• Asian-Australasian Journal of Animal Sciences
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• 제26권8호
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• pp.1152-1159
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• 2013

Four male lambs (Katahdin; average live weight $25.9{\pm}2.9$ kg) with "T" type cannulas in the rumen and proximal duodenum were used in a $4{\times}4$ Latin square experiment to evaluate the influence of supplemental dry distillers grain with solubles (DDGS) levels (0, 10, 20 and 30%, dry matter basis) in substitution for dry-rolled (DR) corn on characteristics of digestive function and digestible energy (DE) of diet. Treatments did not influence ruminal pH. Substitution of DR corn with DDGS increased ruminal neutral detergent fiber (NDF) digestion (quadratic effect, p<0.01), but decreased ruminal organic matter (OM) digestion (linear effect, p<0.01). Replacing corn with DDGS increased (linear, $p{\leq}0.02$) duodenal flow of lipids, NDF and feed N. But there were no treatment effects on flow to the small intestine of microbial nitrogen (MN) or microbial N efficiency. The estimated UIP value of DDGS was 44%. Postruminal digestion of OM, starch, lipids and nitrogen (N) were not affected by treatments. Total tract digestion of N increased (linear, p = 0.04) as the DDGS level increased, but DDGS substitution tended to decrease total tract digestion of OM (p = 0.06) and digestion of gross energy (p = 0.08). However, it did not affect the dietary digestible energy (DE, MJ/kg), reflecting the greater gross energy content of DDGS versus DR corn in the replacements. The comparative DE value of DDGS may be considered similar to the DE value of the DR corn it replaced up to 30% in the finishing diets fed to lambs.

• Asian-Australasian Journal of Animal Sciences
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• 제31권5호
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• pp.696-704
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• 2018

Objective: This study was conducted to evaluate various levels of milk by-product in weaning pig diet on growth performance, blood profiles, carcass characteristics and economic performance for weaning to finishing pigs. Methods: A total of 160 weaning pigs ([Yorkshire${\times}$Landrace]${\times}$Duroc), average $7.01{\pm}1.32kg$ body weight (BW), were allotted to four treatments by BW and sex in 10 replications with 4 pigs per pen in a randomized complete block design. Pigs were fed each treatment diet with various levels of milk by-product (Phase 1: 0%, 10%, 20%, and 30%, Phase 2: 0%, 5%, 10%, and 15%, respectively). During weaning period (0 to 5 week), weaning pigs were fed experimental diets and all pigs were fed the same commercial feed during growing-finishing period (6 to 14 week). Results: In the growth trial, BW, average daily gain (ADG), and average daily feed intake (ADFI) in the nursery period (5 weeks) increased as the milk by-product level in the diet increased (linear, p<0.05). Linear increases of pig BW with increasing the milk product levels were observed until late growing period (linear, p = 0.01). However, there were no significant differences in BW at the finishing periods, ADG, ADFI, and gain:feed ratio during the entire growing-finishing periods. The blood urea nitrogen concentration had no significant difference among dietary treatments. High inclusion level of milk by-product in weaner diet decreased crude protein (quadratic, p = 0.05) and crude ash (Linear, p = 0.05) of Longissimus muscle. In addition, cooking loss and water holding capacity increased with increasing milk product levels in the weaner diets (linear, p<0.01; p = 0.05). High milk by-product treatment had higher feed cost per weight gain compared to non-milk by-products treatment (linear, p = 0.01). Conclusion: Supplementation of 10% to 5% milk by-products in weaning pig diet had results equivalent to the 30% to 15% milk treatment and 0% milk by-product supplementation in the diet had no negative influence on growth performance of finishing pigs.

