• Journal of Preventive Medicine and Public Health
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• v.32 no.1
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• pp.17-29
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• 1999

Objectives. This study was carried out to analyze the hearingthreshold levels and relating factors of 1,048 workers with noiseinduced hearing loss$(D_1)$. Methods. We analyzed the hearing-threshold levels and relating factors of 1,048 workers with noise-induced hearing loss$(D_1)$ examined by the summary reports of specific health examination results of industries and personal reports of specific health examination results reported by 58 specific health examination institutes and 8 secondary pneumoconiosis examination institutes in 1996. Results. Among 1,048 workers at 510 workplaces, male workers were 1,009 (96.3%) and female workers were 39 (3.7%). The mean ages of workers initially exposed to noise and at present were 28.7 and 47.2, respectively. The duration of total exposure was 16.5 years. Average hearing-threshold levels analyzed by three-divided classification of the study subjects were 43.7dB(Lt) and 42.6dB(Rt). Those analyzed by six-divided classification were 50.5dB(Lt) and 48.6d8(Rt). Among workers with noise-induced shearing loss$(D_1)$, 16.3% was unilateral hearing loss and 84.6% was classified to compensation case. 8.8%(Rt) and 10.2%(Lt) of them were suspected to be conductive hearing loss by differences of air-bone hearing-threshold levels. Hearing-threshold levels of workers in manufacturing industry were significantly increased during the short exposure compared with the levels in mining industry. Among manufacturing industries, hearing-threshold levels of workers in trailer and other transportation equipment manufacturing industry were significantly increased. Age and duration of total noise exposure were not significantly related to the average hearing-threshold levels analyzed by three-divided classification. Hearing-threshold levels of female workers were significantly increased during the short exposure compared with those of male workers. Hearing-threshold levels of workers at the high risk group, ages of 20s, 30s and total exposure duration of less than 10 years, were not significantly increased compared with those of the other groups. However, they were exposed at young ages. The 3 leading industries of workers at high risk group were trailer and other transportation equipment manufacturing, automobile manufacturing and assemble-metal manufacturing industries. Conclusions. This study was the first nationwide analysis of the hearing-threshold levels and relating factors of workers with noise. induced hearing loss$(D_1)$. We found the differences of the real number by the statistics of the department of labour and the expected number of worker' s compensations for occupationally-induced hearing loss estimated by this study. According to the results of this study, we should carefully examine the methods to narrow this difference.

• Journal of Life Science
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• v.16 no.3 s.76
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• pp.409-414
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• 2006

Molecular chaperones and folding enzymes in the endoplasmic reticulum (ER) associate with the newly synthesized proteins to prevent their aggregation and help them fold and assemble correctly. Chaperone function of BiP, which is a Hsp70 homologue in ER, is controlled by the N-terminal ATPase domain. The ATPase activity of the ATPase domain is affected by regulatory factors. BAP was identified as a nucleotide exchange factor of BiP (Grp78), which exchanges ADP with ATP in the ATPase domain of BiP This study presents whether BAP can influence folding of a protein, immunoglobulin heavy chain that is bound to BiP tightly. We first examined which nucleotide of ADP and ATP affects on BAP binding to BiP The data showed that endogenous BAP of HEK293 cells prefers ADP for binding to BiP in vitro, suggesting that BAP first releases ADP from the ATPase domain in order to exchange with ATP. Immunoglobulin heavy chain, an unfolded protein substrate, was released from BiP in the presence of BAP but not in the presence of ERdj3, which is another regulatory factor for BiP accelerating the rate of ATP hydrolysis of BiP The ADP-releasing function of BAP was, therefore, believed to be responsible for immunoglobulin heavy chain release from BiP. Grp170, another Hsp70 homologue in ER, did not co-precipited with BAP from $[^{35}S]$-metabolic labeled HEK293 lysate containing both overexpressed Grp170 and BAP. These data suggested that BAP has no specificity to Grp170 although the ATPase domains of Grp170 and BiP are homologous each other.

• Korean Journal of Social Welfare
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• v.62 no.2
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• pp.279-306
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• 2010

This study is to compare and analyze the policy decision process between Korea Long-term Care Insurance and Japan's using policy network theory as an analysis tool, and to lead political and theoretical implications. The result of the study is summarized as follows. First, a policy agenda about Long-term Care problem for the Elderly set up by the government-leading both Korea and Japan. and the number of policy participation(actors) increased to characteristics of policy process stage. but there is a difference between Korea and Japan in a background of setting up policy agenda about Long-term Care problem. Second, interaction among policy actors is corporative from early policy agenda establishment stage in Korea and Japan. but it changes to dissenting or critical rapidly as being announced the frame of system to the people. Also, it shows that main policy actors play a role in policy making decision and the connection structures of network is similar to both countries although it has a difference in the interaction frequency. Fourth, although the number of policy actors and the extent of their opinion reflection to the policy effect are different, it shows that policy network pattern is very similar to from policy agenda setting stage to parliament(The National Assemble) policy decision stage as a result of government-leading policy process. The theoretical and political implications of this study are as follows. The number and the variety of policy participation, the importance of establishing opened-interaction system, lots of limitation of policy making-decision process of Japan Long-term Care system, and exclusively the government-leading network has demerits about the reflection of too much government's opinion to the policy outcomes.

