• Journal of Embryo Transfer
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• v.29 no.2
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• pp.171-175
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• 2014

This study was conducted to determine the efficacy of anthelmintics against gastrointestinal parasitic infestation in periparturient dairy cows and its effect on milk yield and quality. Sixty pregnant cows of 1st & 2nd parity were divided into four groups. The efficacy of anthelmintic treatment was evaluated by counting faecal egg per gram (EPG) compared with pre-treatment values. The milk yield of each cow was recorded in pre and post treatment lactations. Cows of group A were treated with Nitroxynil 10 mg/kg body weight subcutaneously 30 days before parturition, group B were treated with combination of triclabendazole and levamisole 19.5 mg/kg body weight orally at calving and group C treated with $Endex^{(R)}$ at calving and 42 days after. The mean change in EPG 14 days after treatment was significantly higher (p<0.05) in treated (79.1%) cows than control. Average milk yield of group C ($2.8{\pm}0.8$) was significantly higher (p<0.01) than group A ($2.6{\pm}0.7$). Similarly, the average milk yield in all the treated cows was significantly (p<0.01) higher in treated lactation ($2.5{\pm}0.7$) than in the previous lactation ($2.2{\pm}0.7$). The average milk yield in all treated cows was significantly (p<0.01) higher than the control cows. Although, milk yields were higher in second parity than the first, there was no significant difference (p>0.05). The milk protein percentage was significantly higher (p<0.05) in treated group than the control group. Therefore, it may be concluded that periparturient anthelmintic treatment effectively reduced the gastrointestinal parasitic load and improved milk yield.

• Herbal Formula Science
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• v.7 no.1
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• pp.65-76
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• 1999

According to the study of literature on RADIX STEMONAE about its efficacy, pharmacological action, and clinical adaptive disease, the results are as follows; 1. About the efficacy of RADIX STEMONAE, it is known as moistening the lungs to arrest cough, and intestinal parasites from ancient to now, and dispelling phlegm is also known. 2. The clinical adaptation of RADIX STEMONAE is chronic bronchitis, pertussis, pulmonary tuberculosis in respiratory disease, and ascaricide for Ascaris, Enterobius vermicularis or eczema, pruritus, destroy louse for endermic liniment. 3. The pharmacological action of RADIX STEMONAE are antitussive, tuberculostatic, anthelmintic, antibacterial, antivirus, antifungal. 4. The antitussive mechanism of RADIX STEMONAE is central inhibitor for cough center of medulla oblongata, and the mechanisms of bronchial smooth muscle relax, and expectorant is also known.

• Journal of the korean veterinary medical association
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• v.20 no.5
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• pp.309-313
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• 1984

A total of 290 cattle in several districts was selected for treatment against the liver flukes, paramphistomes, and the gastrointestinal roundworms from March to september, 1983. 1. Egg reduction rates against the liver flukes, paramphistomes, and gastroi

• Parasites, Hosts and Diseases
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• v.57 no.3
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• pp.243-248
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• 2019

The purpose of this study was 2-fold: 1) to investigate the prevalence of gastrointestinal parasite infection in cats reared in Daegu, Republic of Korea and 2) to assess the efficacy and safety of a topical emodepside/praziquantel formulation for cats with parasitic infections. The gastrointestinal parasite infections were examined microscopically using the flotation method. Of 407 cats, 162 (39.8%) were infected by at least one gastrointestinal parasite, including Toxocara cati (63.0%), Toxascaris leonina (31.5%), Taenia taeniaeformis (3.7%), and Cystoisospora felis (1.9%). None of the infected animals had multiple infections. When the data were analyzed according to sex, age, and type of cat, stray cats showed statistically higher prevalence than companion cats (P<0.05). On the 5th day after treatment, no parasitic eggs were detected using microscopic examination. In addition, no adverse effects, such as abnormal behaviors and clinical symptoms, were observed in the cats treated with the drug. These results quantify the prevalence of gastrointestinal parasites in cats in Daegu, Republic of Korea, and show that topical emodepside/praziquantel is a safe and effective choice for treating the parasitic infections in cats.

