• Title/Summary/Keyword: Autologous

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Trends and Innovations in Autologous Breast Reconstruction

  • Nicole E. Speck;Vendela Grufman;Jian Farhadi
    • Archives of Plastic Surgery
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    • v.50 no.3
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    • pp.240-247
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    • 2023
  • More than 40 years have passed since the description of the first "free abdominoplasty flap" for breast reconstruction by Holmström. In the meantime, surgical advances and technological innovations have resulted in the widespread adoption of autologous breast reconstruction to recreate the female breast after mastectomy. While concepts and techniques are continuing to evolve, maintaining an overview is challenging. This article provides a review of current trends and recent innovations in autologous breast reconstruction.

Mosaicplasty for the Treatment of the Chondral Defect of the Knee (슬관절의 연골결손에 대한 자가 골연골 이식술)

  • Choi, Nam-Hong
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.4 no.1
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    • pp.12-17
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    • 2005
  • Several methods to resurface the lost cartilage of the knee have been used, multiple drilling, microfracture, abrasion arthroplasty Resurfaced cartilages resulting from above techniques are mostly fibrocartilage. Autologous osteochondral graft transfer and autologous chondrocyte transfer are known to resurface the lost cartilage with mostly hyaline cartilage. This article reviews basic researches, indications, operative technique, and clinical results of autologous osteochondral graft transfer.

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Mosaicplasty for The Treatment of the Chondral Defect of The Knee (슬관절의 연골결손에 대한 자가 골연골 이식술)

  • Choi, Nam-Hong
    • Journal of the Korean Arthroscopy Society
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    • v.12 no.3
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    • pp.147-153
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    • 2008
  • Several methods to resurface the lost cartilage of the knee have been used; multiple drilling, microfracture, abrasion arthroplasty. Resurfaced cartilages resulting from above techniques are mostly fibrocartilage. Autologous osteochondral graft transfer and autologous chondrocyte transfer are known to resurface the lost cartilage with mostly hyaline cartilage. This article reviews basic researches, indications, operative technique, and clinical results of autologous osteochondral graft transfer.

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Effects of Autotransfusion using Cell Saver in Cardiac Surgery (개심술시 자가 수혈체계[Cell Saver]의 이용 효과)

  • 안욱수
    • Journal of Chest Surgery
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    • v.25 no.11
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    • pp.1312-1317
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    • 1992
  • Autologous blood transfusion is a common method of reducing the need for homologous blood transfusion during cardiac operations. Between June 1991 and May 1992, 12 cases [Group I] were experienced autologous blood transfusion using Cell Saver undergoing double valve replacement or redo-valve replacement. Control group [N=12, Group II] was selected to above similar operation during same period. The Cell Saver system [Haemonetics Corp.] was employed for autologous blood transfusion. The blood shed in the operative field before and after cardiopulmonary bypass and remained cardiotomy reservior was aspirated by means of a locally heparinized collecting system. After centrifused salvaged blood, the resulting red cell concentrate reinfused subsequently. The patient receiving autologous blood transfusion required significantly less homologous blood transfusion than their control group. [Group I; 3519 $\pm$ 869, Group II; 4622 $\pm$ 856, Respectively; P=0.005] There were no clinical infections in the autotransfusion group. And there was no apparent intergroup difference of the clinical findings, hematologio datas and coagulation parameters. We conclude the autotransfusion using Cell Saver is effective for reducing of the hom-ologlous blood transfusion in cardiac surgery.

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Autologous Lamellar Keratoplasty for the Treatment of Feline Acute Bullous Keratopathy: A Case Report

  • Manbok Jeong
    • Journal of Veterinary Clinics
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    • v.40 no.4
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    • pp.303-307
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    • 2023
  • A 4-year-old female Munchkin cat presented with a 2-day history of a large mass in the left eye. On the first presentation, slit lamp biomicroscopy revealed a large corneal bulla occupying around 40% of the corneal surface along the visual axis. Based on the results, a diagnosis of feline acute bullous keratopathy was made. Due to the location of the extensive corneal bulla, autologous lamellar keratoplasty was performed based on prior studies, to both minimize postoperative complications that may affect axial vision and address any cosmetic concerns the owner had. The autologous lamellar keratoplasty successfully resolved the corneal bulla with no signs of corneal opacities postoperatively. Therefore, autologous lamellar keratoplasty may be a useful surgical treatment for feline acute bullous keratopathy from both the tectonic and optical points of view.

