• Journal of Trauma and Injury
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• 제28권4호
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• pp.223-231
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• 2015

Purpose: Delayed, traumatic, intraparenchymal hemorrhage (DTIPH) is a well-known contributing factor to secondary brain damage that evokes severe brain edema and intracranial hypertension. Once it has occurred, it adversely affects the patient's outcome. The aim of this study was to evaluate the prognosis factors for DTIPH by comparing clinical, radiological and hematologic results between two groups of patients according to whether surgical treatment was given or not. Methods: The author investigated 26 patients who suffered DTIPH during the recent consecutive five-year period. The 26 patients were divided according to their having undergone either a decompressive craniectomy (n=20) or continuous conservative treatment (n=6). A retrospective investigation was done by reviewing their admission records and radiological findings. Results: This incidence of DTIPH was 6.6% among the total number of patients admitted with head injuries. The clinical outcome of DTIPH was favorable in 9 of the 26 patients (34.6%) whereas it was unfavorable in 17 patients (65.4%). The patients with coagulopathy had an unexceptionally high rate of mortality. Among the variables, whether the patient had undergone a decompressive craniectomy, the patient's preoperative clinical status, and the degree of midline shift had significant correlations with the ultimate outcome. Conclusion: In patients with DTIPH, proper evaluation of preoperative clinical grading and radiological findings can hamper deleterious secondary events because it can lead to a swift and proper decompressive craniectomy to reduce the intracranial pressure. Surgical decompression should be carefully selected, paying attention to the patient's accompanying injury and hematology results, especially thrombocytopenia, in order to improve the patient's neurologic outcomes.

• 한국전자파학회논문지
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• 제7권1호
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• pp.61-70
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• 1996

M-ary DPSK는 대역 효율이 우수한 디지탈 변조 기법이고, 최큰에는 이용 가능한 무선 대역폭이 제한된 이동 위성통신 시스댐 분야의 응용에서 관심이 모아지고 있다. 동기 검파 방식은 잡음 환경에서 우수한 오류 성능을 제공하지만 페이딩 환경에서는 낀 포착 시간을 필요로 한다.본 논문에서는 라이시안 페이딩과 쉐도우 라이시안 페이딩 채널에서 다중 차동 궤환 검파 기법을 사용한 M-ary DPSK 신호의 오류 성능을 분석하였다. 다중 차동 궤환 검파 기법은 일반적인 차동 수신기의 복잡도를 증가시켜서 차동 수신과 동기 수선 사이의 성능 차이를 줄일 수 있는 효율적인 기법이다. 다중 심볼 최대 우도 검파 기법과 비교할 때 다중 차동 궤환 검파 기법은 H/W 구현상에서 매우 간단한 구조를 갖는다. 특히 이 기법은 잡음과 빠른 페이딩 채널 사이에서 시간과 공간에서 변할 수 있는 육상 이동위성 채널에 적용할 수 있다.

• STI Policy Review
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• 제5권1호
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• pp.75-97
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• 2014

Entrepreneurial financing, such as publicly initiated venture capital or grant schemes, serves as an important policy instrument that aims to bridge the financing gap facing young, innovative businesses, a gap that is mainly due to higher risk and growing uncertainty, and to strategically promote the creation of new ventures through the revitalization of their venture capital industries. This study examines public venture capital initiatives in Australia, Canada, and Sweden, and discovered that all three countries actively foster their venture capital industry through the formation of funds or the provision of tax incentives. It is notable that the majority of financing initiatives heavily depend on supply-side measures rather than demand-driven policies that focus on stimulating private investment in technological innovations and discoveries. This paper discusses in-depth the policy impact of public financing initiatives and their subsequent side-effects raised in the process such as overlapping in funding structure across the country, lack of monitoring and evaluation for feedback, fragmentation across the government ministries and agencies, and competition with the private sector, which may cause inefficiency as a result of public intervention. Financial constraints may arise for many reasons, partly resulting from the lack of investment readiness of young entrepreneurs. This signals a policy shift towards the creation of market-driven demand away from the traditional supply-push approach, and is a grand challenge to policymakers in entrepreneurial financing. Attention is leaning towards the efficiency and effectiveness of these public-financing initiatives in terms of their policy roles. It is worth noting that policy should focus on generating synergy so available resources can be channeled into the early, risky stage of new ventures, working as facilitator to the achievement of an intended policy goal.

