• Title/Summary/Keyword: Autoimmune Hemolytic Anemia(AIHA)

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Retrospective Clinical Analysis of Treatment for Primary Warm Autoimmune Hemolytic Anemia (원발성 온난자가면역용혈빈혈의 치료에 대한 후향적 분석)

  • Moon, Hong Seop;Park, Chiyoung
    • Korean Journal of Clinical Pharmacy
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    • v.25 no.3
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    • pp.166-170
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    • 2015
  • Background: Primary warm autoimmune hemolytic anemia (AIHA) is a relatively rare hematologic disorder resulting from autoantibody production against red blood cells. There has been very few studies about primary warm AIHA in South Korea because of its low incidence. We retrospectively analyzed the treatment outcome of primary warm AIHA. Method: We reviewed retrospectively the medical records of 9 primary warm AIHA patients from December 2002 to January 2015. We analyzed the causes and clinical characteristics of primary warm AIHA patients. We retrospectively analyzed the clinical data in electronic medical records for 9 Korean patients with AIHA patients who were diagnosed during the period from December 2002 to January 2015 at the Regional University Hospital in Korea. The study protocol was approved by the Institutional Review Board (IRB #2015-08-007, Chosun University Hospital IRB). Results: The mean age was 52 years (range 27~78), the mean hemoglobin level was 5.0 g/dL (range 2.5~6.4 g/dL). All patients received steroids at therapeutic dosages (corticosteroid 1 mg/Kg) as first line treatment. Eight of them showed complete response (5/8, 62.5%) and partial response (3/8, 37.5%), one patient required second-line treatment with rituximab. Two patients who responded first line treatment were relapsed at 86 weeks and 24 weeks after response, respectively. Only one patient of them was retreated with corticosteroid because of anemic symptoms. Conclusion: This study indicates that oral corticosteroid is an effective therapy for primary warm AIHA.

A Case of Evans Syndrome Treated through Oriental Medicine (한방적 치료 접근을 통한 Evans 증후군 치험 1례)

  • Park, Sang-Eun;Choi, In-Sun;Jang, Ja-Won;Hong, Sang-Hoon;Seo, Sang-Ho
    • The Journal of Internal Korean Medicine
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    • v.25 no.3
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    • pp.573-581
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    • 2004
  • Evans syndrome, as originally described, refers to autoimmune hemolytic anemia accompanied by thrombocytopenia. The autoantibodies in Evans syndrome are directed specifically against red cells, platelets, or neutrophils and are not crossreacting. The incidence of autoimmune hemolytic anemia is estimated to be approximately 10 cases per million people. Many patients have associated disorders, such as lupus erythematosus and other autoimmune disease, chronic lymphadenopathy, or hypogammaglobulinemia. In Oriental Medicine, the approach to Evans syndrome is made in view of deficiency of blood. The ailment was treated through methods of Oriental Medicine. Acupucture and herbal medicine were administered to patients diagnosed with Evans Syndrome by ecchymosis at the lower limb after continued gingival bleeding. As a result significant improvement in RBC, Hb, Hct, and PLT were observed and complaints abated.

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Clinical Report on the Patients Suffering from Neurogenical Bladder (신경인성 방광 환자 치험 2례)

  • Yu, Byeong-Chan;Han, Yeong-Ju;Chae, Eun-Yeong;Yun, Dam-Hee;Lee, Nam-Hun;Cho, Chung-Sik;Kim, Chul-Jung;Lee, Ji-Yeong
    • The Journal of Internal Korean Medicine
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    • v.25 no.3
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    • pp.677-683
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    • 2004
  • The following case studies illustrate the application of oriental medical treatment of patients diagnosed with neurogenical bladder. The outstanding symptoms of two cases were general weakening and voiding difficulty, urinary retention and lack of urine sense. In one case, neurogenical bladder was caused by an operation on the femur, and in the other case, by diabetes and anemia. Western medical treatment didnot have any effect in these cases, but after oriental medical treatment, self-voiding was possible. These resu1t suggest that oriental treatment should be considered for patients with neurogenical bladder.

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A Case report of ascites in Liver cirrhosis treated with Taeumjowetang-gamibang (태음조위탕가미방(太陰調胃湯加味方)으로 복수를 동반한 간경변 환자 치험 1례)

  • Kim, Jung-Chul;Lee, Hae-Yeon;Park, Jung-Han;Lee, Jae-Jun;Lee, You-Kyung;Han, Dong-Youn;Cho, Hyun-Seok
    • The Journal of Internal Korean Medicine
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    • v.25 no.3
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    • pp.625-632
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    • 2004
  • Liver cirrhosis is a disease of the liver in which normal cells are replaced by scar tissue. This condition results in the failure of the liver to perform many of its usual functions. Liver cirrhosis include acsites, jaundice, portal hypertension, varices etc. This report is about one case of ascites with liver cirrhosis. In this case, we administrated Taeumjowetang-gamibang was administered and acupuncture was done in treatment of ascites and its symptoms. After administration of Taeumjowetang-gamibang medication, clinical symptoms and prominently improved and ascites dwindled to nothing. This reports suggests Taeumjowetang-gamibang has desirable effected on ascites.

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