• Title/Summary/Keyword: Atonic

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Identification of the impurities in the technical product of Atonic (Atonic 원제의 부성분 구조 확인)

  • Kyung, Kee-Sung;Chung, Chang-Kook;Lee, Jae-Koo
    • The Korean Journal of Pesticide Science
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    • v.8 no.2
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    • pp.129-136
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    • 2004
  • In order to determine the amounts of impurities and to identify the chemical structures of the impurities in the technical product of the plant growth regulator Atonic, the extracts of diethyl ether and dichloromethane were analyzed with GC-FID and GC-MSD. resulting in detection of five impurities and identification of their chemical structures. The amount of the active ingredient atonic in the technical product was about 84% and those of the impurities ranged from 0.24 to 10.74%. The identified impurities in this technical product are 2-methoxyphenol (guaiacol, m/z 124), 2-chloro-6-methoxyphenol and/or 4-chloro-6-methoxyphenol (m/z 158), 1,2-dimethoxy-4-nitrobenzene (m/z 183), and 2,6-bis(1,1-dimethylethyl)-4-methylphenol (m/z 220), suggesting that they are not hazardous impurities.

Effects of HwangRyunHaeDok-Tang and Constituent Herbs on a Contracted Artery of Rabbit (황련해독탕(黃連解毒湯)이 가토(家兎)의 혈관긴장성조절(血管緊張性調節)에 미치는 영향(影響))

  • Nam Chang-Gyu;Kim Ho-Hyun;Jeong Chan-Gil;Sung Hyun-Jea;Kwon Oh-Yul
    • The Journal of Internal Korean Medicine
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    • v.24 no.2
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    • pp.220-232
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    • 2003
  • Objective : The purpose of this study was to analyze the effects of HwangRyunHaeDok-Tang and combinations of constituent herbs on the arterial contraction. Methods : In order to investigate the effects Scutellariae Radix. Coptidis Rhizoma, Phellodendri Cortex and Gardeniae Fructus, in which one of them, two of them, and all of them, were used to exam. Results : The results were summarized as follows; 1. HwangRyunHaeDok-Tang significantly inhibited the contraction of artery induced by Norepinephrine(NE). However the atonic effect was slightly blunted when the vascular endothelial cell was removed. No significant change in the atonic effect of HwangRyunHaeDok-Tang was found when $_L-NNA$ was used as a preliminary treatment. These results indicate that the vascular atonic effect by HwangRyunHaeDok-Tang is slightly dependent on the endothelial cell, and that the HwangRyunHaeDok-Tang works directly to the vascular smooth muscle in creating the vascular atonic effect. 2. The pretreatment of HwangRyunHaeDok-Tang extract significantly inhibited the contractile response to additive application of $Ca^{2+}$ in the strips which were contracted by NE in $Ca^{2+}$-free solution. 3. HwangRyunHaeDok-Tang extract increased the contraction of arterial smooth muscle induced by KCl. Therefore, it can be concluded that HwangRyunHaeDok-Tang may block the NE-receptor or receptor-operated $Ca^{2+}$ channel. 4. It was determined that Scutellariae Radix, Coptidis Rhizoma and Phellodendri Cortex among the ingredients of HwangRyunHaeDok-Tang have a vascular atonic effect. In addition, those ingredients plays a role in strengthening the atonic effect by working with other herbal medicines. Gardeniae Fructus causes the blood vessel to contract. but it does not influence the atonic effects of other herbal medicines. However Gardeniae Fructus tends to inhibit the vascular atonic effect of Phellodendri Cortex. Conclusion : Based on the above results, it can be said that HwangRyunHaeDok-Tang can be applied to cure hypertension considering those three herbs have significant effects of relaxation.

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A Study on Cultivation of Stevia rebaudiana Bertoni M. as an Introduced Sweetness Resource Plant in Jeju-do (새로운 감미자원식물 Stevia (Stevia rebaudiana Bertoni M.)의 재배에 관한 연구)

  • 오현도
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.22 no.2
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    • pp.112-120
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    • 1977
  • In Korea. the cultivating standard of stevia is not established yet. Because stevia is across-fertilizing plant. planting a cutting is its available propagation method. This study was made to know the effective propagation growth and adaptability of stevia in Jeju-do, according to the wintering effect and the planting density.