• Journal of Ginseng Research
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• 제31권1호
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• pp.34-43
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• 2007

Background: Previous research has suggested that single doses of a standardised Panax ginseng extract can decrease fasted blood-glucose levels and modulate cognitive performance in healthy young volunteers. The latter has generally been seen in terms of improved secondary memory performance. However, both the cognitive effects of chronic administration of ginseng and the potential modulation of working memory have received comparatively little research attention. Aims: The current double-blind, placebo-controlled, balanced cross-over study investigated the effects of 8-weeks administration of Korean ginseng extract (200 mg) on cognitive performance, gluco-regulatory parameters and ratings of subjective mood and 'quality of life'. Methods: 'Eighteen healthy young participants were assessed pre-dose and 3 hours post-dose on the mornings of Day 1, Day 29 and Day 57 of 8 week treatment regimens of both placebo and ginseng. A four-week placebo wash-out separated the treatment phases. Each assessment included the Cognitive Drug Research battery, computerised working memory tasks, and Bond-Lader mood scales. The WHO Quality of Life scale (WHOQOL-BREF) was completed once per visit. Gluco-regulatory parameters were assessed with assays of blood glucose, insulin and HbA1c. Results: Data from the 16 participants that completed the study showed that there were no significant, acute treatment related differences on Day 1 of treatment, or in gluco-regulatory parameters throughout the study. However, time related performance improvements were evident following chronic administration of ginseng on the '3-Back' and 'Corsi-block' computerised working memory tasks. Ginseng was also associated with an improved score on the 'social relations' subscale of the WHOQOL-100, and a significant shift on the 'calm' factor of the Bond-Lader mood scales (from calm/relaxed towards excited/tense). Conclusion: The results of the current study suggest that Korean ginseng extract can modulate working memory performance and subjective ratings of 'quality of life' and mood. Replication with a larger sample size may further elucidate the actions of this product.

• 보건행정학회지
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• 제24권4호
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• pp.396-412
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• 2014

Background: As a reform plan of health care system, Accountable Care Organization (ACO) has became an object of attention in the United States after Patient Protection and Affordable Care Act was enacted. ACO is a group of various health care providers and provide coordinated care to its assigned beneficiaries. If ACOs improve the quality level and reduce the cost of care, they can get financial incentives. Under the discussion for a quite long time and demonstration projects, ACO has been established. We aimed to analysis and discuss the history, policy mechanism, contents, status and outcomes of ACO. Also, we intended to suggest political implication Korean health care system with regard to ACO. Methods: We searched the articles related ACO in PubMed and selected several available papers about ACO. Total 56 studies were reviewed and categorized three parts; demonstration projects for formation of ACO, policy mechanism and agenda, empirical results of ACO performance. Results: As a result, establishment of ACO was successful partly in the US. It seems to be due to various project and pilot test for verification in the long time. The empirical effect of ACO was also identified in a few study but it needs more evidences to judge its positive effect. Conclusion: In Korea, there are arguments for the application of ACO. However it is difficult to implement a ACO by different political conditions between Korean and US. Nevertheless ACO proposed us the necessity of paradigm shift in our health policy and could be significant to national policy orientation in the future.

