Background: A Comprehensive Aortic Root and Valve Reconstruction (CARVAR) procedure is comprised of aortic root wall reconstruction and corrections of the leaflets for treating various aortic valve diseases. We evaluated our recent early clinical experience with the CARVAR procedure. Material and Method: From October 2007 to September 2008, 114 cases (66 males) of CARVAR procedures were performed, The mean patient age was 53 years (range: 14~84) The patients were divided into 4 groups: 1) the AAR group: aortic regurgitation with aortic root wall deformity such as annulo-aortic ectasia or ascending aortic aneurysm (n=18), 2) the IAR group: isolated AR with leaflet abnormality (n=42), 3) the IAS group: isolated aortic stenosis (n=51) and 4) the PAVR group: previous aortic valve replacement (n=3). Sinotubular junction (STJ) reduction was done in all the patients, leaflet correction was done in 10 of the AAR group patients and in all the patients of the other groups, annulus reduction was done in 14 of the MR group patients and in 6 of the IAR group patients. Aortic dissection was excluded from this analysis. Result: There was no mortality or follow-up death. The diameter of the aortic sinus decreased from $54.6{\pm}8.4$ mm to $38.3{\pm}3.8$ mm in the AAR group, the mean AR grade decreased from 3.2 to 0.2 in the IAR group, the mean aortic valve pressure gradient decreased from $47.1{\pm}24.4$ mmHg to $15.1{\pm}11.7$ mmHg in the IAS group and the mean AR grade decreased to 0 in the PAVR group. Balloon type coronary perfusion cannula-related coronary ostial stenosis developed in 4 patients and this was treated with OPCAB in three patients and with PTCA in one patient. Two patients developed postoperative infectious endocarditis. All the patients were discharged and followed up in a stable condition. Conclusion: The CARVAR procedure showed excellent short term results, but a good further follow up result is required to apply this procedure to most kinds of aortic valve diseases.
Jo, Yeonguk;Song, Yoonho;Park, Sehyeok;Kim, Myung Sun;Park, In-Hwa;Lee, Changhyun
Tunnel and Underground Space
/
v.32
no.5
/
pp.285-297
/
2022
We report results of Extended Leak-Off Test (XLOT) conducted in a large diameter borehole, which is drilled for installation of deep borehole geophysical monitoring system to monitor micro-earthquakes and fault behavior of major fault zones in the southeastern Korean Peninsula. The borehole was planned to secure a final diameter of 200 mm (or more) at a depth of ~1 km, with 12" diameter wellbore to intermediate depths, and 7-7/8" (~200 mm) to the bottom hole depth. We drilled first the 12" borehole to approximately 504 m deep and installed American Petroleum Institute standard 8-5/8" casing, then annulus between the casing and bedrock was fully cemented. XLOT was carried out for several purposes such as confirming casing and cementing integrity, measuring rock stress states. To that end, we drilled additional 4 m long open hole interval to directly inject water and pressurize into the rock mass using the upper API casings. During the XLOT, flow rates and interval pressures were recorded in real time. Based on the logs we tried to analyze hydraulic conductivity of the test interval.
Kim Jin-Sun;Choi Jin-Ho;Yang Ji-Hyuk;Park Pyo-Won;Youm Wook;Jun Tae-Gook
Journal of Chest Surgery
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v.39
no.8
s.265
/
pp.588-597
/
2006
Background: The surgical repair of a tetralogy of Fallot (TOF) has been performed successfully with a favorable early and late outcome. However, the later development of pulmonary regurgitation and stenosis remains a problem. The development of pulmonary regurgitation and stenosis may be changed by the size of right ventricular outflow tract (RVOT) reconstruction at the initial total correction. Hence, it is necessary to investigate the ideal size of RVOT reconstruction. Material and Method: This prospective study was carried out to determine how a surgical strategy and the RVOT size affect the occurrence of pulmonary regurgitation and stenosis. From January 2002 to December 2004, 62 patients underwent the TOF total correction. The RVOT size (diameter of pulmonary valve annulus) of each case was measured after the RVOT reconstruction and converted to a Z value. A pre-scheduled follow up (at discharge, 6 months, 1 year, 2 years and 3 years) was carried out by echocardiography to evaluate the level of pulmonary regurgitation and stenosis. Result: The patients were divided to two groups (transannular group n=12, nontransannular group n=50) according to the method of a RVOT reconstruction. The Z value of RVOT=iameter of pulmonary valve annulus) (transannular group -1, $range\;-3.6{\sim}-0.8;$ nontransannular group -2.1, $range\;-5.2{\sim}-1.5)$ and the average pRV/LV after surgery ${(transannular group 0.44{\pm}0.09,\;nontransannular group\;0.42{\pm}0.09)}$ did not show any significant difference between two groups. The occurrence of pulmonary regurgitation above a moderate degree was more frequent in the transannular group (p<0.01). In nontransannular group, the development of pulmonary regurgitation more than moderate degree occurred to the patients with larger RVOT size (Z value>0, p<0.02) and the progressing pulmonary stenosis more than mild to moderate degree developed in the patients with smaller RVOT size (Z value<-1.5, p<0.05). A moderate degree of pulmonary stenosis developed for 4 nontransannular patients. Three underwent additional surgery and one underwent a balloon valvuloplasty. Their Z value of RVOT were -3.8, -3.8 -2.9, -1.8, respectively. Conclusion: When carring out a TOF total correction, transannular RVOT reconstruction group has significantly more pulmonary regurgitation. In the nontransannular RVOT reconstruction. the size of the RVOT should be maintained from Z value -1.5 to 0. If the Z value is less than -1.5, we should follow up carefully for the possibility of pulmonary stenosis.
