• Title/Summary/Keyword: Auto injector

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Effect of Fuel Nozzle Configuration on the Reduction of NOx Emission in Medium-speed Marine Diesel Engine (연료분사 노즐 형상이 선박용 중형 디젤 엔진의 NOx에 미치는 영향 연구)

  • Yoon, Wook-Hyeon;Kim, Byong-Seok;Ryu, Sung-Hyup;Kim, Ki-Doo;Ha, Ji-Soo
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2005.11a
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    • pp.13-14
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    • 2005
  • Multi-dimensional combustion analysis and experiment has been carried out to investigate the effects of the injector nozzle hole diameter and number on the NOx formation and fuel consumption in HYUNDAI HiMSEN engine. The behavior of spray and combustion phenomena in diesel engine was examined by FIRE code. Wave breakup and Zeldovich models were adopted to describe the atomization characteristics and NOx formation. Wallfilm model suggested by Mundo, et al. and auto-ignition model suggested by Theobald and Cheng were adopted to investigate the spray-wall interaction characteristics and ignition delay. The information of spray angle and spray tip penetration length was extracted from fuel spray visualization experiment and the fuel injection rate profile was extracted from fuel injection system experiment as an input and verification data for the combustion analysis. Next, the nine different nozzle configurations were simulated to evaluate the effect of injector hole diameter and number on the NOx formation and fuel consumption.

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Improving Adherence to Growth Hormone (GH) Therapy via EasypodTM May Help Maximize the Treatment Outcome

  • Choi, Hae-Jeong
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.1 no.1
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    • pp.19-22
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    • 2015
  • In Growth Hormone (GH) therapy, suboptimal adherence is a common problem, reaching up to 82%, and there is a need for interventions to improve adherence and to maximize patients' growth potential eventually. Current studies have demonstrated the association between the rate of non-adherence and reduced height velocity. In order to maximize patients' potential to grow, an auto-injecting/recording device, such as $easypod^{TM}$, may help improve adherence and optimize the treatment effects of GH therapy. The use of $easypod^{TM}$ has contributed to high adherence rates: 87.5% and 93% in Bozzola et al.'s study and the $Easypod^{TM}$ Connect Observational study (ECOS), respectively. Improvement of adherence by $easypod^{TM}$ may lead to higher growth rates of patients receiving GH therapy. Additionally, patients' positive acceptability of $easypod^{TM}$ suggests $easypod^{TM}$ is a preferred device by patients for better adherence.

Development of RF Ion Source for Neutral Beam Injector in Fusion Devices

  • Jang, Du-Hui;Park, Min;Kim, Seon-Ho;Jeong, Seung-Ho
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.550-551
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    • 2013
  • Large-area RF-driven ion source is being developed at Germany for the heating and current drive of ITER plasmas. Negative hydrogen (deuterium) ion sources are major components of neutral beam injection systems in future large-scale fusion experiments such as ITER and DEMO. RF ion sources for the production of positive hydrogen ions have been successfully developed at IPP (Max-Planck- Institute for Plasma Physics, Garching) for ASDEX-U and W7-AS neutral beam injection (NBI) systems. In recent, the first NBI system (NBI-1) has been developed successfully for the KSTAR. The first and second long-pulse ion sources (LPIS-1 and LPIS-2) of NBI-1 system consist of a magnetic bucket plasma generator with multi-pole cusp fields, filament heating structure, and a set of tetrode accelerators with circular apertures. There is a development plan of large-area RF ion source at KAERI to extract the positive ions, which can be used for the second NBI (NBI-2) system of KSTAR, and to extract the negative ions for future fusion devices such as ITER and K-DEMO. The large-area RF ion source consists of a driver region, including a helical antenna (6-turn copper tube with an outer diameter of 6 mm) and a discharge chamber (ceramic and/or quartz tubes with an inner diameter of 200 mm, a height of 150 mm, and a thickness of 8 mm), and an expansion region (magnetic bucket of prototype LPIS in the KAERI). RF power can be transferred up to 10 kW with a fixed frequency of 2 MHz through a matching circuit (auto- and manual-matching apparatus). Argon gas is commonly injected to the initial ignition of RF plasma discharge, and then hydrogen gas instead of argon gas is finally injected for the RF plasma sustainment. The uniformities of plasma density and electron temperature at the lowest area of expansion region (a distance of 300 mm from the driver region) are measured by using two electrostatic probes in the directions of short- and long-dimension of expansion region.

