• Asian-Australasian Journal of Animal Sciences
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• 제16권4호
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• pp.570-574
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• 2003

This study investigate the effects of starter cultures on the color stability of Chinese-style sausage. The samples were inoculated with $10^7cfu\;g^{-1}$ meat of either Staphylococcus carnosus or Staphylococcus xylosus. After mixing, curing at either $4^{\circ}C$ or $20^{\circ}C$ for 20 h and then drying at $50^{\circ}C$ for 5 h, the samples were then either vacuum packed or hung at $4^{\circ}C$ and $25^{\circ}C$ (85% R. H.). The pH, nitrite content, nitrosyl pigment content, metmyoglobin and L-, a-, b- values were measured. The pH value still remained above 6.0 during storage. Nitrite residue of all samples decreased after storage at $25^{\circ}C$ for 7 days. The samples inoculated with S. carnosus and S. xylosus had higher nitrite content (20.9-34.7 ppm) than the control (p<0.05). Samples inoculated with S. carnosus and S. xylosus had higher nitrosyl pigment content and lower metmyoglobin content than those of the control. The L- and b- values of all samples decreased but the a- values increased with storage time. The result suggested that S. carnosus and S. xylosus starter cultures be used to improve color stability of Chinese-style sausage.

• 생명과학회지
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• 제26권1호
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• pp.23-33
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• 2016

Pexa-Vec (JX-594)은 암특이적 암용해 면역치료제인 백시니아 바이러스이다. 본 연구의 목적은 Pexa-Vec의 안정성을 극대화하기 위한 방법을 개발하는 것이다. 단기안정성 실험에서 바이러스의 활성은 4℃와 실온에서 감소하였으나, 초음파처리와 회전처리로 완전히 회복되었다. Pexa-Vec의 장기안정성 시험은 (A) 30 mM Tris/pH 7.6, (B) 30 mM Tris/pH 8.6, (C) 30 mM Tris/pH 7.6, 150 mM NaCl, 15% sucrose, (D) 30 mM Tris/pH 7.6, 15% sucrose, (E) 30 mM Tris/pH 8.6, 15% sucrose 조건 하에서 수행하였다. 제형 A는 4℃에서 4-8주 후, 실온에서 1주일 후에 2로그 이하로 바이러스활성이 감소되었다. 반면 제형 B의 경우 4℃와 실온에서 바이러스 활성이3일 후 감소되는 것으로 관찰되어 중성 산도가 바이러스 안정성을 유지하는데 필수적이다. 제형A에 15%의 슈크로즈 수크로오스를 추가했을 때(제형D), −20℃, 4℃와 실온에서 바이러스성 안정성이 크게 증가 하였고, 제형 E (pH 7.6)에서 다시 한번 확인되었다. 제형 D (pH 7.6)에 150 mM 염화나트륨을 추가한 제형 C에서 바이러스 안전성을 증가시키는 슈크로즈 수크로오스 효과를 더욱 향상시켜, 4℃와 실온에서 바이러스 활성이 각각 1.5년과 1-2주 동안 유지되는 결과를 보였다. 결론적으로, 우리는 제형C가 항암 백시니아 바이러스를 적절히 저장하기 위한 충분한 조건을 제공할 수 있다고 제안한다.

• Bulletin of the Korean Chemical Society
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• 제23권10호
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• pp.1425-1446
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• 2002

An efficient procedure for the synthesis of 6,7-dichloro-5,8-phthalazinedione (4) was developed in 49% overall yield via chloroxidation of 5,8-diaminophthalazine (8). And a series of its derivatives, 7-pyridinium-5,8-phthalazinedione-6-oxide (9), 6-chloro-7-phenylamino-5,8-phthalazinedione (10), 6,6-dimethoxy-6H-2,3,6b,11-tetraazabenzo[a]fluoren-5-one (11a), and 6,6-diethoxy-6H-2,3,6b,11-tetraazabenzo[a]fluoren-5-one (11b) have been synthesized.

• 대한기계학회논문집B
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• 제27권7호
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• pp.893-900
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• 2003

Numerical simulations of freely propagating flames burning stoichiometric C $H_4$/CHC1$_3$/ $O_2$/$N_2$ mixtures are performed at atmospheric pressure in order to understand the effect of the $O_2$ enrichment level and the CHC1$_3$/C $H_4$ molar ratio. A chemical kinetic mechanism is developed, which involves 69 gas-phase species and 379 forward and 364 backward reactions. The calculated flame speeds are compared with the experiments for the flames established at several CHC1$_3$/C $H_4$ molar ratio (R<1), the results of which is in excellent agreement. As a results of the increased $O_2$ enrichment level from 0.21 to 1, the flame speed and the temperature in the burned gas are increased. At high CHC1$_3$/C $H_4$ molar ratio two peak values appear on the $O_2$ consumption rate, which are affected by CC1$_2$＋ $O_2$$_{-}$>C1O+CC1O and H＋ $O_2$$_{-}$>O＋OH.＋OH.

