• Investigative Magnetic Resonance Imaging
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• v.24 no.3
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• pp.174-177
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• 2020

Multiple studies have established that mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) exhibits reversible diffusion restriction in the white matter, including the splenium. There have been a few previous reports of the change in fractional anisotropy (FA) of MERS cases. Herein, we report the longitudinal changes in axial and radial diffusivity (AD and RD), and FA in a 15-year-old boy patient with MERS. Our case demonstrated that a MERS lesion had a significant drop of AD in the early period and gradual recovery. On the contrary, RD did not show any significant change.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.1 s.232
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• pp.27-34
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• 2005

We analyze in detail axially symmetric theoretical study for the photothermal pulsed radiometry of a cylindrical model. The theoretical solutions describe the transient infrared radiation from the sample heated by short-duration pulsed heating. In the conventional transmission radiometry technique, the excitation source and the detector are on opposite sides of the sample, otherwise in the new single ended radiometry technique, the excitation source and the detector are on same sides of the sample. The analytical solution described for photothermal radiometry in this study would not need to cut or polish samples to measure the thermal diffusivity. Therefore the radial area and axial thickness of samples are not limited. The effects of excitation pulse duration and the area of heat source are discussed.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1142-1151
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• 2021

Objective: To evaluate microstructural damage in high myopia (HM) patients using 3T diffusion kurtosis imaging (DKI). Materials and Methods: This prospective study included 30 HM patients and 33 age- and sex-matched healthy controls (HCs) with DKI. Kurtosis parameters including kurtosis fractional anisotropy (FA), mean kurtosis (MK), axial kurtosis (AK), and radial kurtosis (RK) as well as diffusion metrics including FA, mean diffusivity, axial diffusivity (AD), and radial diffusivity derived from DKI were obtained. Group differences in these metrics were compared using tract-based spatial statistics. Partial correlation analysis was used to evaluate correlations between microstructural changes and disease duration. Results: Compared to HCs, HM patients showed significantly reduced AK, RK, MK, and FA and significantly increased AD, predominately in the bilateral corticospinal tract, right inferior longitudinal fasciculus, superior longitudinal fasciculus, inferior fronto-occipital fasciculus, and left thalamus (all p < 0.05, threshold-free cluster enhancement corrected). In addition, DKI-derived kurtosis parameters (AK, RK, and MK) had negative correlations (r = -0.448 to -0.376, all p < 0.05) and diffusion parameter (AD) had positive correlations (r = 0.372 to 0.409, all p < 0.05) with disease duration. Conclusion: HM patients showed microstructural alterations in the brain regions responsible for motor conduction and vision-related functions. DKI is useful for detecting white matter abnormalities in HM patients, which might be helpful for exploring and monitoring the pathogenesis of the disease.

• The Korean Journal of Pain
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• v.32 no.4
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• pp.271-279
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• 2019

Background: We utilized diffusion tensor imaging (DTI) to evaluate the cerebral white matter changes that are associated with phantom limb pain in patients with unilateral arm amputation. It was anticipated that this would complement previous research in which we had shown that changes in cerebral blood volume were associated with the cerebral pain network. Methods: Ten patients with phantom limb pain due to unilateral arm amputation and sixteen healthy age-matched controls were enrolled. The intensity of phantom limb pain was measured by the visual analogue scale (VAS) and depressive mood was assessed by the Hamilton depression rating scale. Diffusion tensor-derived parameters, including fractional anisotropy, mean diffusivity, axial diffusivity (AD), and radial diffusivity (RD), were computed from the DTI. Results: Compared with controls, the cases had alterations in the cerebral white matter as a consequence of phantom limb pain, manifesting a higher AD of white matter in both hemispheres symmetrically after adjusting for individual depressive moods. In addition, there were associations between the RD of white matter and VAS scores primarily in the hemispheres related to the missing hand and in the corpus callosum. Conclusions: The phantom limb pain after unilateral arm amputation induced plasticity in the white matter. We conclude that loss of white matter integrity, particularly in the hemisphere connected with the missing hand, is significantly correlated with phantom limb pain.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.9
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• pp.2443-2453
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• 1994

The structure of turbulence of fully developed flow through four concentric annuli with the rough outer wall was investigated experimentally for a Reynolds number range Re=15, 000-93, 000. Turbulence intensities were measured in three(u, v, w) directions, and turbulence shear stresses in annuli of radius=0.13, 0.26, 0.4 and 0.56, respectively. Due to the square roughness element attached periodically along the axial direction, the radial velocity fluctuations show similar distribution regardless of the different .alpha.cases. However, the axial and circumferential velocity fluctuation profiles demonstrate the longitudinal turbulence structures are strongly influenced by the .alpha. values. The turbulent eddy viscosity deduced form mean velocity distributions and the measured Reynolds shear stresses are also presented and discussed.

