• 제목/요약/키워드: Average treatment effect

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성장장애(成長障碍)를 주소(主訴)로 내원(來院)한 환아(患兒) 200례(例)에 대(對)한 임상적(臨床的) 관찰(觀察) (A Clinical Inquiry into 200 Cases of Children Coming to the Clinic Due to the Symptom of Growth Deficiency)

  • 나동규
    • 혜화의학회지
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    • 제7권2호
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    • pp.609-620
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    • 1999
  • Over the period between January 1997 and December 1998, herbal medicine was more than three times administered to the patients coming to Na dong gyu's Oriental Medical Clinic on account of the symptom of growth deficiency. According to radiological opinions about the patients providing cooperation for measuring their height and weight as well as their bone age every three months, it was found that the growth plates were not closed. A research was conducted for 200 children randomly selected of patients in prepuberty (they grew by less than 5cm a year before treatment at a age of 12years for female children and 14years for male children). As a result, the following conclusion was drawn: 1. The randomly selected subjects were made up of 116 male and 84 female children in terms of gender. The age direstribution was most 10 to 12 years in 86 children(34.00%), followed by 8-10 years(27.50%) and 12 to 14 years(19.50%). 2. Considering the distribution of sick children's parental height, the fathers of 141 children(70.50%) measured less than 170cm high, the subaverage height, while the mothers of 172 children(86%) measured less than 160cm high, the subaverage height. It was shown that sick childen's height was genetically influenced by their parents. 3. Children patients's weight at a time of birth was most 3.1-3.5kg for 85 children(44%) and less than 2.5kg which came under the range of growth dificiency for 19 children(9.5%). 4. The highest proportian of the children patients with growth dificiency(56.33%) had the symptom of digestive disorders, of which 77 children patients(18.78%) had anorexia, 16.59% of children patients had the high level of respiratory disorders. Both the digestive disorder and the respiratory disorder put together, they had the high rate of 72.92%. Therefore, this indicates that both the digestive disorder and the respiratory disorder have a great effect on children's growth dificiency. 10.74% of chilren patients were shown to have allergic disorders, which indicates that they also exert an effect on growth deficiency. Specifically, 7.07% of the children patients had the high level of obesity, which shows that an excessive uptake of nutrition may rather induce children to have growth dificiency though an appropriate amount of nutritional uptake is necessary. 5. Comparing their bone age and their chronological age, 58 children patients(29.00%) showed that they were the same at the highest percent. 79 children patients(39.50%) showed that thier bone age was lower than their chronological age. And 63 children patients(31.50%) showed that their bone age was higher than their chronological age. 6. As regards the prescription administered to children patients for treating their growth dificiency, Growth tang A related to the kidney, the congenital factor, of the causes for growth dificiency in traditional Oriental Medicine was administered to 108 children patients(54%), whereas the Growth tang B related to the spleen, the acquired factor, was administered to 92 children patients(46%). 7. 116 male children patients with growth dificiency had the average value of growth for one year before treatment, 4.39cm, while 84 female children patients had the average value of growth for one year before treatment, 4.24cm. A total of 200 children had the average value of growth for one year before treatment, 4.33cm. The annual average value of growth in growth curve surveyed by the Korea Pediatrics Society was 5.79cm. Compared to this value, the one year average value of growth for 108 male and female children patients taking Growth tang A was shown be 8.44cm, which indicates a greater growth by 4.12cm(95.37%) in comparison with the average value of growth before treatment, 4.32cm, and a greater growth by 2.65cm(45.77%) compared to 5.79cm, the average value of growth in growth curve surveyed by the Korea Pediatrics Society. Also, the average value of growth before treatment for 92 male and female children patients taking Growth tang B was shown to be 8.47cm, which indicates a greater increase by 4.15cm(96.06%) compared to 4.32cm, the average value of growth before treatment and a greater increase by 2.67cm(46.29%) in comparison with 5.79cm, the average value of growth in growth curve surveyed by the Korea Pediatrics Society. Considering the average value of growth for male and female children patients taking Growth tang A and B, it was shown to be 8.46cm, which indicates a greater increase by 4.14cm(95.81%) compared to 4.32cm, the average value of growth before treatment, and a greater increase by 2.67cm(46.11%) compared to 5.79cm, the average value of growth in growth curve surveyed by the Korea Pediatrics Society.

