• 제목/요약/키워드: American Method

검색결과 707건 처리시간 0.023초

Evaluation of the classification method using ancestry SNP markers for ethnic group

  • Lee, Hyo Jung;Hong, Sun Pyo;Lee, Soong Deok;Rhee, Hwan seok;Lee, Ji Hyun;Jeong, Su Jin;Lee, Jae Won
    • Communications for Statistical Applications and Methods
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    • 제26권1호
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    • pp.1-9
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    • 2019
  • Various probabilistic methods have been proposed for using interpopulation allele frequency differences to infer the ethnic group of a DNA specimen. The selection of the statistical method is critical because the accuracy of the statistical classification results vary. For the ancestry classification, we proposed a new ancestry evaluation method that estimate the combined ethnicity index as well as compared its performance with various classical classification methods using two real data sets. We selected 13 SNPs that are useful for the inference of ethnic origin. These single nucleotide polymorphisms (SNPs) were analyzed by restriction fragment mass polymorphism assay and followed by classification among ethnic groups. We genotyped 400 individuals from four ethnic groups (100 African-American, 100 Caucasian, 100 Korean, and 100 Mexican-American) for 13 SNPs and allele frequencies that differed among the four ethnic groups. Additionally, we applied our new method to HapMap SNP genotypes for 1,011 samples from 4 populations (African, European, East Asian, and Central-South Asian). Our proposed method yielded the highest accuracy among statistical classification methods. Our ethnic group classification system based on the analysis of ancestry informative SNP markers can provide a useful statistical tool to identify ethnic groups.

공동주택 건축내장재의 TVOC 방출량에 관한 예측모델 연구 (A Study on Predication model for TVOC Emissions of Finishing material in Apartment House)

  • 김형수;이경회
    • KIEAE Journal
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    • 제2권3호
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    • pp.55-62
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    • 2002
  • While cognition about an environment pollution becomes important recently, the intense pollution measures about an indoor air environment is required. In the case of building indoor environment, over 80% of modem people is living in building and these days an interest of building interior materials which becomes a reason for indoor environmental pollution in public house, office, is increasing. An experimental measurement method of this study is as follows. (1) American EPA TO-17, ASTMD5116-97, measurement method in VOCs experiment of Japanese closet industrial association (2) 2.4-DNPH cartridge method in HCHO experiment, based on American EPA TO-11 and measurement method of Japanese closet industrial association (3) standard compound is analyzed by using HPLC after solvent extraction process (4) paint and furniture are selected as measurement objects (5) we also made small chamber to grasp an emission characteristic of HCHO and VOCs and to get an environment-amicable forecast model through it, then we developed the model which can forecast emission rate by chamber experiment.

Nonlinear Conte-Zbilut-Federici (CZF) Method of Computing LF/HF Ratio: A More Reliable Index of Changes in Heart Rate Variability

  • Vernon Bond, Jr;Curry, Bryan H;Kumar, Krishna;Pemminati, Sudhakar;Gorantla, Vasavi R;Kadur, Kishan;Millis, Richard M
    • 대한약침학회지
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    • 제19권3호
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    • pp.207-212
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    • 2016
  • Objectives: Acupuncture treatments are safe and effective for a wide variety of diseases involving autonomic dysregulation. Heart rate variability (HRV) is a noninvasive method for assessing sympathovagal balance. The low frequency/high frequency (LF/HF) spectral power ratio is an index of sympathovagal influence on heart rate and of cardiovascular health. This study tests the hypothesis that from rest to 30% to 50% of peak oxygen consumption, the nonlinear Conte-Zbilut-Federici (CZF) method of computing the LF/HF ratio is a more reliable index of changes in the HRV than linear methods are. Methods: The subjects of this study were 10 healthy young adults. Electrocardiogram RR intervals were measured during 6-minute periods of rest and aerobic exercise on a cycle ergometer at 30% and 50% of peak oxygen consumption ($VO_{2peak}$). Results: The frequency domain CZF computations of the LF/HF ratio and the time domain computations of the standard deviation of normal-to-normal intervals (SDNN) decreased sequentially from rest to 30% $VO_{2peak}$ (P < 0.001) to 50% $VO_{2peak}$ (P < 0.05). The SDNN and the CZF computations of the LF/HF ratio were positively correlated (Pearson's r = 0.75, P < 0.001). fast Fourier transform (FFT), autoregressive (AR) and Lomb periodogram computations of the LF/HF ratio increased only from rest to 50% $VO_{2peak}$. Conclusion: Computations of the LF/HF ratio by using the nonlinear CZF method appear to be more sensitive to changes in physical activity than computations of the LF/HF ratio by using linear methods. Future studies should determine whether the CZF computation of the LF/HF ratio improves evaluations of pharmacopuncture and other treatment modalities.

