• The Journal of Dong Guk Oriental Medicine
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• v.7 no.2
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• pp.9-25
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• 1999

The results of the pathogenesis analysis of a diarrhea of the differential diagnosis s uggested in Sanghaulun and Dongyishoushibaoyuan are as followings. 1. The various factors such as cold, asthenia and sthenia are the pathogenesis of a diarrhea. Among of them, the asthenia-cold is the main pathogenesis, and theis sho ws that the above pathogenesis could belong under the constitutional pathogenesis of Shaoyinren. 2. Dong-Mu proved that all the symptoms of Sanyinbing were the symptom of Shao yinern. The case of Shanyinbing involved by the heat-evil, however, indicates that I t is not the pathogenesis of Shaoyangren. 3. To understand the various differential diagnosis of the pathogenesis in Sanghanlu n. the study on the theoretical relation with the constitutional pathogenesis in Dong yishibaoyuan will be necessary.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.9 no.1
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• pp.75-87
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• 2003

Recently, the occurrence and death rates of cancer have increased rapidly. Metastasis and recurrence is the most important factor of death from cancer. So inhibition of recurrence and metastasis can increase the cure rate of cancer disease. At the basic chinese traditional medicine(TCM), there are a lot of theory related to neoplasm treatment. The metastasis and recurrence of neoplasm was the basis of yudu(餘毒) on remained neoplasm cell and stagnation of blood, thermotoxo, phlegm, asthenia of healthy enerngy and stagnation of vital energy. The principles therapy of neoplasm on metastasis and recurrence was based on knowledge of the method of support the healthy energy and strengthen the body resistance, promote blood circulation to remove blood stasis, clear away heat and toxic materials, dissipate phlegm and disperse the accumulation of evils. But the major clinical features of neoplasm was to be considered in developing a treatment plan include (1) distinguish between clinical and pathologic staging - acute and chronic, (2) classification of pathologic pattern, and (3) distingction of body situation : for examples asthenia - sthenia etc. It was most important to distinguish between supporting the healthy and eliminating the evil factors and to treat differently at the root and the branch cause of a neoplasm. This paper's results indicate that identification and effective use of THM can inhibite netastasis and recurrence and then it will help increasing survival rate. Also as BioTechnology(BT) has developed rapidly nowadays, as genes related to cancer have revealed. So it will give rise to the development of searching the mechanism of herb medicines which have inhibition effects of metastasis and recurrence.

• Journal of Korean Medical classics
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• v.20 no.4
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• pp.45-63
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• 2007

In this dissertation, I will focus on the channel entry, the effect and the treatment throughout books of oriental medicine from ancient to modern in order to classify the medicines of the Spleen as main or supplementary organ. The results are as follows: 1. The medicines which work on the Spleen(本臟) chiefly were 38, which were Gingseng Radix(人蔘), Astragali Radix, Hoelen, Atractylodis Rhizoma alba(白朮), Glycyrrhizae Radix(甘草), Atractyodis Rhizoma(蒼朮), Aurantii Nobilis Pericarpium(陳皮), Pinelliae Rhizoma(半夏), Nelumbinis Semen(蓮肉), Semen Euryacles, Crataegi Fructus, Dolichoris Semen(扁豆), Hordei Fructus Germinatus(麥芽), Dioscoreae Radix(山藥), Paeoniae Radix(白芍藥), Zingiberis Rhizoma(乾薑), Arecae Pericarpium(大腹皮), Cimicifugae Rhizoma(升麻), Aurantii Fructus(枳殼), Tiglii Semen(巴豆), Scirpi Rhizoma(三稜), Paeoniae Radix rubra(赤芍藥), Amydae Carapax(鱉甲), (Coptidis Rhizoma(黃連), Dioscoreae Radix(萎藥), Amomi Semen(砂仁), Zingiberis Rhizoma(生薑), Saussureae Radix(木香), Cinnamomi Cortex Spissus(肉桂), Myristicae Semen, Alpiniae Fructus(益智仁), Evodiae Fructus(吳萸), Caryophylli Flos(丁香), Agastachis Herba(藿香), Fructus Piperis Nigri Seu Albi(胡椒), Acontii Tuber(附子), Alpiniae Officinari Rhizoma(良薑), Fructus Galangae. 2. The medicines which work on the other viscera(他臟) chiefly were 12, which were Talcum(滑石), Bupleuri Radix(柴胡), Semen Lepidii Seu Descurainiae, Mori Cotex Radicis(桑白皮), Aurantii lmmaturi Pericarpium(靑皮), Gardeniae Fructus(梔子), Forsythiae Frucus(連翹), Antelopis cornu(羚羊角), Alimatis Rhizoma(澤瀉), Epimedii Herba(仙靈脾), Cyperi Rhizoma(香附子), Rhizome Chuanxiong(川芎). 3. medicines, effected on the Spleen functioned through any other viscera were as follows: Talcum(滑石) works to treat renal heat Entering the Spleen(腎熱入脾) Bupleuri Radix(柴胡) works to treat Hepatic Asthenia Entering the Spleen(肝虛入脾) Semen Lepidii Seu Descurainiae and Mori Cotex Radicis(桑白皮) works to treat Pulmonary gi Entering the Spleen(肺氣入脾) Aurantii lmmaturi Pericarpium(靑皮) works to treat Hepatic gi Entering the Spleen(肝氣入脾) Gardeniae Fructus(梔子) and Forsythiae Frucus(連翹) works to treat Cardiac Heat Entering the Spleen(心熱入脾) Antelopis cornu(羚羊角) works to treat Hepatic wind Entering the Spleen(肝風人脾) Alimatis Rhizoma(澤瀉) works to treat Hepatic heat Entering the Spleen(肝熱入脾) Epimedii Herba(仙靈脾) works to treat Renal asthenia Entering the Spleen(腎虛入脾) Cyperi Rhizoma(香附子) 와 Rhizome Chuanxiong(川芎) works to treat Hepatic gi Entering the Spleen(肝氣入脾) In the study of concerning the medicines effected on the spleen, It is considered that it dedicated to development of the medicines related to the spleen and making efficient use of the medicines.

