• Title/Summary/Keyword: AtT20

Search Result 5,566, Processing Time 0.036 seconds

A Study on Deformation Behaviors of Al 6061, 7075 Tube at Different Heat Treatments for Warm Hydroforming (온간액압성형공정 적용을 위한 알루미늄 6061, 7075 튜브의 열처리조건에 따른 변형특성연구)

  • Yi, Hyae-Kyung;Moon, Young Hoon
    • Journal of the Korean Society for Heat Treatment
    • /
    • v.20 no.1
    • /
    • pp.1-10
    • /
    • 2007
  • The deformation behaviors of full annealed and T6 treated 6061, 7075 aluminum tubes are investigated at various temperature performing uniaxial tensile test. Full annealed Al 6061 and Al7075 tubes, and T6 treated Al7075 tube don't show sharp local necking with an elongation of 50% at $300^{\circ}C$. So it is expected that influenced by elevated tempterature. At $300^{\circ}C$ and strain rate of 0.001/s, many micro-cracks are observed in T6 treated Al 6061 tube, which is believed to be responsible for the decrease of total elongation.

T Cells Development Is Different between Thymus from Normal and Intrauterine Growth Restricted Pig Fetus at Different Gestational Stage

  • Lin, Yan;Wang, Junjun;Wang, Xiaoqiu;Wu, Weizong;Lai, Changhua
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.26 no.3
    • /
    • pp.343-348
    • /
    • 2013
  • This experiment was conducted to evaluate the development of T cells in intrauterine growth retarded (IUGR) piglets at different gestational stages, and tentatively explore the relationship between T cells development and the Notch signaling pathway. A total of 18 crossbred (Landrace${\times}$Large white) primiparous sows were mated at similar weights and estruses and euthanized at d 60, 90 and 110 of gestation with six replicates for each time point. One IUGR and one normal fetus were picked from each litter. The T-cell subsets, mRNA expression of Delta-like1, Delta-like4, Jagged1, and Notch2 genes in the thymus were investigated. Compared to normal piglets, $CD3^+CD4^-CD8^+$ cells in IUGR fetuses at d 90 was 0.13% lower (p<0.05). At d 110 of gestation $CD8^+$ T cells in IUGR fetuses was 0.19% lower (p<0.05). The percentage of $CD8^+$ T cells was 3.14% lower (p<0.05) of the total T cells in IUGR pigs at d 60. The abundance of Notch2 and Delta-like4 mRNA at d 110 was 20.93% higher and 0.77% (p<0.05) lower, and Delta-like1 mRNA at d 90 was 0.19% (p<0.05) higher compared to normal pigs. These results suggested that normal fetuses had a greater proportion of T-cell subsets at earlier gestation periods, and the Notch signaling pathway was likely partially responsible for these differences to some degree.

GENERALIZED CONDITIONAL INTEGRAL TRANSFORMS, CONDITIONAL CONVOLUTIONS AND FIRST VARIATIONS

  • Kim, Bong Jin;Kim, Byoung Soo
    • Korean Journal of Mathematics
    • /
    • v.20 no.1
    • /
    • pp.1-18
    • /
    • 2012
  • We study various relationships that exist among generalized conditional integral transform, generalized conditional convolution and generalized first variation for a class of functionals defined on K[0, T], the space of complex-valued continuous functions on [0, T] which vanish at zero.

Construction of Differential Type Search Coil Magnetometer (차동형 탐지코일 마그네토미터 제작)

  • Kim, J.H.;Son, De-Rac
    • Journal of the Korean Magnetics Society
    • /
    • v.20 no.5
    • /
    • pp.178-181
    • /
    • 2010
  • Search coil magnetometer has been used for detection of ac magnetic field with high sensitivity. To reduce demagnetizing factor of core and increase S/N ratio of search coil magnetometer, the core was divided by two parts and coil was wound on each cores. Two coils were connected serially and put into amplifier as differential mode. Constructed 120 mm length search coil magnetometer shows linearity of 0.03%, sensitivity of 9.3 mV/nT, and resolution of 20 pT at 1 Hz.

Changes in the Physicochemical Characteristics and Trans Acid of Cottonseed Oil during Selective Hydrogenation (선택적 수소첨가 면실유의 이화학적 특성변화 및 트란스산 생성)