• Journal of Korea Multimedia Society
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• v.14 no.1
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• pp.121-132
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• 2011

A healthcare system is a type of medical information system that performs early detection and prevention in diseases by checking one's health condition periodically. Such a healthcare system is based on the signal obtained from the body. However, the developed existing system represents certain differences in the storage and description of vital signs according to medicare devices and the evaluation method of the system. It brings some disadvantages, such as lacks in the interoperability between systems, increases in the development cost of systems, and absence of a unified system. Thus, this study develops a healthcare system based on a meta model. For establishing this objective, this study describes and stores vital sign data based on the standard meta model of HL7 and applies OCL, which is a mathematical specification language, for defining wellness indexes and extracting data in order to evaluate health risk appraisals in health. In addition, this study implements components based on OSGi and assemble them in order to easily extend various devices and systems. By describing vital data based on the meta model, it represents some advantages that it makes possible to ensure the interoperability between systems and introduce the standardization of the evaluation method of health conditions through defining the wellness index using OCL. Also, it provides dear specifications.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.10
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• pp.1093-1100
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• 2014

The purpose of this paper is to suggest a weight-reduction design method for the hybrid carbody of a high-speed maglev train that uses aluminum extrusion profiles and sandwich composites. A sandwich composite was used on the roof as a secondary member to minimize the weight. In order to assemble the sandwich composite roof and aluminum extrusion side frame of the carbody using welding, a guide aluminum frame located at the four sides of the sandwich composite roof was introduced in this study. The clamping force of this guide aluminum frame was verified by three-point bending test. The structural integrity and crashworthiness of the hybrid carbody of a high-speed maglev train were evaluated and verified according to the Korean Railway Safety Law using a commercial finite element analysis program. The results showed that the hybrid carbody composed of aluminum extrusion frames and a sandwich composite roof was lighter in weight than a carbody made only of aluminum extrusion profiles and had better structural performance.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.73-75
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• 2013

Atomic force microscopy (AFM) [1] can now not only image individual atoms but also construct atom letters using atom manipulation method [2]. Therefore, the AFM is the second generation atomic tool following the well-known scanning tunneling microscopy (STM). The AFM, however, has the advantages that it can image even insulating surfaces with atomic resolution and also measure the atomic force itself between the tip-apex outermost atom and the sample surface atom. Noting these advantages, we have been developing a novel bottom-up nanostructuring system, as shown in Fig. 1, based on the AFM. It can identify chemical species of individual atoms [3] and then manipulate selected atom species to the designed site one-by-one [2] to assemble complex nanostructures consisted of many atom species at room temperature (RT). In this invited talk, we will introduce our results toward atom-by-atom assembly of composite nanomaterials based on the AFM at RT. To identify chemical species, we developed the site-specific force spectroscopy at RT by compensating the thermal drift using the atom tracking. By converting the precise site-specific frequency shift curves, we obtained short-range force curves of selected Sn and Si atoms as shown in Fig. 2(a) and 2(b) [4]. Then using the atom-by-atom force spectroscopy at RT, we succeeded in chemical identification of intermixed three atom species in Pb/Sn/Si(111)-(${\surd}3$'${\surd}3$) surface as shown in Fig. 2(c) [3]. To create composite nanostructures, we found the lateral atom interchange phenomenon at RT, which enables us to exchange embedded heterogeneous atoms [2]. By combining this phenomenon with the modified vector scan, we constructed the atom letters "Sn" consisted of substitutional Sn adatoms embedded in Ge adatoms at RT as shown in Fig. 3(a)~(f) [2]. Besides, we found another kind of atom interchange phenomenon at RT that is the vertical atom interchange phenomenon, which directly interchanges the surface selected Sn atoms with the tip apex Si atoms [5]. This method is an advanced interchangeable single atom pen at RT. Then using this method, we created the atom letters "Si" consisted of substituted Si adatoms embedded in Sn adatoms at RT as shown in Fig. 4(a)~(f) [5]. In addition to the above results, we will introduce the simultaneous evaluation of the force and current at the atomic scale using the combined AFM/STM at RT.