• The Journal of Dong Guk Oriental Medicine
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• v.3
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• pp.237-267
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• 1994

The purpose of this study is the approach to I.I.C.P. centered on the meaning of consciousness disorder and the pathological aspect of Kwul (Jose consciousness ; faint, fall into a coma). The meaning of consciousness disorder and apoplexy is evidently involved the definition of Kwul. 1. It is found that the etymological interpretation on Kwul which the energy rises back to go through blocked space and the meaning interpretation of regarding Kwul as apoplexy with medical viewpoint, are related with consciousness disorder and motor disturbance in IICP in the aspect of the rise of Kwul and the abnormal rising of vital energy and blood, In addtion, the overall of meaning of Kwul is showed in table <1-1> by reference to doctors of many generations, 2. The pathology of Kwul includes abnormal rising, sthenia-syndrome in the upper part and asthenia in the lower, the origin of Kwul, the lower, looking like Yin by too sthenic Yang and looking like Yang by too sthenic Yin. The headache, vomiting, papilledema, paralysis of nervi craniales, coma, blood pressure rising, tachycardia by I.I.C.P can be regarded as a conception of trouble of vital energy, sthenia-syndrome of Kwul. The pulse pressure, brachycardia, bradypnea can be regarded as the conception of looking like Yin by too sthenic Yang. 3. In the emergency of Kwul, the abnormal ternimal reversion of the Kwulyin channel, Kuyang channel, and three Yins are related with the phenomenon in I.I.C.P. It is considered that the reverse movement of materials, I.I.C.P. can be closely observed by giving meaning on the meridian of Kwul in Somunkwulron. And the content of phrases of Naelyung which includes consciousness disorder refered in the chapter of Kwul, is compared with I.I.C.P. 4. The followings should be considered; examination of optic symptom and abnormal posture in cerebral herniation ; understanding and working out counterplans of factors and symptoms of consciousness disorder by the observation of vital sign, check of general stages, neurologic inverstigation, clinical diagnosis, and subsidiary diagnosis; application of morphological change of opinion; addtion of the conception of demonstration centered on Yunkyung, Samyinkwulruk, asthenia and thenia of healthy energy in oriental medicine. 5. The similarity of Kwul and I.I.C.P. can be found from etiology and pathotenic factor. The similarity is clearly found by investigation of etiology, pathotenic factor, symptoms and thrapy of Kwul, disease symptom ar.d other symptoms.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.857-866
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• 2002

The main current in the pathology of oriental medicine is composed of etiologic factor, pathogenesis and clinical manifestation. The access of a disease is consist of etiologic factor, location of the lesion, nature of the disease and patient's condition. The nature of disease and the property of a drug are inseparably related to each other. The nature of disease is composed of six exogenous factors, cold and heat, deficiendy and excess, Yinyang and pain. Cold nature is divided into cold symptom due to excess and asthenia cold, fever nature is divided into sthenic fever and asthenic fever. According to the location, cold and heat can be subdivided into heat in the upper and cold in the lower, cold in the upper and heat in the lower, exterior cold and interior heat, exterior heat and interior cold. Yin syndrome characterized by hypofunction of the viscera is generated from insufficiency of yang-qi, excess of yin-coldness, deficiency of both qi and the blood.