The Result of Autologous Osteochondral Grafting for the Osteochondral Lesion of the Talus (거골의 골연골 병변에 대한 자가 골연골 이식술의 결과)

  • Ahn, Young-Joon;Hahn, Sung-Ho;Yang, Bo-Kyu;Yi, Seung-Rim;Yoo, Jae-Ho;Chung, Shun-Wook;Bin, Sung-Woo;Zoo, Min-Hong;Kim, Seong-Wan
    • Journal of Korean Foot and Ankle Society
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    • v.10 no.1
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    • pp.48-55
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    • 2006
  • Purpose: The purpose of this study is to assess the results of the autologous osteochondral grafting for the osteochondral lesion of the talus. Materials and Methods: This study included 21 patient who had been treated with the open autologous osteochondral grafting between December, 1999 and December 2003. We treated the patients with autologous osteochondral grafting method who had the lesion of stage II or medial lesion of stage III without improvement for at least 6 months, the medial lesion of stage IV, the lateral lesion of stage III, IV by Berndt and Harty's classification or who had not improved with previous operation. The average duration of follow up was 26 (12-56) months. 6 patients had been treated with the previous operation that 3 patients with drilling, 3 patients excision, curettage and drilling. Results: The average AOFAS Ankle/Hindfoot score was 92.7 points and no patient had a limitation of the daily activities due to pain or abnormal function. Postoperative radiography showed good joint congruency and postoperative MRI good incorporation of the graft. The average Lysholm knee score was 96 points and only two patients had mild knee pain during severe exertion. Conclusion: The autologous osteochondral grafting is the useful operative method when the lesion is advanced stage or when previous operative treatment has failed.

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The Efficacy of Simultaneous Breast Reconstruction and Contralateral Balancing Procedures in Reducing the Need for Second Stage Operations

  • Smith, Mark L.;Clarke-Pearson, Emily M.;Vornovitsky, Michael;Dayan, Joseph H.;Samson, William;Sultan, Mark R.
    • Archives of Plastic Surgery
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    • v.41 no.5
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    • pp.535-541
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    • 2014
  • Background Patients having unilateral breast reconstruction often require a second stage procedure on the contralateral breast to improve symmetry. In order to provide immediate symmetry and minimize the frequency and extent of secondary procedures, we began performing simultaneous contralateral balancing operations at the time of initial reconstruction. This study examines the indications, safety, and efficacy of this approach. Methods One-hundred and two consecutive breast reconstructions with simultaneous contralateral balancing procedures were identified. Data included patient age, body mass index (BMI), type of reconstruction and balancing procedure, specimen weight, transfusion requirement, complications and additional surgery under anesthesia. Unpaired t-tests were used to compare BMI, specimen weight and need for non-autologous transfusion. Results Average patient age was 48 years. The majority had autologous tissue-only reconstructions (94%) and the rest prosthesis-based reconstructions (6%). Balancing procedures included reduction mammoplasty (50%), mastopexy (49%), and augmentation mammoplasty (1%). Average BMI was 27 and average reduction specimen was 340 grams. Non-autologous blood transfusion rate was 9%. There was no relationship between BMI or reduction specimen weight and need for transfusion. We performed secondary surgery in 24% of the autologous group and 100% of the prosthesis group. Revision rate for symmetry was 13% in the autologous group and 17% in the prosthesis group. Conclusions Performing balancing at the time of breast reconstruction is safe and most effective in autologous reconstructions, where 87% did not require a second operation for symmetry.

Visual Disturbance following Autologous Fat Injection into Periorbital Area (안와부 자가지방이식술 후 시력 저하에 대한 증례보고)

  • Jeon, Young Woo;Kim, Sung Soo;Ha, Sang Wook;Lee, Young Dae;Seul, Chul Hwan;Tark, Kwan Chul;Cho, Eul Jae;Yoo, Won Min
    • Archives of Plastic Surgery
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    • v.34 no.5
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    • pp.663-666
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    • 2007
  • Purpose: Autologous fat injection into the facial area is a frequently used technique in aesthetic plastic surgery for augmentation of the soft tissue. Fat injection is a very safe procedure because of the advantage of being autologous tissue. Minimal foreign body reaction or infections are noted after fat injection. However, there may be some complications including those as severe as blindness. There have been some case reports on visual disturbances after autologous fat injection reported in the literature. Methods: A 21-year-old female patient underwent autologous fat injection into left eyebrow area to correct depression of soft tissue. Immediately after injection of autologous fat, she complained sudden visual loss on the left eye. She had come to our emergency room and ophthalmologic evaluation showed that the patient could only recognize hand motion. There was no abnormality of the optic nerve on magnetic resonance imaging. Suspecting an ischemic optic neuritis from fat embolism of the central retinal artery, the patient was treated conservatively with occular massage, antiglaucomatic agent, anti-inflammatory drugs and antibiotics. Visual field examination showed visual defect of half the lower hemisphere. Results: While maintaining antiglaucomatic agents and non steroidal anti inflammatory drugs, fundoscopic examination showed no abnormalities on the second day of admission. Visual field examination showed an improvement on the fourth day along with decreased eyeball pain. Significant improvement of vision was noted and the patient was discharged on the fifth day of admission. The patient was followed-up 2 days afterwards with improved vision and visual field defect. Conclusion: We describe an unusual case of sudden unilateral visual disturbance following autologous fat injection into periorbital area.