• Korean Journal of Radiology
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• v.22 no.5
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• pp.759-769
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• 2021

Objective: To evaluate the application of laplacian-regularized mean apparent propagator (MAPL)-MRI to brain glioma-induced corticospinal tract (CST) injury. Materials and Methods: This study included 20 patients with glioma adjacent to the CST pathway who had undergone structural and diffusion MRI. The entire CSTs of the affected and healthy sides were reconstructed, and the peritumoral CSTs were manually segmented. The morphological characteristics of the CST (track number, average length, volume, displacement of the affected CST) were examined and the diffusion parameter values, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), radial diffusivity (RD), mean squared displacement (MSD), q-space inverse variance (QIV), return-to-origin probability (RTOP), return-to-axis probabilities (RTAP), and return-to-plane probabilities (RTPP) along the entire and peritumoral CSTs, were calculated. The entire and peritumoral CST characteristics of the affected and healthy sides as well as those relative CST characteristics of the patients with motor weakness and normal motor function were compared. Results: The track number, volume, MD, RD, MSD, QIV, RTAP, RTOP, and RTPP of the entire and peritumoral CSTs changed significantly for the affected side, whereas the AD and FA changed significantly only in the peritumoral CST (p < 0.05). In patients with motor weakness, the relative MSD of the entire CST, QIV of the entire and peritumoral CSTs, and the AD, MD, RD of the peritumoral CST were significantly higher, whereas the RTPP of the entire and peritumoral CSTs and the RTOP of the peritumoral CST were significantly lower than those in patients with normal motor function (p < 0.05 for all). In contrast, no significant changes were found in the CST morphological characteristics, FA, or RTAP (p > 0.05 for all). Conclusion: MAPL-MRI is an effective approach for evaluating microstructural changes after CST injury. Its sensitivity may improve when using the peritumoral CST features.

• Fire Science and Engineering
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• v.16 no.3
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• pp.1-7
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• 2002

Diffusion and dispersion of injected $CO_2$gas into the $N_2$ gas flow are complex. In the packed column with porous particles the axial dispersion and the extra-particle mass transport as well as the intra-particle mass transport are involved. The pulse spreads by stationary diffusion during the period of arrested flow. Hence, the effect of axial dispersion, and of entrance and exit, as well as that of intraparticle convection should be eliminated during the period. The effective diffusivity was determined experimentally by using the gas chromatography, which is to arrest the gas flow during the period after injecting the pulse. This experiment method hasn't been used often in the field. Effective diffusivities are raised with temperature increasing, and it is quite satisfied com-pared to literature values. In this study, the calculated data of gaseous chemical for extinguish fires could be helpful to appreciate several physical phenomenons. Also, it could be expected that, the calculated data of this study might be very useful for development of excellent gaseous chemical for extinguish fires and improvement of its efficiency.

• Transactions of the Korean Society of Mechanical Engineers
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• v.13 no.2
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• pp.257-264
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• 1989

For the extension of the flash method the heat diffusion equation with heat loss and with an arbitrary heat pulse is mathematically analyzed. In the analysis the heat loss includes the axial and radial directions on the front, rear and peripheral surfaces. The heat pulse is irradiated from the source to the front surface of the sample and the heat receiving area on the front surface is controlled by the apertures of an optical system. From this analysis the thermal diffusivity of the samples can be determined more precisely than before by the data reduction method using various percent time. The data can be obtained by the extended radial flash technique adjusted correctly the heating area on the central part of the front surface with a proper aperture or the conventional axial flash technique heated uniformly all parts of the front surface.

• Biotechnology and Bioprocess Engineering:BBE
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• v.7 no.1
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• pp.16-20
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• 2002

Parameter estimations were made for the reversed-phase adsorption of perillyl alcohol (POH), a potent anti-cancer agent, on octadecylsilyl-silica gel (ODS). The average particle diameter of ODS was about $15\;{\mu}m$, and the particles were packed in the column $(3.9\;\times\;300mm)$. The mobile phase used was a mixture of acetonitrile and water, in which the acetonitrile ranged between 50 and $70\;(v/v\;\%)$. The first absolute moment and the second central moment were determined from the chromatographic elution curves by moment analysis. Experiments were carried out using POH solutions within the linear adsorption range. The fluid-to-particle mass transfer coefficient was estimated using the Wilson-Geankoplis equation. The axial dispersion coefficient and the intra particle diffusivity were determined from the slope and intercept of a plot of H vs $1/u_0$, respectively. The contributions of each mass-transfer step were axial dispersion, fluid-to-particle mass transfer, and intraparticle diffusion.

• International Journal of Air-Conditioning and Refrigeration
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• v.9 no.2
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• pp.77-84
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• 2001

Experimental and computational studies were carried out to investigate the turbulent heat transfer enhancement of the cooling system in nuclear reactor by large scale vortex generation. The large scale vortex motion was generated by rearranging the inclination angels of mixing vanes to the coordinate direction. Axial development of mean and turbulent velocities in the subchannels were measured by the 2-color LDV system. Eddy diffusivity concept based on $\kappa{-}\varepsilon$ model was employed to calculate the turbulent heat and momentum transfers in the subchannel. The turbulences generated by split mixing vanes has small length scales so that they maintain only about $10D_H$ after the spacer grid. On the other hand, the turbulences generated by the large scale vortex motions continue longer and remain up to $25D_H$ after the spacer grid.