• Journal of Biomedical Engineering Research
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• v.28 no.2
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• pp.258-264
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• 2007

Spatiotemporal changes of brain rhythmic activity at a certain frequency have been usually monitored in real time using scalp potential maps of multi-channel electroencephalography(EEG) or magnetic field maps of magnetoencephalography(MEG). In the present study, we investigate if it is possible to implement a real-time brain activity monitoring system which can monitor spatiotemporal changes of cortical rhythmic activity on a subject's cortical surface, neither on a sensor plane nor on a standard brain model, with a high temporal resolution. In the suggested system, a frequency domain inverse operator is preliminarily constructed, considering the individual subject's anatomical information, noise level, and sensor configurations. Spectral current power at each cortical vertex is then calculated for the Fourier transforms of successive sections of continuous data, when a single frequency or particular frequency band is given. An offline study which perfectly simulated the suggested system demonstrates that cortical rhythmic source changes can be monitored at the cortical level with a maximal delay time of about 200 ms, when 18 channel EEG data are analyzed under Pentium4 3.4GHz environment. Two sets of artifact-free, eye closed, resting EEG data acquired from a dementia patient and a normal male subject were used to show the feasibility of the suggested system. Factors influencing the computational delay are investigated and possible applications of the system are discussed as well.

• Journal of Korean Academy of Nursing
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• v.25 no.1
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• pp.17-29
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• 1995

This study was done to analysis data on breastfeeding mothers. This stud was conducted using data from telephone counseling in one metropolitan area. The subjects who had received consultation about breastfeeding were 100 breastfeeding mothers. The period of consultation was from Mar. 9, 1994 to August 23, 1994. Consultants were referred from UNICEF, hospitals, TV, newspapers or magazines. Analysis of the problem patterns resulted in 11 classifications. These were physio -anatomical factors(11 cases) , psychological factors(15 cases), breastfeeding methods(21 cases), breastfeeding intervals and frequency(19 cases) , disease in the breastfeeding mothers(13 cases), disease in the babies (12 cases), lack of support (4 cases), food and drugs while breastfeeding(5 cases), weaning(11 cases), others(27 cases). The highest frequency was for breastfeeding methods (21 cases). When the contents of the counselling were analyzed for the 100 cases, 36 problem patterns were identified. Patterns with over 10 responses were diarrhea, insufficient milk supply, sore and cracked nipples, weaning, inverted nipples and jaundice. The age of infants when mothers were telephoned was as below : 1 week(28 cases), 2 weeks(12 cases), 3-4 weeks(18 cases), 5-8 weeks(7 cases), 9 weeks-3 menths(4 cases), 4 menths-6 months(12 cases), over 6 months(2 cases), and the number of pregnant women was 12. The nursing diagnosis were classified according to problem patterns and each diagnosis was assigned an appropriate Problem Pattern The total number of nursing diagnoses was 22. When clients are referred for counselling nurses need guidelines about problems, possible causes and nursing. In this study, the example of guidelines for sore nipples is suggested. The recommendations based on the telephone counseling results are as follows : Prenatal education about the advantages of breastfeeding and breast care, and home visits after delivery for counseling related to breastfeeding. During the hospital stay, nursing intervention such as education on breastfeeding methods using slides, audio-visual tapes, pamphlets are needed as well as an initial trial of breastfeeding. Further research is indicated on the perceived lack of breast milk and on the effectiveness of nursing interventions to pro-mote breastfeeding.

• Fashion & Textile Research Journal
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• v.22 no.5
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• pp.650-659
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• 2020

The present study provides reference data required for the design of clothing for the elderly by analyzing the body surface area during fitness motion based on 3D scan data of Korean elderly women. This study was conducted with the procedures of (1) survey of motions and main muscles for fitness, (2) acquisition of 3D scan data, and (3) analysis of rate of change for body surface area during fitness motion. Acquisition of 3D body scan data was obtained from seven elderly females (age: 64-77). We selected 66 anatomical landmarks (40 upper body and 22 lower body) by referring to previous studies. Body surface was segmented by connecting the landmarks marked on the 3D scan data acquired. Analysis of body surface area was conducted in terms of the change rate of surface area in 9 postures of elbow 0°, 90° and 180° for flexion, shoulder 90°, 180° for flexion, shoulder 0°, 180° for abduction, hip 90° for flexion, and knee 90° for flexion compared to the those in the standing posture. The amount of changes in body surface area were 12%-62% in the upper body, 15%-77% in the arm, and 10%-51% in the lower body. A future study on the rate of change of body surface length is needed; in addition, a study on how to apply the results of body surface area and body surface length analysis to clothing pattern design is also necessary.