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Food allergy knowledge, perception of food allergy labeling, and level of dietary practice: A comparison between children with and without food allergy experience

  • Choi, Yongmi;Ju, Seyoung;Chang, Hyeja
    • Nutrition Research and Practice
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    • v.9 no.1
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    • pp.92-98
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    • 2015
  • BACKGROUND/OBJECTIVES: The prevalence of food allergies in Korean children aged 6 to 12 years increased from 10.9% in 1995 to 12.6% in 2012 according to nationwide population studies. Treatment for food allergies is avoidance of allergenic-related foods and epinephrine auto-injector (EPI) for accidental allergic reactions. This study compared knowledge and perception of food allergy labeling and dietary practices of students. SUBJECTS/METHODS: The study was conducted with the fourth to sixth grade students from an elementary school in Yongin. A total of 437 response rate (95%) questionnaires were collected and statistically analyzed. RESULTS: The prevalence of food allergy among respondents was 19.7%, and the most common food allergy-related symptoms were urticaria, followed by itching, vomiting and nausea. Food allergens, other than 12 statutory food allergens, included cheese, cucumber, kiwi, melon, clam, green tea, walnut, grape, apricot and pineapple. Children with and without food allergy experience had a similar level of knowledge on food allergies. Children with food allergy experience thought that food allergy-related labeling on school menus was not clear or informative. CONCLUSION: To understand food allergies and prevent allergic reactions to school foodservice among children, schools must provide more concrete and customized food allergy education.

An Investigation on Spray Characteristics of Diesel - DME with Change of Injection Pressure (분사압력 변화에 따른 디젤-DME연료의 다단분사 특성에 관한연구)

  • Jeong, Y.H.;Yang, J.W.;Oh, C.H.;Lim, O.T.
    • Journal of ILASS-Korea
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    • v.18 no.4
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    • pp.188-195
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    • 2013
  • An investigation on spray characteristics of fuels which diesel and di-methyl ether (DME) with change of injection pressure used the multi-injection in constant volume combustion chamber (CVCC). Diesel was already used famous fuel which we could use. DME showed similar features with diesel like as cetane number, auto-ignition temperature. High cetane number of diesel and DME could make possible to compression ignition. DME showed different atomization from diesel due to evaporating pressures and boiling points. Experiments were carried out in CVCC equipped with Delphi solenoid 6-hole type injector and the spray characteristics of diesel and DME were tested the various pre and pilot injection. Terms of injections and a number of injections in multi-injection has been controlled. Experiments were performed in 2 types that 1500 rpm, 2000 rpm and under the condition of injection ranging from 100 bar to 500 bar. From the results of this experiment diesel showed longer spray penetration than DME. That result showed different of atomization speed DME and diesel. Result of high injection pressure condition showed similar spray characteristics diesel and DME. After this investigation, new conditions and experiments using laser light to go forward and add the fuels like as the biodiesel and diesel and DME blend.

Performance and Emission Characteristics of Compression Ignition Gasoline Engine (압축점화 가솔린기관의 성능 및 배기특성)

  • Kim, Hong-Sung;Kim, Mun-Heon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.27 no.7
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    • pp.1007-1014
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    • 2003
  • This work deals with a controlled auto-ignition (CAI) single cylinder gasoline engine, focusing on the extension of operating conditions. The fuel is injected indirectly into electrically heated inlet air flow. In order to keep a homogeneous air-fuel mixing, the fuel injector is water-cooled by a specially designed coolant passage. Investigated are the engine performance and emission characteristics under the wide range of operating conditions such as 32 to 63 in the air-fuel ratio, 1000 to 1800 rpm in the engine speed, and 150 to 18$0^{\circ}C$ in the inlet air temperature. The compression ignition gasoline engine can be achieved that the ultra lean-burn with self-ignition of gasoline fuel by heating inlet air. For example. the allowable lean limit of air-fuel ratio is extended until 63 at engine speed of 1000 rpm and inlet air temperature of 17$0^{\circ}C$. It can be achieved that the emission concentrations of carbon monoxide, hydrocarbons and nitrogen oxide had been significantly reduced by CAI combustion compared with conventional spark ignition engine.

A Case Study on the FDA Approval of Medical Treatments against Nerve Agent Poisoning (신경작용제 해독제 의약품 품목허가 사례 연구)

  • Lee, Keunwoo;An, Seoyeon;Hur, Byungil
    • Journal of the Korea Institute of Military Science and Technology
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    • v.19 no.1
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    • pp.119-126
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    • 2016
  • The US Army used MARK-1 composed of atropine autoinjector and 2-PAM autoinjector as a medical countermeasure against nerve agent poisoning. Recently, it has been being replaced by the ATNAA(Antidote Treatment Nerve Agent AutoInjector) for improvement the convenience in use and rapid detoxification effect. ATNAA(FDA approval, NDA 21-175, 2002. 1. 17) is a multi-chambered autoinjector that sequentially delivers atropine and 2-PAM through a single needle to allow Warfighters to survive against lethal exposure to nerve agents. In this paper, our group investigated the case of FDA approval of ATNAA in a point of the various data required by FDA guideline, thereby making it easy to meet the KFDA guideline for the approval of the prototype our group has been developed. The purpose of this study is to provide a reference for efficient research activities to minimize time and cost. Additionally, the purpose of this study is to provide a reference for the planning for the development of similar drug.

