• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4447-4453
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• 2013

Purpose: To investigate the risk factors for anastomotic leakage (AL) after anterior resection for rectal cancer with a double stapling technique. Patients and Methods: Between January 2004 and December 2011, 753 consecutive patients in Jiangsu Cancer Hospital and Research Institute diagnosed with rectal cancer and undergoing anterior resection with a double stapling technique were recruited. All patients experienced a total mesorectal excision (TME) operation. Additionally, decrease of postoperative tumor supplied group of factors (TSGF), which have not been reported before, was proposed as a new indicator for AL. Univariate and multivariate analysis were performed to determine risk factors for AL. Results: AL was detected in 57 (7.6%) of 753 patients with rectal cancer. The diagnosis of anastomotic leakage was confirmed between the 6th and 12th postoperative day (POD; mean 8th POD). After univariate analysis and multivariate analysis, age (p<0.001), gender (p=0.002), level of anastomosis (p<0.001), preoperative body mass index (BMI) (p=0.001) and reduction of TSGF in 5th POD was less than 10 ${\mu}/ml$ (p<0.001) were selected as 5 independent risk factors for AL. It was also indicated that a temporary defunctioning transverse ileostomy (p=0.04) would decrease the occurrence of AL. Conclusion: AL after anterior resection for rectal carcinoma is related to elderly status, low level site of the tumor (below the peritoneal reflection), being male, preoperative BMI and the decrease of TSGF in $5^{th}$ POD is less than 10 ${\mu}/ml$. Preventive ileostomy is advisable after TME for low rectal tumors to prevent AL.

• Journal of Chest Surgery
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• 제56권5호
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• pp.362-366
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• 2023

The stomach has become the most commonly used site for grafts to replace the esophagus in esophageal cancer surgery because of its good blood supply and ability to enable single-reconstruction anastomosis. However, anastomotic failure is a serious complication after esophageal cancer surgery. Unlike anastomotic leakage due to local ischemia, gastric tube necrosis is a life-threatening condition with a high mortality rate. Gastric tube necrosis involves extensive ischemia due to a decreased blood supply, and an urgent operation is mandatory in most cases. Endoscopic vacuum therapy (EVT) has been used for anastomotic leakage after esophageal surgery. In recent years, it has been successfully used for more extensive disease, including large esophageal perforation as an indication for reoperation. Hence, we report a case of extensive gastric tube necrosis treated by EVT after an Ivor Lewis operation.

• Journal of Chest Surgery
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• 제39권3호
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• pp.208-213
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• 2006

배경: 식도암 수술에 있어서 문합 부위 합병증의 발생은 문합 방법이나 위치와 관계가 있는 것으로 알려져 있다. 이에 저자들은 식도암으로 식도절제 및 식도재건술을 시행 받은 환자에서 문합 방법 및 위치와 누출 또는 협착 발생과의 연관성에 대해 조사하였다. 대상 및 방법: 1993년 8월부터 2003년 5월까지 식도암으로 식도재건술을 시행 받은 321명의 환자를 대상으로 하여 문합 방법, 문합 위치 ,합병증의 발생에 대해 조사하였다. 환자군의 평균 연령은 64.5$\pm$4.9세(37${\~}$94세)였고, 성비는 남자 3001 명($93.5\%$), 여자 21명($6.5\%$)이었다. 결과: 문합부위의 누출은 7예($2.2\%$)에서 발생하였다. 부위별로는 경부 문합에서 3예($4.1\%$), 흉부 문합에서 4예($1.6\%$)로 문합 위치에 따른 차이는 없었다. 문합 방법은 stapler 봉합을 한 경우에서 4예($1.6\%$), semi-stapler 봉합을 한 경우에서 3예($9.1\%$), 수봉합한 경우는 0예($0.0\%$)로 문합 방법에 따른 누출의 차이가 없었다. 문합 부위의 협착은 52예($16.2\%$)에서 발생하였고, 부위별로는 경부 문합에서 2예($2.7\%$), 흉부 문합에서 50예($20.2\%$)로 문합 위치에 따른 차이가 있었다(p<0.001). 문합 방법별로는 stapler봉합이 49예($20.0\%$), semi-stapler봉합 1예($3.0\%$), 수봉합 2예($4.7\%$)로 stapler 봉합에서 유의하게 높았다(p<0.001). 결론: 식도암 환자의 식도재건술에 있어서 문합방법은 문합 부위 누출에 의미 있는 영향을 미치지 않았다. 그러나, 문합 부위의 협착과 관련하여 stapler 봉합은 semi-stapler 봉합 및 수봉합보다 높은 빈도로 협착이 나타났다. 그러므로 stapler 문합시 협착을 줄이기 위해서는 문합 방법의 개선이 필요하다고 생각한다.

