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Use of succimer as an alternative antidote in copper sulfate poisoning: A case report (황산구리 중독에서 대안 해독제로의 succimer 사용 1례)

  • Han, Sang Kyoon;Park, Sung Wook;Cho, Young Mo;Wang, Il Jae;Bae, Byung Kwan;Yeom, Seok Ran;Park, Soon Chang
    • Journal of The Korean Society of Clinical Toxicology
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    • v.19 no.1
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    • pp.59-63
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    • 2021
  • Copper sulfate is widely used as a fungicide and pesticide. Acute copper sulfate poisoning is rare but potentially lethal in severe cases. Copper sulfate can lead to cellular damage of red blood cells, hepatocytes, and myocytes. Toxic effects include intravascular hemolysis, acute tubular necrosis and, rhabdomyolysis. A 76-year-old man presented with vomiting and epigastric pain. He had ingested a copper-containing fungicide (about 13.5 g of copper sulfate) while attempting suicide 2 hours prior to presentation. From day 3 at the hospital, laboratory findings suggesting intravascular hemolysis were noted with increased serum creatinine level. He was treated with a chelating agent, dimercaptosuccinic acid (succimer). His anemia and acute kidney injury gradually resolved with a 19-day regimen of succimer. Our case suggests that succimer can be used for copper sulfate poisoning when other chelating agents are not available.

An Automation Instructor System using Finite State Machine within Web services

  • Aldriwish, Khalid
    • International Journal of Computer Science & Network Security
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    • v.21 no.7
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    • pp.233-240
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    • 2021
  • The majority of the Web's success can be related to its productivity and flexibility. Web Services (WSs) have the means to create new patterns for the delivery of software capabilities. The WS easily provides the use of existing components available via the Internet. WSs are a new trend that shares ubiquitous systems with others, so the popularity of the Web is increased day by day with their associated systems. This paper will explore and adopt the possibility of developing a technique that will automate instructors' scheduling of timetables within a Web services environment. This technique has an advantage that facilitates users to reduce the time cost and effort by reducing errors and costs for institutes. Providing dependable tables to avoid mistakes related to instituting schedules is ensured by an automated repetitive manual procedure. Automated systems are increasingly developed based on organizations and their customers. Still, the setting's difficulty of automation systems increases to rise as the system architecture and applications must accomplish various requirements and specifications of ever-demanding project scenarios. The automation system is composed of an operating system, platforms, devices, machines, control system, and information technology. This architecture provides more productivity and optimized services. The main purpose of this paper is to apply an automation system to enhance both quality and productivity. This paper also covers an agile method of proving an automation system by Finite State Machine (FSM) and Attributed Graph Grammar (AGG) tool.

Nuss Procedure for Surgical Stabilization of Anterior Flail Chest with Mechanical Ventilation Weaning Failure: A Case Report

  • Kim, Donghee;Yoon, Seung Keun;Lee, Geun Dong;Kim, Dong Kwan
    • Journal of Chest Surgery
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    • v.55 no.2
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    • pp.183-187
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    • 2022
  • Flail chest is a critical medical condition in which multiple segmentally fractured adjacent ribs cause paradoxical movement of the thoracic cage in patients with severe blunt trauma injury. Surgical stabilization is considered essential in patients who require mechanical ventilation. However, there is no consensus on which surgical procedure to choose among the various available techniques or when to perform surgery. We report the case of a patient with traumatic anterior flail chest due to bilateral multiple fractures of the ribs requiring surgical stabilization in whom weaning from mechanical ventilation had failed. The Nuss procedure using double bars with the bridge technique was performed for chest wall stabilization. The patient was weaned from mechanical ventilation on postoperative day 44 and she underwent bar removal on postoperative day 71. After extensive rehabilitation for multiple trauma, she was discharged successfully. The patient currently shows no recurrence of chest wall depression in outpatient follow-up.

A Study on the Effect of Customized Education for Small and Medium-sized Businesses Handling Hazardous Chemicals (유해화학물질 취급 중소사업장을 대상으로 한 맞춤형 교육 효과에 관한 연구)

  • Lee, Hyo-Eun;Kim, Min-Gyu;Lee, Bong-Woo
    • Journal of the Korean Society of Industry Convergence
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    • v.25 no.6_2
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    • pp.979-986
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    • 2022
  • Chemical accidents are increasing day by day as the industry develops. To prevent such chemical accidents, Korea enacted the Chemicals Control Act. Through these laws, systematic management of chemical substances began. There are various positions in the companies. hazardous chemical supervisors, equipment and technical human, operators and employees. Chemicals-related education for each position should be provided. As a result of the survey, hazardous chemical supervisors and equipment and technical human liked the overall content of the Chemicals Control Act and the education subject on safety management standards for facilities. Conversely, the operators liked the course on how to wear personal protective equipment. The employees preferred subjects such as classification of chemical substances and prevention of chemical accidents. Currently, various modular textbooks are widely available. Rather than general education, it is necessary to select and provide customized subjects that are preferred and interested according to the position. Then it will be more effective in understanding harzardous chemical substances and in preventing chemical accidents.

