• 대한예방한의학회지
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• 제10권2호
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• pp.131-145
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• 2006

Perilla frutescens is known as the herb helps digestion, tonifies stomachache, and decreases fever in oriental medicine. And it is reported it possess the anti-pyretic effect, anti-inflammatory effect, anti-allergy effect, anti-tumor effect etc. The components isolated from this herb consist of perilla aldehyde, d-limonene, ${\alpha}-pinene$, cyanin, linoleic acid, palmitic acid, menthol, rosmarinic acid and luteolin etc. But there is no effective tools to determine the quality of this herb. In this study, we aimed to analyze the changes of liquid chromatogram pattern, one of major standardization method, to determine the quality of Perilla frutescens.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1995년도 추계학술대회 논문집
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• pp.559-562
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• 1995

In the crane control system, it is reguired that the travelling time of the crane must be reduced as much as possible and the swing must be stoped at the end point. In paper, we present a hybrid control method which include the optimal regulator and velocity pattern controller in order to make high performance of the anti-sway. To implement the control algorithm, the dynamic equation is linearlized at an equilibrium point, so that the liner time invariant state equation can be obtained. In order to experiment the crane control, we consider 1 over 10 of the gantry crane which is used in a port. As a result, the hybrid control method improve efficient anti-sway control more than conventional velocity pattern control. It is expected that the proposed system will make an important contribution to the industrial fields.

• Journal of Positioning, Navigation, and Timing
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• 제5권3호
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• pp.131-136
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• 2016

The present paper shows that beamforming algorithm such as Minimum Variance Distortionless Response (MVDR) based on array antenna signal processing can have not only anti-jamming but also anti-spoofing characteristics. A beam pattern due to the beamforming algorithm strengthens received signal power as it is formed in the incident direction of desired signal. During the process, the effect of unnecessary signals such as spoofing signals can be reduced because the beam pattern reduces received signal power in the incident directions excluding the beam pattern-directed direction. In order to analyze the anti-spoofing effect due to the beamforming algorithm, a software-based simulation environment was configured. An arbitrary error was applied between incident direction of Global Positioning System (GPS) satellite signal and steering vector direction of the beamforming algorithm to analyze the received signal power and required conditions were provided to see the anti-spoofing effect due to the beamforming algorithm. The used antenna was 7-element planar circular array and beam patterns were formed through the MVDR algorithm.

• 한국군사과학기술학회지
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• 제12권1호
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• pp.18-23
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• 2009

It is hard to find an operation case using anti-submarine searching pattern(ASSP) developed by Korean navy since Korean navy has begun submarine searching operation. This paper proposes the method to develop hull mount sonar(HMS) based optimal submarine searching pattern by using genetic algorithm. Developing the efficient ASSP based on theory in near sea environment has been demanded for a long time. Submarine searching operation can be executed by using ma ulti-step and multi-layed method. however, In this paper, we propose only HMS based ASSP generation method considering the ocean environment and submarine searching tactics as a step of first research. The genetic algorithm, known as a global opination method, optimizes the parameters affecting efficiency of submarine searching operation. Finally, we confirm the performance of the proposed ASSP by simulation.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.283-284
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• 2019

In the last decades patient's suffering with Parkinson's disease is increasing at a rapid rate and as per prediction it will grow more rapidly as old age population is increasing at a rapid rate through out the world. As the performance of wearable sensor based approach reached to a new height as well as powerful machine learning technique provides more accurate result these combination has been widely used for assessment of various neurological diseases. ON state is the state where the effect of medicine is present and OFF state the effect of medicine is reduced or not present at all. Classification of ON/OFF state for the Parkinson's disease is important because the patients could injure them self due to freezing of gait and gait related problems in the OFF state. in this paper wearable sensor based approach has been used to collect the data in ON and OFF state and machine learning techniques are used to automate the classification based on the gait pattern. Supervised machine learning techniques able to provide 97.6% accuracy while classifying the ON/OFF state.