• Journal of Chest Surgery
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• 제53권4호
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• pp.222-225
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• 2020

Owing to varying clinical definitions of anastomotic stricture following esophageal reconstruction, its reported incidence rate varies from 10% to 56%. Strictures adversely impact patients' quality of life. Risk factors, such as the anastomosis method, leakage, ischemia, neoadjuvant chemoradiotherapy, and underlying disease have been mentioned, but conflicting information has been reported. Balloon dilation is regarded as a safe and effective treatment method for patients with benign anastomotic strictures. Reoperations are seldom required. The etiology and management of anastomotic strictures are reviewed in this article.

• Journal of Chest Surgery
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• 제28권11호
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• pp.1025-1031
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• 1995

Thirty patients who underwent esophageal resections due to esophageal carcinoma and benign strictures, and esophagovisceral anastomoses were performed by hand suture in 11 patients[Group I and by using the end to end anastomosis[EEA stapler in 19 patients[Group II . Anastomoses were performed in the thoracic cavity in 24 patients[Right 19, Left 5 and in the cervical area in 6 patients. There was one operative mortality[3.3% in a cancer patient who underwent Ivor-Lewis operation using EEA stapler. She expired on POD 38 days due to renal failure and sepsis. There were two anastomotic leakage in the sutured group and no anastomotic leakage in the stapled group. Late anastomotic strictures occurred in 10 patients[52.6% in the stapled group compared to 2 patients[18.1% in the sutured group. Most of the patients with late anastomotic strictures responded to one or two trials of TTS dilations. Using EEA stapler in performing esophagovisceral anastomosis is a safe method with acceptable range of complication rate, and total admission period after the operation for group I was 30.3 days compared to 25.4 days in group II although it had no clinical significance. The follow up was possible in 23 patients; 5 patients in group I died within mean 12.6 months and 9 patients in group II within mean 14.2 months.

• Journal of Chest Surgery
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• 제29권9호
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• pp.1003-1009
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• 1996

식도위장문합술에서 주로 사용되는 원형기계를 사용하는 문합술은 편리하며 누공발생률이 적은 술기이나 문합부의 협착이 잘 생기며 이는 문합기가 작은 경우에 발생빈도가 높다. 경부에서 식도위장문합시 기계문합식으로 편리하게 수술하면서 협착을 방지하는 수술수기로흉강경용 봉합기를 사용하는 방법을 고폰하여서 임상적용한 결과를 보고한다. 식도암 환자 13례에서 식도재건술에 흉강경용 봉합기를 사용하여 경부식도위장 문합을 하였고 수술후 평균 8개월 관찰하여 문합부의 헙착발생을 관찰하였다. 식도암환자 13례중 수술후 사망한 1례를 제외한 12례중 1례에서 술후 위장궤사에 의한 누공이 있었고, 11례에서는 협착증상 없었다. 경부식도위장 문합술에서 흉강경용 봉합기를 사용한 결과 수술이 편리하고 협착 및 누공의 발생률은 매우 낮다. 흉강경용 봉합기 문합술식은수술이 간편하고,작은 내경의 식도와위장문합에서 생기는문합부의 협착을 방지할 수 있는 수술로 경부의식도장관문합의 변형술식으로 적용할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5427-5431
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• 2014

Aim: To evaluate the outcome of stapled versus sutured colo-rectal anastomosis after low anterior resection of mid-rectal carcinoma. Patients and Methods: A prospective study of fifty patients who underwent colo-rectal anastomosis following low anterior resection (LAR) of T2 mid-rectal cancers at the Egyptian National Cancer Institute during the time period from June 2010 to June 2013 was conducted. Classification was into two groups; a stapled anastomosis group I (25 patients) and a hand-sewn anastomosis group II (25 patients). All operations are evaluated regarding intra-operative complications such as anastomotic line bleeding, visceral injuries or major blood loss. The anastomotic time and operative time are documented for each operation. All patients are evaluated post-operatively for anastomotic leakage (AL), wound infection and ileus. Results: The distance of the tumor from the anal verge was $9.6{\pm}2.0cm$ in group I and $9.9{pm}2.4cm$ in group II. The mean operative time was $191.5{\pm}16.2min$ in the stapled group and $208{\pm}18.6min$ in the sutured group (p=0.002). The mean anastomotic times were $9.0{\pm}1.9min$ and $19.7{pm}12.2min$ (p=0.001). Anastomotic leakage developed in three (12.0%) patients in the stapled group and in four (16.0%) patients in the sutured group (p=1.000). Post-operative ileus was observed in 3 patients in group I and one patient in group II. Wound infection developed in three (12.0%) patients in the stapled group and four (16.0%) patients in the sutured group (p=1.000). Conclusion: Colo-rectal anastomosis after low anterior resection for mid rectal carcinoma can be conducted safely either by stapling or hand-sewn techniques; however the stapling technique showed shorter anastomotic and operative times with no significant advantages regarding intra- or post-operative complications or hospital stay.