Histology of Injected Autologous Auricular Cartilage in the Paralyzed Canine Vocal Fold at Two Year (실험적 성대마비 개에서 자가이개연골의 성대근육내 주입 후 조직학적 변화 : 2년 후 결과)

  • Lee Byung-Joo;Lee Jin-Choon;Chon Kyong-Myong;Goh Eui-Kyung;Roh Hwan-Jung;Lee Chang-Hun;Wang Soo-Geun
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.16 no.2
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    • pp.113-117
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    • 2005
  • Background and Objective : Vocal fold augmentation by injectable material under direct visual control is an easy and simple operation. However, when autologous fat or bovine collagen is used, the resoiption creates a problem. And autologous fascia is debating about absorption now days. We previously reported on the one year results of injected autologous auricular cartilage for volumetric augmentation in paralyzed canine vocal cord. This study evaluates the long-term histomorphologic results of injected autologous auricular cartilage for the augmentation of the paralyzed canine vocal fold at two year. Material and Methods . A prospective trial of autologous cartilage augmentation of vocal cord in animal model. Three dogs were operated upon. A piece of auricular cartilage was harvested from the ear and minced into tiny chips with a scalpel. Fat was harvested from inguinal area and minced with a scalpel. The minced cartilage and fat-paste (0.2ml) was injected using a pressure syringe into the paralyzed thyroarytenoid muscle using direct laryngoscopy. Three animals were sacrificed at 2 years. Each subject underwent laryngectomy and serial coronal sections of paraffin blocks from the posterior vocal fold were made. Results There was no significant complication perioperatively and during follow-up. The injected cartilage which appeared to have lost viability existed in the vocalis muscles until 24 months. Fibrotic change was exhibited in the surrounding injected cartilage. Conclusion : The autologous auricular cartilage graft is well tolerated and may be very effective material for volumetric augmentation on paralyzed vocal cord.

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TISSUE REACTION IN RESPONSE TO AUGMENTATION OF SOFT TISSUE DEFECTS ACCORDING TO THE DERMIS GRAFT MATERIALS IN RABBITS (연조직 결손을 일으킨 가토에서 진피 이식재에 따른 조직반응 비교)

  • Ha, Hyun;Kim, Sun-Kook;Ryu, Sun-Youl
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.2
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    • pp.114-120
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    • 2007
  • The augmentation of soft tissue defects is one of the critical problems in the oral and maxillofacial surgery. Various types of graft materials, both autologous and non-autologous, have been used for the augmentation of soft tissue in the facial region. However, it is not easy to choose an ideal material for soft tissue augmentation because each has its advantages and disadvantages. An ideal graft material should meet the following criteria : it should not leave a scar at the area from which it was taken; should have less likelihood of causing infection; should feel natural after implanted; and should be not absorbed. Among the materials meeting these criteria, human dermis and artificial dermis are commonly used for clinical purposes. The present study was aimed to investigate and compare the resorption rate and the histological change following the use of the autologous dermis, the human homogenous dermis $Alloderm^{(R)}$, and the artificial dermis $Terudermis^{(R)}$ to reconstruct the soft tissue defect. Twenty mature rabbits of either sex, weighing about 2 ㎏, were used. Each rabbit was transplanted with the autologous dermis, $Alloderm^{(R)}$, and $Terudermis^{(R)}$ size $1{\times}1-cm$ at the space between the external abdominal oblique muscle and the external abdominal oblique fascia. They were then divided into 4 groups (n=5 each) according to the time elapsed after the surgery: 1, 2, 4, and 8 weeks. The resorption rate was calculated by measuring the volume change before and after the transplantation, and H-E stain was preformed to observe the histological changes. The resorption rate after 8 weeks was 21.5% for the autologous dermis, 16.0% $Alloderm^{(R)}$, and 36.4% $Terudermis^{(R)}$, suggesting that $Alloderm^{(R)}$ is the most stable while $Terudermis^{(R)}$ is the most unstable. In microscopic examinations, the autologous dermis graft was surrounded by inflammatory cells and showed foreign body reactions. The epidermal inclusion cyst was observed in the autologous dermis graft. $Terudermis^{(R)}$ and $Alloderm^{(R)}$ demonstrated neovascularization and the progressive growth of new fibroblast. The results suggest that $Terudermis^{(R)}$ and $Alloderm^{(R)}$ can be availably for substituting the autologous dermis.