• Asian-Australasian Journal of Animal Sciences
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• 제19권11호
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• pp.1638-1642
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• 2006

An experiment was conducted to elucidate the effect of graded levels of vitamin $D_3$ in White Leghorn (WL) layer breeders on egg production, shell quality, hatchability of eggs and juvenile performance of offspring during their late laying period (72-88 wk). White Leghorn breeder females were randomly divided into 5 groups of 50 each and were housed in individual California cages in an open-side housing system. Considering birds in five cages as a replicate, 10 such replicates were randomly allotted to each treatment. A basal diet was formulated containing all the nutrients as recommended for WL layers except vitamin $D_3$, which served as control. Another, four diets were formulated by supplementing graded levels of feed grade crystalline cholecalciferol to the basal diet that contained 300, 600, 1,200 and 2,400 ICU of vitamin $D_3$ per kg. Each diet was offered ad libitum to one of the above five treatment groups. The egg production, egg weight, daily feed consumption and the feed intake per dozen eggs or kg egg mass of the birds fed diet without any supplemental vitamin $D_3$ was comparable with those of supplemental groups. Similarly, the level of vitamin in the diet did not have any effect on any of the above parameters. However, the specific gravity of eggs laid by the birds fed the diet without supplemental vitamin $D_3$ was comparable with either 600 or 2,400 ICU supplemental groups but significantly higher when compared to the 300 and 1,200 ICU groups. The egg -shell breaking strength was significantly lowered in the 600 ICU supplemental groups as compared to the strength of other dietary groups. The Haugh unit, egg shell weight, shell thickness, tibia breaking strength, bone ash and calcium content were not influenced by vitamin $D_3$ concentration in the diet. Serum Ca concentration was influenced by vitamin $D_3$ level in the diet. The serum Ca concentration of birds fed either control or the vitamin supplemented diet up to 1200 ICU/kg diet was comparable. However, increasing the concentration of vitamin $D_3$ to 2,400 ICU/kg diet significantly enhanced the concentration of Ca in the serum, which was significantly higher compared to other dietary groups. The serum concentration of P and protein, however, was not influenced by level of vitamin $D_3$ in the diet. Neither fertility nor hatchability was influenced by vitamin $D_3$ concentration in the diet. Feeding a vitamin $D_3$ deficient diet or supplementation of vitamin to hens did not have any influence on their progeny chicks. It can be concluded that dietary supplementation of vitamin $D_3$ may not be essential for optimum production, shell quality, hatchability, and juvenile performance of WL breeders during 72 to 88 weeks of age.

• Journal of Animal Science and Technology
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• 제59권7호
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• pp.19.1-19.10
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• 2017

Background: To reduce use of main feed ingredient like corn, soy bean meal (SBM) and wheat, alternative ingredients has been studied like copra meal (CM). Production amount of CM which has been high makes CM to be an alternative feed stuff. However, low digestibility on AA and low energy content by high fiber content can be an obstacle for using CM. This experiment was conducted to evaluate the effects of CM supplementation with ${\beta}$-mannanase on growth performance, blood profile, nutrient digestibility, pork quality and economic analysis in growing-finishing pigs. Methods: A total of 100 growing pigs ([Yorkshire ${\times}$ Landrace] ${\times}$ Duroc) averaging $31.22{\pm}2.04kg$ body weight were allotted to 5 different treatments by weight and sex in a randomized complete block (RCB) design in 5 replicate with 4 pigs per pen. Treatments were 1) Control (corn-SBM based diet + 0.1% of ${\beta}$-mannanase (800 IU)), 2) CM10 (10% copra meal + 0.1% ${\beta}$-mannanase (800 IU)), 3) CM15 (15% copra meal + 0.1% ${\beta}$-mannanase (800 IU)), 4) CM20 (20% copra meal + 0.1% ${\beta}$-mannanase (800 IU)) and 5) CM25 (25% copra meal + 0.1% ${\beta}$-mannanase (800 IU)). Four phase feeding program was used: growing I (week 1-3), growing II (week 4-6), finishing I (week 7-9) and finishing II (week 10-12). Results: In growth performance, there was no significant difference among treatments during whole experimental period. In growingI phase, G:F ratio tended to increase when CM was increased (P = 0.05), but ADG and ADFI tended to decrease in finishingII phase (linear, P = 0.08). Also, increasing CM reduced ADG (linear, P = 0.02) and feed efficiency (linear, P = 0.08) during the whole finishing period. In blood profiles, BUN was linearly increased as CM increased (linear, P = 0.02) at growingII period. In digestibility trial, there was no significant difference in dry matter, crude fat, crude ash and nitrogen digestibility. However, crude protein digestibility was decreased linearly (linear, P = 0.02). In economic analysis, feed cost per weight gain and total feed cost per pig were reduced in overall period when CM was provided by 25% (linear, P = 0.02). Conclusion: CM with 0.1% of ${\beta}$-mannanase (800 IU) could be supplemented instead of corn and SBM up to 25% without detrimental effects on growth performance and pork quality of growing-finishing pigs.