Regarding the formula for measuring the area of a circle, the Archimedes' constant is generally written in front of the square of radius length, but there were a few cases where the Archimedes' constant was written after that in Germany and France. In this study, two things are studied: First, how many students are writing the Archimedes' constant after that? Second, what do the students think about the written order of characters in the formula for measuring the area of a circle? In the online survey of 201 people aged 14 to 21 in Korea, there was a perception of more than 86% that both are possible or only after that are possible. In this study, it is suggested that there is a difference between the general written order of characters and the natural perception of students formed through school education. In addition, students aged 14 to 16 thought more that the Archimedes' constant should be written after that, and after that age, there was a greater perception that both are possible without confusion of meaning. It can be seen that the change in students' perception has emerged through school education on natural mathematical written order of characters after middle school courses. From this point of view, the most common perception can be that if there is no confusion in meaning, then both expressions are possible.
Proceedings of the Korean Radioactive Waste Society Conference
/
2004.06a
/
pp.147-157
/
2004
The production of $^{14}C$ occurs in the Moderator(MOD), Primary Heat Transport System (PHTS), Annulus Gas System(AGS) and Fuel in the CANDU reactor. Among the four systems, The MOD system is the largest contributor to $^{14}C$ production(approximately 94.8%). $^{14}C$ is distributed of $^{14}CO_2$, $H_2^{14}CO_3$, $H^{14}{CO_3}^-$ and $^{14}{CO_3}^{2-}$ species as a function of the pH of water. Of these species, $H_2^{14}CO_3$ and $H^{14}{CO_3}^-$ form are predominant because the pH of MOD system is > 5. In this paper, adsorption-desorption characteristics of bicarbonate ion (${HCO_3}^-$) by IRN 150 resin was investigated. ${HCO_3}^-$ ion existed in neutral condition(app. pH 7)was reacted with ion exchange resin (IRN-150) and saturated with it. Then $NaNO_3$ and $Na_3PO_4$ solutions selected as extraction materials were used to make an investigation into feasibility of ${HCO_3}^-$ extraction from resin saturated with ${HCO_3}^-$. Desorption of $CO^{2+}$ and $Cs^+$ ion by $Na^+$ ion was not occurred, and desorption of ${HCO_3}^-$ ion by ${NO_3}^-$ and ${PO_4}^{3-}$ was occurred slowly. Also, the status of ion exchange which is used in Wolsong NPPs and generation of spent resin yearly were surveyed.
Transactions of the Korean Society of Mechanical Engineers B
/
v.39
no.1
/
pp.97-107
/
2015
An analytical model was developed to estimate the viscous and squeeze-film damping ratios of heat exchanger tubes subjected to a two-phase cross-flow. Damping information is required to analyze the flow-induced vibration problem for heat exchange tubes. In heat exchange tubes, the most important energy dissipation mechanisms are related to the dynamic interaction between structures such as the tube and support and the liquid. The present model was formulated considering the added mass coefficient, based on an approximate model by Sim (1997). An approximate analytical method was developed to estimate the hydrodynamic forces acting on an oscillating inner cylinder with a concentric annulus. The forces, including the damping force, were calculated using two models developed for relatively high and low oscillatory Reynolds numbers, respectively. The equivalent diameters for the tube bundles and tube support, and the penetration depth, are important parameters to calculate the viscous damping force acting on tube bundles and the squeeze-film damping forces on the tube support, respectively. To calculate the void fraction of a two-phase flow, a homogeneous model was used. To verify the present model, the analytical results were compared to the results given by existing theories. It was found that the present model was applicable to estimate the viscous damping ratio and squeeze-film damping ratio.
