• Title/Summary/Keyword: Araceae

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Toxicological Evaluation of Medicinal Plants Used for Herbal Drugs (IV) -Acute Toxicity and Antitumor Activities- (한국산 생약의 약리작용 및 독성연구 (제4보) -급성독성 및 항암작용-)

  • Chang, Il-Moo;Kim, Jae-Hoon;Han, Dae-Suck
    • Korean Journal of Pharmacognosy
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    • v.13 no.2
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    • pp.62-69
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    • 1982
  • Fiftythree species(35 families and 52 genera)of Korean medicinal plants which have been frequently used in oriental herb prescriptions or have been used as folklorics were evaluated on their short term acute toxicity and potential antitumor activities against P-388 murine lymphocytic leukemia model in vivo. Among these plants Acorus gramineus (Araceae), Agrimonia pilosa (Rosaceae), Aralia elata (Araliaceae), Dryopteris crassirhizoma (Aspidiaceae), Syringa reticulata (Oleaceae) and Calystegia japonica (Convolvulaceae) exhibited potent acute toxicity resulting from severe weight loss and death. Agrimonia pilosa (Rosaceae) showed about 33% of increased life span in comparison with that of control group mouse, but others exhibited no significant antitumor activities.

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Sedative Effects of the Essential Oil from Acorus gramineus upon Inhalation

  • Koo, Byung-Soo;Lim, Jae-Chul;Park, Jong-Hee;Lee, Dong-Ung
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.273.2-274
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    • 2003
  • The present study was designed to evaluate central inhibitory effects of an essential oil from Acori graminei Rhizoma (AGR), the dry rhizomes of Acorus gramineus Solander (Araceae) upon fragrance inhalation (aroma therapy). Preinhalation of an essential oil of AGR markedly delayed the appearance of pentylenetetrazole-induced convulsion. Furthermore, the inhalation of an essential oil of AGR impressively inhibited the activity of ${\gamma}$-aminobutyric acid (GABA) transaminase, a degradating enzyme for GABA as inhalation period is lengthened. (omitted)

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A Study on the Herb Plant Resources in Jeonnam II. Investigation of the Herb Plant Resources around Mt. Jogho (전남지역 한약자원 식물수집분포 및 이용체계에 관한 연구 III. 조계산 한약자원 식물분포 조사)

  • 이종일
    • Korean Journal of Plant Resources
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    • v.1 no.1
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    • pp.93-116
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    • 1988
  • The plants medicinal resourees of Mt. Joghe were investigeted 10 times from January, 1988 to October, 1988. In order to analyze the vegetation of Joghemountain area, herb plants structure and distribution. Herb plants of Joghe moun-tain consisted of 102 families, 265 species in all. The resources of important herbdrugs were Gramineae, Cyperaceae Oleaceae, Araceae, Polygonaceae, Caryophyllaceae,Ranunculaceae, Theaceae, Cruciferae, Liliaceae, Rosaceae, Geranjaceae, Violaceae,Vitaceae, Umbelliferae, Labiatae, Solanaceae, Campanulaceae, Rutaceae, Compositae,Dioscoreaceae, Fagaeeae, Moraceae, Anacardiaceae, Legum inosae, Cupressaceae, andJuelandaceae. The herb drugs were comparatively more than in other mountains inour country.

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Vascular Plants of Taebaeksan, Hambaeksan, Geumdaebong(Peak) and Maebongsan in the Baekdudaegan (백두대간 태백산, 함백산, 금대봉 및 매봉산지역의 관속식물상)

  • 김용식;임동옥;오현경;신현탁
    • Korean Journal of Environment and Ecology
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    • v.15 no.4
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    • pp.293-318
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    • 2002
  • As one of the botanical hot spots of the Korean peninsula, the vascular plant species in the areas of Taebaeksan, Hambaeksan, Geumdaebong(Peak) and Maebongsan were summarized as 694 taxa, 89 families, 302 genus, 579 species. 102 varieties and 13 forms. Based on the list of rare and endangered plants from the Forest Research Institute and the Ministry of Environment, 22 species were recorded in the studied areas: Thuja koraiensis(Cupressaceae), Arisaema heterophyllum(Araceae), Disporum ovale(Liliaceae), Tricyrtis dialata(Liliaceae), Lilium distichum(Liliaceae), Anemone koraiensis(Ranunculaceae), Rodgersia podophylla(Saxifragaceae), Rosa marretii(Rosaceae), Viola diamantica(Violaceae), Viola albida(Violaceae), Echinopanax horridum(Araliaceae), Acanthopanax chiisannensis(Araliaceae), Lysimachia coreana(Prinmulaceae), Syringa velutina var. kamibayashii, Halenia corniculata(Gentianaceae), Partrinia saniculaefolia(Valerianaceae), Adenophora grandiflora(Campanulaceae), Cacalia pseudo-taimingasa(Compositae) Iris odaesanensis(Iridaceae), Leontice microrhyncha(Berberidaceae), Rpdgersia tabularis(Saxifragaceae), and Acanthopanax sentico년(Araliaceae), Among them the four species were recorded from the list of the Ministry of Environment. As most of the species were recorded from the mountain-trails, the long-term habitat monitoring for the species is required .