Modeling and experimental comparative analysis on the performance of small-scale wind turbines

  • Basta, Ehab;Ghommem, Mehdi;Romdhane, Lotfi;Abdelkefi, Abdessattar
    • Wind and Structures
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    • 제30권3호
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    • pp.261-273
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    • 2020
  • This paper deals with the design, wind tunnel testing, and performance analysis of small wind turbines targeting low-power applications. Three different small-size blade designs in terms of size, shape, and twisting angle are considered and tested. We conduct wind tunnel tests while measuring the angular speed of the rotating blades, the generated voltage, and the current under varying resistive loading and air flow conditions. An electromechanical model is also used to predict the measured voltage and power and verify their consistency and repeatability. The measurements are found in qualitative agreement with those reported in previously-published experimental works. We present a novel methodology to estimate the mechanical torque applied to the wind turbine without the deployment of a torque measuring device. This method can be used to determine the power coefficient at a given air speed, which constitutes an important performance indicator of wind turbines. The wind tunnel tests revealed the capability of the developed wind turbines to deliver more than 1225 mW when subject to an air flow with a speed of 7 m/s. The power coefficient is found ranging between 26% and 32%. This demonstrates the aerodynamic capability of the designed blades to extract power from the wind.

한국 성인 19-20세 안모의 실물사진계측분석학적 연구 (A PHOTOMETRIC STUDY OF MAXILLOFACIAL NORMALS IN 19 TO 20 YEARS-OLD KOREAN)

  • 전용일;김여갑
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제28권4호
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    • pp.318-325
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    • 2002
  • The primary method of diagnosis in craniofacial deformity patient is used by gross inspection. So we studied the frontal photometric measurements for maxillofacial Korean normals 44 male and 48 female ages 19 to 20 years were selected from a group of 92 healthy Kyung Hee university students in Seoul.. The photograph were taken with the subject sitting in head position parallel with interpapillary plane to the floor. During taking pictures, facial anallyser by Obwegeser(Martin Co., Germany) was used for correct measurements. The results of this study was followed. 1. In the linear measurements, all values of males were longer than those of females but middle third height and lower third height, facial width and nasal width of males were longer than those of females in p<0.05 2. The difference between right and left angular and linear measurement was insignificant. 3. In the horizontal facial ratios, interocular distance and nasal width were longer and mouth width were smaller in korean than in american(p<0.05). 4. In the vertical ratios, korean women have shorter facial height of lower third comparing with facial height of middle third than american(p<0.05). 5. In the vertical facial ratios, korean have smaller proportion below the stomion in the lower third department than american. (p<0.05).

High Frequency of Codon 12 but not Codon 13 and 61 K-ras Gene Mutations in Invasive Ductal Carcinoma of Breast in a South Indian Population

  • Sushma, C;Prasad, Shiva;Devi, Rudrama;Murthy, Sudha;Rao, TS;Naidu, CK
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권8호
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    • pp.3505-3508
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    • 2015
  • Background: Ras genes are thought to play an important role in human cancer since they have been found to be activated frequently in several types of tumors including breast cancer, where the overall incidence of K-RAS oncogene activation is 0-10%. Evaluation of K-RAS gene not only for mutational frequency but also for mutation types in this downstream signaling gene pathway is necessary to determine the mechanisms of action. The present study was conducted to test the hypothesis that K-RAS activation is involved in breast cancer risk of south Indian population. Materials and Methods: A total of 70 paired pathologically confirmed tumor and non-tumor tissues from the same breast cancer patients were analysed for most common K-RAS mutations of codon 12,13 and 61 by polymerase chain reaction followed by restriction digestion and direct nucleotide sequencing method. Results: We found that a high rate of homozygous and heterozygous mutations of codon 12, but not codon 13 and 61, may influence the invasive ductal carcinoma of breast risk in this study. Conclusions: Our study indicated that only codon 12 may be involved in initiating breast carcinogenesis in India.

Uncertainty quantification for structural health monitoring applications

  • Nasr, Dana E.;Slika, Wael G.;Saad, George A.
    • Smart Structures and Systems
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    • 제22권4호
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    • pp.399-411
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    • 2018
  • The difficulty in modeling complex nonlinear structures lies in the presence of significant sources of uncertainties mainly attributed to sudden changes in the structure's behavior caused by regular aging factors or extreme events. Quantifying these uncertainties and accurately representing them within the complex mathematical framework of Structural Health Monitoring (SHM) are significantly essential for system identification and damage detection purposes. This study highlights the importance of uncertainty quantification in SHM frameworks, and presents a comparative analysis between intrusive and non-intrusive techniques in quantifying uncertainties for SHM purposes through two different variations of the Kalman Filter (KF) method, the Ensemble Kalman filter (EnKF) and the Polynomial Chaos Kalman Filter (PCKF). The comparative analysis is based on a numerical example that consists of a four degrees-of-freedom (DOF) system, comprising Bouc-Wen hysteretic behavior and subjected to El-Centro earthquake excitation. The comparison is based on the ability of each technique to quantify the different sources of uncertainty for SHM purposes and to accurately approximate the system state and parameters when compared to the true state with the least computational burden. While the results show that both filters are able to locate the damage in space and time and to accurately estimate the system responses and unknown parameters, the computational cost of PCKF is shown to be less than that of EnKF for a similar level of numerical accuracy.

