• Radiation Oncology Journal
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• v.33 no.2
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• pp.83-88
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• 2015

Purpose: To evaluate the appropriateness of prophylactic inguinal nodal irradiation (PINI), we analyzed patterns of failure in anal cancer patients who were inguinal node-negative at presentation and did not receive PINI. Materials and Methods: We retrospectively reviewed the records of 33 anal cancer patients treated by definitive concurrent chemoradiation therapy (CCRT) between 1994 and 2013. Radiotherapy consisted of a total dose of 44-45 Gy (22-25 fractions in 5 weeks) on the whole pelvis, anus, and perineum. Except inguinal lymphadenopathy was present at initial diagnosis, the entire inguinal chain was not included in the radiation field. In other words, there was no PINI. Results: The median follow-up duration was 50 months (range, 4 to 218 months). Median survival and progression-free survival (PFS) were 57 months (range, 10 to 218 months) and 50 months (range, 4 to 218 months), respectively. Among the survival, the median follow-up duration was 51 months (range, 12 to 218 months). The 5-year overall survival and PFS rates were 93.4% and 88.8%, respectively. Although none of the patients received inguinal node irradiation for prophylactic purposes, there was no inguinal recurrence. Conclusion: Treatment of anal cancer by omitting PINI might be considered in selected patients with clinically uninvolved inguinal nodes.

• Animal Systematics, Evolution and Diversity
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• v.32 no.1
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• pp.28-37
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• 2016

We describe the morphological characteristics of two morids, Gadella jordani and Physiculus japonicus, belonging to the order Gadiformes, based on Korean specimens collected from the Korean ocean. Two specimens of Gadella jordani was first collected from Jeju Island, Korea and the East Sea, Korea, in 2013-2014. This species is characterized by 8, 67-69 dorsal fin rays, 66-71 anal fin rays, 5+13 gill rakers, no barbel on the lower jaw, no vomerine teeth, and a ventral luminous organ closer to the anus than to the interventral line. We described it as the first record to the Korean fish fauna, and proposed the new Korean name "Min-su-yeom-dae-gu-sok" for the genus Gadella, and "Min-su-yeom-dae-gu" for the species G. jordani. Physiculus japonicus was first reported by Koh and Moon in the year 1999 based on a single specimen in Korea. However, no study has been attempted to describe the morphological characteristics in Korea since then. In 2013-2014, three specimens of P. japonicus was collected from Jeju Island, Korea and the East Sea, Korea, and we redescribe P. japonicus in detail. This species is characterized by 9-10, 63-64 dorsal fin rays, 70-73 anal fin rays, 3+7-8 gill rakers, a short barbel on the lower jaw, and a ventral luminous organ equidistant between the interventral line and the anus.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.36 no.2
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• pp.136-143
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• 2003

The eggs of Favonigobius gymnauchen attached on the under side of a small stone were collected off Seongsan-eup Cheju-do in August, 2000 to investigate their development of egg, larvae and juveniles. The fertilized eggs were elliptical in shape (mean long axis: 1.50 mm; mean short axis: 0.57 mm) and transparent. There were filaments on one side of the egg membrane. Larvae hatched at 48 hrs 50 mins after morula stage with 25-26 myotomes in $22.8-28.5^{\circ}C\;(mean\;24.7^{\circ}C).$ The newly hatched larvae were 2.31-2.49 mm (mean 2.37 mm n=10) in total length (TL) and their mouth and anus were already opened. Their melanophores were appeared on the over gas globule, around anus and the part of caudal peduncle with 24-25 myotomes. At 4-5 days after hatching. larvae attained 3.81-4.07 mm (mean 3.96 mm, n=10) in TL and their yolk sac was completely absorbed. They began to eat rotifer and transformed to postlarvae stage. At 14 days after hatching, postlarvae attained 6.17-6.31 mm (mean 6.21 mm, n=10) in TL and their caudal notocord was flexed $45^{\circ}$ upward. At 24 days after hatching, postlarvae attained 8.69-9.10 mm (mean 8.87 mm, n=10) in TL had reached the juvenile stage. All fins were formed with the complete set of fin rays with the following counts: dorsal fin rays IV-I, 9-10; anal fin rays I, 9; pectoral fin rays 17; ventral fin rays: I, 5; caudal fin rays: 9+8= 17.