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저농도 도시하수 처리를 위한 활성슬러지공정에서 HRT 및 SRT가 처리효율에 미치는 영향 (The Effect of HRT and SRT on Treatment Efficiency of Activated Sludge Process for Low Concentration Municipal Sewage)

  • 황규대;김민호;고새봄
    • 상하수도학회지
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    • 제11권1호
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    • pp.64-73
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    • 1997
  • Most of the municipal wastewater treatment plants operated in Korea are designed for high concentrations municipal sewage. However, activated sludge process employed by municipal wastewater treatment plant is operated at low organic loading. The objective of this study was to determine optimum operating condition of activated sludge process for treatment of low concentration municipal sewage. Three bench scale activated sludge reactors were operated to investigate the effect of HRT and SRT on the COD and TSS removal efficiency. The average concentration of TSS, SCOD, SBOD and TKN in influent were 118mg/l, 61mg/l, 21mg/l, and 12mg/l, respectively. The activated sludge reactors operated with various HRT and SRT showed about 89-93% TSS removal efficiency. HRT and SRT does not affect the TSS removal efficiency of actvatied sludge process significantly. However, HRT affected the SCOD removal efficiency slightly. As the HRT decreases from 13hours to 3hours, the SCOD removal efficiency decreases from 67% to 56%. The average effluent TCOD concentration of the reactor operated with 3hours of HRT was approximatly 40-45mg/l. Kinetic coefficient yield (Yt) and decay coefficients(Kd) were 0.594-0.954 mgMLVSS/mgCOD and $0.0197-0.0317day^{-1}$, respectively. Low concentration municipal sewage can be treated with 3 hours of HRT without effluent quality deterioration and SRT does not affect the substrate removal efficiency at this operation condition.

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핵연료 피복관용 지르칼로이-4의 미세조직과 기계적 특성에 미치는 $\beta$-열처리의 영향 (The Effect of $\beta$-Heat Treatment on the Microstructure and Mechanical Characteristics of Zircaloy-4 for Nuclear Fuel Cladding)

  • 고진현;오영근;김광수
    • 한국재료학회지
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    • 제9권6호
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    • pp.589-594
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    • 1999
  • The effect of $\beta$-heat treatment on th microstructure, mechanical properties and texture in the nuclear fuel cladding of Zircaloy-4 tubes was chosen at 1000, 1100 and 120$0^{\circ}C$, and the tubes were heat-treated by a high frequency vacuum induction furnace. Morphology of the second phase particles and $\alpha$-grain of as-received tubes were markedly changed by heat treatment. The average sizes of second phase particles of as-received and $\beta$-heat treated tubes were 0.1$\mu\textrm{m}$ and 0.076$\mu\textrm{m}$, respectively. However, the average sizes of second phase particles were not much changed in the $\beta$-heated temperatures. With increasing heat treatment temperatures, the 0.2% yield strength and the hoop strength were decreased because of changes in preferred orientation as will as $\alpha$-plate width. Heat treated Zircaloy-4 tubes exhibited texture changes but the preferred orientation of grains still remained.

