• The Korea Journal of Herbology
• /
• v.32 no.6
• /
• pp.23-29
• /
• 2017

Objective : Hyperuricemia is a metabolic disease characterized by elevated blood uric acid levels, and its prevalence is rapidly increasing worldwide. Alpiniae Oxyphyllae Fructus (AO) belonging to Zingiberaceae is one of well-known traditional medicines in China and Korea, and has been used to treat intestinal disorders, urosis, diuresis, and chronic glomerulonephritis traditionally. However, the effect of AO has not been studied. In this study we investigated the anti-hyperuricemic effect of AO, and the mechanisms underlying the effect in potassium oxonate (PO)-induced hyperuricemic rats. Methods : To examine the anti-hyperuricemic effects of the AO extract, serum uric acid levels were analyzed in normal and PO-induced hyperuricemic rats. The mechanism underlying the effects of the AO extract on uric acid levels was studied through xanthine oxidase (XOD) activity test and uric acid uptake assay in vitro. The chemical finger printing of the AO extract was analyzed using HPLC-DAD. Results : The AO extract significantly reduced serum uric acid levels in normal as well as PO-induced hyperuricemic rats. It also significantly inhibited the uptake of uric acid in oocytyes and human embryonic kidney cells (HEK293) expressing urate transporter (URAT)1, but not XOD activity in vitro. The chemical finger printing analysis of the AO extract showed nootkatone as a main component. Conclusion : The AO extract exhibits anti-hyperuricemic effects, and these effect were accompanied by increasing excretion of uric acid in kidney. Therefore, the AO extract could be used for prevention or treatment of hyperuicemia and gout.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.23 no.3
• /
• pp.59-64
• /
• 2023

Fire and disaster broadcasting systems are divided into analog, digital, and network-based digital public address systems, and important specifications in network-based digital public address systems are low-latency audio, high sampling rate, and multi-channel input and output. In the past, it has been widely used to the AoE method for distinguishing based on the MAC address of the data link layer. However, this method has a problem of increasing complexity and cost. This proposal is an AoIP/UDP method, which allows communication to be easily distinguished by IP address without the need for a separate redundant network, so that the network can be freely used and configured, and cost can be reduced by reducing complexity. After implementing the AoIP/UDP method, the experimental results showed that the cost was improved with the equivalent performance with 2.66ms latency.

• The Bulletin of The Korean Astronomical Society
• /
• v.46 no.2
• /
• pp.53.3-53.3
• /
• 2021

Adaptive Optics (AO) was first studied in the field of astronomy, and its applications have been extended to the field of laser, microscopy, bio, medical, and free space laser communication. AO modelling and simulation are required throughout the system development process. It is necessary not only for proper design but also for performance verification after the final system is built. In KASI, we are trying to develop the AO Python Package for AO modelling and simulation. It includes modelling classes of atmosphere, telescope, Shack-Hartmann wavefront sensor, deformable mirror, which are the components for an AO system. It also includes the ability to simulate the entire AO system over time. It is being developed in the Super Eye Bridge project to develop a segmented mirror, an adaptive optics, and an emersion grating spectrograph, which are future telescope technologies. And it is planned to be used as a performance analysis system for several telescope projects in Korea.

• International journal of advanced smart convergence
• /
• v.6 no.2
• /
• pp.51-58
• /
• 2017

Recently, rapid advances of Ethernet and IP technology have brought many changes in the sound industry. In addition, due to AoIP-based audio transmission technology, various problems of the acoustic system (sound quality deterioration due to long distance transmission, complicated wiring) have improved dramatically. However, when many distributed audio systems are connected with AoIP equipment, if there is a problem in the equipment, it is impossible to operate the connected system. AoIP equipment only can transmit audio signals but cannot adjust the system for acoustic environment. In this paper, AoIP equipment is to be installed with sound equipment on a one-to-one basis, so that various existing problems can be solved and adjustment of sound quality (reverberation, echo, delay and EQ) can be possible by AoIP-based OAC (On-site Audio Center) with built-in DSP function. As a result, uncompressed real-time transmission by distributed transmission/receipt module in OAC (On-site Audio Center) and high quality sound by adjustment of sound quality with built-in DSP can be acquired. It is expected that OAC based sound system will be the industry standard in ubiquitous environment.

• Journal of Life Science
• /
• v.24 no.1
• /
• pp.61-66
• /
• 2014

The purpose of this study was to investigate the immunomodulatory effects of Alpina officinarum (AO) ethanol extract on immunocompromised mice. The mice were injected intraperitoneally with an immunosuppressive drug, cyclophosphamide, and then administrated orally with 30, 100, and 300 mg/kg of ethanol extract of AO (AO 30, AO 100, and AO 300, respectively). The concentrations of cytokines and immunoglobulins (IgM, IgA, IgG) in serum were measured. The body weight of the mice and spleen cell number of the AO-fed group showed no significant difference compared to a control group. The concentrations of several cytokines, including IL-2, IFN-${\gamma}$, and TGF-${\beta}$, in serum showed a significant increase in the AO 100 group compared to the control and other groups (p<0.05). The IL-4 level showed no significant difference in the experimental groups. The supplementation of AO (30, 100, 300 mg/kg) significantly increased the concentration of IgM (p<0.05). The concentration of IgA was significantly increased in the AO 100 group (p<0.05) compared to the control group. It can be concluded that AO ethanol extract enhances immune function by promoting the production of cytokines and immunoglobulins.