• Fisheries and Aquatic Sciences
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• v.14 no.4
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• pp.403-410
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• 2011

Scartelaos gigas is an amphibious mudskipper species that inhabits mud flats in Korea, China, and Taiwan. This fish is at risk of extinction because of its very restricted habitat and overexploitation. Information about this fish's reproductive characteristics is needed for species conservation. The sexual maturity and early life history of S. gigas were investigated through histological methods and direct observation of eggs in the wild, respectively. In total, 560 individuals of S. gigas were collected with the aid of fishermen from March 2003 to October 2003 at Jung-do Island, southwest Korea. Through microscopic observations of gonadal development, it was determined that S. gigas of both sexes were immature in April, but began to reach maturity in May, and were then fully mature by June, which was maintained until July. In August, some female fish developed early oocytes, but by September oocytes were observed to have degenerated and had been absorbed. Spawned eggs were elliptical and had an average size of 1.37 mm (long axis) by 0.69 mm (short axis). The newly hatched larvae (3.03 mm total length, TL) had an open mouth and anus, two melanophores near the anus, and one large melanophore between the 18th and 19th myomeres. The larvae (3.18 mm TL) showed absorption of the yolk and oil globule within 5 days after hatching and became prelarvae. This species should be considered vulnerable or conservation-dependent, and thus parental fish need to be protected from fishermen during the main spawning season (June).

• Development and Reproduction
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• v.18 no.1
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• pp.13-23
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• 2014

This study is conducted to monitor the morphological developmental features of the egg development, larvae and juvenile of Epinephelus septemfasciatus, the fertilized eggs were gotton using artificial insemination. Matured parents are collected from marine caged fish farms in Geomun-ri, Samsan-myeon, Yeosu-si, Jeollanamdo Korea in June 2012. The fertilized eggs were pelagic eggs containing one oil globule, and measured 0.81~0.89 mm ($0.85{\pm}0.04mm$, n=50) in diameter. In regard to rearing environment, the water temperature is $21.0{\sim}23.0^{\circ}C$ and the salinity is 32.0~33.2‰. Hatching was observed from 48 hours after fertilization, the mouth and anus of prelarvae was not opened but had egg yolk at newly hatched. 4 days after hatching, the mouth and anus of postlarvae was opened and began to eat Rotifer and was measured 2.40~2.49 mm ($2.45{\pm}0.03mm$ n=10) in total length. 12 days after hatching, postlarvae was measured 3.77~4.67 mm ($4.27{\pm}0.33mm$) in total length, its the second pole tide of dorsal fin and the first pole tide of pelvic fin was extended longitudinally. 71 days after hatching, juvenile was measured 40.5~45.4 mm ($42.6{\pm}2.04mm$) in total length. Seven bands were observed in body, and pole tides of dorsal and pelvic fins were shortened.

• Journal of Genetic Medicine
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• v.12 no.1
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• pp.44-48
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• 2015

Townes-Brocks syndrome (TBS) is a rare genetic disorder characterized by the classic triad of congenital anomalies of the anus, thumbs, and ears, with variable expressivity. Additionally, renal malformations, cardiac anomalies, and endocrine and eye abnormalities can accompany TBS, although less frequently. TBS is inherited in an autosomal dominant fashion; however, about 50% of patients have a family history of TBS and the remaining 50% have de novo mutations. SALL1, located on chromosome 16q12.1, is the only causative gene of TBS. SALL1 acts as a transcription factor and may play an important role in inducing the anomalies during embryogenesis. Clinical features of TBS overlap with those of other multiple anomaly syndromes, such as VACTERL syndrome, Baller-Gerold syndrome, Goldenhar syndrome, cat eye syndrome, and Holt-Oram syndrome. Consequently, there are some difficulties in differential diagnosis based on clinical manifestations. Herein, we report a Korean family with two generations of TBS that was diagnosed based on physical examination findings and medical history. Although the same mutation in SALL1 was identified in both the mother and the son, they displayed different clinical manifestations, suggesting a phenotypic diversity of TBS.

