• YAKHAK HOEJI
• /
• v.37 no.3
• /
• pp.270-277
• /
• 1993

It is well known that lipidperoxide, formed in vivo, induced the denaturation of enzyme and destruction of cell membrane to acute injury of tissue. Aralia elata have physiological activates, the improvement of lipid metabolism, antidiabetic activity etc., which was thought to have the relationship to lipid peroxidation. The anti-lipidperoxidative effect of Aralia elata have not yet established. In this study, we examined the anti-lipidperoxidative effects of Aralia elata (Butanol fraction) on CCI$_{4}$ induced lipidperoxidation in rats, and elucidated the anti-lipidperoxidative mechanism. In rat liver homogenate intoxicated with CCI$_{4}$ (0.5 ml/100g), BuOH fraction of Aralia elata (80 mg/Kg/day) exhibited 85.41% anti-lipidperoxidative effect but in serum 69.63% inhibitory effects, respectively. In mitochondrial and microsomal fraction showed inhibition of 55.85% and 69.30%, respectively. In order to elucidate the mechanism of anti-lipidperoxidation effects of Aralia elata, enzymatic (NADPH dependent) and non-enzymatic (Ascorbic acid catalyzed) reaction, in vitro, were performed. In enzymatic reation, Aralia elata exhibited 59.43% anti-lipidperoxidation effects, but in non-enzymatic reaction exhibited 43.27% inhibition. Therefore, it is noteworthy that antioxidative power of them may mainly results from the inhibition by enzymatic reaction.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.33 no.4
• /
• pp.653-658
• /
• 2004

Oxidative stress is currently suggested as a mechanism underyling diabetes. Accordingly, the present study was designed to evaluate the effect of Aralia elate water extracts (AEW) on activities of hepatic oxygen free radical generating and scavenging enzymes in streptozotocin (STZ)-induced diabetic rats. Male Wistar rats divided into nondiabetic group, diabetic group, and diabetic-AEW supplemented group. The extract was supplemented in 1.14% of raw Aralia elata/kg diet for 7 weeks. Diabetes was induced by injecting STZ (55 mg/kg BW, ip) once 2 weeks before sacrifying. The hepatic cytochrome P-450 content, xanthine oxidase and aminopyrine N-demethylase activities were significantly lowered in the diabetic group compared to the nondiabetic group. Whereas, the activities of aniline hydroxylase and oxygen free radical scavenging enzymes, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose-6-phosphate dehydrogenase and glutathione S-transferase, were significantly higher in the diabetic group than in the nondiabetic group. However, the supplementation of AEW normalized these enzyme activities in STZ-induced diabetic rats. When the AEW was supplemented with the diabetic rats, hepatic glutathione content was markedly elevated as well as lipid peroxide level was significantly lowered compared to those of the diabetic group. Thus, these results suggested that AEW supplement enhanced the activities of oxygen species metabolizing enzymes in STZ-induced diabetic rats.

• The Korean Journal of Community Living Science
• /
• v.16 no.3
• /
• pp.17-24
• /
• 2005

This study was carried out to investigate the kinds of fresh wild vegetables, the number of street stalsl, seller's age, and the selling list of items of the street stall in the five-day traditional markets of Gyeongnam Tongyoung and Namhae, Jeonnam Naju and Younggwang, Jeonbuk Iksan and Jangsu, from March to May, 2005. The number of street stalls selling fresh wild vegetables was forty nine in Tongyoung, twenty five in Namhae, thirty in Naju, eighteen in Younggwang, one hundred and thirty in Iksan, and seventeen in Jangsu. The selling lists of items totaled forty items; thirty in Tongyoung, seventeen in Namhae, twenty in Naju, sixteen in Younggwang, twenty seven in Iksan, and thirteen in Jangsu. The main kinds were Aster scaber, Aralia elata, Pteridium aquilinum var. latusculum, Artemisia princeps, Sedum sarmentosum, Oenanthe javanica, Pla쇼codon grandiflorum, Petasites japonicus and Allium monanthum. sprouts or woody plants such as Arazia elate, Ailanthus altissima, Meliosma oldhamii, and Kalopanax pictus were also being sold. About $80{\%}$ of the sellers were over fifty one years old. Half of the sellers were at least sixty years old. More thab $77\%$ of the street stalls in the traditional markets sell fewer than four kinds of fresh wild vegetables.