• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1693-1698
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• 2015

The heterogeneous nature of lung cancer has become increasingly apparent since introduction of molecular classification. In general, advanced lung cancer is an aggressive malignancy with a poor prognosis. Activating alterations in several potential driver oncogenic genes have been identified, including EGFR, ROS1 and ALK and understanding of their molecular mechanisms underlying development, progression, and survival of lung cancer has led to the design of personalized treatments that have produced superior clinical outcomes in tumours harbouring these mutations. In light of the tsunami of new biomarkers and targeted agents, next generation sequencing testing strategies will be more appropriate in identifying the patients for each therapy and enabling personalized patients care. The challenge now is how best to interpret the results of these genomic tests, in the context of other clinical data, to optimize treatment choices. In genomic era of cancer treatment, the traditional one-size-fits-all paradigm is being replaced with more effective, personalized oncologic care. This review provides an overview of lung cancer genomics and personalized treatment.

• Journal of the East Asian Society of Dietary Life
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• v.1 no.3
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• pp.305-311
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• 1991

The study was designed to investigate overall acceptability of rice extrudate with added ginseng flour extruded by single screw extruder. Graphic three dimension analysis on response surface regression was conducted for overall acceptability evaluated by balanced incomplete block design. Overall acceptability, which formed a saddle point, increased as moisture content increased at lower die temperature, and as moisture content decreased at higher die temperature. Critical values of each variable which indicated optimum response are 5.0% ginseng content, 17.8% moisture content and 104.6$^{\circ}C$ die temperature, and optimum inferred score of overall acceptability is 59.6 and 90. Key words: extrdate, overall acceptability, response surface regression analysis, balanced incomplete block method.

• Asian review of World Histories
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• v.4 no.1
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• pp.125-132
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• 2016

This paper, as a conlcusion to this special issue, presents the future work that is being carried out at NTU Singapore in collaboration with Microsoft Research and Microsoft Azure for Research. For our research team the real frontier research in world histories starts when we want to use computers to structure historical information, model historical narratives, simulate theoretical large scale hypotheses, and incent world historians to use virtual assistants and/or engage them in teamwork using social media and/or seduce them with immersive spaces to provide new learning and sharing environments, in which new things can emerge and happen: "You do not know which will be the next idea. Just repeating the same things is not enough" (Carlo Rubbia, 1984 Nobel Price in Physics, at Nanyang Technological University on January 19, 2016).

• Asian-Australasian Journal of Animal Sciences
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• v.11 no.3
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• pp.255-259
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• 1998

Sixteen Friesian Cows were allocated equally into 4 groups in a $4{\times}4$ Latin square design to evaluate the effects of utilizing bean by-products on the feed intake and milk production. Cows were fed on 4.5% of their body weight fresh alfalfa; the remainder of their requirements were covered by one of 4 experimental concentrate treatments: 1) commercial concentrate (CC), 2) 70% CC + 30% bean hulls (BH), 3) 70% CC + 30% Polished bean (PB) and 4) 70% CC+ 15% BH + 15% PB. Results showed that the inclusion of bean hulls at 30% improved (p<0.05) milk yield, 4% fat corrected milk yield, feed conversion ratio and fat percent of the milk over the other treatments. Feeding cows on a commercial concentrate plus 30% BH or 30% PB or 15% from each of BH and PB decreased the cost of feed per kg milk by 13.6, 2.5 and 1.3 %, respectively, lower than those fed on the commercial concentrate.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.5
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• pp.695-698
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• 2006

Six, one-year old dairy steers were randomly divided into two groups according to a Completely randomized design (CRD) to receive high-quality feed block (HQFB) without cassava hay and drenching (HQFB1+Ivomex) and HQFB with cassava hay (HQFB2) as block licks while grazing on Ruzi grass pasture. During the eight weeks, fecal parasitic egg counts dramatically declined for both treatment groups with 63.2 and 27.6% reduction from initial period for HQFB1+Ivomex and HQFB2, respectively. However, digestion of coefficients of nutrients particularly OM, were significantly higher in HQFB2 than, those in HQFB1+Ivomex, in addition, ADG of animals in HQFB2 tended to be higher than the group on HQFB1. It was, hence concluded that cassava hay could not only provide as a protein source but also serve as an anthelmintic in ruminants.