• Development and Reproduction
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• v.21 no.3
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• pp.237-247
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• 2017

Mammalian spermatogenesis occurs in a precise and coordinated manner in the seminiferous tubules. One of the attempts to understand the detailed biological process during mammalian spermatogenesis at the molecular level has been to identify the testis specific genes followed by study of the testicular expression pattern of the genes. From the subtracted cDNA library of rat testis prepared using representational difference analysis (RDA) method, a complimentary DNA clone encoding type III member of a DnaJ family protein, DnaJC18, was cloned (GenBank Accession No. DQ158861). The full-length DnaJC18 cDNA has the longest open reading frame of 357 amino acids. Tissue and developmental Northern blot analysis revealed that the DnaJC18 gene was expressed specifically in testis and began to express from postnatal week 4 testis, respectively. In situ hybridization studies showed that DnaJC18 mRNA was expressed only during the maturation stages of late pachytene, round and elongated spermatids of adult rat testis. Western blot analysis with DnaJC18 antibody revealed that 41.2 kDa DnaJC18 protein was detected only in adult testis. Immunohistochemistry study further confirmed that DnaJC18 protein, was expressed in developing germ cells and the result was in concert with the in situ hybridization result. Confocal microscopy with GFP tagged DnaJC18 protein revealed that it was localized in the cytoplasm of cells. Taken together, these results suggested that testis specific DnaJC18, a member of the type III DnaJ protein family, might play a role during germ cell maturation in adult rat testis.

• The Journal of Internal Korean Medicine
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• v.39 no.4
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• pp.676-685
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• 2018

Objectives: The aim of this study was to estimate the single oral toxicity of Peucedani Radix (PR) ethanol extracts. PR is one of the important herbs for removal of phlegm, the viscous turbid pathological product that can accumulate in the body and cause a variety of diseases. However, research on the pharmacologic toxicity of PR is lacking. Methods: In this study, PR was orally administered to 5-week-old male ICR mice at an oral dose of 2,000, 3,000, or 5,000 mg/kg. After a single-dose administration, the mortality and behavioral changes were observed daily and body weights were measured every two days. After 14 days, the organ weight, organ index, macroscopy, hematological analysis, and serum biochemistry analysis were determined. Results: No mortality, body weight changes, abnormal behavioral changes, or anatomical signs of toxicity were found. The organ weight, organ index, hematological analysis, and serum biochemistry analysis were also within the normal ranges. Conclusions: These results suggest that the 50% lethal dose of PR is more than 5,000 mg/kg. This could indicate that PR is a safe drug without acute toxicity and side effects.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.4
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• pp.365-370
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• 2014

The intrinsic concepts of the three yin and three yang diseases in is unclear yet in spite of considerable controversy. In order to answer these problems, the structures of pathological transmission and anatomical terms used in the text were analyzed first. On these structural bases, the theoretical background and differential therapeutic principles of three yin and three yang disease classification. The organic structures frequently used in the text were heart, stomach, pancreas, blood chamber and urinary bladder, and the important regions in the transmission were chest, flank, epigastrium, abdomen, hypogastrium, groin on the other hand. When a host is invaded by extrinsic pathogen, an affinity is formed between the two based on the similarity of epidermal density condition and nutrient-defense features and existing disorders in the body. And then the symptoms show in 3 stages with 6 patterns in the general infective diseases. The initial stage is the period that the syndrome is limited in the external flesh area, and it mainly corresponds with taiyang bing besides the other exterior patterns of 3 yang and 2 yin bing. The middle stage is to the climax after the end of initial stage and it corresponds with mainly yangming bing including shaoyang and taiyin bing. In the terminal stage, the host gradually falls into exhaustive step or recovery phase, corresponding with shaoyin and jueyin bing. Conclusively, these dual meanings of three yang and yin should be a first guide and principle of treatment against various infective diseases.

• Journal of the Korean Wood Science and Technology
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• v.38 no.2
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• pp.108-116
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• 2010

This paper explains the effects of wood drying on treatability (as determined by water uptake) of Japanese red pine (Pinus densiflora S. et Z.) at the sevenmoisture content (MC) levels above and below the fiber saturation point (FSP). According to the experimental results, it was found that water uptake (as the percentage of void volume filledwith distilled water, VVF%) was influenced by level of moisture content and percentage of void volume filled was improved effectively by kiln drying process. A significant relationship between moisture content and treatability was established. Permeability and liquid uptake were decreased above the FSP due to the effect of the less void space available in wood. Even though increased liquid uptake was observed at lower moisture content, no significant differences was observed moisture content below 20%. Therefore, this species need to be initially dried below FSP before treated with liquids. But drying moisture content below 10% might not be economical for the commercial purpose comparing drying the wood between 10 and 20% moisture content. The result of this study inferred that the treatability of pine wood can be improved by reducing the moisture content up to a certain level of 10~20% for allowing better performance.

