content of carbon in these samples is high as a few percent. The cast iron samples were analyzed with the developed glow discharge emission spectrometer composed of glow discharge emission source and polychromator. The discharge condition of glow discharge lamp(GDL) has been optimized by variation of Ar gas pressure, discharge voltage and discharge time. Under the optimum conditions obtained in this work, relationships between the measured emission intensities and concentration of two types of cast iron standard samples(BAS, LECO) were investigated. Most of elements(Mn, Si, P, S etc.) showed the good linearity in one calibration curve. And the carbon showed slightly the systematic difference according to the type of standard samples.

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