New Ceramide from Alocasia macrorrhiza

  • Tien, Nguyen Quyet;Ngoc, PhamHoang;Minh, Pham Hong;Kiem, Phan Van;Minh, Chau Van;Kim , Young-Ho
    • Archives of Pharmacal Research
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    • v.27 no.10
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    • pp.1020-1022
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    • 2004
  • A new ceramide alomacrorrhiza A was isolated from the ethanolic extract of the plant Alocasia macrorrhiza (L.) Schott. Its chemical structure was elucidated as (2S,3S,4R)-2N-[(2'R)-2'- hydroxy-hexacosanoyl]-tetradecane-1,3,4-triol based on extensive 1D, 2D NMR, EI-MS, FABMS, HR-FAB-MS spectroscopic data and chemical degradation studies.

A Tuber Lectin from Arisaema jacquemontii Blume with Anti-insect and Anti-proliferative Properties

  • Kaur, Manpreet;Singh, Kuljinder;Rup, Pushpinder Jai;Kamboj, Sukhdev Singh;Saxena, Ajit Kumar;Sharma, Madhunika;Bhagat, Madhulika;Sood, Sarvesh Kumar;Singh, Jatinder
    • BMB Reports
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    • v.39 no.4
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    • pp.432-440
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    • 2006
  • A tuber lectin from Arisaema jacquemontii Blume belonging to family Araceae was purified by employing a single step affinity chromatography using column of asialofetuin-linked amino activated silica beads and the bound lectin was eluted with 100 mM glycine-HCl buffer pH 2.5. The purified A. jacquemontii lectin (AJL) showed a single protein band with an apparent molecular mass of 13.4 kDa when submitted to SDS-polyacrylamide gel electrophoresis under reducing as well as non-reducing conditions. The native molecular mass of AJL determined by gel filtration on a Biogel P-200 column was 52 kDa and its carbohydrate content was estimated to be 3.40%. Thus AJL is a tetrameric glycoprotein. The purified lectin agglutinated erythrocytes from rabbit but not from human. Its activity was not inhibited by any of the mono- and disaccharides tested except N-acetyl-D-lactosamine having minimal inhibitory sugar concentration (MIC) 25 mM. Among the glycoproteins tested only asialofetuin was found to be inhibitory (MIC $125\;{\mu}g/mL$). A single band was obtained in native PAGE at pH 4.5 while PAGE at pH 8.3 showed two bands. Isoelectric focusing of AJL gave multiple bands in the pI range of 4.6-5.5. When incorporated in artificial diet AJL significantly affected the development of Bactrocera cucurbitae (Coquillett) larvae indicating the possibility of using this lectin in a biotechnological strategy for insect management of cucurbits. Larvae fed on artificial diet containing sub-lethal dose of AJL showed a significant decrease in acid phosphatase and alkaline phosphatase activity while esterase activity markedly increased as compared to larvae fed on diet without lectin. Out of various human cancer cell lines employed in sulphorhodamine B (SRB) assay, this lectin was found to have appreciable inhibitory effect on the in vitro proliferation of HCT-15, HOP-62, SW-620, HT-29, IMR-32, SKOV-3, Colo-205, PC-3, HEP-2 and A-549 cancer cell lines by 82, 77, 73, 70, 41, 41, 37, 29, 21 and 21% respectively.

Investigation of the Medicinal Plant Resources (약용식물(藥用植物)의 유전자원수집(遺傳資源蒐集)과 이용(利用)에 대(對)한 조사(調査))

  • Lee, Joon Tak
    • Current Research on Agriculture and Life Sciences
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    • v.8
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    • pp.71-82
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    • 1990
  • In order to collect the plant genetic resources in Korea, the medicinal plants were surveyed from 1987 to 1989 in Kyungbuk province and at the several areas in Kyuognam and Choongbuk province. The medicinal plants of 456 species in 118 families were investigated in these regions. Among them, 249 species were belonged to 19 families, Compositae, Liliaceae, Leguminosae, Poiygonaceae, Labiatae, Rosaceae, Umbelliferae, Gramineae, Solanaceae, Cucurbitaceae, Ranunculaceae, Cruciferae, Rutaceae, Araliaceae, Araceae, Moraceae, Scrophulariaceae, Caryopyhllaceae, and Convolvulaceae, and others were belonged to 99 families. They have been used mostly for urination, gastroenteric disoder, robustness, antiphlogistic, anodyne, cough medicine, fever remedy, hemostatic, and 9 species of them have been used for anticancer medicine. The medicinal plant resources which were planted in the fields, gardens, parks, roadsides, and glass house, were 93 species for ornamental, 50 for medicine, 27 for vegetable, 14 for food, 5 for vegetable fruit, 13 for fruit, 5 for oil, 6 for tea, 9 for shade, and 14 for other purposes. Most of investigated plants were perennial, and flowered from June to August. The root parts were most frequently used as medicine, and other parts were used in the order of leaf and stem, whole plants, flower, seed, and fruit. Among the 456 species, 191 species in 87 families were investigated to be important medicinal plants.