• Korean Journal of Ichthyology
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• v.8 no.2
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• pp.23-32
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• 1996

External morphology of three species of damselfishes, Chromis notata, C. analis and C. fumea were studied based on the samples collected from the Korean waters from 1993 to 1994. In morphology of the black spot at base of pectoral fins, C. notata has a large triangluar spot at Cheju population and a small circular spot at Sin - am. In the length of pelvic fin, C. notata of Korea can be classified into 3 groups. First group has a pelvic fin that extends to the origin of anal fin, second extends to the anus, third not extend to the anus. C. analis has higher body depth than C. notata and C. fumea in % of standard length. C. fumea has a minute serrate preopercle and no black spot at base of pectoral fins. In distribution, C. notata has a more widly distriubtion area than C. analis and C. fumea. Therefore, C. notata has more tolerance of cold waters than C. analis and C. fumea.

• Korean Journal of Ichthyology
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• v.20 no.4
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• pp.318-323
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• 2008

A single specimen of the ophichthid Muraenichthys gymnopterus (254.6 mm TL) was collected from the middle Yellow Sea off Incheon, Korea. It represents the first record of the species, the genus, and the subfamily from Korea. This species is characterized by the following combination of characters: a constricted midlateral gill opening; dorsal fin origin before anus, closer to the anus than to the gill opening; blunt teeth, jaw teeth in bands, and multiserial dentition; third preopercular pore present; single infraorbital pore between anterior and posterior nostrils; brownish colour; depth and width of gill opening 43.2 times and 33.7~65.3 times in total length, respectively; eye diameter 15.0~31.0 times in head length and total vertebrae 154~161. New Korean names are proposed, "Gaet-mul-baem-a-gwa" for the subfamily Myrophinae, "Gaet-mul-baem-sok" for the genus Muraenichthys, and "Gaet-mul-baem" for M. gymnopterus.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.54 no.2
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• pp.188-193
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• 2021

On March 13, 2018 two postflexion larval specimens (18.28 mm and 16.80 mm in standard length) belonging to the family Cryptacanthodidae, suborder Zoarcoidei were collected from Sokcho and Gangneung in Gangwon Province. The family Cryptacanthodidae comprises 4 species worldwide: 3 in the North Pacific Ocean and 1 in the western North Atlantic Ocean. As a result of analyzing 620 bp of the mtDNA COI region, the two postflexion larvae collected in this study were identified as Cryptacanthodes bergi by 99.5% agreement with C. bergi adult registered in NCBI. Postflexion larvae of C. bergi are compressed with large eyes and radial pectoral fins and the anus located in front of the center of the body. Melanophores were intensively distributed along the dorsal midline, except for caudal peduncle, and sporadically distributed on the back of the anus. In addition, there were limited star-like melanophores on the back of the gut. This species showed 0.058 genetic distance when compared mtDNA COI region of C. aleutensis, and it was well distinguished in the distribution pattern of black vesicles of the head, count and measurement traits. Considering the morphological and ecological characteristics of this species, we suggest a new Korean name, " Gwisin-jang-gaeng-i ".

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.20 no.3
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• pp.194-197
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• 2017

Alimentary tract duplication cysts are rare congenital anomalies, most commonly located in the ileum, but may present anywhere from mouth to anus.Clinically, they may be asymptomatic, incidentally diagnosed or may present with obstruction, volvulus, intussusception or gastrointestinal bleed. Here we report a case of a one year old male child presenting in gasping state and shock. Despite the initial strong suspicion of Meckel's diverticulum and tubercular abdomen, the final diagnosis remained elusive till exploratory laparotomy was performed which revealed a duplication cyst of ileum with perforation into the umbilicus. Duplication cyst should always be kept as a differential diagnosis so that early intervention can help in better management.