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REACTION TIME, SEMEN OUTPUT AND SEMEN QUALITY OF BUFFALO BULLS AFTER PRE-COLLECTION INJECTION OF PROSTAGLANDIN F2 ALPHA (PGF2 ALPHA)

  • Capitan, S.S.;Antiporda, G.S.;Momongan, V.G.
    • Asian-Australasian Journal of Animal Sciences
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    • 제3권4호
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    • pp.343-346
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    • 1990
  • A study was conducted to determine the effect of prostaglandin $F_2$ alpha ($PGF_2$ alpha) on the reaction time and seminal characteristics of buffalo bulls. Semen was collected from three Murrah bulls in three periods: pre-treatment, treatment and post-treatment. During the treatment period each bull was administered 2 ml $PGF_2$ alpha (Synchrocept, Fenprostalene) im, 1 hour prior to semen collection. In the post-treatment, semen was collected 7 days after the last injection of $PGF_2$. Semen samples were evaluated immediately after collection. Pre-collection injection of $PGF_2$ alpha has no significant effect on reaction time, semen volume, percentage motility, sperm concentration and total number of sperms per ejaculate. Fluctuations in semen color and consistency were observed. There is a significant (p<0.05) increase in the mean percentage of normal spermatozoa during the treatment and post treatment periods. Likewise, administration of PG results into a significant (p<0.05) rise on the average percentage of live sperms but this effect was not manifested in the post-treatment period. Improvement in mass activity was observed during the treatment and post-treatment periods.

Comparative Study on the Clinical Trial of Acupotomy Treatment for Lumbar Disk Herniation

  • Beom Seok Kim;Ju Hyun Jeon;Tae Yong Park;Hong Kyoung Kim;Young Il Kim
    • Journal of Acupuncture Research
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    • 제40권3호
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    • pp.252-264
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    • 2023
  • Background: The primary aim of this study is to statistically analyze and compare the difference in treatment outcomes based on the frequency and duration of acupotomy treatment for lumbar disk herniation. Methods: The evaluation of efficacy and safety involved using visual analog scale (VAS), numeric rating scale (NRS), Roland Morris disability questionnaire (RMDQ), EuroQol 5-dimention (EQ-5D), and similar parameters. This was achieved through the establishment of a comparable cohort using propensity score matching. Group A comprised 46 patients who underwent 4 sessions of acupotomy treatment for 2 weeks, while Group B consisted of 15 patients who received 6 acupotomy sessions for 3 weeks. Results: For Group A, the average amount of change in VAS values at weeks 4 and 6 was significantly decreased. However, the average amount of change in RMDQ values was not significant. Notably, the average amount of change of EQ-5D values at week 6 increased significantly. As for Group B, the average amount of change of NRS values in weeks 2 and 3 was significantly decreased. Conversely, the average amount of change in RMDQ and EQ-5D values was not significant. In comparing the 2 groups at the final follow-up, the average amount of change in all evaluation values was not significant. Further, no significant interaction effect was observed in the changes over time in all evaluation values between the 2 groups. Conclusion: This study establishes that there was no statistically significant difference in pain reduction, functional impairment, and quality of life improvement between 2 group.

Outcomes of comprehensive fixed appliance orthodontic treatment: A systematic review with meta-analysis and methodological overview

  • Papageorgiou, Spyridon N.;Hochli, Damian;Eliades, Theodore
    • 대한치과교정학회지
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    • 제47권6호
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    • pp.401-413
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    • 2017
  • Objective: The aim of this systematic review was to assess the occlusal outcome and duration of fixed orthodontic therapy from clinical trials in humans with the Objective Grading System (OGS) proposed by the American Board of Orthodontics. Methods: Nine databases were searched up to October 2016 for prospective/retrospective clinical trials assessing the outcomes of orthodontic therapy with fixed appliances. After duplicate study selection, data extraction, and risk of bias assessment according to the Cochrane guidelines, random-effects meta-analyses of the mean OGS score and treatment duration were performed and 95% confidence intervals (CIs) were calculated. Results: A total of 34 relevant clinical trials including 6,207 patients (40% male, 60% female; average age, 18.4 years) were identified. The average OGS score after treatment was 27.9 points (95% CI, 25.3-30.6 points), while the average treatment duration was 24.9 months (95% CI, 24.6-25.1 months). There was no significant association between occlusal outcome and treatment duration, while considerable heterogeneity was identified. In addition, orthodontic treatment involving extraction of four premolars appeared to have an important effect on both outcomes and duration of treatment. Finally, only 10 (39%) of the identified studies matched compared groups by initial malocclusion severity, although meta-epidemiological evidence suggested that matching may have significantly influenced their results. Conclusions: The findings from this systematic review suggest that the occlusal outcomes of fixed appliance treatment vary considerably, with no significant association between treatment outcomes and duration. Prospective matched clinical studies that use the OGS tool are needed to compare the effectiveness of orthodontic appliances.

