• 한국미생물·생명공학회지
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• 제48권4호
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• pp.399-422
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• 2020

도시화 및 산업화로 인해 발생된 중금속으로 오염된 토양의 정화는 인간의 건강 뿐 아니라 지구생태계의 지속성을 위해 매우 중요하다. 중금속 오염 토양 정화 기술 중 식물상복원법은 타 방법에 비해 처리 단가가 저렴하고, 토양 비옥도 및 생물 다양성이 영향을 덜 받는 환경친화적인 방법이다. 이러한 식물상복원법에 식물생장촉진세균(plant growth promoting bacteria, PGPB)을 도입하여 중금속 독성 하에서 식물 생장을 촉진하고 중금속 정화 효율을 향상시킬 수 있다. 본 논문에서는 주요 토양오염물인 중금속의 발생원, 미생물·식물·인간에 미치는 중금속 영향 및 PGPB의 식물생장촉진 기작을 정리하였다. 중금속 오염 토양 정화를 위하여 식물상복원에 PGPB의 활용에 관한 최근 10년 동안의 연구 동향을 분석하였다. 또한, PGPB의 실제 적용 시 중금속 제거 효율에 미치는 다양한 환경 인자와 PGPB의 접종 방법의 영향을 고찰하였다. PGPB 활용 식물상복원 기술의 혁신을 위해서는 실제 현장에서 PGPB의 거동과 식물-PGPB-자생미생물 사이의 상호작용에 대한 이해가 필요하다.

• 디지털융복합연구
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• 제19권3호
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• pp.387-399
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• 2021

복지국가들은 사회복지를 위해 과학기술을 적극적으로 활용하고자 다양한 시도를 하고 있으며, 이러한 맥락에서 복지테크놀로지는 노인, 장애인 등을 비롯하여 일반 시민들의 삶의 질을 높이는 방향으로 활용될 수 있다. 이러한 측면에서 본 연구에서는 사회복지현장의 사회복지사들이 복지테크놀로지에 대해 어떻게 인식하고 있는지, 그리고 사회복지 분야에 복지테크놀로지를 어떻게 적용할 수 있을지, 향후 발전전망은 어떠한지 등에 대한 인식을 살펴보고자 하였다. 2018년 1월 한 달 간, 서울, 경기지역 사회복지관에서 근무하는 13명의 사회복지사를 대상으로 초점집단인터뷰를 실시하여 자료를 수집하였고, 수집된 자료에 대해 주제분석을 실시하였다. 본 연구결과, '복지테크놀로지의 개념', '복지테크놀로지의 필요성', '복지테크놀로지의 활용현황', '복지테크놀로지의 향후 전망'이라는 4개의 범주 및 12개의 하위범주, 24개의 개념이 도출되었다. 본 연구결과를 토대로 사회복지현장에서의 복지테크놀로지 발전 및 활성화를 위한 논의 및 제언을 하였다.

• 한국IT서비스학회지
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• 제20권6호
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• pp.107-123
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• 2021

Recently, there have been a number of researchers in the field of education who are actively exploring the educational applications of Blockchain technology, even though it is still in its infancy. Some researchers have been investigating its application in educational administration to issue academic credentials' or maintain student records with distributed ledger, which is the basis of Blockchain technology. Whereas, others have been examining its application in redesigning learning systems that are being used in various contexts, including online learning and lifelong education. In that vein, this paper aims to discuss a liberal arts education system which will be supported by Blockchain-based 'smart contracts'. At present, active efforts are being made to innovate liberal arts education in Korea, centered around government-funded university innovation projects and there have been reports of great achievements. However, if the Blockchain technology is applied to innovating the liberal arts education, we will innovate not only the liberal arts education but also university education as a whole. In this paper, there are suggestions on how to build a learner-centered educational environment where a liberal arts education system is supported by Blockchain-based smart contracts. First of all, the current innovation in liberal arts education and its limitations are discussed, followed by ways in which Blockchain-based smart contracts can reframe the liberal arts education system. Last but not least, the paper addresses implications of the Blockchain technology applications in liberal arts education, along with their future prospects.

• Structural Engineering and Mechanics
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• 제81권6호
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• pp.665-675
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• 2022

The safety problems of giant hydraulic structures such as dams caused by terrorist attacks, earthquakes, and wars often have an important impact on a country's economy and people's livelihood. For the national defense department, timely and effective assessment of damage to or impending damage to dams and other structures is an important issue related to the safety of people's lives and property. In the field of damage assessment and vulnerability analysis, it is usually necessary to give the damage assessment results within a few minutes to determine the physical damage (crack length, crater size, etc.) and functional damage (decreased power generation capacity, dam stability descent, etc.), so that other defense and security departments can take corresponding measures to control potential other hazards. Although traditional numerical calculation methods can accurately calculate the crack length and crater size under certain combat conditions, it usually takes a long time and is not suitable for rapid damage assessment. In order to solve similar problems, this article combines simulation calculation methods with machine learning technology interdisciplinary. First, the common concrete gravity dam shape was selected as the simulation calculation object, and XFEM (Extended Finite Element Method) was used to simulate and calculate 19 cracks with different initial positions. Then, an LSTM (Long-Short Term Memory) machine learning model was established. 15 crack paths were selected as the training set and others were set for test. At last, the LSTM model was trained by the training set, and the prediction results on the crack path were compared with the test set. The results show that this method can be used to predict the crack propagation path rapidly and accurately. In general, this article explores the application of machine learning related technologies in the field of mechanics. It has broad application prospects in the fields of damage assessment and vulnerability analysis.

