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Establishment of Reference Value of Insulin Using the Statistical Analysis (통계적 분석을 통한 Insulin의 정상 참고치 설정)

  • Kim, Whe-Jung;Yoon, Pil-Young;Shin, Young-Goon;Yoo, Seon-Hee;Cho, Shee-Man
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.1
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    • pp.143-146
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    • 2010
  • Purpose: Insulin is involved in carbohydrate metabolism and also it's very important because it increases storage of glycogen, synthesis of fatty acids, absorption of amino acid, synthesis of protein. Insulin is clinically useful when we evaluate fasting patients in hypoglycemia, classify and predict diabetes, assess the activity of ${\beta}$-cell, research insulin resistance. We are going to increase usability of insulin assay by establishing normal reference value according to statistical analysis. Material & Method: We selected 6,648 patients who visited asan health medical center from May to August in 2008. We set exclusion criteria as family of diabetes, diabetes medication, the past history of blood glucose rise, more than 100 mg/dL in normal fasting blood glucose, outside the scope of BMI 18.5~22.9 $kg/m^2$, and more than HbA1c 6.5%. We determine whether the subgroup is portioned as sex and age or not and establish normal reference value by conducting statistical analysis as Bayesian's method and Hoffman's method. Result: Portioning of subgroup as sex and age is not needed. By statistical analysis of Bayesian method, results 1.5-11.0 uIU/mL. By statistical analysis of Hoffman method, results 1.8~12.8 uIU/mL. Conclusion: We established 1.8~12.8 uIU/mL as Insulin normal reference value by Hoffman method. This is a similar value with reporting reference value 1.7~11.8 uIU/mL in kit. This will enhance the usability of insulin assay by establishing normal reference value.

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A Study of Sitting Areas Preferred to Use by Assisted Living Residents in the U.S. (미국 노인 생활지원시설 거주자의 공용공간 이용선호 특성 연구)

  • Lee, Min-Ah
    • Korean Journal of Human Ecology
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    • v.22 no.3
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    • pp.493-509
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    • 2013
  • This study investigated the sitting areas preferred to use by assisted living residents in the U.S., compared the perceptions of staff and residents, and analyzed the effects of residents' and spatial characteristics on the preference for use of main sitting areas such as lounge, dining area, activity room and outdoor area. A total of 102 participants(66 residents and 36 staff) from eight facilities in the seven counties of southern Texas were asked about two sitting areas residents like to spend time at. The results of the study were as follows: The most frequently mentioned sitting areas were the activity and outdoor area as per the residents, but the dining area and lounge as per the staff. It might be due to that the view of staff might have been limited to sitting areas usually used by the severely frail residents. Residents using higher level of mobility assistance such as wheelchairs and walkers, or living in the facility having more dispersed sitting areas were less likely to prefer to use the lounge. The residents who were younger or having good centralized outdoor area were more likely to prefer to use the outdoor area. The preference for use of dining area was affected by its proximity from the residents' individual rooms. Diverse survey methods need to be developed for a more in-depth collection and analysis of data from functionally frail older residents and staff caring for them.

Epidemiology, Etiology, Diagnosis and Treatment of Prostate Cancer

  • Daniyal, Muhammad;Siddiqui, Zamir Ali;Akram, Muhammad;Asif, H.M.;Sultana, Sabira;Khan, Asmatullah
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9575-9578
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    • 2014
  • Prostate cancer is more common in men over the age of 65 years. There are 15% cases with positive family history of prostate cancer Worldwide. Prostate cancer is the second leading cause of death among the U.S. men. Prostate cancer incidence is strongly related to age with the highest rates in older man. Globally millions of people are suffering from this disease. This study aims to provide awareness about prostate cancer as well as an updated knowledge about the epidemiology, etiology, diagnosis and treatment of prostate cancer.

Experimental Determination of Friction Characteristics for Advanced High Strength Steel Sheets (초고강도강판 마찰특성의 실험적 규명)

  • Kim, N.J.;Keum, Y.T.
    • Transactions of Materials Processing
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    • v.22 no.4
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    • pp.223-228
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    • 2013
  • The friction coefficients of advanced high strength steel sheets were experimentally determined. In the friction test, the pulling and holding forces acting on the sheet for various friction conditions, such as lubricant viscosity, pulling speed, blank holding pressure, sheet surface roughness, and hardness of the sheet were measured and the friction coefficient was calculated based on Coulomb's friction law. While the friction coefficient, generally, decreases as the value of friction factor increases, the factor associated with the sheet surface roughness shows U shape behavior for the friction coefficient. Furthermore, the relationship between friction coefficient and the wear volume, which was computed for the roughness of both sheet surfaces and the friction area, is linearly proportional.