벨 마비 재발 환자에 대한 임상적 고찰: 후향적 관찰연구 (Clinical study on recurrent Bell's palsy: A retrospective observational study)

  • 김민주;최현규;차현지;이영록;장현진;김소정;전주현;김영일
    • 대한한의학회지
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    • 제43권2호
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    • pp.8-26
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    • 2022
  • Objectives: This study is designed to statistically analyze characteristics, treatment effect and prognosis of patients who were treated for the recurrent Bell's palsy Methods: This study retrospectively analyzed the medical records and telephone questionnaire of 82 patients treated with the recurrent Bell's palsy at the OO Korean Medicine hospital from August 01, 2018 to July 31, 2021. Results: The lower the EQ-VAS® and HB scale before and after treatment, the higher the satisfaction with the treatment. The average of the number of days and duration of outpatient treatment for male was longer than that for female. The average number of days and duration of outpatient treatment in the group that received combined treatment was longer than that of patients who received Korean Medicine only. The higher the satisfaction of treatment, the higher the willingness to receive treatment in the event of recurrent facial palsy. HB scale after treatment was the lowest in their 40s, and the average value of HB scale after treatment tended to increase as age increased except for those in their 40s. Conclusion: This study showed that the lower the HB scale after treatment, the lower the EQ-VAS®, the higher the treatment satisfaction, and the higher the probability receiving treatment if the facial paralysis recurs. Those in their 10s to 40s showed excellent results after treatment. Comparatively, those in their 50s and above showed a little effect after treatment. Gender, affected side, history of facial palsy, season of onset, age, hypertension and diabetes had no statistically significance with recurrent Bell's palsy prognosis.

한의학적 치료로 호전된 안면비대칭 5례 (The Effect of Korean Medical Treatments for Facial asymmetry Patients : Five Cases Report)

  • 신정민;안진향;이진혁
    • 대한한의학회지
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    • 제40권3호
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    • pp.198-223
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    • 2019
  • Objectives: The purpose of this study was to investigate the effect of Korean medicine treatment on facial asymmetric treatment in 5 cases of facial asymmetry correction by non - surgical treatment such as acupucture, chuna treatment, FCST (Functional cerebrospinal technique) and cranial osteopathy. Methods: We analyzed the initial charts of 5 patients who had undergone facial asymmetry in a Korean medicine clinic and measured the position and distance using the photograph, lateral cephalograms, and whole body radiograms. The results were as follows. Results: To quantify both soft and hard tissues to confirm the results of Korean medicine treatment of facial asymmetry, soft tissues quantitatively measure the displacement of the face, the slope of the left and right eyes, and the slope of the lip in order to grasp the positional displacement of the mandible. As a result, on the average, the correction effect as measured by the angle difference between A and C is $1.8{\pm}0.57$, the correction effect as measured by the angle difference between B and C is $1.4{\pm}0.89$, and the angle difference between D and the horizontal plane is $1.9{\pm}0.89$, and the angle difference between E and the horizontal plane is $1.9{\pm}0.89$. The result of reduced angle difference between A and C means that the head position shifted from the center of the body to the unilateral side was shifted to the center. The decrease in the angle difference between B and C means the restoration of the maxillary distortion relative to the mandible. In hard tissues, numerical values were measured based on the skull standard. The average distortion of the skull was $1.9{\pm}0.67$, and the distortion of the lower eye was $1.4{\pm}0.41$. Conclusion: General studies on facial asymmetric treatment are limited to treatments such as surgery and orthodontics. However, this study confirmed the possibility that facial asymmetry could be corrected by Korean medical treatment consisting of reversible non-surgical treatment rather than irreversible treatment such as surgery or orthodontic treatment. In particular, Korean medicine treatment is effective for muscular asymmetry, soft asymmetry, functional asymmetry, etc. The facial asymmetric treatment of Korean medicine is not limited to the face-centered correction, but the asymmetry of the whole body may be corrected as well.