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Effect of Pour Into Soil and Spray on Leaves of Plant Growth Substances on the Root Out of Mulberry (식물생장물질의 토양관주와 엽면살포가 뽕나무의 발근에 미치는 영향)

  • 김문협
    • Journal of Sericultural and Entomological Science
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    • v.20 no.1
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    • pp.1-4
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    • 1978
  • The root-out of mulberry saplings has been studied by pour into soil and spray on leaves of the plant growth substances. In addition, the effect of "Rutin", a kind of plant growth hormones has been also studied on promoting the rootability of mulberry scions by dipping the scions at the various concentrations. The results are summarized as follows: (1) It is likely to be effective on acceleration of the rootability resulting in increase of rooting ratio by pour into soil at the concentration of 1 ppm and 10 ppm NAA, 10 ppm and 100 ppm Rutin, and 5000 fold solution of Atonic, respectively (2) Growth of branch is only promoted by leaf spray of 0.5% urea, 0.005% and 0.01% Rutin, and 5000 fold solution of Atonic without increasing the root weight. (3) It seems that 0.05% of Rutin is of practical use, and 0.05% to 0.4% of "Rutin" accelerates the root-out of mulberry scions as well as NAA does.

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Studies on the Preparation of Radioactive iodine Labelled Concanavalin-A, Lectin Extracted from Korean Native Plant “Banha”, and Their Conjugation Products and the Hemagglutination Tests of These Labelled Compounds in Vitro.

  • Kim, You-Sun;Park, Kyung-Bae
    • Nuclear Engineering and Technology
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    • v.10 no.1
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    • pp.1-12
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    • 1978
  • Concanavalin-A, lectin extracted from Korean native plant “Banha”(Pine-llia Termata) and their conjugation products with tyrosine and 5-iodo-6-aminouracil were labelled by radioactive iodiae-125, and these labelled compounds were subjected to a hemagglutination test in vitro. The labelling procedures were presented with respect to labelling yield and the trends on the conjugation reaction of lectin with various amino acids were discussed. The preliminary results on the hemagglutination tests against cancer tissues were presented and the potential clinical applications of these labelled compounds were discussed.

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Effects of Gibberellin and Atonic Acid on Growth and Fiber Yield of Ramie Plant (식물생장조절자의 처리가 모시풀의 생육 및 섬유수량에 미치는 영향)

  • 정동희;김상곤;권병선;황종진
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.38 no.3
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    • pp.213-218
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    • 1993
  • An experiment was carried out to investigate the effects of plant growth regulators on the growth and fiber yield of ramie. Gibberellin (GA) and Atonic acid were applied at the various levels of application dates, application frequencies and concentration. Stem growth of ramie increased greatly by applying GA on the meristem of shoot apex. Among three treatments of application frequencies of GA, that is, one time application at the stage of stem length with 50cm, twice applications at the stem length of 50cm and 100cm, and three times applications at stem length of 50cm, 100cm and 150cm, stem growth increased more as application frequency increased. GA application is more effective on stem growth at the later stage of growth than the earlier growth stage. GA treatment of 100 to 300 ppm is more effective on stem elongation than 50 ppm, which was due on the elongation of internodes without increase in number of nodes. One time application of GA enhanced leaf growth more or less regardless of concentration, but GA was applied more frequently, leaf growth was inhibited more at higher concentration. Fiber yield was the highest at the treatment of three times application of GA with 100 ppm. This treatment also showed the highest percentage of fiber with 5.3%, which is much higher value compared with that of control treatment with 4.6%. Atonic acid was less effective on stem elongation than GA, but it also seemed to be effective on the enhancement of fiber development.