An Experimental Study for Performance Evaluation in Dogs of Preventive Contrast Media Extravasation with a Strain Gage Based Prototype Extravasation Detection Accessory System (잡견에서 조영제 혈관외유출 예방을 위한 스트레인 게이지 기반의 EDA 시스템 성능 평가를 위한 실험적 연구)

  • Kweon, D.C.;Yoo, B.G.;Lee, J.S.;Cho, M.S.;Yang, S.H.
    • Journal of Biomedical Engineering Research
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    • v.29 no.1
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    • pp.66-72
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    • 2008
  • The major risk associated with the use of automated power injectors is the well known complication of contrast material extravasation at the injection site. Automated injection of computed tomography (CT) contrast media can produce the compartment syndrome. The purpose of this study was to assess the ability of this device during clinically important episodes of extravasation. The extravasation detection accessory (EDA) system was composed of a strain gage, an amplifier and a computer based system. A strain gage pliable adhesive patch was applied to the skin aver the intravenous catheter and the catheter was connected to the power injector with a cable to monitor the resolution data. If the programmed monitoring, which was developed with MS Visual C++, at the extravasation occurred, then the injection was interrupted the auto injector. CT was used to demonstrate the clinically important extravasation. This study was a prospective, observational study in which the EDA system was used to monitor the automated mechanical injection of contrast material in 7 dogs. There were two true-positive cases (range of extravasation volumes: $18{\sim}22ml$), twenty three true-negative cases, three false-positive cases and no false-negative cases. The EDA system had a sensitivity of 100% and a specificity of 88% for the detection of clinically important extravasation. The EDA system had good sensitivity for the detection of clinically important extravasation and the EDA system has the clinical potential for the early detection of extravasation of the contrast medium that is administered with power injectors. The EDA system is easy to use safe and accurate for the monitoring extravasation of the intravenous injections, and this system may prove especially useful in CT applications.

Syringe Reuse Issues in Automated Contrast Injection System in Dynamic Magnetic Resonance Imaging (조영제 자동주입기를 활용한 자기공명영상 동적검사 시 실린지 재사용의 문제)

  • Son, Soon-Yong
    • The Journal of the Korea Contents Association
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    • v.19 no.11
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    • pp.445-450
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    • 2019
  • This study proves that syringe reuse of automated injection system entails a risk of contrast media reflux and saline solution contamination which are pumped by a piston into the patients' venous cannula in the dynamic MR images, we will be aware of the serious problem. To quantify the contrast media contamination effect on the saline solution, identical volume of the saline solution was collected before and after the contrast injection to the patients' venous cannula following T1 weighted image scanning to verify whether signal intensities differences are observed. The signal intensity of saline solution after the contrast injection was significantly higher than that of saline before injection by 523.43%. This result is due to the backflow that contaminates the saline solution on the opposite side when the contrast agent is injected. In conclusion, the syringe used to inject contrast medium. causes cross-contamination due to contrast reflux. Therefore, even if the same patient's examination is used for quantitative analysis, the error should be avoided by changing the acquisition sequence or replacing the syringe.

A study on Hemo-Dynamic information Within 30 seconds in DCE 3D Breast MRI : Experienced Reports (DCE 3D Breast MRI 검사 시 30 sec 이내에 혈류 역학적 정보에 대한 연구 : Experienced Reports)

  • Goo, Eun-Hoe
    • Korean Journal of Digital Imaging in Medicine
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    • v.16 no.1
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    • pp.27-33
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    • 2014
  • The purpose of this study evaluated the hemo-dynamic information within 30 seconds clinically in 3D breast MRI. From January to March 2014, A total of 40 people were examined at 1.5 Tesla(Philips, Medical System, Achieva, The Netherlands) MRI equipments using 16 channel SENSE breast coil. The imaging parameters on vibrant are fellow as: $TR/TE/FA^{\circ}$/Matrix size/Slice thickness/Slab($5ms/2ms/10^{\circ}/180{\times}139{\times}2mm/80$). This study used a Gadovist and injected it with injection speed of 4 ml /sec by auto injector with 15 ml saline flushing. Firstly, for the delay time study, it divided three different delay time from immediately, 20 seconds, and 30 seconds. In quantitative analysis, the ROI signal intensities of tumor and surrounding tissues were measured retrospectively. In qualitative analysis, the image quality was scored from 1 to 5 point by one experienced radiological technologists as a visual test. The significance level of each delay time was evaluated with a one-way ANOVA(p<0.05). In the visual test, score levels on 30 seconds delay time was a little bit higher than others(p<0.05). The signal intensity of the tumor were $1445{\pm}360$, $1410{\pm}320$, $1510{\pm}415$ on immediately, 20 seconds, and 30 seconds and score levels were $4.18{\pm}0.85$, $3.54{\pm}0.94$, $4.45{\pm}0.74$(p<0.05). The data on immediate images showed better results than that others(p<0.05). Conclusively, Although it has been high scored in 30sec delay time for visual test in order to avoid failure in 20second, 30seconds delay time after contrast media administration, we recommend that the DCE 3D breast MRI commence immediately.

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