• 한국수학교육학회지시리즈A:수학교육
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• 제63권2호
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• pp.295-318
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• 2024

This narrative review explores the transformative potential of immersive virtual reality (IVR) in enhancing high school students' mathematics competence, viewed through the lens of the technological, pedagogical, and content knowledge (TPACK) framework. This review comprehensively illustrates how IVR technologies have not only fostered a deeper understanding and engagement with mathematical concepts but have also enhanced the practical application of these skills. Through the careful examination of seminal papers, this study carefully explores the integration of IVR in high school mathematics education. It highlights significant contributions of IVR in improving students' computational proficiency, problem-solving skills, and spatial visualization abilities. These enhancements are crucial for developing a robust mathematical understanding and aptitude, positioning students for success in an increasingly technology-driven educational landscape. This review emphasizes the pivotal role of teachers in facilitating IVR-based learning experiences. It points to the necessity for comprehensive teacher training and professional development to fully harness the educational potential of IVR technologies. Equipping educators with the right tools and knowledge is essential for maximizing the effectiveness of this innovative teaching approach. The findings also indicate that while IVR holds promising prospects for enriching mathematics education, more research is needed to elaborate on instructional integration approaches that effectively overcome existing barriers. This includes technological limitations, access issues, and the need for curriculum adjustments to accommodate new teaching methods. In conclusion, this review calls for continued exploration into the effective use of IVR in educational settings, aiming to inform future practices and contribute to the evolving landscape of educational technology. The potential of IVR to transform educational experiences offers a compelling avenue for research and application in the field of mathematics education.

• 한국환경복원기술학회지
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• 제4권1호
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• pp.80-89
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• 2001

The objective of this study was to introduce the current status and development strategy for the environmental restoration of stream side in Japan, and to consider the methodology which could be effectively applied to the environmental restoration of stream side in Korea. 1. We should establish a new paradigm of forest conservation and erosion control which can emphasize the restoration of the stream side ecosystem and reduce soil movement in the areas. Also, in the past, the objective of forest conservation and erosion control was to fix soil by constructing permanent structures. The direction of future forest conservation and erosion control needs to be new forest conservation and erosion control technology to prevent large scale soil movement but allow small scale soil movement to conserve sound ecosystem and biotic habitats. 2. In the past, the goal of forest conservation and erosion control planning was to fix the amount of soil movement by constructing permanent facilities. Forest conservation and erosion control planning in the future needs to change the techniques which could prevent soil movement from large scale of soil disasters, but allow soil movement effectively to a small and middle scale's soil movement. Also, it is considered to change erosion control dams from non passing type to passing type. 3. In the point of ecological conservation aspects, we should evaluate the effects of new forest conservation and erosion control methods which are emphasized on the restoration of the stream side ecosystem. Also, forest conservation and erosion control construction projects for restoring stream and river ecosystem should be planned for perfectly restorating their ecosystems by the way of sustainable maintenance and management. 4. The restoration direction of stream and river ecosystems needs to be restoring the diversity of small geographies such as waterway, shoal and puddles rather than flattening stream bed. And the restoration of the stream side ecosystem should provide continuity of the stream side environment which allows desirable biological habitats, and environmentally sound facilities to harmonize with the environment.

• 한국토양비료학회지
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• 제20권3호
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• pp.285-299
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• 1987