  • Kim, Hyean-Wee;Kim, Jong-Soo;Shim, Joong-Hwan;Park, Seong-Joon;Ahn, Tae-Hoe;Park, Ki-Moon;Choi, Chun-Un
    • Korean Journal of Food Science and Technology
    • /
    • v.22 no.6
    • /
    • pp.681-685
    • /
    • 1990
  • Changes in the physicochemical characteristics and trans acid of cottonseed oil under the condition of selective hydrogenation, temperature$210^{\circ}C,\;H_2\;pressure\;0.3\;kg/cm^2$ Ni catalyst amount 0.12% (in oil), agitation speed 280 rpm, were investigated. The saturated fatty acid such as palmitic acid and stearic acid did not show any difference, while linoleic acid($50.03%{\rightarrow}9.38%$) were transformed to oleic acid ($20.65%{\rightarrow}60.35%$) during hydrogenation. In linoleic acid isomers, cc form were reduced significantly, but ct, tc, tt form showed little change, respectively. In oleic acid isomer, t form increased markedly, whereas there was no significant difference in c form. Meanwhile, melting point(MP) and solid fat content (SFC) were linearly increased, but iodine value(IV) linearly decreased as hydrogenation proceeded. From these results, linear regression equations were obtained as follows. MP & IV : Y= 1.59-2.36X(r=-0.96, p<0.05), SFC($at\;20^{\circ}C$) & MP : Y=2.81+2.01X(r=0.96, p<0.05), SFC($at\;20^{\circ}C$) & IV : Y=9.40-5.16X(r=-0.99, p<0.01), SFC($at\;20^{\circ}C$) & 18 : 1t : Y=6.25+8.48X(r=0.97, p<0.05)

  • PDF

Tanshinone I, an Active Ingredient of Salvia miltiorrhiza, Inhibits Differentiation of 3T3-L1 Preadipocytes and Lipid Accumulation in Zebrafish

  • Kwon, Hyo-Shin;Jang, Byeong-Churl
    • Journal of Korean Medicine for Obesity Research
    • /
    • v.20 no.2
    • /
    • pp.109-121
    • /
    • 2020
  • Objectives: Tanshinone I is a bioactive constituent in Salvia miltiorrhiza. At present, the anti-obesity effect and mechanism of tanshinone I are not fully understood. Here we investigated the effect of tanshinone I on lipid accumulation in 3T3-L1 preadipocytes and zebrafish. Methods: Lipid accumulation and triglyceride (TG) content in 3T3-L1 cells were determined by Oil Red O staining and AdipoRed assay, respectively. The expression and phosphorylation levels of adipogenic/lipogenic proteins in 3T3-L1 cells were evaluated by Western blotting. The messenger RNA (mRNA) expression levels of adipogenic/lipogenic markers and leptin in 3T3-L1 cells were measured by reverse transcription polymerase chain reaction (RT-PCR). Lipid accumulation in zebrafish was assessed by LipidGreen2 staining. Results: Tanshinone I at 5 μM largely blocked lipid accumulation and reduced TG content in differentiating 3T3-L1 cells. Furthermore, tanshinone I decreased the expression of CCAAT/enhancer-binding protein-α (C/EBP-α), peroxisome proliferator-activated receptor-γ (PPAR-γ), fatty acid synthase (FAS), acetyl CoA carboxylase (ACC), and perilipin A but also the phosphorylation of signal transducer and activator of transcription-3 (STAT-3) in differentiating 3T3-L1 cells. In addition, tanshinone I increased the phosphorylation of adenosine 3',5'-cyclic monophosphate (cAMP)-activated protein kinase (AMPK) while decreased the intracellular adenosine triphosphate (ATP) content with no change in the phosphorylation and expression of liver kinase-B1 in differentiating 3T3-L1 cells. Importantly, tanshinone I also reduced the extent of lipid deposit formation in developing zebrafish. Conclusions: These findings demonstrate that tanshinone I has strong anti-adipogenic effects on 3T3-L1 cells and reduces adiposity in zebrafish, and these anti-adipogenic effect in 3T3-L1 cells are mediated through control of C/EBP-α, PPAR-γ, STAT-3, FAS, ACC, perilipin A, and AMPK.

Effects of Urea and K2SO4 treatment on the mineral nutrient concentration and fruit skin color of 'Mibaekdo' peach fruits at harvest (Urea와 K2SO4 처리에 의한 복숭아 '미백도'에서 수확 시 과실의 무기성분 농도 및 과피색 변화)

  • Moon, B.W.;Yoon, I.K.;Moon, Y.J.;Nam, K.W.;Lee, Y.C.
    • Journal of Practical Agriculture & Fisheries Research
    • /
    • v.15 no.1
    • /
    • pp.95-105
    • /
    • 2013
  • This study has been conducted to investigate the effect of Urea and K2SO4 treatment at stone hardening stage and 20 days before harvest on soil chemical properties, mineral nutrient concentration and quality of 'Mibaekdo' fruit peach. K concentration after Urea and K2SO4 treatment in soil was increased significantly by Urea 162g+K2SO4 188g/tree(standard amount) treatment at stone hardening stage, K2SO4 1.0% tree-spray, Urea 81g+K2SO4 94g/tree(half amount), Urea 162g+K2SO4 188g/tree and Urea 324g+K2SO4 376g/tree(double amount) soil treatment before harvest 20 days compared to control. T-N, K and Ca concentration in leaf was increased significantly by all treatment. but Na concentration in leaf was increased by Urea 0.5% and K2SO4 1.0% tree-spray treatment before harvest 20 days. T-N concentration in fruit skin was increased significantly by standard amount soil treatment, which decreased by K2SO4 1.0% tree-spray and half amount soil treatment. T-N, K and Ca concentration in fruit flesh(1~10mm depth flesh from peel) were increased markedly by all treatment excepted Urea 0.5% tree-spray. The leaf weight at harvest was increased markedly by Urea 0.5% tree-spray, standard amount and double amount treatment before harvest 20 days. Fruit weight was increased significantly by standard amount compared to all treatment. Red fruit skin(Hunter a value) progress was effective by K2SO4 tree-spray, half amount and double amount treatment before harvest 20 days. Fruit SSC was increased significantly by Urea 0.5% and K2SO4 tree-spray before harvest 20 days, standard amount treatment at stone hardening stage compared to control.