• 한국가구학회지
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• 제26권4호
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• pp.456-466
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• 2015

Today, a definition of tourism is shifting from simple sightseeing to experiencing various cultures directly and/or indirectly. Along with the shift, all countries of the world dedicate their full attention on globalization project. In order to do so, they try to promote their images and cultures through eating and drinking spaces for food where the rest of the world can approach with ease. China is a country of diverse culinary culture. By analyzing eating and drinking spaces operated in four Chinese cities, this research studies how the traditional Chinese elements are expressed in modernization. With the research, it will navigate a direction as a new design way to establish modernized traditionality in the future. The research conducted an advanced research that set up and analyzed a standard frame of realizing practice for traditionality. By doing so, it sorted out and reviewed the characteristics of interior space into four styles; an indicative imitation method, a partial invoked method, a partial transformation method and a conceptual reception method. According to the outcome of an analysis, (a) the indicative imitation method that directly employed Chinese tradition was most used one, followed by (b) the partial invoked method that carried a part of traditional space, (c) the partial transformation method that simplified or transformed the tradition, and (d) the conceptual reception method that interpreted hidden minds and concepts by illustrating modern spirit over an inherent order in traditional Chinese space, in respective order.

• 한국언론정보학보
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• 제30권
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• pp.175-201
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• 2005

본 논문은 '다양성'이라는 규범적 가치에 입각해 뉴스 기사 선별 및 취재 경로와 관련한 미 신문의 뉴스 제작 방식에는 어떤 변화가 진행돼 왔는지를 통시적으로 살펴보고 있다. 이에 따라 본고에서는 '뉴스 토픽'과 '정보원' 등 두 가지 분야에서 지난 50년간 뉴욕 타임스와 시카고 트리뷴, 로스앤젤레스 타임스 등 3대 유력 일간지의 1면 기사를 분석, 연대기적인 가치 변화를 추적해 보았다. 데이터 분석 결과, 지난 반세기 동안 미 신문에서 정부 및 정치권에 대한 정보원의 의존도는 지속적으로 줄어들고 있는 반면, 기업/산업체발 정보원의 등장은 점차 빈번해 지고 있는 것으로 나타났다. 이와 함께, 뉴스 주제의 분포에 있어서는 사건, 사고 기사의 감소와 군사, 안보기사의 퇴조 속에, 경제, 건강, 교육 등과 같은 주제가 점차 활발하게 다뤄지고 있는 것으로 조사됐다. 그러나 전통적인 비인기 주제였던 빈곤, 노동, 소수자, 사회 갈등 등과 같은 토픽들은 시대를 거듭해도 제자리를 맴돌거나 오히려 줄어들고 있는 것으로 나타났다.

• Asian-Australasian Journal of Animal Sciences
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• 제14권10호
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• pp.1483-1496
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• 2001

Small ruminants form an important economic and ecological niche in small farm systems and agriculture. Their current low level of contribution is dismal, and is not commensurate with the potential capacity for higher levels of production. The context for productivity enhancement and increased socio-economic contribution relates to large sizes of small ruminant populations; wide distribution across various agro-ecological zones and production systems; and diversity of breeds, where 66% of all goat and 57% of sheep breeds in Asia are found in China, India and Pakistan. The advantages and disadvantages of small ruminants over larger ruminants are enumerated with reference to adaptation and environment, small size, production systems and products and interactions with the environment. Discussion focuses especially on efficiency of meat production and niche markets for higher-priced goat meat, and inefficient marketing systems given an estimated 40-45% loss of income to farmers presently. Increasing the quantity of meat produced is related to live weight and the total number of animals at Slaughter, which in turn, depend on the total number of offsprings weaned and lifetime productivity. At the national level, priority attention is essential to build up numbers in concerted breeding programmes, selection for efficiency of reproduction and meat production, and improvements to make traditional markets and marketing systems to respond to the changing environmental and consumer preferences. Post-production systems are neglected and improvements are associated with collection, handling, marketing, slaughter facilities and consumer requirements. Potential opportunities to expand and benefit from integrating small ruminants into annual and perennial cropping systems remain largely unexplored. Important development imperatives include choice of species and better use of available breeds, appropriate production systems that match available feed resources, and linkages between production, products and by-products to markets. Affirmative action is necessary, backed by official policy support, institutional commitment and increased resource use, that can target poverty and directly benefit the poor, and shift subsistence production to a more market-oriented opportunity. These efforts together constitute the challenges for both the owners and producers of small ruminants in the immediate future, as also the will to accelerate increased productivity, improve their livelihoods and promote rural growth.