• Journal of Magnetics
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• 제1권1호
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• pp.1-3
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• 1996

The $YBa_2Cu_3O_{7-x}$ structure has been fluorinated by a gas phase exchange technique. The ${^19}F$NMR (nuclear magnetic resonance) spin-lattice relaxation rate (1/T1) measurements on a fluorinated sample gave superconducting energy gap of $2\Delta=4.6kT_c$.

• Archives of Pharmacal Research
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• 제18권1호
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• pp.27-30
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• 1995

The Hantzsh reaction of 7-hydroxy-8-methoxy-2-oxo-2H-benzopyran-6-carboxaldehyde (1) with ethyl acetoacetate and ammonia yields the dihydropyridine derivative 2 together with the pyridine derivative 3 and the eight membred ring derivative 4. Reaction of 1 with ethyl cyanoacetate and malononitrile gives the iminodicoumarin derivatives 5 and 6 respectiely. The latter compound was reacted with butan-2-one and acetophenone to produce the Michael adduct 71, b and the 2-aminopyridine derivatives 8a, b.

• Bulletin of the Korean Chemical Society
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• 제35권4호
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• pp.1098-1104
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• 2014

New electron deficient acceptor-acceptor-acceptor type of monomer unit composed of weak electron accepting benzimidazole and relatively strong electron accepting benzothiadiazole derivatives namely 4,7-bis(6-bromo-1-(2-ethylhexyl)-1H-benzo[d]imidazol-2-yl)benzo[c][1,2,5]thiadiazole (BBB) was synthesized. The Stille polycondensation of the newly synthesized BBB monomer with electron donating 2,6-bis(trimethyltin)-4,8-bis(2-ethylhexyloxy)benzo[1,2-b:4,5-b']dithiophene (BDT) afforded donor-acceptor-acceptor-acceptor type of polymer namely 2,6-(4,8-bis(2-ethylhexyloxy)benzo[1,2-b:4,5-b']dithiophene)-alt-4,7-bis(1-(2-ethylhexyl)-1H-benzo[d]imidazol-2-yl)benzo[c][1,2,5]thiadiazole (PBDTBBB). The opto-electrical studies revealed that the absorption band of PBDTBBB appeared in the range of 300 nm-525 nm and its highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energy levels were positioned at -5.18 eV and -2.84 eV, respectively. The power conversion efficiency (PCE) of the polymer solar cell (PSC) prepared from PBDTBBB:PC71BM (1:2 wt %) blend was 1.90%.

• 한국식품영양과학회지
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• 제30권3호
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• pp.395-402
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• 2001

Bacillus subtilis 돌연변이주 중 ${\gamma}-GTP$활성이 높은 SM-2와 SM-10을 융합시켜 획득한 융합주 중 ${\gamma}-GTP$활성이 높은 융합주 FG-21의 배양적 특성을 조사하였다. 융합주 FG-21에 의한 ${\gamma}-GTP$의 생산은 1% glycerol, 1% peptone, 0.1% citric acid, 5 mM $K_2HPO_4$, 1 mM $FeCl_3$, 1 mM $MgCl_2$, 1 mM $NH_4Cl$, pH 7.0의 배지에 의해 $37^{\circ}C$에서 36시간 배양했을 때 621 U/mL으로 최대한 활성을 보였다. 융합주 FG-21이 생산한 biopolymer A가 단백질함량이 38.4%이고 B. subtilis K-1이 생산하는 biopolymer B의 단백질함량은 19.3%로 융합주 FG-21이 생산하는 Biopolymer A보다 함량이 낮았다. 융합주 FG-21의 biopolymer가 모균주의 biopolymer B보다 단백질함량이 높은 것은 상대적으로 높은 ${\gamma}-GTP$활성이 높아서 생성된 PGA가 levan보다 함량이 많기 때문인 것으로 사료된다. 총당함량은 biopolymer A가 58.5%, biopolymer B가 76.5%로 나타났다. 융합주 FG-21과 모균주가 생산하는 biopolymer의 단백질함량과 총당함량비는 융합주 FG-21이 생성한 biopolymer는 38 : 59. 모균주가 생산한 biopolymer B는 19 : 78의 비율이었고 HPLC 분석에 의한 biopolymer A와 B의 fructose함량은 각각 537.7 mg/g biopolymer, 764.4 mg/g biopolymer으로 나타났다. Biopolymer A와 B의 glutamic acid함량은 각각 163.7 mg/g, 94.3 mg/g이었다. Biopolymer A와 B의 fructose와 glutamic acid의 함량비는 각각 78 : 22, 89 : 11의 비로 함유되어 있었다. 따라서 융합주에 의해 생산된 biopolymer는 모균주보다 구성상태가 변화된 biopolymer를 생산한 것으로 판단되어 fusion과 같은 균주개량을 통하여 물질의 구성적, 물질적 변화된 biopolymer를 생산할 수 있을 것이라 사료된다.