The Effects of Combination of PDGF-BB and Dexamethasone on Differentiation of MC3T3-E1 Cells (MC3T3-E1 세포의 분화에 PDGF-BB와 Dexamethasone 병용 효과)

  • Lee, Jae-Mok;Seh, Jo-Young;Kim, Sung-Jo;Choi, Jeom-Il
    • Journal of Periodontal and Implant Science
    • /
    • v.30 no.1
    • /
    • pp.27-39
    • /
    • 2000
  • To evaluate the effects of Dexamethasone(Dex), Platelet derived growth factor-BB(PDGF) and combination of Dex and PDGF(DP) on the growth and differentiation of MC3T3-E1 cells, Dex($10^{-7}\;M$) and PDGF(10 ng/ml) in experimental group were added to the cells at the days 5, 10, 15, 20, 25 and examined for cell proliferation activities, DNA synthesis activities, ALP activities and bone nodule formation. The results were as follows : 1. In Dex group, cell proliferation, DNA synthesis and ALP activities were lower until 15 days when compared to the control group. Bone nodules formation were shown at 10 days. 2. In PDGF group, cell proliferation and DNA synthesis activities were higher until 15 days and ALP activities were lower when compared to the control and Dex groups. Bone nodules formation were shown at 20 days. 3. In DP group, cell proliferation and DNA synthesis activities of PDGF were suppressed by Dex and synergistic effects of combination of Dex and PDGF on ALP activities were shown at days 5 when compared to control and Dex groups. Bone nodules formation activities of Dex were suppressed by PDGF.

  • PDF

Effect of Feed Allowance on Selection, Intake and Nutrient Utilization of Green Maize (Zea mays) by Goats

  • Dutta, N.;Sharma, K.;Hasan, Q.Z.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.13 no.4
    • /
    • pp.483-486
    • /
    • 2000
  • The influence of feed allowance on intake and nutrient utilization by Barbari goats given green maize (Zea mays) and potential feeding value of left-overs were studied. The goats were offered food at 3 levels to give left-overs of about 20% (T-1), 35% (T-2) and 50% (T-3) DM of offered amount. A marked effect of refusal rate on intake and digestibility of nutrients was found. The DMI, g/kg $W^{0.75}$ increased from 39.86 in T-1 to 50.91 and 66.55 g in groups T-2 and T-3, respectively. Allowing selective consumption at higher levels (T-2 and T-3), the intake of TDN and DCP from green maize was found not only to meet the maintenance requirement but provided surplus energy and protein for substantial production. The variability in diet selectivity between goats under different treatments was pronounced. As the level of food excess increased to T-3, the left overs had a higher IVDMD and crude protein and decreased cell wall constituents (p<0.05). Considering the substantial increase in intake and digestibility from feeding green maize at high allowances to goats, further studies are needed to develop practical feeding strategies.

Preservation of Acid Treated Bivoltine Eggs in Silkworm Bombyx mori L.

  • Rajanna, K. L.;Raju, P.Jayarama;Prabhakar, C.J.;Kamble, C.K.
    • International Journal of Industrial Entomology and Biomaterials
    • /
    • v.17 no.2
    • /
    • pp.165-168
    • /
    • 2008
  • The hybrid ($CSR2{\times}CSR4$) eggs treated with acid were taken up for the study with an objective to develop long-term preservation schedule. The hybrid eggs obtained with two mating duration (3 h and 6 h) and oviposition period (6 h and 24 h) with two age groups of eggs (24 h and 36 h) were treated with Hydrochloric acid. These eggs were subjected to preservation at $5^{\circ}C$ in single step refrigeration and at $5^{\circ}C$ and $2.5^{\circ}C$ under double step refrigeration from $10{\sim}120$ days. These eggs were released from the cold storage as per the specified durations and incubated at standard conditions and allowed 2 h for hatching at 450 lux light. Hatchability was found to be significantly higher or on par with the control in three treatments (T1, T2 and T4) where the eggs are preserved continuously at $5^{\circ}C$ up to 30 days. However under double step refrigeration, hatching was not significantly affected in 20+60 day's combination of T1 treatment up to 80 days. Bioassay studies of the promising treatment i.e.. T1 with (20+60) days indicated that early stage loss and cocoon yield was found to be on par with the control. Hence this treatment was recommended for preservation of acid treated new bivoltine hybrid layings. Details of the hatchability and rearing performance of long term preservation of acid treated eggs are discussed.