• Natural Product Sciences
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• 제17권3호
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• pp.250-255
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• 2011

The immune system is finely balanced by the activities of pro-inflammatory and anti-inflammatory mediators or cytokines. Unregulated activities of these mediators can lead to the development of various inflammatory diseases. A variety of safe and effective anti-inflammatory agents are available with many more drugs under development. Of the natural compounds, the sesquiterpenes (nootkatone, ${\alpha}$-cyperone, valencene and ${\alpha}$-selinene) isolated from C. rotundus L. have received much attention because of their potential antiinflammatory effects. However, limited studies have been reported regarding the influence of sesquiterpene structure on anti-inflammatory activity. In the present study, the anti-inflammatory potential of four structurally divergent sesquiterpenes was evaluated in lipopolysaccaride (LPS)-stimulated RAW 264.7 cells, murine macrophages. Among the four sesquiterpenes, ${\alpha}$-cyperone and nootkatone, showed stronger anti-inflammatory and a potent NF-${\kappa}B$ inhibitory effect on LPS-stimulated RAW 264.7 cells. Molecular analysis revealed that various inflammatory enzymes (iNOS and COX-2) were reduced significantly and this correlated with downregulation of the NF-${\kappa}B$ signaling pathway. Additionally, electrophoretic mobility shift assays (EMSA) elucidated that nootkatone and ${\alpha}$-cyperone dramatically suppressed LPS-induced NF-${\kappa}B$-DNA binding activity using 32Plabeled NF-${\kappa}B$ probe. Hence, our data suggest that ${\alpha}$-cyperone and nootkatone are potential therapeutic agents for inflammatory diseases.

• KIEAE Journal
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• 제14권3호
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• pp.5-13
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• 2014

This paper introduces emergy(spelled with "m") that is a new environmental indicator in architecture, aiming to clarify conflicting claims of building design components in the process of energy-retrofit. Much of design practitioners' attention on low energy use in operational phases, may simply shift the lowered environmental impact within the building boundary to large consumption of energy in another area. Specifically, building energy reduction strategies without a holistic view starting from natural formation, may lead to the depletion of non-renewable geobiological sources (e.g. minerals, fossil fuels, etc.), which leaves a building with an isolated energy-efficient object. Therefore, to overcome the narrow outlook, this research discusses the total ecological impact of a building which embraces all process energy as well as environmental cost represented by emergy. A case study has been conducted to explore emergy-driven design work. In comparison with operational energy-driven scenarios, the results elucidate how energy and emergy-oriented decision-making bring about different design results, and quantify building components' emergy contribution in the end. An average-size ($101.9m^2$) single family house located in South Korea was sampled as a benchmark case, and the analysis of energy and material use was conducted for establishment of the baseline. Adoption of the small building is effective for the goal of study since this research intends to measure environmental impact according to variation of passive design elements (windows size, building orientation, wall materials) with new metric (emergy) regardless of mechanical systems. Performance simulations of operational energy were developed and analyzed separately from the calculation of emergy magnitudes in building construction, and then the total emergy demand of each proposed design was evaluated. Emergy synthesis results verify that the least operational energy scenario requires greater investment in indirect energy in construction, which clearly reveals that efficiency gains are likely to be overwhelmed by increment of material flows. This result places importance on consideration of indirect energy use underscoring necessity of emergy evaluation towards the environment-friendly building in broader sense.