• 한국식품영양학회지
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• 제25권4호
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• pp.922-929
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• 2012

다시마 분말을 밀가루 중량에 대해서 3%, 5%, 7%와 9%의 비율로 첨가하여 제조한 스펀지 케이크의 물리적 관능적 특성을 검토해본 결과, 다시마 분말 첨가 스펀지 케이크의 수분함량은 첨가구간의 유의적 차이는 없었으며, 조단백질 함량은 대조구가 가장 낮았고, 다시마 분말 첨가량이 증가할수록 증가하였다. 조지방 함량은 대조구와 다시마 분말 첨가구 간의 유의적 차이가 없었다. 회분 함량은 대조구가 가장 낮은데 비해 다시마 분말 첨가량이 증가할수록 유의적으로 증가한 것을 볼 수 있었다. 다시마 분말 첨가 스펀지 케이크의 탄수화물 함량은 대조구와 첨가구 간의 유의적 차이는 없었다. 비중은 대조구가 가장 낮게 나타났으며, 대조구에 비해 다시마 분말 첨가군의 비중이 유의적으로 증가하는 것으로 나타났다. 굽기 손실은 대조구가 가장 낮았고, 9% 첨가구가 가장 높게 나타났으며, 반죽 수율은 대조구가 가장 높았고, 9% 첨가구가 가장 낮았다. 다시마 첨가에 의하여 케이크의 색은 다소 어둡고 푸른색을 띄는 변화를 보였다. 밝은 정도를 나타내는 L값은 대조군이 다른 첨가군들에 비해 유의적으로 높게 평가되었고, 다시마 첨가량이 증가할수록 유의적으로 감소하여 다시마 분말 9% 첨가구가 가장 어두운 색을 나타내었다(p<0.05). 적색도를 나타내는 a값도 다시마 분말 첨가량이 증가할수록 유의적으로 증가하였다. 황색도를 나타내는 b값은 다시마 분말 첨가량이 증가함에 따라 유의적으로 감소하였다(p<0.05). 다시마 분말 첨가량에 따른 스펀지 케이크의 texture 특성으로 경도(hardness), 탄력성(springiness), 응집성(cohesiveness), 점착성(gumminess), 씹힘성(chewiness), 회복탄력성(resilience)을 검토해본 결과, 3%, 5%와 7% 첨가구는 대조구와 비교하여 그 물리적 특성이 비슷하거나 큰 차이가 없었으나, 9% 첨가구의 경우 스펀지 케이크의 texture로서 바람직하지 않은 것으로 나타났다. 스펀지 케이크의 외관은 다시마 분말 첨가량이 증가할수록 부피와 높이가 감소하였으며, 가운데 부분이 약간 주저앉은 것을 확인할 수 있었다. 스펀지 케이크의 전반적 기호도, 색, 향기, 조직감, 맛에 대한 관능적 특성을 조사한 결과, 3%와 5% 첨가구에 대한 전반적 기호도와 맛에 대한 선호도가 높은 것으로 유의성(p<0.05) 있는 결과가 나타났다. 다시마 분말 첨가 스펀지 케이크의 개발 가능성 검토를 위해 다시마 분말을 다양한 수준으로 첨가한 케이크를 제조하여 물리적 관능적 특성을 검토해본 결과, 다시마 분말 3% 첨가 스펀지 케이크와 5% 첨가 스펀지 케이크가 물리적 특성과 관능적 특성을 모두 만족시킬 수 있는 첨가량임을 확인할 수 있었다.