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Studies on the Trial Cultivation of Italian Liquorice -A Breeding Method and Glycyrrhizin Content- (이태리종 감초의 재배에 관한 연구)

  • Park, Chae-Joo;Kim, Chong-Won
    • Korean Journal of Pharmacognosy
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    • v.1 no.1
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    • pp.33-34
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    • 1970
  • The cultivation of Italian liquorice root was carried out and the three-year-old roots of average wet weight 800g were harvested. In early April the cut root was transplanted and the rate of survival was $50{\sim}60%$. The treatment of it with dilute Atonic solution increased the rate to 96%. The glycyrrhizin content in the root was: five-year-old root 7%, four-year-old 7.5%, three-year-old 6.7%, and two-year-old 4.7%.

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Cauda Equina Syndrome Following Intrathecal Hypertonic Saline Administration (자주막하강내 고장성 생리식염수 투여후 발생한 마비증후군)

  • Choe, Huhn
    • The Korean Journal of Pain
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    • v.3 no.1
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    • pp.55-58
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    • 1990
  • A case of severe complications following intrathecal administration of 45 ml of hypertonic saline solution for the treatment of postherpetic neuralgia was presented. Transient immediate complications included were tachycardia, hypertension, neck stiffness and muscle twitch. Pulmonary edema, paralytic intestinal obstruction, and the cauda equina syndrome including sphincter disorder with atonic urinary bladder developed shortly after the injection. Tenesmus and sensory abnormality around perineum and soles were the longlasting complications.

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Changes of Chemical Properties in Processing of Low Salted and Fermented Shrimp Using Gamma Irradiation immediately before Optimum Fermentation (저염 새우젓 제조를 위한 최적 숙성직전의 감마선 조사시 화학적 품질변화)

  • Lee, Kyong-Haeng;Ahn, Hyun-Joo;Lee, Cherl-Ho;Kim, Yeung-Ji;Byun, Myung-Woo
    • Korean Journal of Food Science and Technology
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    • v.32 no.5
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    • pp.1051-1057
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    • 2000
  • Gamma irradiation was applied to develop fermented shrimp product with lower salt concentration, high sensory quality and storage stability. Shrimp was prepared with 15 and 20% of salt and fermented at $15^{\circ}C$. The sample was irradiated for 15% added salt at the 4th week and for 20% at the 6th week during fermentation with 0, 5 and 10 kGy absorbed doses. The irradiation was applied at optimum stage of fermentation determined when the content of amino nitrogen(AN) arrived approximately 400 mg%. Chemical properties such as amino nitrogen(AN), volatile base nitrogen(VBN), trimethylamine(TMA) and neutral protease activity were examined during whole fermentation. The AN, VBN, TMA and protease activity were not affected immediately after gamma irradiation. The more NaCl concentrations and irradiation dose, the less content of chemical compounds and protease activity was found. From the results of chemical properties, it was concluded that fermented shrimp with 15% of salt and irradiated at 10 kGy before optimum fermentation, or 20% and 5 kGy or above were maintained the sound quality during storage compared with the control.

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Continuous Distal Ileostomy Drip Feeding with the Secretion of the Proximal Stoma in a Neonate with IIIa Ileal Atresia (IIIa 회장 폐쇄증 환자에서 원위부 회장루를 통한 근위부 공장루 분비물의 지속적 점적 영양 관리 1례)

  • Yang, Eun Seok;Choi, Yun Chang;Kim, Eun Young;Moon, Kyung Rye;Chang, Jeong Hwan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.7 no.2
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    • pp.260-263
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    • 2004
  • Short-bowel syndrome is functionally defined as a state of malabsorption following loss of small bowel, which comprises the sequelae of nutrient, fluid, and weight loss. The proximal segment of the bowel of a patient with intestinal atresia is usually grossly distended and atonic. In contrast, distal segment is smaller. For this reason, anastomosis of the proximal and the distal segment is technically difficult and may cause no propulsion even when they are anastomosed. We experienced that continuous drip ileostomy feeding with the secretions from the proximal stoma stimulated the distal bowel to accommodate and resolved many sequelae following loss of small bowel in a patient with short-bowel syndrome due to IIIa ileal atresia.

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