Studios on Fluorine Compounds among the Air Pollutants (대기오염물중(大氣汚染物中) 불화물(弗化物)에 관(關)한 연구(硏究) (I))

  • Lee, Pyong-Kap;Kim, Hyong-Suk
    • Journal of Preventive Medicine and Public Health
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    • v.4 no.1
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    • pp.31-34
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    • 1971
  • This study was conducted by the Dept. of Preventive Medicine, Kyung Hee University, School of Medicine as a preliminary test for the effects of Fluorine Compounds to the Plants from April through August, 1971. Fluorine was measured with Zirconium-Alizarine method and the following findings could be obtained: 1. Most high densities (25.7 pptm) was found around the industrial areas and lowest (19.3 pptm) around residential sections in Seoul. 2. Average density of Fluorine in the atmosphere of Seoul City was 22.3 pptm which can damage such plants as Pine, Strawberry, Peach and Grapes. 3. Fluorine contents (22.3 pptin) in Seoul area atmosphere shows about 4 times more than that of Cincinnati, Ohio, U. S. A.

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The Influence of Additional Marketing-Mix on Customer's Overall Satisfacton in Family Restaurant (패밀리레스토랑의 추가마케팅믹스가 고객의 전반적인 만족도에 미치는 영향)

  • Kim, Mi-Yon;Yoon, Tae-Hwan
    • Journal of the Korean Society of Food Culture
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    • v.22 no.5
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    • pp.575-581
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    • 2007
  • The purpose of this study was to investigate the influence of additional marketing mix on overall satisfaction of customers at family restaurants in Seoul and Kyongki-province. In this research frequency analysis, reliability analysis, factor analysis, multiple-regression analysis were employed to analyze the data. Additional marketing mix were divided into 3 factors. Employee(${\beta}=0.352$, t(p)=7.221(0.000) had the most positive impact on overall satisfaction. And physical evidence(0.160, t(p)=3.271(0.001) and process(${\beta}=0.114$, t(p)=2.338(0.020) influenced positively(+) in order. As a result, all factors of additional marketing mix influenced significantly overall satisfaction of customers. These additional marketing mix are regarded as effective marketing tactic to reduce intangibility of food-service business. Therefore restaurant company needs to manage additional marketing mix sufficiently to maintain of customers' satisfaction at family restaurants.

Energy budget of sandfish juvenile, Arctoscopus japonicus reared at different diet conditions and water temperature (수온과 먹이에 따른 도루묵 (Arctoscopus japonicus) 치어의 에너지수지)

  • Yang, Jae-Hyeong;Lee, Sung-Il;Yoon, Sang-Chul;Kim, Jong-Bin;Chun, Young-Yull;Park, Kie-Young
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.47 no.2
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    • pp.128-138
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    • 2011
  • In this study, energy budget was estimated to produce an efficient artificial seed. And it needs to enhance fisheries productivity of sandfish, A. japonicus. In order to estimate energy budget of the sandfish, A. japonicus juvenile fed on nonriched Artemia nauplii (NA) and the enriched Artemia nauplii (EA), of sandfish were reared at constant condition of seawater temperature of natural temperature (NT) and heated temperature (HT). During the reared period, energy used by the reared juveniles were calculated from estimates of data on ingestion, growth, oxygen consumption, nitrogen excretion and energy content. Energy budget of NT-NA, NT-EA, HT-NA and HT-EA were represented as 100C=66.49G+21.28M+0.78F+1.44U, 100C=67.54G+21.40M+9.39F+1.67U, 100C=66.86G+22.66M+8.01F+2.47U and 100C=67.06G+22.96M+7.70F+2.28U. The assimilation efficiency estimated NT-NA, NT-EA, HT-NA and HTEA were represented as 87.78%, 88.94%, 89.52% and 90.02%. Gross growth efficiency estimated NT-NA, NT-EA, HT-NA and HT-EA were represented as 66.49%, 67.54%, 66.86% and 67.06%. Net growth efficiency estimated NT-NA, NT-EA, HT-NA and HT-EA were represented as 75.75%, 75.94%, 74.68% and 74.49%. In this results, two ways could be considered to produce an efficient artificial seed of sandfish. To hasten the growth of sandfish juvenile, heated seawater (HT) and enriched Artemia nauplii (EA) should be inputted to reared condition. And to increase the energy efficiency, natural seawater (NT) and enriched Artemia nauplii (EA) should be inputted to reared condition.