• 한국식품과학회지
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• 제33권4호
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• pp.455-460
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• 2001

장기간 저장된 정부미의 품질을 개선하기 위하여 개발된 찹쌀가루 물을 이용한 청결미의 품질 평가를 실시하였다. 쌀의 수분 함량은 모두 약 14% 이상으로 수분 함량으로 인한 품질차이를 초래할 만큼의 차이가 없었으며 찹쌀가루 물로 세척한 청결미의 수분활성도는 일반 청결미보다 상대적으로 높았다. 동일한 정부미로 생산되었으나 찹쌀가루 물로 씻은 청결미가 단순히 물로만 세척된 청결미와 비교하여 단백질 함량이 상승되어 찹쌀 가루 물로부터 단백질이 첨가된 것으로 생각된다. 쌀가루의 호화 양상은 물로 씻은 청결미는 햅쌀과 비교하여 저장된 쌀의 특성을 나타내었으며, 찹쌀가루 물로 씻은 청결미는 세척과정에서 유입된 찹쌀가루에 의하여 찹쌀의 호화 양상으로 인하여 물로 씻은 청결미에 비하여 호화 점성이 낮아지고 햅쌀에 가까운 전분의 호화특성을 나타내었다. 색도계로 측정된 쌀의 명도와 백색도와 황색도는 모두 물로 씻은 청결미가 가장 높았다. 조리된 밥은 쌀보다 세척에 따른 색의 차이가 더욱 뚜렷이 나타나서, 일반 청결미의 황색도가 가장 높게 나타났다. 밥의 색깔 차이는 육안으로 더욱 뚜렷이 구별되어, 밥의 관능 검사 결과 일반 청결미와 찹쌀가루 물로 씻은 청결미간에 유의적인 차이에 의하여 찹쌀가루 물로 씻은 청결미의 황색도가 감소된 것을 확인 할 수 있었다. 햅쌀로 조리된 밥은 색과 외관 및 물성과 맛 및 전체 적인 선호도가 가장 좋으나, 찹쌀가루 물로 씻은 청결미로 조리된 밥이 물로 씻은 청결미로 조리된 밥에 비하여 관능 검사의 모든 항목에서 유의적으로 향상되었음을 확인할 수 있었으므로, 찹쌀가루 물을 이용하여 오래도록 저장된 쌀을 청결미로 개발하는 방법은 정부미로 조리된 밥의 식미감을 향상시키기 위한 효과적인 방법으로 생각된다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.19-29
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• 1996

The neurological manifestations of AIDS include dementia, encountered even in the absence of opportunistic superinfection or malignancy. The AIDS Dementia Complex appears to be associated with several neuropathological abnormalities, including astrogliosis and neuronal injury or loss. How can HIV-1 result in neuronal damage if neurons themselves are only rarely, if ever, infected by the vitus\ulcorner In vitro experiments from several different laboratiories have lent support to the existence of HIV- and immune-related toxins. In one recently defined pathway to neuronal injury, HIV-infected macrophages/microglia as well as macrophages activated by HIV-1 envelope protein gp120 appear to secrete excitants/neurotoxins. These substances may include arachidonic acid, platelet-activating factor, free radicals (NO - and O$_2$), glutamate, quinolinate, cysteine, cytokines (TNF-${\alpha}$, IL1-B, IL-6), and as yet unidentified factors emanating from stimulated macrophages and possibly reactive astrocytes. A final common pathway for newonal suscepubility appears to be operative, similar to that observed in stroke, trauma, epilepsy, and several neurodegenerative diseases, including Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis. This mechanism involves excessive activation of N-methyl-D-aspartate (NMDA) receptor-operated channels, with resultant excessive influx of Ca$\^$2+/ leading to neuronal damage, and thus offers hope for future pharmacological intervention. This chapter reviews two clinically-tolerated NMDA antagonists, memantine and nitroglycerin; (ⅰ) Memantine is an open-channel blocker of the NMDA-associated ion channel and a close congener of the anti-viral and anti-parkinsonian drug amantadine. Memantine blocks the effects of escalating levels of excitotoxins to a greater degree than lower (piysiological) levels of these excitatory amino acids, thus sparing to some extent normal neuronal function. (ⅱ) Niuoglycerin acts at a redox modulatory site of the NMDA receptor/complex to downregulate its activity. The neuroprotective action of nitroglycerin at this site is mediated by n chemical species related to nitric oxide, but in a higher oxidation state, resulting in transfer of an NO group to a critical cysteine on the NMDA receptor. Because of the clinical safety of these drugs, they have the potential for trials in humans. As the structural basis for redox modulation is further elucidated, it may become possible to design even better redox reactive reagents of chinical value. To this end, redox modulatory sites of NMDA receptors have begun to be characterized at a molecular level using site-directed mutagenesis of recombinant subunits (NMDAR1, NMDAR2A-D). Two types of redox modulation can be distinguished. The first type gives rise to a persistent change in the functional activity of the receptor, and we have identified two cysteine residues on the NMDARI subunit (#744 and #798) that are responsible for this action. A second site, presumably also a cysteine(s) because <1 mM N-ethylmaleimide can block its effect in native neurons, underlies the other, more transient redox action. It appears to be at this, as yet unidentified, site on the NMDA receptor that the NO group acts, at least in recombinant receptors.

