• 제목/요약/키워드: Animal

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Sterile Panniculitis in a Maltese Dog

  • Hwang, Mee-Na;Lee, Jae-Hee;Han, Man-Gil;Suk, Joo-Yeun;Gwon, Ryu-Hee;Jung, In-Sung
    • 한국임상수의학회:학술대회논문집
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    • 한국임상수의학회 2007년도 춘계학술대회
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    • pp.109-109
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    • 2007
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Rectal Plasmacytoma in a Maltese Dog

  • Kwon, Hyun-Ju;Kim, Hyun-Wook;Choi, Ji-Hye;Jang, Jae-Young;Kim, Hye-Jin;Kim, Sung-Soo;Choi, Hee-Yeon;Seo, Ji-Min;Lee, Min-Jung;Jung, Ji-Young;Lee, Hae-Kyung;Kim, Tae-Eun
    • 한국임상수의학회:학술대회논문집
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    • 한국임상수의학회 2007년도 추계국제학술대회 및 컨퍼런스
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    • pp.601-601
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    • 2007
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송아지에서 발생한 중증 크립토스포리듐 증 증례 (Fatal cryptosporidiosis in a calf)

  • 백강현;이현경;이경현;김하영;박중원;이보람;허지웅;이명헌;배유찬
    • 대한수의학회지
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    • 제54권4호
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    • pp.257-260
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    • 2014
  • A calf suffering from diarrhea was admitted to the Animal and Plant Quarantine Agency for diagnostic evaluation. Postmortem examination revealed that the mesenteric lymph node was enlarged and small intestine wall was thin. Microscopically, a large number of small round organisms were attached to the small intestine villi. Villous atrophy and proprial neutrophil infiltration were also observed. Based on modified Ziehl-Neelsen staining, electron microscopy, and ELISA results, the calf was diagnosed with fatal cryptosporidiosis.

Genetic Variation and Genetic Relationship of Seventeen Chinese Indigenous Pig Breeds Using Ten Serum Protein Loci

  • Mo, D.L.;Liu, B.;Wang, Z.G.;Zhao, S.H.;Yu, M.;Fan, B.;Li, M.H.;Yang, S.L.;Zhang, G.X.;Xiong, T.A.;Li, K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권7호
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    • pp.939-945
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    • 2003
  • Seventeen Chinese indigenous pig breeds and three introduced pig breeds had been carried out by means of vertical polyacrylamide gel electrophoresis (PAGE). According to the results, eight serum protein loci were highly polymorphic except Pi-2 and Cp. The polymorphism information content (PIC) of Hpx was the highest (0.5268), while that of Cp was the lowest (0.0257). The population genetic variation index showed that about 84% genetic variation existed in the population, and the rest of 16% distributed between the populations. The genetic variation of Yimeng black pig and Duroc were the highest and the lowest, respectively. The genetic variation of Chinese indigenous pig breeds was much more than that of exotic groups. Genetic distance results showed that Chinese indigenous pig breeds were classified into four groups with the three introduced pig breeds clustered into another group. The results also supported the geographic distribution of Chinese indigenous pig breeds in certain extent.

Enhanced biological effects of Phe140Asn, a novel human granulocyte colony-stimulating factor mutant, on HL60 cells

  • Chung, Hee-Kyoung;Kim, Sung-Woo;Byun, Sung-June;Ko, Eun-Mi;Chung, Hak-Jae;Woo, Jae-Seok;Yoo, Jae-Gyu;Lee, Hwi-Cheul;Yang, Byoung-Chul;Kwon, Moo-Sik;Park, Soo-Bong;Park, Jin-Ki;Kim, Kyung-Woon
    • BMB Reports
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    • 제44권10호
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    • pp.686-691
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    • 2011
  • Granulocyte colony-stimulating factor (G-CSF) is a cytokine secreted by stromal cells and plays a role in the differentiation of bone marrow stem cells and proliferation of neutrophils. Therefore, G-CSF is widely used to reduce the risk of serious infection in immunocompromised patients; however, its use in such patients is limited because of its non-persistent biological activity. We created an N-linked glycosylated form of this cytokine, hG-CSF (Phe140Asn), to assess its biological activity in the promyelocyte cell line HL60. Enhanced biological effects were identified by analyzing the JAK2/STAT3/survivin pathway in HL60 cells. In addition, mutant hG-CSF (Phe140Asn) was observed to have enhanced chemoattractant effects and improved differentiation efficiency in HL60 cells. These results suggest that the addition of N-linked glycosylation was successful in improving the biological activity of hG-CSF. Furthermore, the mutated product appears to be a feasible therapy for patients with neutropenia.