• Journal of Pharmacopuncture
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• v.9 no.1
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• pp.59-67
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• 2006

Objectives : This study planed to evaluate effect of oriental medicine therapy treatment method of dyspnea that happen from cancer of the pancreas patient who accompany Multiple metasis Methods : Patient complained dyspnoea during admission into dept. Of internal medicine, college of oriental medicine, Dong-eui Univ, was appealed patient treated by Oriental medicine therapy that is of use Herb Medication and Herbal -acupuncture Treatment being diagnosed in lung asthenia including deficiency of Eum and insufficiency of Gi of the lung(肺虛), the fire due to deficiency(虛火), and loving warfare of symptoms evaluated through VAS (visual analog scales). Results & Conclusion : Patient's difficulty in breathing symptoms took a favorable turn after treatment. This study means that Oriental medicine therapy that is difficulty in breathing symptoms that happen from patient surely has effectiveness.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.59-66
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• 2008

We referred to twenty-two Korean medicinal literatures for application of a single-medicine prescription using Asparagi Tuber(Asparagus cochinchinensis) to form the groundwork for scientific modernization of Korean medicine. Our study revealed the following. 1. Principle expectant effects of Asparagi Tuber were prolong life; elevation of stamina or activity; improvement of asthenia; remedy of epilepsy, mental disease or convulsions; relief of xerosis; treatment of tumor, abscess or intumescence; extermination of endoparasite; solution of numbness, etc. 2. The records show that 95% of directions are per oral. 3. 38% of the cases, Asparagi Tuber was used without its jacket or core. 4. Alcohol and honey were generally used as solvent and additive. We suggest to perform the further studies for the scientific verification of the expectant effects of Asparagi Tuber and its different efficacy by processing, solvent and additives.

• The Journal of Internal Korean Medicine
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• v.28 no.4
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• pp.791-796
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• 2007

Objective : This study was conducted to find the relationship between syndrome-differentiation and Sasang-constitution in chronic fatigue patients. Methods : The subjects were 72 adults with chronic fatigue who visited Dunsan Oriental Hospital of Daejeon University between March 2007 and April 2007. Their main complaint was fatigue for longer than 6 months and they did not have any physical or mental problems. We measured their fatigue degree by using Chalder fatigue scale and health habits. To evaluate relationship between syndrome-differentiation with sasang-constitution, The patients were divided into four syndrome-differentiations, such as liver and kidney asthenia of Yin, spleen and kidney deficiency of Yang, deficiency of lung and spleen qi, and deficiency of heart and spleen blood. We also diagnosed Sasang-constitution by using Questionnaire for Sasang Constitution Classification II (QSCCII). Results : Among the 72 patients, 41.4%, 34.5% and 24.1% of belonged in Soyangin, Soeumin and Taeumin respectively. Interestingly, we found a meaningful correlation between syndrome-differentiation and physiological function by Sasang-constitution. Conclusion : The result may help Oriental medicine understanding and treatment of chronic fatigue-related diseases and patients.

• Clinical and Experimental Pediatrics
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• v.59 no.11
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• pp.456-459
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• 2016

Triple-A syndrome, also known as Allgrove syndrome, is a rare autosomal recessive disorder. The 3 features of this syndrome are achalasia, adrenal insufficiency, and alacrima. Achalasia could be the first manifestation of the triple-A syndrome; however, its etiology is unclear. Alacrima is generally asymptomatic but can be detected by obtaining patient history. Although adrenal insufficiency could have manifestations such as asthenia, it might be wrongly diagnosed as muscle fatigue. Vitamin D and calcium supplements are usually prescribed for the prevention of osteoporosis. Neurologic manifestations could be present in adults. In some individuals with this disorder, genetic examination indicates mutations in both alleles of the AAAS gene, which encodes a special 546-amino-acid protein designated ALADIN, and in chromosome 12q13. The genetic cause of the triple A syndrome in some patients who do not have an identified mutation is unknown. While very few such cases have been reported till date, one such case was presented to us as an edentulous child.

• Journal of Korean Medical classics
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• v.23 no.1
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• pp.91-100
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• 2010

In this study, I investigated physiology and pathology of the kidney and then researched deficiency of the kidney-nourishing the Eum music therapy to apply for clinical use, because symptoms such as chronic fatigue, morbus asthenia, anxiety, dizziness, tinnitus, and amnesia are prevalent in our modern societies. These symptoms are due to deficiency of the kidney. The kidney stores vital essence and has a function to keep activities as motive power. If the kidney is abnormal in storing the essence and holding Gi, various symptoms like dizziness, tinnitus, amnesia are caused by deficiency of the kidney. In deficiency of the kidney-nourishing the Eum music therapy, Water-Gi music which can store the essence is mainly used. In case of patients with deficiency of the kidney, dizziness, tinnitus, and amnesia, we can make use of NO.3, BWV 1068, Air of J.S.Bach and Jinyangjo of Geomungo. If there are flaring-up and fidgetiness due to deficiency of vital essence, Earth-Gi music that can help the vigor of spleen and stomach should be used prior to Water-Gi music. In the concrete, Hahyeondodeuri of Yeongsanhoesang played on Geomungo can be used. The tinnitus is caused by wind-heat and fire in the gallbladder. It is good to nourish the Eum through Water-Gi music after dispelling pathogens through Jajinmori among Gayageum sanjo.