Ku, Gwan-Woo;Kang, Shin-Kwang;Won, Tae-Hee;Kim, Si-Wook;Yu, Jae-Hyun;Na, Myung-Hoon;Lim, Seung-Pyung;Lee, Young
Journal of Chest Surgery
/
v.35
no.10
/
pp.750-754
/
2002
Primary cardiac tumors are rare and about 20~25% of primary cardiac tumors are malignant. Moreover, primary malignant mesenchymoma of the heart is extremely rare. Recently, we have experienced two cases of cardiac malignant mesenchymoma. In the first case, malignant mesenchymoma which was originated from the posterior wall of the left atrium obstructing the mitral orifice was revealed pathologically in a 61-year-old woman with mitral regurgitation. The mass, which was 2.7$\times$3.7cm in size on the posterior wall of left atrium, was extended to the posteromedial commissure and annulus of the mitral valve. The mass was resected partially without excision of the left atrial free wall. She was discharged after 30 days without any problems and she received chemotherapy and followed up for 19months. The second case was a 4$\times$5cm in size, friable, yellow-whitish multilobulated mass in the left atrium which was originated from the left lower pulmonary vein. Multiple minor tumor nodules were found in the wall of the left atrium and the posterior leaflet of mitral valve. Partial mass excision and mitral valve replacement were performed.
Seo, Sei Young;Oh, Jin Hee;Kim, Jong-Hyun;Han, Ji-Whan;Lee, Kyung-Yil;Koh, Dae Kyun
Clinical and Experimental Pediatrics
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v.48
no.8
/
pp.901-906
/
2005
Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Yet the etiology of KD is still unknown and diagnosis depends on the exclusion of other diseases and the clinical manifestations meeting the defined criteria. Young infants frequently show atypical clinical courses and are frequently complicated with coronary aneurysms. Some cases show thrombocytopenia, which is known as one of the risk factors for complications with coronary aneurysms. So, a high index of suspicion is the most important factor for the diagnosis of KD in very young infants or adolescents whose clinical courses are equivocal. We report herein on a case of KD in an 80-day-old female infant with fever and seizure with bloody stool; laboratory findings were those of sepsis with disseminated intravascular coagulopathy. In spite of aggressive treatments, fever and thrombocytopenia persisted for two weeks and huge coronary aneurysms developed at the third week in all three major coronary arteries; the diameter of the right one was as large as the aortic annulus. Three months later, huge pulsatile masses developed in both axillas; these were found to be huge axillary aneurysms defined very clearly on multi-detector CT scan. She has been under follow up with antiplatelets and anticoagulation therapy with poor regression of the aneurysms.
The purpose of this study is to investigate the potential of a novel tissue engineering approach to regenerate intervertebral disc. In this study, thermosensitive scaffold (chitosan-Pluronic hydrogel) and nanofiber were used to replace the nucleus pulposus (NP) and annulus fibrosus of a degenerated intervertebral disc, leading to an eventual regeneration of the disc using the minimally invasive surgical procedure and organ culture. In preliminary study, disc cells were seeded into the scaffolds and cellular responses were assessed by MTT assay and scanning electron microscopy (SEM). Based on these results, we could know that tissue engineered scaffolds might provide favorable environments for the regeneration of tissues. Organ culture was performed in fresh porcine spinal motion segments with endplates on both sides. These spinal motion segments were classified into three groups: control (Intact), injured NP (Defect), and inserting tissue engineered scaffolds (Insert). The specimens were cultivated for 7 days, subsequently structural stability, cell proliferation and morphological changes were evaluated by the relaxation time, quantity of DNA, GAG and histological examination. In these results, inserting group showed higher relaxation time, reduced decrement of DNA contents, and accumulated GAG amount. Consequently, the tissue engineered scaffolds used in this study seen to be a promising base scaffolds for regenerative intervertebral disc due to its capacity to absorb external dynamic loading and the possible ideal environment provided for disc cell growing.
Growth of Ammodytes personatus was investigated based on the specimens collected in the costal waters of Shinsudo, Sacheon from March 20 to December 14, 1988. Age determination based on otolith. The rings in the otolith were used as the basis for age annulus. The time of ring formation was estimated to one time per year in May far 1st ring group and March for 2nd ring group. The spawning season peaked in December. It takes approximately 16 months for the first ring and 11 months for the second ring to form in the otolith. The opaque zone was formed and marked over summer at 1st ring group and spawning mark at 2nd ring group. The relationship between the total length(TL) and otolith radius(R), and body weight(BW) were represented respectively as follows: TL=29.17+182.9R, BW=$4.9{\times}10^{-8}TL^{3.9587}$. Von Bertalanffy growth model is $TL_t$ = 177.273 ($1_e^{-0.040(t+7.332)}$), Robertson growth model is $TL_t=\frac{150.275}{1+2.085e^{-0.099t}}$ and Gompertz growth model is $TL_t=157.551e^{-1.214exp(-0.069t)}$.
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