Production Practices for North American Ginseng: Challenges and Opportunities

  • Proctor John T.A.
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 2002년도 학술대회지
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    • pp.212-226
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    • 2002
  • North American ginseng production may have been maximized in the traditional growing areas in the last decade and further increases may be in woods grown root, for niche markets. The marketplace demands high quality roots. Most problems leading to low quality roots start with the grower and can be avoided. These include poor site selection, inadequate soil drainage, untimely and poorly applied pesticides, and neglect of good sanitary practices. Selection of low lying sites increased the plant damage from frost in Ontario in May 2002. Seeding is still the major method of propagation of ginseng in spite of some success in culturing different parts of the plant. Opportunities exist for shortening the stratification period of North American ginseng seed to allow spring planting. This may reduce disease incidence. Since only one-third of ginseng seed sown ultimately produces plants harvested after 3 years any approach that reduces disease incidence and improves seed germination, seedling emergence and crop stand must be pursued. Disease is the major problem in ginseng cutivation from seed stratification, soil preparation prior to planting, right through to drying of the roots. Replant disease remains as an unresolved problem and needs full characterization and new approaches for control. Much progress has been made in research and related extension activities in disease control although challenges will arise such as with Quintozene and its replacement with Quadris for control of diseases caused by Rhizoctonia. Decreased labor populations and increased associated costs for ginseng production are causing rapid mechanization in every aspect of the ginseng industry. Engineers, machinery dealers, and fabricators, and growers are being challenged to increase efficiency by mechanization.

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Low-Temperature Storage of Immature (Green) North American Ginseng Seed for Fall Planting

  • Proctor John T.A.;Louttit Dean
    • Journal of Ginseng Research
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    • 제30권2호
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    • pp.78-81
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    • 2006
  • Freshly harvested, immature (green) seeds of North American ginseng (Panax quinquefolius L.) were stratified for up to 3 years in plastic pails in controlled environment rooms at $5{\pm}1^{\circ}C$ for 9 months and then $21{\pm}2^{\circ}C$ for 3 months (Trt. 1, regular stratification), or continuously at $-2{\pm}0.2^{\circ}C$ (Trt. 2), or continuously at $3{\pm}0.2^{\circ}C$ (Trt. 3). During stratification at -2 and $3^{\circ}C$ embryos did not grow. On seeding in the field embryos grew rapidly and resultant seedlings were comparable to those from regularly stratified seed. Seedling emergence rate was acceptable at the industry expected rate of 68% after one year of storage, but not after two years storage when it declined to 17.5%. Seed rot was so severe in year 3 that no planting was carried out. Seedling and second year growth were similar at the three stratification temperatures; most importantly, root dry weight (economic yield) was similar. Low-temperature storage of freshly-harvested North American ginseng seed is an acceptable method for short-term retention of propagating material.

Finite element modeling of reinforced concrete beams externally bonded with PET-FRP laminates

  • Rami A. Hawileh;Maha A. Assad;Jamal A. Abdalla; M. Z. Naser
    • Computers and Concrete
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    • 제33권2호
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    • pp.163-173
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    • 2024
  • Fiber-reinforced polymers (FRP) have a proven strength enhancement capability when installed into Reinforced Concrete (RC) beams. The brittle failure of traditional FRP strengthening systems has attracted researchers to develop novel materials with improved strength and ductility properties. One such material is that known as polyethylene terephthalate (PET). This study presents a numerical investigation of the flexural behavior of reinforced concrete beams externally strengthened with PET-FRP systems. This material is distinguished by its large rupture strain, leading to an improvement in the ductility of the strengthened structural members compared to conventional FRPs. A three-dimensional (3-D) finite element (FE) model is developed in this study to predict the load-deflection response of a series of experimentally tested beams published in the literature. The numerical model incorporates constitutive material laws and bond-slip behavior between concrete and the strengthening system. Moreover, the validated model was applied in a parametric study to inspect the effect of concrete compressive strength, PET-FRP sheet length, and reinforcing steel bar diameter on the overall performance of concrete beams externally strengthened with PET-FRP.