Accuracy Analysis of Predicted CODE GIM in the Korean Peninsula

  • Ei-Ju Sim;Kwan-Dong Park;Jae-Young Park;Bong-Gyu Park
    • Journal of Positioning, Navigation, and Timing
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    • v.12 no.4
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    • pp.423-430
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    • 2023
  • One recent notable method for real-time elimination of ionospheric errors in geodetic applications is the Predicted Global Ionosphere Map (PGIM). This study analyzes the level of accuracy achievable when applying the PGIM provided by the Center for Orbit Determination of Europe (CODE) to the Korean Peninsula region. First, an examination of the types and lead times of PGIMs provided by the International GNSS Service (IGS) Analysis Center revealed that CODE's two-day prediction model, C2PG, is available approximately eight hours before midnight. This suggests higher real-time usability compared to the one-day prediction model, C1PG. When evaluating the accuracy of PGIM by assuming the final output of the Global Ionosphere Map (GIM) as a reference, it was found that on days with low solar activity, the error is within ~2 TECU, and on days with high solar activity, the error reaches ~3 TECU. A comparison of the errors introduced when using PGIM and three solar activity indices-Kp index, F10.7, and sunspot number-revealed that F10.7 exhibits a relatively high correlation coefficient compared to Kp-index and sunspot number, confirming the effectiveness of the prediction model.

Efficacy of Chemical Insecticide to Control Alfalfa Weevil Larvae in Field of Alfalfa

  • Seung Min Jeong;Ki Won Lee;Hyung Soo Park
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.44 no.3
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    • pp.185-189
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    • 2024
  • The alfalfa weevil (Hypera postica) is an important pest that causes significant damages to alfalfa crops, reducing yield and quality, but there's a solution. This research had two main goals to evaluate the efficacy of insecticides available in Korea for alfalfa weevil control and to provide data for pest management studies. The experiment, conducted from 2023 to 2024 at the National Institute of Animal Science in Cheonan, Republic of Korea, included four treatment plots: control (CON), early-occurrence (EAR), mid-occurrence (MID), and late-occurrence (LAT). It also included two frequency plots with primary and secondary insecticide using 50% fenitrothion emulsion, which made it truly comprehensive study. The primary insecticide was applied at the first observation of the alfalfa weevil larvae, with subsequent secondary applications at specified intervals. The results showed that two-times insecticide applications significantly reduced larvae populations and increased yield and nutrient content compared to a single application. Specifically, control rates ranged from 94 to 94.7% on the third day after treatment and from 72.2 to 93.4% on the seventh day. Plots with two applications had higher yields and crude protein content. The study concluded that the timing and frequency of insecticide applications are critical to maximizing alfalfa yield and quality, emphasizing the importance of optimized application strategies for effective pest control.

Analysis of Drug Use Reviews in Pediatirc Inpatients (소아입원환자에서의 약물사용 평가)

  • Shin, Eun Jeong;Ha, Hun Joo;Shin, Wan Gyoon;Park, Kwang Jun
    • Korean Journal of Clinical Pharmacy
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    • v.15 no.1
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    • pp.27-33
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    • 2005
  • This study was intended to contribute towards the development of proper drug use system for pediatric patients by investigationg problems related to their medication and identifying drugs that need to be developed into low dosage tab-lets or syrups for pediatric use based on our analysis on the prescriptions for pediatric inpatients from 22 hospitals in South Korea on a day of Feb. 2003. The usage rates in the proportion of less than 0.5 and 1 per unit of oral solid formulation were $29.9{\%}$ and $54.3{\%}$ in hospitals with 1000 beds or more, 36.5 and $60.6{\%}$ in hospitals with 500 to less than 1000 beds, $60.8{\%}$ and $81.6{\%}$ in hospitals with less than 500 beds. Of the 63 oral solid formulation products that were used two or more times in the proportion oi less than 0.5 units, 34 products ($54.0{\%}$) were used as such despite the fact that syrups and lower dosage tablets or capsules were available in the market, and 24 products ($38.1{\%}$) so even when syrup formulations were available. Therefore, it would be desirable that pharmacist communities in charge of dispensing identify the most frequently crushed drugs or those that require special attention in choosing dispensing powders or solutions and develop dispensing guidelines that can be adopted by pharmacists in practice. Moreover government-led policies are needed to encourage development and manufacture of the formulations for pediatrics and to correct unsound prescription and dispensing practices such as using crushed forms of certain oral solid formulations although alternative formulations are available in the market.