한방병원 중증치료실 입원 중 항생제 연관성 설사를 진단받은 환자에 대한 임상적 고찰 (Clinical Study of Antibiotic-associated Diarrhea Treatment in Intensive Care Unit Patients at an Oriental Hospital)

  • 양가은;김슬지;박영주;이미정;이지숙;류재환
    • 대한한방내과학회지
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    • 제31권2호
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    • pp.298-307
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    • 2010
  • Objectives : This study was designed to investigate the effectiveness of adjunctive herbal therapy combined with conventional therapy on antibiotic-associated diarrhea (AAD) treatment. Methods : The medical records of 25 patients admitted to the Intensive Care Unit at Kyunghee Oriental Medical Center between January 1, 2009 and January 30, 2010 were reviewed. The charts were analyzed for the general characteristics, site of infection, predominant bacteria, antibiotic treatment, herbal medicine treatment, effect on liver and kidney functions, and the effect of therapy on diarrheal duration. Results : 48% of the 25 patients were male while 52% were female. The average age was 67.2 years old. The most commonly used antibiotic was fluoroquinolone (40.0%) and the most commonly used herbal medicine was Samchulkunbi-tang (24.0%). The average diarrheal duration was 8.9 days. No significant change in hepatic and renal function was discovered before and after treatment with herbal medicine. Conclusions : The results suggest that herbal therapy would be a safe and effective treatment for AAD. Further study investigating the usage of herbal medicine in AAD treatment is anticipated.

수기요법(手氣療法)에 따른 체열변화(體熱變化)의 비교(比較) 연구(硏究) (A Study on Thermographic Change of DITI by Sugi Therapy.)

  • 최지영;허진;정명수;이기남
    • 대한의료기공학회지
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    • 제11권1호
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    • pp.59-79
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    • 2009
  • Objective: I carried out this study for research on thermographic change of DITI by Sugi Therapy. Methods: This study was conducted on 22 normal cases (M : F =4:18) with no past history to observe the effect of Sugi Therapy. 22 cases were divided into 2 groups. One group is a control group treated by only Acupuncture Therapy. The other group is a treatment group treated by Acupuncture Therapy and Sugi Therapy. I measured temperature of abdomen and palm by DITI (Digital Infrared Thermographic Imaging) before and after treatment Result: 1. Overall the temperature difference of the treatment group was bigger than that of the control group. 2. On the palm, the average value of the treatment group was -0.56±0.70, which is lower 10 times than -0.06±0.91 of the control group. 3. On Chung-wan(CV12), the average value of the treatment group was 1.20±0.49, which is 2.15 times higher than 0.56±0.44 of the control group. 4. On Kwanwon(CV4), the average value of the treatment group was 0.77±0.73, which is 1.38 times higher than 0.55±0.39 of the control group. 5. To compare the temperature difference on the palm, Chung-wan(CV12) and Kwanwon(CV4) before and after treatment, the order is like this :Chung-wan(CV12) > Kwanwon(CV4) > palm of all treatment group and control group. Conclusion: I came to a conclusion that Sugi Theraphy is likely to work better with Acupuncture Therapy better than only Acupuncture Therapy, especially on Chung-wan(CV12).