• Journal of Biomedical Engineering Research
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• v.38 no.3
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• pp.116-122
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• 2017

Physical breast phantoms would be useful for the development of a dedicated breast computed tomography (BCT) system and its optimization. While the conventional breast phantoms are available in compressed forms, which are appropriate for the mammography and digital tomosynthesis, however, the BCT requires phantoms in uncompressed forms. Although simple cylindrical plastic phantoms can be used for the development of the BCT system, they will not replace the roles of uncompressed phantoms describing breast anatomies for a better study of the BCT. In this study, we have designed a numerical voxel breast phantom accounting for the random nature of breast anatomies and applied it to the 3D printer to fabricate the uncompressed anthropomorphic breast phantom. The numerical voxel phantom mainly consists of the external skin and internal anatomies, including the ductal networks, the glandular tissues, the Cooper's ligaments, and the adipose tissues. The voxel phantom is then converted into a surface data in the STL file format by using the marching cube algorithm. Using the STL file, we obtain the skin and the glandular tissue from the 3D printer, and then assemble them. The uncompressed breast phantom is completed by filling the remaining space with oil, which mimics the adipose tissues. Since the breast phantom developed in this study is completely software-generated, we can create readily anthropomorphic phantoms accounting for diverse human breast anatomies.

• The KIPS Transactions:PartD
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• v.11D no.4
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• pp.937-950
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• 2004

With growing population of internet and web applications, distributed environment is considered to be the standard architecture of application. A network management systems(NMS) is necessary to control and monitor the complex network resources for providing and sharing the heft quality service. We recognize the NMS as a standard infrastructure for supporting efficient networking and a separate commercial applications. We believe every resource including software, hardware and environment for the network management should be separated from special protocols, vendors and applications. Therefore, We need a standard network management system that is efficient and consistent because of the heterogeous network features. In regards to software development, software reuse through assembling and extending the reusable elements such as patterns and components assures to realize the best productivity and quality The component based development(CBD) methodology that can assemble black box though well defined interfaces makes it possible to develop easer and quicker applications and is proved as the best software development solution involved in construction, selection and assembly of components. In this thesis, we describe the architecture for the network management and identify, define and design the components through analysis and design in the network management domain and Identified components mapped to the component architecture. We also specify the component development and design and implement the component for developing the network management. Implemented components apply to the component repository system that register, retrieve and understand the components. We analyze, design and implement the entire network management system based on configuration, connection, performance and fault management through the pre-developed components.

• Journal of the Korea Institute of Building Construction
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• v.14 no.6
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• pp.615-621
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• 2014

This study suggests the design and assembly drawing of the prefabricated precast concrete arch ammo magazines using the numerical analysis as well as the explosion verification test. The protective capacity of the proposed magazines is identified with the maximum support rotation angles measured by explosion verification tests according to the U.S. Unified Facility Criteria 3-340-02. Using numerical analysis, it is examined that oval-type members are better than the semi-circle ones in terms of protective capacity. Based on this numerical results, the design and assemble drawing for the prefabricated precast concrete arch ammo magazine are developed. It is identified that the structure constructed by invented design and assembly drawing has enough protective capacity against blast pressure caused by 133.75kg TNT explosion. The detonation point cannot be open due to the military security. In sum, it could be concluded that the ammo magazine proposed in this study has reliable protective capacity with enough redundancy. The redundancy means that there are more economic design approach with reducing the curved wall thickness.

• Journal of the Korea Concrete Institute
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• v.20 no.3
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• pp.271-282
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• 2008

Specific joint devices composed of end-plates and through bolts are under development to assemble steel beams to PC columns efficiently by dry construction method for the PCS structural system, of which major structural components are precast concrete columns and steel beams. Seismic performance of the joint devices had been evaluated by experimental tests in the previous studies and it was showed that all the performance requirements regarding to strength deterioration, stiffness degradation and energy dissipation capacity were satisfied to the criteria of ACI requirements, but the initial stiffness was not. In order to find out possible causes of the insufficient rigidity of the joint devices and provide the proper measures to improve the performance of the joint accordingly, numerical analyses were carried out by using ABAQUS. Parameters, such as thickness of neoprene pad, conditions of surface between PC column and end-plate, magnitude of pretension forces of through bolts, stiffness of end-plate were taken into consideration. As the result, it was found that the rigidity of the PCS system was negatively affected by the magnitude of initial gaps between PC columns and end-plates, and insufficient stiffness of neoprene fillers and end plates. In order to improve the initial stiffness performance of the joints, measures such as increase of the magnitude of pretension forces on through bolts and increase of the stiffness of end-plate by reducing the bolt pitch and providing adequate stiffeners are recommended.