• Journal of Yeungnam Medical Science
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• 제38권2호
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• pp.142-147
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• 2021

Background: This study was performed to investigate the association between cystographic anastomotic urinary leakage (UL) after retropubic radical prostatectomy (RRP) and early urinary incontinence (UI). Methods: The medical records of 53 patients who had undergone cystography after RRP at our institution between January 2015 and December 2018 were retrospectively analyzed. Cystography was performed 7 to 10 days after surgery. The duration of catheterization depended on the degree of UL, which was classified as mild, moderate, or severe. The study subjects were divided into the non-UL group and the UL group. Continence was defined as the use of no pads. The prostate was dissected in an antegrade fashion, and urethrovesical anastomosis was performed with a continuous suture. Results: Incontinence rates at 1 and 3 months postoperatively were significantly higher in the UL group than the non-UL group (83.3% vs. 52.2%, p=0.014 and 76.7% vs. 47.8%, p=0.030, respectively); however, those at 6 and 12 months were not significantly different (23.3% vs. 17.4%, p=0.597 and 4.3% vs. 10.0%, p=0.440, respectively). The severity of UL was not found to influence the duration of incontinence. The presence of cystographic anastomotic UL was found to be predictive of UI during the first 3 postoperative months (odds ratio, 3.3; p=0.045). Conclusion: The presence of anastomotic UL on cystography was associated with higher rates of UI in the early postoperative periods. However, incontinence rates in patients with or without anastomotic UL immediately after RRP equalized at 6 months and the severity of UL did not affect the duration of postoperative UI.

• 대한기관식도과학회지
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• 제5권2호
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• pp.143-152
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• 1999

Background : the technical modality of esophagogastric anastomosis plays an important part in the factors leading to anastomotic leakage and stricture. Objective : The objective of this study was to compare the leakage and stricture rates between the different anastomosis techniques. Materials and Methods : A retrospective study was undertaken in the patients with esophageal cancer who underwent a esophagectomy. Hand-sewn anastomosis was performed in one layer with interrupted sutures(Manual group). The stapler group was divided into two subgroups, such as PCEEA group and Endo-GIA group. Results : The differences of preoperative patient profiles between the groups were not significant. Overall mortality fates were 5% in manual group, 5% in PCEEA group and 11.5% in Endo-GIA group. Fewer anastomotic leakage occurred in manual group(5%) than in PCEEA group(10%) or in Endo-GIA group(15.4%). The postoperative stricture rate was higher in PCEEA group(35%) than in manual group(5%) or in Endo-GIA group(0%) Conclusion : Statistically, there were no significant differences in the anastomotic leakage and stricture rates between the hand-sewn and mechanical anastomosis. But the stricture rate was lower in the group using the linear stapling device and the leakage rate was lower in the hand-sewn group than the other groups.

• Journal of Chest Surgery
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• 제31권7호
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• pp.711-717
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• 1998

배경: 식도 문합술은 여러가지 문합방법과 문합재료를 사용해오고 있지만 문합부 누출과 협착이 다른 장문합에 비해 빈번하고 발생하면 중한 결과를 초래한다. 최근 저자들은 식도문합술 거의 대부분에서 polypropylene사를 이용한 단속단층 문합술을 시행하고 있다. 대상 및 방법: 이에 본 동아대학교병원 흉부외과에서는 1990년 4월부터 1996년 12월까지 시행한 식도문합술 90례의 임상결과를 분석하여 이 문합방법의 효용성을 알아 보기위해 이 연구를 시행하였다. 문합부 누출은 모두 5례(5.6%)에서 발생하였고 이 중 1례가 사망하였다. 결과: 문합부 협착은 수술 생존자를 대상으로 조사하였는데 모두 15례(17.4%)에서 발생하였다. 이 협착은 식도-위 문합술에서 가장 높은 빈도(22%)로 나타났고, 식도-대장문합술에서 가장 낮은 빈도(5%)로 나타났다. 이러한 결과는 다른 여러학자들의 자동 문합기에 의한 문합방법을 포함한 다른 문합방법들의 결과들과 비교할만한 결과였다. 결론: 저자들은 식도문합에 있어 이 문합방법은 식도폐쇄증 교정을 포함한 여러 식도문합에서 만족스러운 결과로 계속 사용되어 질 수 있으리라고 생각된다.