• Asian Journal of Business Environment
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• v.9 no.4
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• pp.29-34
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• 2019

Purpose - The purpose of the research is to assess the current state of cryptocurrency in Vietnam and to provide several solutions and recommendations to the Government, the State Bank of Vietnam (SBV) and other relevant agencies for monitoring, managing, and controlling cryptocurrency effectively and efficiently. Research design, data and methodology - The study is based on the assessment and analysis of cryptocurrency in the world and the real situation of cryptocurrency in Vietnam in order to provide solutions to the controllable development of operation of this currency. Results - The study indicates the current operations of cryptocurrency in Vietnam and provides several suggestions to effectively control this currency. Conclusion - According to the study on current cryptocurrency and the situation of cryptocurrency in Vietnam, the author has proposed a number of solutions to provide suggestions to manage and develop the operations of cryptocurrency in a most practical manner. The governments of many countries in the world, including the Government of Vietnam, need more time as well as appropriate technology improvements to take advantage of these new digital currencies; therefore, they still need to ensure safety in compliance with the control and regulatory capabilities of the central government and central banks.

• Asian-Australasian Journal of Animal Sciences
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• v.9 no.1
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• pp.101-106
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• 1996

This experiment was conducted to investigate the effect of bST administration on growth performance and carcass characteristics of finishing Korean native bulls. Fifty four Korean native bulls of about 14 months of age weighting an average 420 kg were assigned to receive no injection of bST, 250 mg of bST s.c. injection every week, or 500 mg bST s.c. injection every 2 weeks (Control, 250ST, 500ST) in a $3{\times}3$ randomized block design for a period of 20 weeks Animals administered with bST responded with decreased feed DMI by 8%(p < 0.01), increased ADG by 12%(p < 0.05), and increased gain/feed ratio by 20%(p < 0.01). But there was no significant difference in the growth performance between 250ST and 500ST. Administration of bST increased dressing percentage by 1.8%(p < 0.05), and tended to increase longissimus muscle area and decrease backfat thickness and marbling score.

• Asian Journal of Innovation and Policy
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• v.6 no.3
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• pp.332-353
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• 2017

This paper highlights how Thailand upgrades its positions in global value chains in high-tech, mid-tech and low-tech industries represented by electronics, automotive and frozen seafood, respectively. In the electronics industry, there are not many capable firms in the upstream segment like semiconductors. Nevertheless, transnational corporations in segment like hard disk drive began to invest in process R&D and collaborate more with local suppliers, universities and public research institutes in human resource and technological development. In the automotive industry, several Japanese car manufacturers such as Toyota, Honda, Nissan, and Isuzu set up R&D/Technical centres in Thailand since 2000s. This prompted Japanese and local part suppliers to also invest more in engineering, design and development activities. Some local universities offer as well engineering programmes specifically targeting the automotive industry. In the frozen seafood industry, several Thai firms have developed new ready-to-eat products, own brands and international distribution networks. They started to become transnational corporations investing in both developing and developed countries.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8307-8311
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• 2016

Lung cancer is one particular type of cancer that is deadly and relatively common than any other. Treatment is with chemotherapy, radiation therapy and surgery depending on the type and stage of the disease. Focusing on drugs used for chemotherapy and their associated side effects, there is a need to design and develop new anti-lung cancer drugs with minimal side effects and improved efficacy. The pharmacophore model appears to be a very helpful tool serving in the designing and development of new lead compounds. In this paper, pharmacophore analysis of 10 novel anti-lung cancer compounds was validated for the first time. Using LigandScout the pharmacophore features were predicted and 3D pharmacophores were extracted via VMD software. A training set data was collected from literature and the proposed model was applied to the training set whereby validating and verifying similar activity as that of the most active compounds was achieved. Therefore pharmacophore develoipment could be recommended for further studies.

• Asian Journal for Public Opinion Research
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• v.4 no.2
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• pp.88-107
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• 2017

Background: Adolescent mothers may find the transition to motherhood to be Aim: The aim of this study was to investigate the viewpoints of nurse managers and directors of nursing services in community hospitals regarding the essential competencies of head nurses. Methods: A qualitative descriptive design was used to investigate the perspective of nurse managers and directors of nursing services about essential competencies of nurse managers in community hospitals. A total of ten participants (four directors of nursing services and six nurse managers) were interviewed. Findings: Nurse managers and directors of nursing services identified leadership, management, communication, professional ethics, and policy and healthcare environment as the essential competencies for their positions in community hospitals. Conclusions: These findings can be used by executives of community hospitals and nursing institutes to plan for competency development for nurse managers. They should be included in nursing administration programs.