• Bulletin of the Korean Chemical Society
• /
• 제26권5호
• /
• pp.717-718
• /
• 2005

• 대한화학회지
• /
• 제59권3호
• /
• pp.205-208
• /
• 2015

• 대한약학회:학술대회논문집
• /
• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
• /
• pp.362.2-362.2
• /
• 2002

Antofine belongs to the Phenathroindolizidine group of alkaloids. This natural products exhibit interesting biological properties such as antitumour activity. and anti-inflammentory. Wittig reaction of phenathrenealdehyde with the phosponium salt provided the phenathreneazidealkene in good yield. Intramolecular 1.3-dipolar cycloaddition of the resulting azidealkent in refluxing benzene proceeded the imine. It was reduced with cyanoborohydride of Noyori's Asymmetric Hydrogenation. (omitted)

• Bulletin of the Korean Chemical Society
• /
• 제31권3호
• /
• pp.694-696
• /
• 2010