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Utilization of [6]-gingerol as an origin discriminant marker influencing melanin inhibitory activity relative to its content in Pinellia ternata (반하(Pinellia ternata)에서의 [6]-gingerol 함량과 멜라닌 저해 활성에 영향을 미치는 원산지 판별 마커로의 활용)

  • An, Ju Hyeon;Won, Hyo Jun;Seo, Soo-Kyung;Kim, Doo-Young;Ku, Chang-Sub;Oh, Sei-Ryang;Ryu, Hyung Won
    • Journal of Applied Biological Chemistry
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    • v.59 no.4
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    • pp.323-330
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    • 2016
  • Pinellia ternata Breitenbach, the natural medicinal plant of the Araceae family, is a perennial plant originated from the East Asia, but also widely distributed in Europe and North America. Its tuber is used as traditional medicine for treatment of various diseases such as vomiting, inflammation, and traumatic injury. Pharmacological studies revealed that P. ternata possesses anticonvulsant, anti-tumor, insecticidal, and cytotoxic activities. Despite being well-known as the useful medicinal plant, there is no reliable, standardized method for origin discrimination. Ultra performance liquid chromatography-photodiode array detector and quadrupole time of flight-mass spectrometry based metabolite-profiling was applied to explore significant metabolite for origin discrimination between Korean and Chinese P. ternata. One compound was isolated from Korean P. ternata using repeated ODS column chromatography by bioactivity guided fractionation, and determined as [6]-gingerol according to the results of spectroscopic data including nuclear magnetic resonance and MS. This compound was selected as cosmeceutical biomarker by fingerprints, and it was associated to melanin inhibitory effect determining its origin authenticity. Furthermore, the calibration curve of biomarker was prepared using validated method for the comparison of content between Korean and Chinese P. ternata. This is the report to address the selection and successful validation of the discriminant metabolite for confirmation of Korean P. ternata.

Recent advances in pharmacologic study of anticancer natural products from medicinal plants in Morocco

  • Bnouham, Mohamed
    • CELLMED
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    • v.2 no.3
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    • pp.22.1-22.9
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    • 2012
  • The aim of this study is to collate all available data on experiments reporting the antiproliferative, cytotoxic effects of plants and natural products in Morocco in the last two decades. A bibliographic investigation was carried out by analyzing recognized books and peer-reviewed papers, consulting worldwide accepted scientific databases (Scirus, Embase, HighWire, MEDLINE/PubMed, LILACS, Ovid, ScienceDirect, SciELO, Google Scholar). We used medical subject heading terms and the words 'anticancer', 'antiproliferative', 'antineoplastic', 'antitumoral', 'cytotoxic', 'Morocco', to identify relevant articles. Moroccan plants with attributed anti-cancer properties studied as plant extracts that have been evaluated for cytotoxic effects, antitumoral effects, plants with active compounds tested on cancer cell lines, and plants with active compounds that have been assayed on animal models were chosen for this research. In the present study, interest is focused on experimental research conducted on medicinal plants, particularly those which show antiproliferative or cytotoxic activities alongside bioactive components. A total of 20 plant species belonging to 12 families have been identified as active or promising sources of phytochemicals with antiproliferative properties. The plant families, which cover all the species studied in this field, are Lamiaceae (7 species) and Asteraceae (4 species); the most studied species being Argania spinosa (Sapotaceae) and Arisarum vulgare (Araceae), Thymus Genus (Labiateae) and Peganum harmala (Zygophyllaceae). Based on the search results, it is recommended to increase the number of experimental studies and to begin conducting clinical trials with Moroccan plants and their active compounds selected by in vitro and in vivo activities.

Effects of Pinellia temata tuber on the emetic and sedative action of xylazine hydrochloride in cats (고양이에 대한 염산 Xylazine의 구토 및 진정작용에 미치는 반하의 영향)

  • Park, Joon-hyoung
    • Korean Journal of Veterinary Research
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    • v.32 no.3
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    • pp.341-345
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    • 1992
  • The tuber of Pinellia ternata Breitenbach(Araceae), which is distributed in Korea, China, and Japan, has been used in traditional Chinese medicine. The prescription containing Pinellia tuber shows anti-emetic, sedative, and anti-tussive effects. The purpose of this study was to investigate the effects of Pinellia ternata tuber on the xylazine-induced emetic and sedative responses in cats. The results were as follows ; 1. Intramuscular injection of xylazine hydrochloride(1.0mg/kg) reliably evoked vomiting with an incidence of 100% and sedated with a mean sedation time of 34.22 min. 2. The xylazine-induced emetic and sedative responses were not prevented by oral administration of powder (0.5g/head), decoction ($1.0m{\ell}/100g$), and methanol extract ($0.1m{\ell}/100g$) of the Pinellia ternata tuber. 3. The xylazine-induced emetic and sedative responses were inhibited by intravenous injection of decoction($0.3m{\ell}/100g$) of the Pinellia ternata tuber. 4. The xylazine-induced emetic and sedative responses were inhibited by intravenous injection of a combined mixture of yohimbine hydrochloride(0.125mg/kg) and 4-aminopyride(0.3mg/kg).

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