• Journal of the Korean Wood Science and Technology
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• v.19 no.3
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• pp.7-18
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• 1991

목재(木材)의 액체침투성(液體浸透性)을 연구(硏究)하기 위하여 국내(國內)에 있는 침엽수재(針葉樹材)와 활엽수재(闊葉樹材)의 주요수종(主要樹種)을 대상으로 축방향(軸方向), 방사방향(放射方向), 접선방향(接線方向)의 침투(浸透)를 각각 조사(調査)하였다. 또한 방사(放射) 및 접선방향(接線方向)의 주요(主要) 침투경로(浸透經路)를 광학현미경(光學顯微鏡)으로 관찰(觀察)하였다. 실험결과(實驗結果)는 다음과 같다. 1. 종침투(縱浸透)는 침(針) 활엽수재(闊葉樹材)모두 1% $NH_4OH$ 처리(處理)시 침투성(浸透性)이 가장 컸으며 수종(樹種)에 따른 침투성(浸透性)의 차이(差異)는 침엽수재(針葉樹材)인 잣나무가 활엽수재(闊葉樹材)인 물푸레나무와 현사시나무 보다는 더 컸으며 관엽수재내(關葉樹材內)에서는 물푸레나무가 현사시나무보다 침투성(浸透性)이 더 큰 것으로 나타났다. 2. 횡침투(橫浸透)는 침엽수재(針葉樹材)에 있어서 침투면별(浸透面別) 침투량(浸透量)은 접선단면(接線斷面)이 방사단면(放射斷面)보다 훨씬 컸으며, 활엽수재(闊葉樹材)의 경우는 환공재(環孔材)에서는 접선단면(接線斷面)이 방사단면(放射斷面)보다 침투량(浸透量)이 컸으나, 산공재(散孔材)에서는 수종간(樹種間)의 변이(變異)가 컸다. 활엽수재(闊葉樹材)의 환공재(環孔材) 모두 방사조직(放射組織)이 횡침투(橫浸透)에 미치는 영향(影響)은 침엽수재(針葉樹材)만큼 크지 않았다. 침투(浸透)깊이도 침엽수재(針葉樹材)가 활엽수재(闊葉樹材)보다 컸으며, 활엽수재(闊葉樹材)는 수종간(樹種間)의 차이(差異)가 심했다. 3. 침투경로(浸透經路)를 보면 침엽수재(針葉樹材)는 방사유세포(放射柔細胞), 만재부(晩材部)의 소가도관(小假導管)이 주도적(主導的)인 역할을 하였으며, 활엽수재(闊葉葉材)도 역시 방사조직(放射組織)을 통해서 침투(浸透)가 이루어지지만 수종간(樹種間)에 방사조직(放射組織)의 침투양식(浸透樣式)과 침투속도(浸透速度)가 달랐다.

• Archives of Plastic Surgery
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• v.45 no.5
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• pp.395-402
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• 2018

Increased emphasis on competency-based learning modules and widespread departure from traditional models of Halstedian apprenticeship have made surgical simulation an increasingly appealing component of medical education. Surgical simulators are available in numerous modalities, including virtual, synthetic, animal, and non-living models. The ideal surgical simulator would facilitate the acquisition and refinement of surgical skills prior to clinical application, by mimicking the size, color, texture, recoil, and environment of the operating room. Simulation training has proven helpful for advancing specific surgical skills and techniques, aiding in early and late resident learning curves. In this review, the current applications and potential benefits of incorporating simulation-based surgical training into residency curriculum are explored in depth, specifically in the context of plastic surgery. Despite the prevalence of simulation-based training models, there is a paucity of research on integration into resident programs. Current curriculums emphasize the ability to identify anatomical landmarks and procedural steps through virtual simulation. Although transfer of these skills to the operating room is promising, careful attention must be paid to mastery versus memorization. In the authors' opinions, curriculums should involve step-wise employment of diverse models in different stages of training to assess milestones. To date, the simulation of tactile experience that is reminiscent of real-time clinical scenarios remains challenging, and a sophisticated model has yet to be established.

• Journal of Korea Multimedia Society
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• v.21 no.6
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• pp.678-684
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• 2018

In order to broaden the indication of middle ear implant, research has been actively conducted on the reverse output method that stimulates the round window. However, it is very difficult to transmit the vibration output effectively because the indivisual anatomical difference of the round window niche is very large and also the visual field is not secured even by a skilled otolaryngologic surgeon. In this paper, we propose a new reverse stimulation method of middle ear implants that transmits energy to the inner ear by using air as a medium. This can compensate for the disadvantages of the conventional method of transmitting vibration energy and minimizes the energy transfer efficiency interference due to the combination of the excitation point and the output device. It was shown that forward and backward transfer characteristics were obtained by cadaveric experiments, and it was shown that it can overcome the acoustical impedance of high round window and transmit energy to inner ear. The receiver, which is the output device of the conventional hearing aids, can generate a constant volume velocity, so it can have a high output at a limited volume, such as a round window niche. So, suggested method can overcome the high acoustical impedance of the round window and deliver acoustic energy to the inner ear.