• Korean Journal of Veterinary Service
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• v.15 no.1
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• pp.17-25
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• 1992

For evaluation on effects guiding fasciola prevention of which the specimens collected from 6,011 cows rears at 387 farms in inchon were tested to egg count examination for 4 years(1987-1990), and the questionnaire checked up 181 dairy farms for 2 years (1989-1990). The results were summarized as follows. 1. A yearly variation of fasciola infection rate above 31% were 83% In 1987, 58% in 1988, 25% in 1989, noninfection in 1990. 2. The average concentration in feces of infected dairy cattle was 79.4% below 1-10 eggs for 4 years(1987-1990) 3. In the results of the questionnaire for 2 years(1989-1990) the farmers gradually took interest in fasciola prevention. 4. To re-dose anthelmintics was 75.4% in 1989 and 82.5% in 1990 after 5∼7 months from previous dosage.

• Korean Journal of Veterinary Research
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• v.38 no.3
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• pp.589-594
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• 1998

The in vitro screening tests against the in vitro cultivated $L_3$ of Ascaris suum (in vitro $L_3$), which were cultivated from the embryonated egg to third-stage larva on 7 days in culture(DIC) and the in vivo rat's lung-derived $L_3$ of Ascaris suum (in vivo $L_3$), which were recovered from the lungs of rat on 7 days after infection, carried out in order to compare the anthelmintic efficacy of in vitro $L_3$ and that of in vivo $L_3$ in RPMI medium 1640 with 5% bovine calf serum. And also a screening test of efficacy against adult worms of Trichuris suis performed. The efficacies of screening tests were as follows : 1. The screening efficacies of abamectin and ivermectin against the in vitro $L_3$ were all 100% at the 10ppm concentration in RPMI medium 1640 on 5 DIC. 2. The screening efficacies of abamectin and ivermectin against the in vivo $L_3$ were all 100% at the 20ppm on 5 DIC or at 40ppm on 3 DIC. 3. The screening efficacies of abamectin and ivermectin against the adult worms of Trichuris suis were all 100% at 20ppm on 4 DIC. And therefore, the in vitro cultivated $L_3$ of Ascaris suum were used in the screening test as well as the in vivo rat's lung-derived $L_3$ of Ascaris suum. And also the adult worms such as Trichuris suis and filaroids which is small size and difficult to cultivate to vitro, were used in the screening test in vitro.

• Korean Journal of Veterinary Research
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• v.8 no.1
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• pp.11-17
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• 1968

Oral and subcutaneous administration of Tetramisole (d1-2, 3, 5, 6-tetrahydro-6-phenyl-imidazo- 2, 1-b thiazole hydrochloride) was effective in controlling the adult and immature forms of Metastrongylus apri in pigs when administered at the dose of 10-12.5 mg per kg of body weight.

• Natural Product Sciences
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• v.9 no.4
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• pp.286-290
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• 2003

Ratanjot is attributed to eight species of Boraginacae species belonging to genera Alkanna, Arnebia, Maharanga and Onosma and regarded as one of the important herbal drugs of indigenous systems of medicine. The root and root stock, which form the actual drug, are considered to be an anthelmintic, antipyretic and antiseptic. They are also claimed to be useful in burn, eczema, wounds and eruptions, and used for treating the diseases of eyes, bronchitis, abdominal pains, itch, etc. Several workers reported that the Naphthaquinones (arnebins), the main active constituents of the drug, are responsible for its colour and therapeutic efficacy. It is claimed that the Arnebia nobilis was imported to India from Afghanistan but the red coloured roots resembling with A. nobilis were found to be gathered by local people for commercial purposes during the course of botanical surey of Himalayan region. Hence, it is decided to evaluate Arnebia nobilis pharmacognostically. The important macro-microscopic features of this species are roots 1-5 cm broad; outermost xylem with broad vessels and innermost with groups of radially arranged narrow vessels while the middle region occupied by alternate rings of clusters of broad and narrow vessels and presence of pith. Besides the percentage of arnebin-1, -3 and 4 are 9.37, 10.53 and 1.72 respectively.