• The Korean Journal of Food And Nutrition
• /
• v.29 no.6
• /
• pp.938-945
• /
• 2016

This study was conducted to investigate the risk of chronic disease as predicted by abdominal obesity in Korean adult females. Data on 2,738 adult females aged 40~64 yrs was obtained from the 2013~2014 Korean National Health Nutrition Examination Survey. The subjects were divided into normal (n=1,835), abdominal obesity (AO, n=73), and BMI-diagnosed abdominal obesity (BMI-AO, n=505) groups based on the NCEP-ATP III guidelines and by applying the KSSO definition regarding waist circumference. Triglyceride blood levels, fasting blood sugar levels, systolic blood pressure, and diastolic blood pressure were higher in the AO and BMI-AO groups than in the normal group. The HDL-cholesterol levels of subjects in the two abdominal groups were lower as compared to those of subjects in the normal group. The mean adequacy ratio was lower among subjects in the AO and BMI-AO groups than among those in the normal group. Moreover, the NAR and INQ scores of some micro-nutrients in both of the abdominal obesity groups were lower than those in the normal group. Both the AO and BMI-AO groups showed significantly higher risks of hypertriglycemia, hyperglycemia, hypertension, hypoHDL-cholesterolemia, and metabolic syndrome than were shown by the normal group. Notably, as compared to the normal group, the AO group showed higher risk of hypercholesterolemia, hyperLDL-cholesterolemia, hypertriglycemia, and metabolic syndrome than did the BMI-AO group. This finding suggests that it is essential to develop prevention programs including programs for those with abdominal obesity despite their having a BMI within the normal range.

• Atmosphere
• /
• v.20 no.4
• /
• pp.387-398
• /
• 2010

This study shows that frequency of tropical cyclone (TC) around Korea in summer (June-September) has positive relation with Arctic Oscillation (AO) in the preceding April. In a positive AO phase, each of anomalous cyclone and anomalous anticyclone is developed in low latitude and middle latitude regions of East Asia from the preceding April to summer. As a result, while anomalous southeasterly around Korea serves as a steering flow that TCs move toward this area is strengthened, northwesterly that reinforced in southeastern area of East Asia plays a role in preventing TCs from moving toward this area. In addition, due to this distribution of pressure systems developed in this AO phase, TCs tend to occur, move and recurve in further northeastern region in the western North Pacific than TCs in a negative AO phase. On the contrary, TCs in a negative AO phase mainly move westward toward southern China or Indochina Peninsula from Philippines. Eventually, intensity of TCs is weaker than those in a positive AO phase due to the terrain effect caused by high passage frequency of TCs in mainland China.

• Journal of Nutrition and Health
• /
• v.39 no.7
• /
• pp.684-691
• /
• 2006

Abdominal obesity (AO) is a strong risk factor for type 2 diabetes and cardiovascular disease, which has shown a remarkable increase in Korea. This study aimed to identify prevalence of AO and related risk factors in Korean adults. A total of 5,132 men and women aged 20-85 years old from the 2001 Korean National Health and Nutrition Examination Survey were included in the analyses. AO was defined as waist circumference >=90 cm in men and >=85 cm in women as proposed by Korean Society of Obesity. Multiple logistic regression was carried out to identify risk factors for AO. Three models were specified: (i) demographic and socioeconomic factors (model 1: age, education, poverty income ratio, employment), (ii) lifestyle factors and covariates (model 2: physical activity, cigarette smoking, alcohol consumption, dietary quality, type 2 diabetes, co-morbidity) and (iii) demographic, socioeconomic and lifestyle factors (model 3). The prevalence of AO was 24.1 % in men, 23.5% in women. High poverty income ratio in men and low education attainment in women were risk factors for AO in model. 1. There was a significant association of AO with alcohol consumption, physical inactivity and dietary quality in men, alcohol consumption and cigarette smoking in women. These factors except alcohol consumption in men became insignificant in model 3. This findings underscore the importance of developing AO prevention programs in Korea that target the at risk groups identified in this study. A program focusing on low income men or less educated women would be more efficient.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.27 no.1
• /
• pp.131-134
• /
• 2023

The age of information (AoI) was proposed to quantify the freshness of information about the status of a remote source system, which is defined as the amount of time that has elapsed since a packet was created at its source. This paper analyzes the age of information of a discrete time Geo/D/1/1 status update system. For this purpose, the system is modeled as a discrete-time two-state Markov chain. The stationary probability distributions for peak AoI and AoI are obtained. The average peak AoI, the average AoI, and the freshness ratio of information are also derived. Some numerical results of the analysis are presented.

• Current Optics and Photonics
• /
• v.8 no.2
• /
• pp.183-191
• /
• 2024

High-resolution retinal imaging based on adaptive optics (AO) is important for early diagnosis related to retinal diseases. However, in practical applications, closed-loop AO correction takes a relatively long time, and traditional open-loop correction methods have low accuracy in correction, leading to unsatisfactory imaging results. In this paper, a SH-U-net-based open-loop AO wavefront correction method is presented for a retinal AO imaging system. The SH-U-net builds a mathematical model of the entire AO system through data training, and the Root mean square (RMS) of the distorted wavefront is 0.08λ after correction in the simulation. Furthermore, it has been validated in experiments. The method improves the accuracy of wavefront correction and shortens the correction time.