• Asian-Australasian Journal of Animal Sciences
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• 제28권9호
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• pp.1345-1353
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• 2015

This study was conducted to investigate the influence of dietary rapeseed meal (RSM) on growth performance, blood profiles, nutrient digestibility and economic benefit of growing-finishing pigs. A total of 120 growing pigs ($[Yorkshire{\times}Landrace]{\times}Duroc$) with an initial body weight (BW) $29.94{\pm}0.06kg$ were used in this experiment. Pigs were randomly allotted into 1 of 5 treatments in a randomized complete block design and 6 replicates with 4 pigs per pen. Treatments were divided by dietary RSM supplementation levels (0%, 3%, 6%, 9%, or 12%) in growing-finishing diets. A linear decrease (p<0.05) of BW and average daily gain (ADG) were observed at 13th wk of finishing and overall periods of pigs. Additionally, gain-to-feed ratio (G/F) tended to decrease by dietary RSM supplementation in growing-finishing diets (linear, p = 0.07 and quadratic, p = 0.08). Concentrations of serum triiodothyronine and thyroxine were not influenced by dietary RSM treatments whereas thyroid gland and liver weight were increased at 13th wk of finishing period (linear, p<0.05; p<0.01) by increasing dietary RSM supplementation level. In blood profiles, serum total cholesterol and low density lipoprotein cholesterol concentrations were not differed by dietary treatments at 13th wk of finishing period whereas concentration of serum high density lipoprotein cholesterol was affected by the supplementation level of RSM, resulting in a linear RSM level responses (p<0.05). Serum blood urea nitrogen concentration tended to decrease (linear, p = 0.07; p = 0.08) at 6th wk of growing and 13th wk of finishing periods and digestibility of dry matter tended to decrease by dietary RSM (linear, p = 0.09). Crude protein, crude fat and nitrogen retention, whereas, were not affected by dietary RSM supplementation level. In the economic analysis, feed cost per weight gain was numerically decreased when RSM was provided up to 9%. Consequently, RSM could be supplemented to growing-finishing diets up to 9% ($3.07{\mu}mol/g\;Gls$) without detrimental effects on growth performance of growing-finishing pigs.

• Asian-Australasian Journal of Animal Sciences
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• 제2권2호
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• pp.59-66
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• 1989