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Effect of γ-aminobutyric acid producing bacteria on in vitro rumen fermentation, growth performance, and meat quality of Hanwoo steers

  • Mamuad, Lovelia L.;Kim, Seon Ho;Ku, Min Jung;Lee, Sang Suk
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.7
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    • pp.1087-1095
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    • 2020
  • Objective: The present study aimed to evaluate the effects of γ-aminobutyric acid (GABA)-producing bacteria (GPB) on in vitro rumen fermentation and on the growth performance and meat quality of Hanwoo steers. Methods: The effects of GPB (Lactobacillus brevis YM 3-30)-produced and commercially available GABA were investigated using in vitro rumen fermentation. Using soybean meal as a substrate, either GPB-produced or commercially available GABA were added to the in vitro rumen fermentation bottles, as follows: control, no additive; T1, 2 g/L GPB; T2, 5 g/L GPB; T3, 2 g/L autoclaved GPB; T4, 5 g/L autoclaved GPB; T5, 2 g/L GABA; and T6, 5 g/L GABA. In addition, 27 Hanwoo steers (602.06±10.13 kg) were subjected to a 129-day feeding trial, during which they were fed daily with a commercially available total mixed ration that was supplemented with different amounts of GPB-produced GABA (control, no additive; T1, 2 g/L GPB; T2, 5 g/L GPB). The degree of marbling was assessed using the nine-point beef marbling standard while endotoxin was analyzed using a Chromo-Limulus amebocyte lysate test. Results: In regard to in vitro rumen fermentation, the addition of GPB-produced GABA failed to significantly affect pH or total gas production but did increase the ammonia nitrogen (NH3-N) concentration (p<0.05) and reduce total biogenic amines (p<0.05). Animals fed the GPB-produced GABA diet exhibited significantly lower levels of blood endotoxins than control animals and yielded comparable average daily gain, feed conversion ratio, and beef marbling scores. Conclusion: The addition of GPB improved in vitro fermentation by reducing biogenic amine production and by increasing both antioxidant activity and NH3-N production. Moreover, it also reduced the blood endotoxin levels of Hanwoo steers.

College Students' Learning Satisfaction and Academic Achievement of Learning Nursing English Based on Smart Education (스마트 교육에 기반 한 전문대 학생들의 간호영어 학습에 대한 학습 만족도와 학업 성과)

  • Kim, Hun-Hee;Jung, Dae-Bum
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.621-630
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    • 2015
  • The purpose of study is to comprehend learning satisfaction and academic achievement about the mobile program of nursing English learning constructed as a solution of supporting smart education in J college. The study was conducted from March to December in 2014. The subjects of study are 342 freshmen (39 males, 303 females) of nursing department. Learning satisfaction was analyzed through questionnaires, and academic achievement was investigated through test produced by 3 professors who majored in nursing. Resources analysis was implemented by SPSS 21.0. The study leads to 3 results from the macroscopic perspective. First, there is a difference of satisfaction with whole program between all factors such as mainly used devices, available times, available days, average hours of use per day, available places. Also, items under program satisfaction (subject or content, availability, academic ability) has a difference. Lastly, change of achievement scores by each time was significant.

Determination of calcium and phosphorus utilization in various hatchery by-products for broiler chickens

  • Choi, Hyeon Seok;Park, Geun Hyeon;Kim, Jong Hyuk;Ji, Sang Yun;Kil, Dong Yong
    • Korean Journal of Agricultural Science
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    • v.46 no.2
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    • pp.361-368
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    • 2019
  • The objective of the current study was to determine calcium (Ca) and phosphorus (P) utilization in 4 different hatchery by-products (HBPs) for broiler chickens. The four different HBPs included infertile eggs (IFE), unhatched eggs (UHE), low grade and dead chicks (LDC), and a mixture (MIX) of 55% IFE, 10% UHE, and 10% LDC with 25% hatched eggshells. A total of sixty four 50-day-old Ross 308 broiler chickens were randomly allotted to 1 of 4 dietary treatments with 8 replicates per treatment. Two birds were placed together in one metabolic cage. Additional 16 birds were used to measure the endogenous losses of Ca and P. A forcefeeding procedure (i.e., crop intubation) was used to measure the apparent and true total tract retention (ATTR and TTTR, respectively) of Ca and P in the 4 HBPs. The results showed that the TTTR of Ca in the UHE was less (p < 0.05) than that in the IFE, LDC, and MIX. The amounts of available Ca in the MIX were greater (p < 0.05) than those in the IFE and UHE, which were greater (p < 0.05) than those in the LDC. The TTTR of P was not different among the 4 HBPs. However, the amounts of available P in the LDC were greater (p < 0.05) than those in the IFE and UHE, which were greater (p < 0.05) than those in the MIX. In conclusion, HBPs contain high amounts of available Ca and P because of high concentrations of total Ca and P with a high utilization rate. Therefore, the use of HBPs in broiler diets can reduce costs on Ca and P supplements.