Growth Characteristics of Zelkova serrata Seedlings as Affected by Mixed Nursery Soil (상토의 조성에 따른 느티나무 묘목의 생육특성)

  • Lee, U.Y.;Youn, K.K.;Shim, Y.J.;Lee, EJ.;Lee, K.C.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.22 no.2
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    • pp.17-22
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    • 2020
  • This study was conducted to find out the optimum composition of nursery soil for raising seedling of Zelkova serrata. The treatments were regulated with the three different soil types : full peat moss(PM 100%), peat moss + perlite + vermiculite(1:1:1), peat moss + perlite + vermiculite(1:2:1). The full peat moss(PM 100%) showed the highest photosynthetic activity such as maximum photosynthesis rate(PN max), water use efficiency(WUE), Fv/Fm, PIabs and SPAD value. And also, full peat moss(PM 100%) showed relatively better growth performances. As a result of surveying the whole experiment, full peat moss(PM 100%) soil increases growth performances and enhances overall quality.

Toll-like receptor 2 promotes neurogenesis from the dentate gyrus after photothrombotic cerebral ischemia in mice

  • Seong, Kyung-Joo;Kim, Hyeong-Jun;Cai, Bangrong;Kook, Min-Suk;Jung, Ji-Yeon;Kim, Won-Jae
    • The Korean Journal of Physiology and Pharmacology
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    • v.22 no.2
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    • pp.145-153
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    • 2018
  • The subgranular zone (SGZ) of hippocampal dentate gyrus (HDG) is a primary site of adult neurogenesis. Toll-like receptors (TLRs), are involved in neural system development of Drosophila and innate immune response of mammals. TLR2 is expressed abundantly in neurogenic niches such as adult mammalian hippocampus. It regulates adult hippocampal neurogenesis. However, the role of TLR2 in adult neurogenesis is not well studied in global or focal cerebral ischemia. Therefore, this study aimed to investigate the role of TLR2 in adult neurogenesis after photochemically induced cerebral ischemia. At 7 days after photothrombotic ischemic injury, the number of bromodeoxyuridine (BrdU)-positive cells was increased in both TLR2 knock-out (KO) mice and wild-type (WT) mice. However, the increment rate of BrdU-positive cells was lower in TLR2 KO mice compared to that in WT mice. The number of doublecortin (DCX) and neuronal nuclei (NeuN)-positive cells in HDG was decreased after photothrombotic ischemia in TLR2 KO mice compared to that in WT mice. The survival rate of cells in HDG was decreased in TLR2 KO mice compared to that in WT mice. In contrast, the number of cleaved-caspase 3 (apoptotic marker) and the number of GFAP (glia marker)/BrdU double-positive cells in TLR2 KO mice were higher than that in WT mice. These results suggest that TLR2 can promote adult neurogenesis from neural stem cell of hippocampal dentate gyrus through increasing proliferation, differentiation, and survival from neural stem cells after ischemic injury of the brain.

Deposition of Uranium Ions with Modified Pyrrole Polymer Film Electrode (우라늄이온 포집을 위한 수식된 피를 고분자 피막전극)

  • Cha Seong-Keuck;Lee Sang Bong
    • Journal of the Korean Electrochemical Society
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    • v.3 no.3
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    • pp.141-145
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    • 2000
  • Anodically Polymerized conducting Polypyrrole film electrode was employed to Pick up uranyl ion with the type of Gr/ppy, xylenol orange modified electrode. To have Porous and oriented ppy film, NBR was applied as precoating agent. The rate constant of polymerization was $3.22\times10^{-3}s^{-1}$ which was 1.6 times smaller value than bare graphite surface. The deposited amount of uranyl iou on $1.70Ccm^{-2}$ of ppy was $1.55\times10^{-4}g$. The matrix effect in artificial seawater was $6.8\%$. The polymer film electrode has a diffusion controlled process in conduction, but the modified Gr/ppy, $X.O^{4-}UO^+$ type was influenced on the ion doping and electronic conduction of film itself owing to increasing of impedance. The capacitance of electrical double layer was respectively enhanced to 56 and 130 times in Gr/ppy, $X.O.^{4-}$ and Gr/ppy, $X.O^{4-}UO^+$ than Grippy type electrode.