Growing and finishing Korean native bulls were used to investigate the effects of different dietary energy levels on performance and energy intake. Experimental observations were made over three weight categories (200 to 250 kg, 250 to 350 kg and 350 to 450 kg). Three diets (2.4, 2.6 and 2.8 Mcal ME/kg DM) were used for each weight category. Crude protein levels of the diets were 12, 11 and 10% for the respective weight groups. Dietary energy level did not significantly affect daily body gain within a weight range but daily body gain during the entire experiment was higher (P<.05) in bulls receiving 2.6 Mcal energy diet than in those fed 2.4 and 2.8 Mcal energy diets. The following equation was developed to predict daily body gain(Y) from energy levels(X) of ration. $Y\;=\;1.3.475X\;-\;2.5949X^{2}\;-\;16.355$ Increasing energy levels significantly (P<.05) decreased daily feed intake. The following equation was developed to predict daily feed intake(Y) from energy levels(X) of ration. $Y\;=\;-30.013X\;+\;5.4401X^{2}\;+\;49.119$ Feed intake per metabolic body size during the entire feeding period ranged from 100.9 to 110.8 g and was lower in bulls fed 2.6 and 2.8 Mcal energy diets than in those fed 2.4 Mcal energy diet. Increasing energy levels significantly (P<.05) improved feed efficiency. The following equation was developed to predict feed efficiency(Y) from energy levels(X) of ration. $Y\;=\;-118.34X\;+\;22.448X^{2}\;+\;162.85$ Daily energy intake during the entire experiment ranged from 18.90 to 19.99 Mcal and there was no significant difference among energy levels. Daily energy intake per metabolic body size during the feeding period ranged from 248.6 to 260.8 kcal and was slightly higher in bulls receiving 2.8 Mcal than in those fed 2.4 and 2.6 Mcal energy diets. Energy required per kg body gain ranged from 17.25 to 19.11 Mcal and was slightly lower in bulls receiving 2.6 Mcal energy diet than in those fed 2.4 and 2.8 Mcal energy diets.

• 한국축산식품학회지
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• 제21권4호
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• pp.307-313
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• 2001

본 연구는 일본 동경지역에서 시판되고 있는 한국산과 각국산 계육의 미생물학적, 물리화학적 품질특성을 비교분석하였다. 시료는 일본 동경 지역 판매점에서 냉동저장(-2$0^{\circ}C$$\pm$1) 상태에서 시판되고 있는 각국산 계육의 가슴육과 다리육을 각각 구입하여 일본 낙농학원대학 식품과학과 연구실에서 실험이 진행되었다. 가슴육은 한국산과 일본산, 중국산이 비교분석되었고, 다리육은 한국산 일본산, 중국산, 미국산, 태국산이 각각 비교분석되었다. 가슴육의 일반성분의 경우 조지방의 함량은 한국산 계육의 경우 가장 낮은 함량을 나타내었고, 조단백질과 조회분(P<0.01)은 중국산 닭고기가 가장 낮은 함량을 나타내었으나, 수분 함량은 가장 높은 수준을 보였으며 P<0.001수준에서 유의적인 차이를 나타내었다. 가슴육의 물리화학적 특성에서는 보수성의 경우 일본산 닭고기가 가장 높게 나타났으나, 지방의 산화정도를 나타내는 TBA값이 한국산과 중국산에 비하여 높게 나타났다. 가슴육의 미생물수준은 각 국산간에 총균수, 대장균군 모두 고도의 유의적인 차이를 나타내었으며(P<0.001), 총균수의 경우 중국산이 가장 높게 나타났으며, 한국산 닭고기 가슴육은 가장 높은 대장균군을 나타내었다. 다리육의 일반성분 경우 수분은 미국산과 태국산이 높게 나타났으며(P<0.001), 조지방 함량은 미국산 닭고기 다리육에서 가장 높게 나타났다(P<0.001). 닭고기 다리육의 명도(L value)와 황색도(b value)는 모두 고도의 유의적인 차이를 나타내었으며(P<0.001), 명도의 경우 태국산과 일본산이 가장 높은 수준을 나타내는 반면 황색도에서는 일본산의 경우 가장 낮은 수준을 나타내었다. 닭고기는 다리육의 미생물수준은 총균수와 대장균군 모두 고도의 유의적인 차이를 나타내었다(O<0.001). 총 균수는 태국산이 $10^{5}$ 이상의 수준으로 가장 높게 나타났고, 그 외 다른 나라들의 경우는 $10^{4}$이상의 수준으로 유사한 수준을 나타내었다. 대장균군의 경우 미국산과 한국산, 중국산이 다소 높은 경향을 보였다.다.