• Journal of Oriental Medical Thermology
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• v.2 no.1
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• pp.63-66
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• 2003

Background and Purpose : Ceramic based infra-red Therapy has been effective on derma system. The purpose of this case was to know the effect of ceramic based infra-red therap therapy on atopic dematitis. Material and Methods Among initial 25 outpatients with atopic detmatitis who visited Kangnam KyungHee Oriental hospital from Mar. 2000 to Sep. 2002, we excluded 4 outpatients that quited treatment after 1st treatment. We treated ceramic based infra-red therapy, herb medication treatment and Acupuncture women patients. Ceramic based infra-red therapy using GI-2000 system was lighted to under for 30 minutes. SoPungSan(消風散) was one of the effective herb medication on atopic dermatitis in oriental. In acupuncture treatment. We activated Kokchi(LI11, 曲池), Choksamni(S36, 足三里) and inhibited Yanggye(LI5, 陽谿), Yanggok(SI5, 陽谷). Results and Conclusions Ceramic based infra-red therapy, herb medication treatment and acupuncture therapy showed usfull effect on atopic dermatitis.

• The Journal of Pediatrics of Korean Medicine
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• v.23 no.2
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• pp.51-85
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• 2009

Objectives : The purpose of this study is to investigate the effect of concurrent administration of KKSDU and AJ on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the condition in humans. Methods : We evaluated clinical skin score, hematology, serum total IgE and IgG1 of NC/Nga atopic dermatitis mouse and analyzed the cytoline level, total cell number, immunohistochemical staining, histological features of axillary lymph node(ALN), draining lymph node(DLN), peripheral blood mononuclear cells(PBMCs) and dorsal skin tissue in NC/Nga mouse. Results : Orally administration of KKSDU and concurrent administration of KKSDU and AJ decreased the clinical skin score, total cell number of WBC, platelet, neutrophils, eosinophils in blood, serum total IgE & IgG1, IL-5, IL-13. Also, total cell number of ALN and dorsal skin tissue, absolute cell number of CD3e+&CD19+, CD4+&CD8+, CD3+/CCR3+, CCR3+, CD3+/CD69+, CD3+/CXCR5+ in ALN, PBMCs, absolute cell number of CCR3+, CD3+/CD69+, CD11b+/Gr-1+ in dorsal skin tissue, Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue and gene expression of IL-5 mRNA, IL-13 mRNA in ALN are significantly decreased. Furthermore, thickness of epidermis, infiltrated inflammatory immune cell & mast cell in dermis, histologic infiltration of mast cell, the size of inflammatory lymphocytes cells & plasma cells in ALN and histologic infiltration of CD4+ & CCR3+ in ALN and dorsal skin tissue are significantly decreased. However, total cell number of DLN, absolute cell number of CD3+&CD19+, CD4+&CD8+, B220+/CD23+, CD3+/CD69+ in DLN and CD4+CD25+foxp3+Treg cell, foxp3 mRNA in dersal skin tissue are increased significantly. Conclusions : Concurrent administration of KKSDU and AJ on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse was very effective to the atopic detmatitis treatment.