• Journal of Preventive Medicine and Public Health
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• 제17권1호
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• pp.203-210
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• 1984

Primary screening test for serum HBsAg by RPHA from 4,805 persons who were clinically well through preemployment examination for the period of one calendar year of 1983 revealed 476 (9.9%) positive individual carriers. There were no significant differences in distribution of positives of serum HBsAg by age group, profession, or province area. Among positives of serum HBsAg, 356 (74.8%) showed normal findings and 120 (25.2%) showed abnormal findings in liver function test, respectively. Radioimmunoassay was done in 169 positives of HBsAg and RIA detected 10 negative persons who were positive by RPHA revealing 5.9% of false positive rate and 94.1% of sensitivity of RPHA. In RIA profile of HBV markers, pattern I (HBsAg+, Anti-HBe+) was 46.6%, pattern II (HBsAg+, HBeAg+) was 33.3%, pattern III (HBsAg+only) was 18.3%, pattern IV (HBsAg+, HBeAg+, Anti-HBs+) was 1.3%, pattern V (HBsAg+, HBeAg+, Anti-HBe+) was 0.6%, respectively. There were no positives of HBsAg among 10 persons who were negatives of HBsAg by RIA.

• 대한기계학회논문집A
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• 제27권10호
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• pp.1615-1622
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• 2003

Being contacted directly with. ground, the tire tread part is in shape of complex patterns of variable ASDs(anti-skid depth) to satisfy various tire performances. However, owing to the painstaking mesh generation job and the extremely long CPU-time, conventional 3-D tire analyses have been performed by either neglecting tread pattern or modeling circumferential grooves only. As a result, such simplified analysis models lead to considerably poor numerical expectations. This paper addresses the development of a 3-D tire mesh generation considering the detailed tread pattern and shows that the contact pressure and frictional energy distribution of tires considering the detailed pattern become better than those by the simplified tire model.

• IMMUNE NETWORK
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• 제20권1호
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• pp.8.1-8.15
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• 2020

Immune checkpoint blockade targeting PD-1 and PD-L1 has resulted in unprecedented clinical benefit for cancer patients. Anti-PD-1/PD-L1 therapy has become the standard treatment for diverse cancer types as monotherapy or in combination with other anticancer therapies, and its indications are expanding. However, many patients do not benefit from anti-PD-1/PD-L1 therapy due to primary and/or acquired resistance, which is a major obstacle to broadening the clinical applicability of anti-PD-1/PD-L1 therapy. In addition, hyperprogressive disease, an acceleration of tumor growth following anti-PD-1/PD-L1 therapy, has been proposed as a new response pattern associated with deleterious prognosis. Anti-PD-1/PD-L1 therapy can also cause a unique pattern of adverse events termed immune-related adverse events, sometimes leading to treatment discontinuation and fatal outcomes. Investigations have been carried out to predict and monitor treatment outcomes using peripheral blood as an alternative to tissue biopsy. This review summarizes recent studies utilizing peripheral blood immune cells to predict various outcomes in cancer patients treated with anti-PD-1/PD-L1 therapy.

• 동력기계공학회지
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• 제2권1호
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• pp.67-72
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• 1998

In crane control system, it is required that the travelling time of crane must be reduced as much as possible and there is no the swing of load at the end and starting points. In this paper, we present a hybrid control method which includes two control methods of the optimal regulator and the velocity pattern control in order to realize high performance of the anti-sway. To implement the control algorithm, the dynamic equation is linearlized at an equilibrium point, so that the linear time invariant state equation can be obtained. A 1/10 sized model crane of the usual gantry cranes is made and used to show the applicability of the developed hybrid control method. The effectiveness of developed hybrid control method is proved by experimental results which show us good performance for anti-sway control comparing to conventional velocity pattern control. Practically, it is expected that the proposed control system will make an important contribution to the automatic crane control system of the industrial fields.

• 한국위성정보통신학회논문지
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• 제10권4호
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• pp.46-51
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• 2015

본 논문에서는 항재밍 GPS(Global Positioning System) 시스템을 위한 선형 어레이 안테나(linear array antenna) 시뮬레이터(simulator)를 설계하고 시뮬레이션을 통해 다양한 성능 평가를 수행하였다. 먼저 GPS 위성의 신호 구조 분석을 통해 모의 송신신호를 발생시키고, 선형 어레이 안테나 고려시 잡음 환경하에서의 어레이 수에 따른 SNR(Signal to Noise power Ratio) 성능을 분석하였다. 또한 MMSE(Minimum Mean Square Error) 방식의 신호처리 시스템을 통해 재머(jammer) 수에 따른 항재밍 빔패턴(beam pattern) 성능을 분석하였으며, 안테나 칼리브레이션(calibration) 문제를 고려하여 어레이간 지연이 존재하는 경우에서의 항재밍 성능을 분석하였다.