질소비료(窒素肥料)의 효율(效率)을 높임에 있어서 시용시기(施用時期)와 시비위치(施肥位置)는 두가지 중요(重要)한 기술적(技術的) 수단이다. 이 두 수단들 가운데 어떤 것이 더 중요(重要)하냐 하는 것은 시비량(施肥量)에 따라 다르다. 즉 시비량(施肥量)이 적을 때에는 분시회수(分施回數)를 늘림보다는 기비(基肥)를 어떤 위치(位置)에 시용(施用)하느냐가 중요(重要)하고, 시비량(施肥量)이 많을 때에는 시비위치(施肥位置) 못지않게 어떻게 분시(分施)하느냐도 중요(重要)하다. 대체(大體)로, 아직 열대지역(熱帶地域)의 농가(農家)에서는 시비량(施肥量)이 낮은 편이므로, 분시회수(分施回數)보다는 시비위치(施肥位置)를 적절하게 하는 것이 중요(重要)하다. 이제까지 얻어진 연구결과(硏究結果)들을 검토해 보면, 질소비료(窒素肥料)의 시비위치(施肥位置)에 있어서, 수도작(水稻作)에서는 심층시비(深層施肥)가 유효(有效)하고, 밭농사에 있어서는 토층중(土層中) 측조시비(側條施肥)가 유효(有效)하다는 결론(結論)을 도출(導出)할 수 있다. 그러나 수도작(水稻作)에 있어서의 심층시비(深層施肥)는 적절(適切)한 시비기(施肥機)가 사용(使用)되지 않는 한(限), 농가(農家)에서의 실천(實踐)이 특(特)히 어렵다. 밭농사의 경우 토층중(土層中) 측조시비(側條施肥)는 수도작(水稻作)에서의 심층시비(深層施肥)에 비(比)해 실천(實踐)하기가 비교적(比較的) 용이(容易)하다. 수도작(水稻作)에서 완전(完全)한 심층시비(深層施肥)가 곤란(困難)한 조건(條件)에서는 차선책(次善策)으로 전층시비(全層施肥)를 권장해 봄직하다. 금후(今後)의 연구방향(硏究方向)으로, 수도용(水稻用) 간이(簡易) 심층시비기(深層施肥機)의 개발(開發)과, 농민이 쓰기에 편(便)하고 효율(效率)이 높은, 그러면서도 생산(生産)이 까다롭지 않은 신질소비료(新窒素肥料)의 개발(開發)을 들수 있을 것이다.

• Journal of Microbiology and Biotechnology
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• 제26권1호
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• pp.1-8
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• 2016

The new movement towards green chemistry and renewable feedstocks makes microbial production of chemicals more competitive. Among the numerous chemicals, organic acids are more attractive targets for process development efforts in the renewable-based biorefinery industry. However, most of the production costs in microbial processes are higher than that in chemical processes, among which over 60% are generated by separation processes. Therefore, the research of separation and purification processes is important for a promising biorefinery industry. This review highlights the progress of recovery processes in the separation and purification of organic acids, including their advantages and disadvantages, current situation, and future prospects in terms of recovery yields and industrial application.

• 한국방사선학회논문지
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• 제8권3호
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• pp.123-136
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• 2014

본 논문에서는 분자영상을 분류하고 적용 분야와 미래를 예측해 보고자 하였다. 분자영상은 생체 내에서 분자수준과 세포수준에서 일어나는 변화를 영상화하는 것으로써 분자세포생물학과 첨단영상기술이 발전하여 접목된 새로운 분야이다. 분자영상은 형광, 생물발광, SPECT, PET, MRI, Ultrasound 등의 영상 기법들을 이용하여 유전자 치료 모니터링, 세포추적, 세포 치료 모니터링, 항체영상, 약제 개발, 분자 상호작용 영상, 근적외선 형광 물질을 이용한 암 형광 영상, Bacteria 를 이용한 종양 표적 영상, 치료효과 조기 평가, 치료 효과 예측 등에 적용되고 있다. 분자 영상의 미래는 분자세포 생물학, 유전학, 화학, 약학, 물리학, 전산학, 의공학, 핵의학, 영상의학, 임상의학 등 여러 학문 분야가 융합되어 상호협조와 공동연구를 통하여 발전해 나갈 것이다. 분자영상의 태동으로 미래의 의료의 모습은 질병의 조기진단과 개인 맞춤형 치료가 가능하게 될 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권11호
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• pp.4663-4670
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• 2014

Trichostatin A (TSA) is a histone deacetylase (HDAC) inhibitor. We here investigated its effects on proliferation and apoptosis of the CNE2 carcinoma cell line, and attempted to establish genome-wide DNA methylation alteration due to differentially histone acetylation status. After cells were treated by TSA, the inhibitory rate of cell proliferation was examined with a CCK8 kit, and cell apoptosis was determined by flow cytometry. Compared to control, TSA inhibited CNE2 cell growth and induced apoptosis. Furthermore, TSA was found to induce genome-wide methylation alteration as assessed by genome-wide methylation array. Overall DNA methylation level of cells treated with TSA was higher than in controls. Function and pathway analysis revealed that many genes with methylation alteration were involved in key biological roles, such as apoptosis and cell proliferation. Three genes (DAP3, HSPB1 and CLDN) were independently confirmed by quantitative real-time PCR. Finally, we conclude that TSA inhibits CNE2 cell growth and induces apoptosis in vitro involving genome-wide DNA methylation alteration, so that it has promising application prospects in treatment of NPC in vivo. Although many unreported hypermethylated/hypomethylated genes should be further analyzed and validated, the pointers to new biomarkers and therapeutic strategies in the treatment of NPC should be stressed.