• 치과방사선
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• 제15권1호
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• pp.13-20
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• 1985

The author obtained the oblique lateral trans cranial radiograms from 376 patients (114 of male, and 262 of female) with temporomandibular joint arthrosis. After tracing each film, the author analyzed the dimensional changes of the condylar heads with pain, clicking, mouth opening limitation, and masticatory difficulty respectively, which were the chief complaints of the TMJ arthrosis and compared these data with control group. The results were as follows; 1. There was a great predilection for occurrence of the TMJ arthrosis in female (262 cases) over male (114 cases). But there was no significant difference in ratio between the sexes on each symptom. In male, 60 patients (52.6%) had pain, 28 patients (24.6%) had clicking, 21 patients (18.4%) had mouth opening limitation, and 5 patients (4.4%) had masticatory difficulty. In female, 148 parients (56.5%) had pain, 57 patients (21.8%) had clicking, 47 patients (17.9%) had mouth opening limitation, and 10 patients (3.8%) had masticatory difficulty. 2. Examined controlled group, the author analyzed the dimension of W-W', 0-H, 0-A, 0-B on the right side first, and left side second. In male, the dimension of W-W' was 14.52㎜, 14.13㎜; 0-H was 13.92㎜, 13. 71㎜' 0-A was 8.91㎜, 9.0㎜ and 0-B was 8.67㎜, 8.78㎜. In female, W-W' was 13.77㎜, 13.51㎜; 0-H was 13.42㎜, 13.35㎜; 0-A was 8.92㎜, 9.01㎜; and 0-B was 8.59㎜, 8.80㎜. 3. W-W' and 0-H of the experimental group were distinctly lesser than the controlled group. Male with mouth opening limitation show the least (12.70㎜, 13.00㎜) on W-W', but both sexes with pain show the least on 0-H. There was no significant difference between experimental group with Clicking and controlled group on 0-H, 0-A, and 0-B. And also there was no difference on 0-B in patients with every symptom except masticatory difficulty. The dimensional changes of the condylar heads with those symptoms were as follows; a) In male patients, complaing of pain, W-W' of the right and left was 13.80㎜, 12.80㎜; 0-H was 13.10㎜, 12.90㎜; 0-A was 8.69㎜, 8.18㎜; 0-B was 8.33㎜, 8.42㎜. In female, W-W' was 13.01㎜, 12.90㎜; 0-H was 12.48㎜, 12.80㎜; 0-A was 8.60㎜, 8.49㎜; 0-B was 8.48㎜, 8.50㎜. b) In male patients with clicking, W-W' was 13.70㎜, 13.10㎜; 0-H was 13.90㎜, 13.10㎜; 0-A was 8.81㎜, 8.16㎜ 0-B was 8.34㎜, 8.25㎜. In female, W-W' was 13.10㎜, 13.50㎜; 0-H was 13.30㎜, 12.91㎜; 0-A was 8.95㎜, 8.49㎜; 0-B was 8.23㎜, 8.70㎜. c) In male patients with mouth opening limitation, W-W' was 12.70㎜, 13.00㎜; 0-H was 13.40㎜, 13.40㎜; 0-A was 8.37㎜, 8.48㎜; 0-B was 8.33㎜, 8.62㎜. In female, W-W' was 13.00㎜, 12.50㎜ 0-H was 12.90㎜, 13.10㎜; 0-A was 8.49㎜, 8.09㎜; 0-B was 8.77㎜, 8.01㎜. d) In male patients with masticatory difficulty, W-W' was 13.30㎜, 13.20㎜; 0-H was 13.40㎜, 12.60㎜; 0-A was 8.26㎜, 8.32㎜; 0-B was 7.80㎜, 8.20㎜. In female, W-W' was 12.30㎜, 12.00㎜; 0-H was 13.10㎜, 13.20㎜; 0-A was 8.68㎜, 7.95㎜; 0-B was 7.46㎜, 7.87㎜.

• 한국결정학회지
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• 제4권1호
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• pp.1-5
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• 1993

니클로사미드 일수화물의 결정구조는 흑연으로 단색화된 Mo-Ka 방사선을 사용하는 자동 CAD4 회절 기로 측정된 1976개의 독립반점을 이용하여 결정되었다. 결정계는 단사정계이며, 공간군은 P211c이고, 293k에서 단위세포 상수는 a=11.331(3), b=6.964 (2), c=7.347(4)A, p=98.20(3)°, Z=4이다. 구조는 ggg Parity군에 속하는 반불변수를 이용하는 직접법으로 해석하였으며, 완전행렬 최소자승법으로 정밀화하여 최종 신뢰도 R=0.046인 모형을 구하였다. 분자 모양은 ab평면상에 평행하게 놓이는 평면성 구조를 나타낸다.